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N20C hydrochloride

Catalog #: 2213
1 Citation Datasheet / COA / SDS

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2213 has been discontinued.
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N20C hydrochloride | CAS No. 1177583-87-7 | Additional NMDA Receptor Compounds
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Description: Non-competitive NMDA open-channel blocker

Chemical Name: 2-[(3,3-Diphenylpropyl)amino]acetamide hydrochloride

Purity: ≥98%

Product Details
Citations (1)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Selective, non-competitive NMDA receptor antagonist (IC50 = 5 μM); binds to the receptor-associated ion channel and prevents glutamate-induced Ca2+ influx. Displays neuroprotective activity in vivo. Brain-penetrant.

Technical Data

M.Wt:
304.82
Formula:
C17H20N2O.HCl
Solubility:
Soluble to 100 mM in water
Purity:
≥98%
Storage:
Desiccate at +4°C
CAS No:
1177583-87-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. A novel N-MthD.-aspartate receptor open channel blocker with in vivo neuroprotectant activity.
    Planells-Cases et al.
    J.Pharmacol.Exp.Ther., 2002;302:163

Product Datasheets

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Citation for N20C hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for N20C hydrochloride include:

1 Citation: Showing 1 - 1

  1. Enhancement of morphological plasticity in hippocampal neurons by a physically modified saline via phosphatidylinositol-3 kinase.
    Authors: Roy Et al.
    J Biol Chem  2014;9:e101883

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