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NGD 98-2 hydrochloride

Catalog #: 4315 Datasheet / COA / SDS

Discontinued Product

4315 has been discontinued.
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NGD 98-2 hydrochloride | CRF1 Receptor Antagonists
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Description: High affinity CRF1 antagonist

Chemical Name: N-(1-Ethylpropyl)-3-methoxy-5-[2-methoxy-4-(trifluoromethoxy)phenyl]-6-methyl-2-pyrazinamine hydrochloride

Purity: ≥98%

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Biological Activity

NGD 98-2 hydrochloride is a high affinity antagonist of corticotropin-releasing factor receptor 1 (CRF1) (Ki = 1 nM). Orally available and brain penetrant.

Technical Data

M.Wt:
435.87
Formula:
C19H24F3N3O3.HCl
Solubility:
Soluble to 100 mM in DMSO and to 5 mM in water with gentle warming
Purity:
≥98%
Storage:
Desiccate at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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