Nonactin

Catalog #: 2505 Datasheet / COA / SDS

Discontinued Product

2505 has been discontinued.
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Nonactin | CAS No. 6833-84-7 | Ionophores
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Description: Monovalent cation ionophore
Alternative Names: Ammonium Ionophore I

Chemical Name: (1R,2R,5R,7R,10S,11S,14S,16S,19R,20R,23R,25R,28S,29S,32S,34S)-2,5,11,14,20,23,29,32-Octamethyl-4,13,22,31,37,38,39,40-octaoxapentacyclo[32.2.1.17,10.116,19.125,28]tetracontane-3,12,21,30-tetrone

Purity: ≥93%

Product Details
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Biological Activity

Nonactin is a monovalent cation ionophore that displays selectivity for K+ and NH4+ (K+ = NH4+ > Na+ > Mg2+ > Li+ >> Ca2+ for nonactin-EVA sensor). Induces cation transport across artificial membranes. Also inhibits P-glycoprotein-mediated efflux of chemotherapeutic agents in multiple-drug resistant cancer cells. Antibiotic.

Technical Data

M.Wt:
736.94
Formula:
C40H64O12
Solubility:
Soluble to 10 mM in ethanol
Purity:
≥93%
Storage:
Desiccate at -20°C
CAS No:
6833-84-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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