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Octreotide

Catalog #: 1818 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
1818/1
Octreotide
1 Image
Description: sst2, sst3 and sst5 agonist
Alternative Names: SMS 201995,Sandostatin

Purity: ≥95%

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Biological Activity

Octreotide is a peptide agonist for sst2, sst3 and sst5 somatostatin receptors. IC50/Kd values (nM) at cloned human somatostatin receptors are: 290 - 1140 (sst1), 0.4 - 2.1 (sst2), 4.4 - 34.5 (sst3), > 1000 (sst4), and 5.6 - 32 (sst5).

Technical Data

M.Wt:
1019.24
Formula:
C49H66N10O10S2
Sequence:
FCFWKTCT

(Modifications: Phe-1 = D-Phe, Trp-4 = D-Trp, Thr-8 = Thr-ol, Disulfide bridge between 2-7)

Solubility:
Soluble to 1.20 mg/ml in water
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
83150-76-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Molecular pharmacology of somatostatin receptors.
    Hoyer et al.
    Naunyn Schmiedebergs Arch.Pharmacol., 1994;350:441
  2. Cloned somatostatin receptors: identification of subtype-selective peptides and demonstration of high affinity binding to linear peptides.
    Raynor et al.
    Mol.Pharmacol., 1993;43:838
  3. Drug design at peptide receptors. Somatostatin receptor ligands.
    Hannon et al.
    J.Mol.Neurosci., 2002;18:15

Product Datasheets

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