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Optovin

Catalog #: 4901
3 Citations Datasheet / COA / SDS

Discontinued Product

4901 has been discontinued.
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Optovin | CAS No. 348575-88-2 | TRPA1 Activators
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Description: Reversible photoactive TRPA1 activator

Chemical Name: 5-[[2,5-Dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-2-thioxo-4-thiazolidinone

Purity: ≥99%

Product Details
Citations (3)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Optovin is a reversible photoactive TRPA1 activator. Stimulates human TRPA1 channels in vitro and enables repeated photoactivation of motor behaviors in wild-type zebrafish (EC50 = 2 μM) and mice, in vivo.

Technical Data

M.Wt:
315.41
Formula:
C15H13N3OS2
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
348575-88-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Photochemical activation of TRPA1 channels in neurons and animals.
    Kokel et al.
    Nat.Chem.Biol., 2013;9:257

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

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Citations for Optovin

The citations listed below are publications that use Tocris products. Selected citations for Optovin include:

3 Citations: Showing 1 - 3

  1. Social isolation modulates appetite and avoidance behavior via a common oxytocinergic circuit in larval zebrafish.
    Authors: Sandy Et al.
    Nat Commun  2022;13:2573
  2. Enteroendocrine cells sense bacterial tryptophan catabolites to activate enteric and vagal neuronal pathways.
    Authors: Jon Et al.
    Cell Host Microbe  2021;29:179-196.e9
  3. Zebrafish oxytocin neurons drive nocifensive behavior via brainstem premotor targets.
    Authors: James A Et al.
    Nat Neurosci  2019;22:1477-1492

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