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PDD 00017272

Catalog #: 7006
1 Citation Datasheet / COA / SDS
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7006/1
7006/10
PDD 00017272 | CAS No. 1945950-20-8 | PARG Inhibitors
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Description: Potent PARG inhibitor

Chemical Name: 1-[(2,4-Dimethyl-5-thiazolyl)methyl]-1,2,3,4-tetrahydro-N-(1-methylcyclopropyl)-3-[(2-methyl-5-thiazolyl)methyl]-2,4-dioxo-6-quinazolinesulfonamide

Purity: ≥98%

Product Details
Citations (1)
Reviews
Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

PDD 00017272 is a potent poly (ADP ribose) glycohydrolase (PARG) inhibitor (IC50 values are 4.8 nM in biochemical assay and 9.2 nM in cell based assay).

Technical Data

M.Wt:
531.66
Formula:
C23H25N5O4S3
Solubility:
Soluble to 20 mM in DMSO with gentle warming
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
1945950-20-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under license from Cancer Research Technology Ltd (Ximbio).

Product Datasheets

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Citation for PDD 00017272

The citations listed below are publications that use Tocris products. Selected citations for PDD 00017272 include:

1 Citation: Showing 1 - 1

  1. Transcription-replication conflicts underlie sensitivity to PARP inhibitors.
    Authors: Petropoulos Et al.
    Nature  2024;628:433

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