Pentostatin

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. Hypoxia-induced deoxycytidine kinase expression contributes to apoptosis in chronic lung disease.
   Weng T, Karmouty-Quintana H, Garcia-Morales L, Molina J, Pedroza M, Bunge R, Bruckner B, Loebe M, Seethamraju H, Blackburn M
   FASEB J, 2013;27(5):2013-26.
2. Crosstalk between the equilibrative nucleoside transporter ENT2 and alveolar Adora2b adenosine receptors dampens acute lung injury.
   Eckle T, Hughes K, Ehrentraut H, Brodsky K, Rosenberger P, Choi D, Ravid K, Weng T, Xia Y, Blackburn M, Eltzschig H
   FASEB J, 2013;27(8):3078-89.
3. Characterization of the Drosophila adenosine receptor: the effect of adenosine analogs on cAMP signaling in Drosophila cells and their utility for in vivo experiments.
   Kucerova L, Broz V, Fleischmannova J, Santruckova E, Sidorov R, Dolezal V, Zurovec M
   J. Neurochem., 2012;121(3):383-95.
4. Pentostatin: future directions.
   Klohs and Kraker
   Pharmacol.Rev., 1992;44:459
5. Purine nucleoside analogues and combination therapies in B-cell chronic lymphocytic leukemia: dawn of a new era.
   Nabhan et al.
   Leukemia Res., 2004;28:429

Product Datasheets