Phalloidin
Purity: ≥90%
Biological Activity
Phalloidin is a promotes actin polymerization. Decreases dissociation rate constant for actin subunits from filament ends; lowers critical concentration for polymerization.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Phalloidin perturbs the interaction of human non-muscle myosin isoforms 2A and 2C1 with F-actin.
Diensthuber et al.
FEBS Lett., 2011;585:767 -
Effects of cytochalasin and phalloidin on actin.
Cooper
J.Cell Biol., 1987;105:1473 -
Phalloidin enhances actin assembly by preventing monomer dissociation.
Coluccio and Tilney
J.Cell Biol., 1984;99:529 -
Phalloidin-induced actin polymerization in the cytoplasm of cultured cells interferes with cell locomotion and growth.
Wehland et al.
Proc.Natl.Acad.Sci.USA, 1977;74:5613
Product Datasheets
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Citation for Phalloidin
The citations listed below are publications that use Tocris products. Selected citations for Phalloidin include:
1 Citation: Showing 1 - 1
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Dopamine D4 receptors regulate AMPA receptor trafficking and glutamatergic transmission in GABAergic interneurons of prefrontal cortex.
Authors: Zhen Et al.
J Neurosci 2009;29:550-62
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