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Phenyl-glutarimide 4'-piperazine

Catalog #: 7729 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
7729/100
Phenyl-glutarimide 4'-piperazine | CAS No. 2902651-89-0 | Degrader Building Blocks
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Description: Piperazine-functionalized cereblon ligand for PROTAC development

Chemical Name: 3-[4-(1-Piperazinyl)phenyl]-2,6-piperidinedione dihydrochloride

Purity: ≥95%

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Biological Activity

Phenyl-glutarimide 4'-piperazine is a piperazine-functionalized cereblon ligand that can be used for PROTAC® Degrader development. The compound can be used to develop PG-PROTACs that exhibit improved stability to hydrolysis and potency compared with PROTACs synthesized using IMiD (immunomodulatory imide drug) analogs.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data

M.Wt:
346.25
Formula:
C15H19N3O2.2HCl
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
2902651-89-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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