Home / ERK1/ERK2 / Phospho-ERK1 (T202/Y204)/ERK2 (T185/Y187) Surveyor IC

Phospho-ERK1 (T202/Y204)/ERK2 (T185/Y187) Surveyor IC

Catalog #: SUV1018B
3 Citations Datasheet / COA / SDS

Discontinued Product

SUV1018B has been discontinued.
View all ERK1/ERK2 products.
Product Details
Citations (3)
FAQs
Reviews
Summary Product Datasheets Background

Phospho-ERK1 (T202/Y204)/ERK2 (T185/Y187) Surveyor IC Summary

Specifications

Source
N/A
Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Species
Human Mouse Rat

Product Datasheets

You must select a language.

x
Product Datasheet
COA
SDS

Background: ERK1/ERK2

ERK1 and ERK2 (also known as MAPK3 and MAPK1) are 44 and 42 kDa Ser/Thr kinases, respectively. They are part of the Ras-Raf-ERK signal transduction cascade often found downstream of growth factor receptor activation. ERK1 and ERK2 were initially isolated and cloned as kinases activated in response to insulin and NGF. They are expressed in most, if not all, mammalian tissues. Dual threonine and tyrosine phosphorylation activate both ERKs, at Thr202/Tyr204 for human ERK1 and Thr185/Tyr187 for human ERK2.

ERK5, also known as Big Mitogen-activated Protein Kinase 1 (BMK1) and MAPK7, is activated by several mechanisms, including receptor tyrosine kinases, G protein-coupled receptors, and osmotic stress. Like ERK1 and ERK2, ERK5 contains the conserved Thr-Glu-Tyr activation motif in its activation loop. Unlike these ERKs, however, ERK5 contains a unique C-terminal domain that regulates its activation and nuclear translocation.

Long Name
Extracellular Signal-regulated Kinase 1/2
Alternate Names
ERK1; ERK-1; ERK1/ERK2; ERT2; Extracellular signal-regulated kinase 1; extracellular signal-related kinase 1; HS44KDAP; HUMKER1A; Insulin-stimulated MAP2 kinase; MAPK 1; Microtubule-associated protein 2 kinase; mitogen-activated protein kinase 3; p44erk1; p44-ERK1; p44mapk; p44-MAPK; PRKM3

Citations for Phospho-ERK1 (T202/Y204)/ERK2 (T185/Y187) Surveyor IC

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

3 Citations: Showing 1 - 3
Filter your results:

Filter by:

  1. Lysophosphatidic acid signals through multiple receptors in osteoclasts to elevate cytosolic calcium concentration, evoke retraction, and promote cell survival.
    Authors: Lapierre DM, Tanabe N, Pereverzev A
    J. Biol. Chem., 2010-06-15;285(33):25792-801.  2010-06-15
  2. Discovery of a novel class of targeted kinase inhibitors that blocks protein kinase C signaling and ameliorates retinal vascular leakage in a diabetic rat model.
    Authors: Grant S, Tran P, Zhang Q, Zou A, Dinh D, Jensen J, Zhou S, Kang X, Zachwieja J, Lippincott J, Liu K, Johnson SL, Scales S, Yin C, Nukui S, Stoner C, Prasanna G, Lafontaine J, Wells P, Li H
    Eur. J. Pharmacol., 2009-10-20;627(1):16-25.  2009-10-20
  3. EF domains are sufficient for nongenomic mineralocorticoid receptor actions.
    Authors: Grossmann C, Freudinger R, Mildenberger S, Husse B, Gekle M
    J. Biol. Chem., 2008-01-08;283(11):7109-16.  2008-01-08

FAQs

No product specific FAQs exist for this product, however you may

View all ELISA FAQs

Reviews for Phospho-ERK1 (T202/Y204)/ERK2 (T185/Y187) Surveyor IC

There are currently no reviews for this product. Be the first to review Phospho-ERK1 (T202/Y204)/ERK2 (T185/Y187) Surveyor IC and earn rewards!

Have you used Phospho-ERK1 (T202/Y204)/ERK2 (T185/Y187) Surveyor IC?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review