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Physostigmine hemisulfate

Catalog #: 0622
6 Citations Datasheet / COA / SDS
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0622/10
Physostigmine hemisulfate | CAS No. 64-47-1 | Cholinesterase Inhibitors
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Description: Cholinesterase inhibitor

Chemical Name: (3aS)-cis-1,2,3,3a,8,8a-Hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indol-5-ol methylcarbamate hemisulfate

Purity: ≥98%

Product Details
Citations (6)
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Biological Activity

Physostigmine hemisulfate is a cholinesterase inhibitor.

Technical Data

M.Wt:
324.39
Formula:
C15H21N3O2.½H2SO4
Solubility:
Soluble to 100 mM in water
Purity:
≥98%
Storage:
Desiccate at RT
CAS No:
64-47-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
    Fox JT, Sakamuru S, Huang R
    Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
  2. Anticholinesterases: medical applications of neurochemical principles.
    Millard and Broomfield
    J.Neurochem, 1995;64:1909

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Citations for Physostigmine hemisulfate

The citations listed below are publications that use Tocris products. Selected citations for Physostigmine hemisulfate include:

6 Citations: Showing 1 - 6

  1. Impact of Altered Cholinergic Tones on the Neurovascular Coupling Response to Whisker Stimulation.
    Authors: Lecrux Et al.
    J Neurosci  2017;37:1518
  2. Cholinergic and ghrelinergic receptors and KCNQ channels in the medial PFC regulate the expression of palatability.
    Authors: Parent Et al.
    Proc Natl Acad Sci U S A  2015;9:284
  3. Muscarinic regulation of DA and glutamate transmission in the nucleus accumbens.
    Authors: Shin Et al.
    Front Neurosci  2015;112:8124
  4. Energy substrates that fuel fast neuronal network oscillations.
    Authors: Galow Et al.
    J Neurosci  2014;8:398
  5. Oxygen consumption rates during three different neuronal activity states in the hippocampal CA3 network.
    Authors: Huchzermeyer Et al.
    J Cereb Blood Flow Metab  2013;33:263
  6. Input-specific plasticity at excitatory synapses mediated by endocannabinoids in the dentate gyrus.
    Authors: Chiu and Castillo
    Neuropharmacology  2008;54:68

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