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PMX 53c

Catalog #: 5697 Datasheet / COA / SDS

Discontinued Product

5697 has been discontinued.
View all Complement Signaling inhibitors products.
PMX 53c
1 Image
Description: Negative control for PMX 53 (Cat. No. 5473)

Purity: ≥95%

Product Details
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Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

PMX 53c is a negative control for PMX 53.

Active Analog also available.

Technical Data

M.Wt:
780.96
Formula:
C39H60N10O7
Sequence:
FXPXAR

(Modifications: Phe-1 = N-terminal Ac, X-2 = Orn, X-4 = D-Cha, Arg-6 = D-Arg, Lactam bridge: Orn-2 to Arg-6)

Solubility:
Soluble to 2 mg/ml in water
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
827600-15-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Other Product-Specific Information:

Background References

  1. PMX-53 as a dual CD88 antagonist and an agonist for Mas-related gene 2 (MrgX2) in human mast cells.
    Subramanian et al.
    Mol.Pharmacol., 2011;79:1005
  2. Mechanisms Driving Neutrophil-Induced T-cell Immunoparalysis in Ovarian Cancer
    TR Emmons, T Giridharan, KL Singel, ANH Khan, J Ricciuti, K Howard, SL Silva-Del, IL Debreceni, CEM Aarts, MC Brouwer, S Suzuki, TW Kuijpers, I Jongerius, LH Allen, VP Ferreira, A Schubart, H Sellner, J Eder, SM Holland, S Ram, JA Lederer, KH Eng, KB Moysich, K Odunsi, MB Yaffe, E Zsiros, BH Segal
    Cancer Immunology Research, 2021;9(7):790-810.

Product Datasheets

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