Quinelorane hydrochloride

Catalog #: 1519
1 Citation Datasheet / COA / SDS

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1519/10

Quinelorane hydrochloride | CAS No. 97548-97-5 | Non-selective Dopamine Receptor Agonists

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Description: D2 and D3 agonist

Alternative Names: LY 163502

Chemical Name: (5aR,9aR)-5,5a,6,7,8,9,9a,10-Octahydro-6-propylpyrido[2,3-g]quinazolin-2-amine dihydrochloride

Purity: ≥99%

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Product Details

Citations (1)

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Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

Quinelorane hydrochloride is a dopamine D₂ and D₃ receptor agonist; K_i values are 5.7 and 3.4 nM respectively.

Technical Data

M.Wt:

319.27

Formula:

C₁₄H₂₂N₄.2HCl

Solubility:

Soluble to 25 mM in water

Purity:

≥99%

Storage:

Desiccate at RT

CAS No:

97548-97-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:

Sold with the permission of Eli Lilly and Company

Background References

Preclinical studies on quinelorane, a potent and highly selective D₂-DArgic agonist.
Foreman et al.
J.Pharmacol.Exp.Ther., 1989;250:227
Effects of the selective DArgic D₂ agonist quinelorane on the activity of DArgic and noradrenergic neurons projecting to the diencephalon of the rat.
Eaton et al.
J.Pharmacol.Exp.Ther., 1994;268:645
Comparison of D₂ and D₃ DA receptor affinity of DArgic compounds in the rat brain.
Flietstra and Levant
Life Sci., 1998;62:1825

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Citation for Quinelorane hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for Quinelorane hydrochloride include:

1 Citation: Showing 1 - 1

Gene-environment interactions affect long-term depression (LTD) through changes in DA receptor affinity in Snap25 deficient mice.
Authors: Baca Et al.
Brain Res 2013;1532:85

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