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Quinidine

Catalog #: 4108
5 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4108/50
Quinidine | CAS No. 56-54-2 | Ion Channel Modulators
1 Image
Description: Blocks sodium and potassium channels

Chemical Name: (S)-(6-Methoxyquinolin-4-yl)((2R,4S,8R)- 8-vinylquinuclidin-2-yl)methanol hydrochloride

Product Details
Citations (5)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Quinidine is a class IA antiarrythmic; reduces both Na+ and K+ channel currents, including INa, IKr and IKs. Prolongs QT and induces torsade de pointes (TdP).

Technical Data

M.Wt:
324.42
Formula:
C20H24N2O2
Solubility:
Soluble to 100 mM in DMSO and to 25 mM in ethanol
Storage:
Store at -20°C
CAS No:
56-54-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Reconstitution Calculator
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Reconstitution Calculator

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Citations for Quinidine

The citations listed below are publications that use Tocris products. Selected citations for Quinidine include:

5 Citations: Showing 1 - 5

  1. Global feather orientations changed by electric current.
    Authors: Ting-Xin Et al.
    iScience  2021;24:102671
  2. Downregulation of miR-7116-5p in microglia by MPP+ sensitizes TNF-α production to induce dopaminergic neuron damage.
    Authors: He Et al.
    Glia  2017;65:1251
  3. GABAB receptors in neocortical and hippocampal pyramidal neurons are coupled to different potassium channels.
    Authors: Jean-Didier Et al.
    Eur J Neurosci  2017;46:2859-2866
  4. Targeting cancer metabolism by simultaneously disrupting parallel nutrient access pathways.
    Authors: Kim Et al.
    J Clin Invest  2016;126:4088
  5. Electrophysiological characterization and computational models of HVC neurons in the zebra finch.
    Authors: Richard Et al.
    J Neurophysiol  2013;110:1227-45

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