Quipazine dimaleate
Chemical Name: 2-(1-Piperazinyl)quinoline dimaleate
Purity: ≥99%
Biological Activity
Quipazine dimaleate is a selective 5-HT3 receptor agonist. Also displays antagonist activity at peripheral 5-HT3 receptors. [3H]-Quipazine labels 5-HT3 sites in the cortical membranes.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
Fox JT, Sakamuru S, Huang R
Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8. -
Pharmacological characterization of 5-hydroxytryptamine-induced depolarization of the rat isolated vagus nerve.
Ireland and Tyers
Br.J.Pharmacol., 1987;90:229 -
[3H]Quipazine labels 5-HT3 recognition sites in rat cortical membranes.
Peroutka and Hamik
Eur.J.Pharmacol., 1988;148:297 -
Characteristics of 5-HT3 binding sites in NG108-15, NCB-20 neuroblastoma cells and rat cerebral cortex using [3H]-quipazine and [3H]-GR65630 binding.
Sharif et al.
Br.J.Pharmacol., 1991;102:919
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Citation for Quipazine dimaleate
The citations listed below are publications that use Tocris products. Selected citations for Quipazine dimaleate include:
1 Citation: Showing 1 - 1
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Differential regulation of MeCP2 phosphorylation in the CNS by DA and serotonin.
Authors: Hutchinson Et al.
Br J Pharmacol 2012;37:321
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