(R)-3,4-DCPG
Chemical Name: (R)-3,4-Dicarboxyphenylglycine
Purity: ≥96%
Biological Activity
(R)-3,4-DCPG is a AMPA receptor antagonist with weak activity at NMDA receptors and little activity at kainate receptors.Racemate and S-enantiomer also available.
Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
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Anticonvulsant activity of 3,4-dicarboxyphenylglycines in DBA/2 mice.
Moldrich et al.
Neuropharmacology, 2001;40:732 -
Dicarboxyphenylglycines antagonize AMPA- but not kainate-induced depolarizations in neonatal rat motoneurones.
Thomas et al.
Eur.J.Pharmacol., 1997;338:111
Product Datasheets
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Citation for (R)-3,4-DCPG
The citations listed below are publications that use Tocris products. Selected citations for (R)-3,4-DCPG include:
1 Citation: Showing 1 - 1
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Structure based model for the prediction of phospholipidosis induction potential of small molecules.
Authors: Sun Et al.
J Chem Inf Model 2012;52:1798
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