Rasagiline mesylate
Chemical Name: (1R)-2,3-Dihydro-N-2-propynyl-1H-inden-1-amine methanesulfonate
Purity: ≥99%
Biological Activity
Rasagiline mesylate is a selective irreversible MAO-B inhibitor. Displays antiParkinsonian activity; exhibits neuroprotective and antiapoptotic activity against several neurotoxins in cell culture.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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The anti-parkinson drug, rasagiline, prevents apoptotic DNA damage induced by peroxynitrite in human DArgic neuroblastoma SH-SY5Y cells.
Maruyama et al.
J.Neural Transm., 2002;109:467 -
Pharmacological properties of the anti-Parkinson drug rasagiline; modification of endogenous brain amines, rese. reversal, serotonergic and DArgic behaviours.
Finberg and Youdim
Neuropharmacology, 2002;43:1110
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