Rauwolscine hydrochloride

Biological Activity

Diastereomer also avilable.

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Background References

1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
   Fox JT, Sakamuru S, Huang R
   Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
2. Partial agonist properties of rauwolscine and yohimbine for the inhibition of adenylyl cyclase by recombinant human 5-HT_1A receptors.
   Arthur et al.
   Biochem.Pharmacol., 1993;45:2337
3. α and β-adrenoceptors: from the gene to the clinic. 1. Molecular biology and adrenoceptor subclassification.
   Heible et al.
   J.Med.Chem., 1995;38:3415
4. β- and γ-Adrenoceptors: from the gene to the clinic. 1. Molecular biology and adrenoceptor subclassification.
   Hieble et al.
   J.Med.Chem., 1995;38:3415
5. [3H]RS79948-197 binding to human, rat, guinea pig and pig α_2A-, α_2B-, and α_2C-adrenoceptors. Comparison with MK912, RX821002, rauwolscine and yohimbine.
   Uhlen et al.
   Eur.J.Pharmacol., 1998;343:93

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