RCM 1

Catalog #: 6845 Datasheet / COA / SDS

Discontinued Product

6845 has been discontinued.
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RCM 1 | CAS No. 339163-65-4 | FoxM1
1 Image
Description: FOXM1 inhibitor

Chemical Name: 2-[[2-Oxo-2-(2-thienyl)ethyl]thio]-4,6-di-2-thienyl-3-pyridinecarbonitrile

Purity: ≥98%

Product Details
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Biological Activity

RCM 1 is a forkhead box M1 (FOXM1) transcription factor inhibitor (IC50 = 0.72 μM). Inhibits expression of FOXM1 target genes. Induces FOXM1 protein degradation in vitro. Reduces airway resistance, increases lung compliance and decreases proinflammatory cytokine production in allergen-exposed mice.

Technical Data

M.Wt:
424.58
Formula:
C20H12N2OS4
Solubility:
Soluble to 20 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
339163-65-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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