Home / FGF-9 / Recombinant Human FGF-9 Protein

Recombinant Human FGF-9 Protein

Catalog #: 273-F9
47 Citations Datasheet / COA / SDS
Sf21-Expressed

Carrier Free

Catalog # Availability Size / Price Qty
273-F9-025/CF

With Carrier

Catalog # Availability Size / Price Qty
273-F9-025
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Graph showing dose-dependent bioactivity of Human FGF-9 protein
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Product Details
Citations (47)
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Summary Product Datasheets Carrier Free Data Images Reconstitution Calculator Background Related Research Areas

Recombinant Human FGF-9 Protein Summary

Product Specifications

Purity
>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Endotoxin Level
<1.0 EU per 1 μg of the protein by the LAL method.
Activity
Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. Rubin, J.S. et al. (1991) Proc. Natl. Acad. Sci. USA 88:415. The ED50 for this effect is 1-5 ng/mL.
Source
Spodoptera frugiperda, Sf 21 (baculovirus)-derived human FGF-9 protein
Met1-Ser208 & Ala2-Ser208
Accession #
P31371
N-terminal Sequence
Analysis
Met1 & Ala2
Predicted Molecular Mass
23 kDa
SDS-PAGE
Multiple bands between 22-29 kDa, reducing conditions

Product Datasheets

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273-F9 (with carrier)

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273-F9/CF (carrier free)

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COA
SDS

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

273-F9

Formulation Lyophilized from a 0.2 μm filtered solution in MOPS, Na2SO4 and EDTA with BSA as a carrier protein.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 3 months, 2 to 8 °C under sterile conditions after reconstitution.

273-F9/CF

Formulation Lyophilized from a 0.2 μm filtered solution in MOPS, Na2SO4 and EDTA.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 3 months, 2 to 8 °C under sterile conditions after reconstitution.

Scientific Data

Bioactivity Graph showing dose-dependent bioactivity of Human FGF-9 protein View Larger

Recombinant human FGF-9 (273-F9) induces proliferation in the Balb/3T3 mouse embryonic fibroblast cell line. The ED50 for this effect is 1-5 ng/mL.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: FGF-9

FGF-9 (fibroblast growth factor-9), also called HBGF-9 (heparin-binding growth factor-9) and GAF (glia-activating factor), is an approximately 26 kDa secreted glycoprotein of the FGF family (1-3). FGFs exhibit heparin-dependent regulation of cell proliferation, differentiation, and function, and are characterized by a core heparin-binding FGF domain of approximately 120 amino acids (aa) that exhibits a beta -trefoil structure (1). FGF-9, -16 and -20 form a subfamily that shares 65-71% aa sequence identity, binds FGF R3 (IIIb), and are efficiently secreted despite having an uncleavable, bipartite signal sequence (1-3). Secreted human FGF-9 is a
205-207 aa protein that lacks the N-terminal 1-3 aa and shares 98% sequence identity with mouse, rat, equine, porcine and bovine FGF-9. In addition to FGF R3 (IIIb), FGF-9 binding to the IIIc splice forms of FGF R1, R2 and R3 are variably reported (3-5). An unusual constitutive dimerization of FGF-9 buries receptor interaction sites which lowers its activity, and increases heparin affinity which inhibits diffusion (4-6). A spontaneous mouse mutant, Eks, interferes with dimerization, resulting monomeric, diffusible FGF-9 that causes elbow and knee synostoses (joint fusions) due to FGF-9 misexpression in developing joints (6). In humans, FGF-9 mutations that lower receptor binding cause multiple synostoses syndrome (SYNS) (7). Expression in brain and kidney are reported in the adult rat (2, 8). In the mouse embryo the location and timing of FGF-9 expression affects development of the skeleton, cerebellum, lungs, heart, vasculature, digestive tract, and testes (1, 6-11). Deletion of mouse FGF-9 is lethal at birth due to lung hypoplasia, and causes rhizomelia, or shortening of the proximal skeleton (1, 10, 11). Altered FGF-9 expression or function is reported in human colon, endometrial, and ovarian cancers, correlating with progression, invasiveness, and survival (12-15).

References
  1. Itoh, N. and D.M. Ornitz (2008) Dev. Dyn. 237:18.
  2. Miyamoto, M. et al. (1993) Mol. Cell. Biol. 13:4251.
  3. Santos-Ocampo, S. et al. (1996) J. Biol. Chem. 271:1726.
  4. Mohammadi, M. et al. (2005) Cytokine Growth Factor Rev. 16:107.
  5. Plotnikov, A.N. et al. (2001) J. Biol. Chem. 276:4322.
  6. Harada, M. et al. (2009) Nat. Genet. 41:289.
  7. Wu, X.L. et al. (2009) Am. J. Hum. Genet. 85:53.
  8. Colvin, J.S. et al. (1999) Dev. Dyn. 216:72.
  9. Lin, Y. et al. (2009) Dev. Biol. 329:44.
  10. Hung, I.H. et al. (2007) Dev. Biol. 307:300.
  11. Colvin, J.S. et al. (2001) Dev. Dyn 128:2095.
  12. Krejci, P. et al. (2009) Hum. Mutat. 30:1245.
  13. Leushacke, M. et al. (2011) PLoS ONE 6:e23381.
  14. Hendrix, N.D. et al. (2006) Cancer Res. 66:1354.
  15. Abdel-Rahman, W.M. et al. (2008) Hum. Mutat. 29:390.
Long Name
Fibroblast Growth Factor 9
Entrez Gene IDs
2254 (Human); 14180 (Mouse)
Alternate Names
FGF9; FGF-9; fibroblast growth factor 9 (glia-activating factor); Fibroblast growth factor 9; GAF; glia-activating factor; HBFG-9; HBGF-9; Heparin-binding growth factor 9; MGC119914; MGC119915; SYNS3

Citations for Recombinant Human FGF-9 Protein

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

47 Citations: Showing 1 - 10
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  1. Stepwise developmental mimicry generates proximal-biased kidney organoids
    Authors: Schnell, J;Miao, Z;Achieng, M;Fausto, CC;Wang, V;Kuyper, F;Thornton, ME;Grubbs, B;Kim, J;Lindström, NO;
    bioRxiv : the preprint server for biology
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  2. NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo
    Authors: Namoto, K;Baader, C;Orsini, V;Landshammer, A;Breuer, E;Dinh, KT;Ungricht, R;Pikiolek, M;Laurent, S;Lu, B;Aebi, A;Schönberger, K;Vangrevelinghe, E;Evrova, O;Sun, T;Annunziato, S;Lachal, J;Redmond, E;Wang, L;Wetzel, K;Capodieci, P;Turner, J;Schutzius, G;Unterreiner, V;Trunzer, M;Buschmann, N;Behnke, D;Machauer, R;Scheufler, C;Parker, CN;Ferro, M;Grevot, A;Beyerbach, A;Lu, WY;Forbes, SJ;Wagner, J;Bouwmeester, T;Liu, J;Sohal, B;Sahambi, S;Greenbaum, LE;Lohmann, F;Hoppe, P;Cong, F;Sailer, AW;Ruffner, H;Glatthar, R;Humar, B;Clavien, PA;Dill, MT;George, E;Maibaum, J;Liberali, P;Tchorz, JS;
    Cell stem cell
    Species: Human
    Sample Types: Organoid
    Applications: Bioassay
  3. Ligand bias underlies differential signaling of multiple FGFs via FGFR1
    Authors: Karl, K;Del Piccolo, N;Light, T;Roy, T;Deduja, P;Ursachi, VC;Fafilek, B;Krejci, P;Hristova, K;
    eLife
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  4. Highly-parallel production of designer organoids by mosaic patterning of progenitors
    Authors: Porter, CM;Qian, GC;Grindel, SH;Hughes, AJ;
    bioRxiv : the preprint server for biology
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  5. Directed differentiation of ureteric bud and collecting duct organoids from human pluripotent stem cells
    Authors: Shi, M;Fu, P;Bonventre, JV;McCracken, KW;
    Nature protocols
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  6. A single-cell multiomic analysis of kidney organoid differentiation
    Authors: Yoshimura, Y;Muto, Y;Ledru, N;Wu, H;Omachi, K;Miner, JH;Humphreys, BD;
    Proceedings of the National Academy of Sciences of the United States of America
    Species: Human
    Sample Types: Organoids
    Applications: Bioassay
  7. SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids
    Authors: J Jansen, KC Reimer, JS Nagai, FS Varghese, GJ Overheul, M de Beer, R Roverts, D Daviran, LAS Fermin, B Willemsen, M Beukenboom, S Djudjaj, S von Stillf, LE van Eijk, M Mastik, M Bulthuis, WD Dunnen, H van Goor, JL Hillebrand, SH Triana, T Alexandrov, MC Timm, BT van den Be, M van den Br, Q Nlandu, J Heijnert, EMJ Bindels, RM Hoogenboez, F Mooren, C Kuppe, P Miesen, K Grünberg, T Ijzermans, EJ Steenberge, J Czogalla, MF Schreuder, N Sommerdijk, A Akiva, P Boor, VG Puelles, J Floege, TB Huber, COVID Moon, RP van Rij, IG Costa, RK Schneider, B Smeets, R Kramann
    Cell Stem Cell, 2021-12-25;29(2):217-231.e8.
    Species: Human
    Sample Types: Organoids
    Applications: Bioassay
  8. Genome-wide screening in human kidney organoids identifies developmental and disease-related aspects of nephrogenesis
    Authors: R Ungricht, L Guibbal, MC Lasbennes, V Orsini, M Beibel, A Waldt, R Cuttat, W Carbone, A Basler, G Roma, F Nigsch, JS Tchorz, D Hoepfner, PS Hoppe
    Cell Stem Cell, 2021-11-29;0(0):.
    Species: Human
    Sample Types: Organoid
    Applications: Bioassay
  9. A tissue-bioengineering strategy for modeling rare human kidney diseases in vivo
    Authors: JOR Hernandez, X Wang, M Vazquez-Se, M Lopez-Marf, MF Sobral-Rey, A Moran-Horo, M Sundberg, DO Lopez-Cant, CK Probst, GU Ruiz-Espar, K Giannikou, R Abdi, EP Henske, DJ Kwiatkowsk, M Sahin, DR Lemos
    Nature Communications, 2021-11-11;12(1):6496.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  10. The embryonic ontogeny of the gonadal somatic cells in mice and monkeys
    Authors: K Sasaki, A Oguchi, K Cheng, Y Murakawa, I Okamoto, H Ohta, Y Yabuta, C Iwatani, H Tsuchiya, T Yamamoto, Y Seita, M Saitou
    Cell Reports, 2021-05-04;35(5):109075.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  11. Identification of candidate PAX2-regulated genes implicated in human kidney development
    Authors: Y Yamamura, K Furuichi, Y Murakawa, S Hirabayash, M Yoshihara, K Sako, S Kitajima, T Toyama, Y Iwata, N Sakai, K Hosomichi, PM Murphy, A Tajima, K Okita, K Osafune, S Kaneko, T Wada
    Scientific Reports, 2021-04-27;11(1):9123.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  12. Effects of selected hormones and their combination on progesterone and estradiol production and proliferation of feline granulosa cells cultured in�vitro
    Authors: M Chiara Per, N Bellitto, ERS Maylem, F Caloni, LJ Spicer
    Theriogenology, 2021-03-28;168(0):1-12.
    Species: Feline
    Sample Types: Whole Cells
    Applications: Bioassay
  13. Plasticity of distal nephron epithelia from human kidney organoids enables the induction of ureteric tip and stalk
    Authors: SE Howden, SB Wilson, E Groenewege, L Starks, TA Forbes, KS Tan, JM Vanslambro, EM Holloway, YH Chen, S Jain, JR Spence, MH Little
    Cell Stem Cell, 2020-12-29;0(0):.
    Species: Human
    Sample Types: Transfected Whole Cells
    Applications: Bioassay
  14. Human Pluripotent Stem Cell-Derived Kidney Organoids with Improved Collecting Duct Maturation and Injury Modeling
    Authors: K Uchimura, H Wu, Y Yoshimura, BD Humphreys
    Cell Reports, 2020-12-15;33(11):108514.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  15. An In�Vitro Differentiation Protocol for Human Embryonic Bipotential Gonad and Testis Cell Development
    Authors: IM Knarston, S Pachernegg, G Robevska, I Ghobrial, PX Er, E Georges, M Takasato, AN Combes, A Jørgensen, MH Little, AH Sinclair, KL Ayers
    Stem Cell Reports, 2020-11-19;15(6):1377-1391.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  16. Epigenetic transcriptional reprogramming by WT1 mediates a repair response during podocyte injury
    Authors: S Ettou, YL Jung, T Miyoshi, D Jain, K Hiratsuka, V Schumacher, ME Taglienti, R Morizane, PJ Park, JA Kreidberg
    Sci Adv, 2020-07-24;6(30):eabb5460.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  17. Asynchronous mixing of kidney progenitor cells potentiates nephrogenesis in organoids.
    Authors: Kumar Gupta A, Sarkar P, Wertheim J, Pan X, Carroll T, Oxburgh L
    Commun Biol, 2020-05-11;3(1):231.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  18. Nucleus size and DNA accessibility are linked to the regulation of paraspeckle formation in cellular differentiation
    Authors: M Grosch, S Ittermann, E Rusha, T Greisle, C Ori, DJ Truong, AC O'Neill, A Pertek, GG Westmeyer, M Drukker
    BMC Biol., 2020-04-22;18(1):42.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  19. Upregulation of cancer-associated gene expression in activated fibroblasts in a mouse model of non-alcoholic steatohepatitis
    Authors: M Asakawa, M Itoh, T Suganami, T Sakai, S Kanai, I Shirakawa, X Yuan, T Hatayama, S Shimada, Y Akiyama, K Fujiu, Y Inagaki, I Manabe, S Yamaoka, T Yamada, S Tanaka, Y Ogawa
    Sci Rep, 2019-12-20;9(1):19601.
    Species: Human, Xenograft
    Sample Types: In Vivo, Whole Cells
    Applications: Bioassay, In Vivo
  20. Progestin-induced heart and neural crest derivatives-expressed transcript 2 inhibits angiopoietin 2 via fibroblast growth factor 9 in human endometrial stromal cells
    Authors: H Murata, T Tsuzuki, T Kido, M Kakita-Kob, N Kida, Y Hisamatsu, H Okada
    Reprod Biol, 2019-03-06;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  21. Feather arrays are patterned by interacting signalling and cell density waves
    Authors: WKW Ho, L Freem, D Zhao, KJ Painter, TE Woolley, EA Gaffney, MJ McGrew, A Tzika, MC Milinkovit, P Schneider, A Drusko, F Matthäus, JD Glover, KL Wells, JA Johansson, MG Davey, HM Sang, M Clinton, DJ Headon
    PLoS Biol., 2019-02-21;17(2):e3000132.
    Species: Chicken
    Sample Types: Tissue Explants
    Applications: Bioassay
  22. An in vitro model for studying CNS white matter: functional properties and experimental approaches
    Authors: S Bijland, G Thomson, M Euston, K Michail, K Thümmler, S Mücklisch, CL Crawford, SC Barnett, M McLaughlin, TJ Anderson, C Linington, ER Brown, ER Kalkman, JM Edgar
    F1000Res, 2019-01-29;8(0):117.
    Species: Mouse
    Sample Types: Embryonic Spinal Cord Cells
    Applications: Bioassay
  23. Comparative Analysis and Refinement of Human PSC-Derived Kidney Organoid Differentiation with Single-Cell Transcriptomics
    Authors: H Wu, K Uchimura, EL Donnelly, Y Kirita, SA Morris, BD Humphreys
    Cell Stem Cell, 2018-11-15;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  24. Human Pluripotent Stem Cell-Derived Kidney Model for Nephrotoxicity Studies.
    Authors: Bajaj P, Rodrigues A, Steppan C, Engle S, Mathialagan S, Schroeter T
    Drug Metab Dispos, 2018-08-31;46(11):1703-1711.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  25. Renal Subcapsular Transplantation of PSC-Derived Kidney Organoids Induces Neo-vasculogenesis and Significant Glomerular and Tubular Maturation In�Vivo
    Authors: CW van den Be, L Ritsma, MC Avramut, LE Wiersma, BM van den Be, DG Leuning, E Lievers, M Koning, JM Vanslambro, AJ Koster, SE Howden, M Takasato, MH Little, TJ Rabelink
    Stem Cell Reports, 2018-03-01;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  26. Identification of direct negative crosstalk between the SLIT2 and Bone Morphogenetic Protein-Gremlin signaling pathways
    Authors: KE Tumelty, N Higginson-, X Fan, P Bajaj, KM Knowlton, M Shamashkin, AJ Coyle, W Lu, SP Berasi
    J. Biol. Chem., 2018-01-09;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  27. Transcriptome profiling of bovine ovarian theca cells treated with fibroblast growth factor 9
    Authors: LF Schütz, RE Hurst, NB Schreiber, LJ Spicer
    Domest. Anim. Endocrinol., 2018-01-04;63(0):48-58.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  28. Higher-Order Kidney Organogenesis from Pluripotent Stem Cells
    Authors: A Taguchi, R Nishinakam
    Cell Stem Cell, 2017-11-09;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  29. Transplantation of bioengineered rat lungs recellularized with endothelial and adipose-derived stromal cells
    Authors: R Doi, T Tsuchiya, N Mitsutake, S Nishimura, M Matsuu-Mat, Y Nakazawa, T Ogi, S Akita, H Yukawa, Y Baba, N Yamasaki, K Matsumoto, T Miyazaki, R Kamohara, G Hatachi, H Sengyoku, H Watanabe, T Obata, LE Niklason, T Nagayasu
    Sci Rep, 2017-08-16;7(1):8447.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: Bioassay
  30. Hierarchical patterning modes orchestrate hair follicle morphogenesis
    Authors: JD Glover, KL Wells, F Matthäus, KJ Painter, W Ho, J Riddell, JA Johansson, MJ Ford, CAB Jahoda, V Klika, RL Mort, DJ Headon
    PLoS Biol., 2017-07-11;15(7):e2002117.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  31. Ex vivo analysis of the contribution of FGF10(+) cells to airway smooth muscle cell formation during early lung development
    Authors: E El Agha, V Kheirollah, A Moiseenko, W Seeger, S Bellusci
    Dev. Dyn., 2017-06-01;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  32. Evidence of In�Vitro Preservation of Human Nephrogenesis at the Single-Cell Level
    Authors: N Pode-Shakk, R Gershon, G Tam, D Omer, Y Gnatek, I Kanter, S Oriel, G Katz, O Harari-Ste, T Kalisky, B Dekel
    Stem Cell Reports, 2017-05-25;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  33. Generation of nephron progenitor cells and kidney organoids from human pluripotent stem cells
    Nat Protoc, 2016-12-22;12(1):195-207.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  34. Fibroblast growth factor 9 (FGF9) regulation of cyclin D1 and cyclin-dependent kinase-4 in ovarian granulosa and theca cells of cattle
    Authors: L J Spicer
    Mol. Cell. Endocrinol., 2016-11-03;0(0):.
    Species: Bovine
    Sample Types: Whole Cells
    Applications: Bioassay
  35. NOD2 up-regulates TLR2-mediated IL-23p19 expression via NF-?B subunit c-Rel in Paneth cell-like cells
    Authors: G Tan, E Liang, K Liao, F Deng, W Zhang, Y Chen, J Xu, F Zhi
    Oncotarget, 2016-09-27;7(39):63651-63660.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  36. Fibroblast Growth Factor 9 Imparts Hierarchy and Vasoreactivity to the Microcirculation of Renal Tumors and Suppresses Metastases.
    Authors: Yin H, Frontini M, Arpino J, Nong Z, O'Neil C, Xu Y, Balint B, Ward A, Chakrabarti S, Ellis C, Gros R, Pickering J
    J Biol Chem, 2015-07-16;290(36):22127-42.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  37. FGF9 from cancer-associated fibroblasts is a possible mediator of invasion and anti-apoptosis of gastric cancer cells.
    Authors: Sun C, Fukui H, Hara K, Zhang X, Kitayama Y, Eda H, Tomita T, Oshima T, Kikuchi S, Watari J, Sasako M, Miwa H
    BMC Cancer, 2015-04-30;15(0):333.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  38. FGF/FGFR2 signaling regulates the generation and correct positioning of Bergmann glia cells in the developing mouse cerebellum.
    Authors: Meier F, Giesert F, Delic S, Faus-Kessler T, Matheus F, Simeone A, Holter S, Kuhn R, Weisenhorn D, Wurst W, Prakash N
    PLoS ONE, 2014-07-01;9(7):e101124.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  39. Rapid and efficient differentiation of human pluripotent stem cells into intermediate mesoderm that forms tubules expressing kidney proximal tubular markers.
    Authors: Lam A, Freedman B, Morizane R, Lerou P, Valerius M, Bonventre J
    J Am Soc Nephrol, 2013-12-19;25(6):1211-25.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  40. Redefining the in vivo origin of metanephric nephron progenitors enables generation of complex kidney structures from pluripotent stem cells.
    Authors: Taguchi A, Kaku Y, Ohmori T, Sharmin S, Ogawa M, Sasaki H, Nishinakamura R
    Cell Stem Cell, 2013-12-12;14(1):53-67.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  41. Relationship between the localization of fibroblast growth factor 9 in prostate cancer cells and postoperative recurrence.
    Authors: Teishima J, Shoji K, Hayashi T
    Prostate Cancer Prostatic Dis., 2011-10-18;15(1):8-14.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  42. Fibroblast growth factor 9 delivery during angiogenesis produces durable, vasoresponsive microvessels wrapped by smooth muscle cells.
    Authors: Frontini MJ, Nong Z, Gros R, Drangova M, O'Neil C, Rahman MN, Akawi O, Yin H, Ellis CG, Pickering JG
    Nat. Biotechnol., 2011-04-17;29(5):421-7.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  43. Altered splicing of FGFR1 is associated with high tumor grade and stage and leads to increased sensitivity to FGF1 in bladder cancer.
    Authors: Tomlinson DC, Knowles MA
    Am. J. Pathol., 2010-10-01;177(5):2379-86.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  44. FGF2 posttranscriptionally down-regulates expression of SDF1 in bone marrow stromal cells through FGFR1 IIIc.
    Authors: Nakayama T, Mutsuga N, Tosato G
    Blood, 2006-10-31;109(4):1363-72.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  45. Fibroblast growth factor 9 has oncogenic activity and is a downstream target of Wnt signaling in ovarian endometrioid adenocarcinomas.
    Authors: Hendrix ND, Wu R, Kuick R, Schwartz DR, Fearon ER, Cho KR
    Cancer Res., 2006-02-01;66(3):1354-62.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  46. Expression and possible function of fibroblast growth factor 9 (FGF9) and its cognate receptors FGFR2 and FGFR3 in postnatal and adult retina.
    Authors: Cinaroglu A, Ozmen Y, Ozdemir A, Ozcan F, Ergorul C, Cayirlioglu P, Hicks D, Bugra K
    J. Neurosci. Res., 2005-02-01;79(3):329-39.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  47. Fgf9 induces proliferation and nuclear localization of FGFR2 in Sertoli precursors during male sex determination.
    Authors: Schmahl J, Kim Y, Colvin JS, Ornitz DM, Capel B
    Development, 2004-06-30;131(15):3627-36.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay

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