Recombinant Human ICAM-1/CD54 Fc Chimera Protein, CF
Recombinant Human ICAM-1/CD54 Fc Chimera Protein, CF Summary
Product Specifications
Optimal dilutions should be determined by each laboratory for each application.
Human ICAM-1 Gln28-Glu480 Accession # CAA30051 |
IEGRMD | Human IgG1 (Pro100-Lys330) |
N-terminus | C-terminus | |
Analysis
Product Datasheets
Carrier Free
CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.
In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.
720-IC
Formulation | Lyophilized from a 0.2 μm filtered solution in PBS. |
Reconstitution | Reconstitute at 400 μg/mL in sterile PBS. |
Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
Stability & Storage: | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
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Scientific Data
1 μg/lane of Recombinant Human ICAM-1/CD54 Fc Chimera was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by silver staining, showing bands at 110 kDa and 190 kDa, respectively.
Reconstitution Calculator
Background: ICAM-1/CD54
Intercellular Adhesion Molecule-1 (ICAM-1, CD54) binds the leukocyte integrins LFA-1 and Mac-1. ICAM-1 expression is weak on leukocytes, epithelial and resting endothelial cells, as well as some other cell types, but expression can be stimulated by IFN-gamma, TNF-alpha, IL-1 beta and LPS.
Soluble ICAM-1 is found in a biologically active form in serum, probably as a result of proteolytic cleavage from the cell surface, and is elevated in patients with various inflammatory syndromes such as septic shock, LAD, cancer and transplantation.
Citations for Recombinant Human ICAM-1/CD54 Fc Chimera Protein, CF
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 10
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Chronic stimulation desensitizes ?2-adrenergic receptor responses in natural killer cells
Authors: Jürgens, M;Claus, M;Wingert, S;Niemann, JA;Picard, LK;Hennes, E;Haasler, I;Hellwig, B;Overbeck, N;Reinders, J;Rahnenführer, J;Schedel, M;Capellino, S;Watzl, C;
European journal of immunology
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Dissecting the Therapeutic Mechanisms of Sphingosine-1-Phosphate Receptor Agonism during Ischaemia and Reperfusion
Authors: Wilkins, GC;Gilmour, J;Giannoudaki, E;Kirby, JA;Sheerin, NS;Ali, S;
International journal of molecular sciences
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
An isoform of the giant protein titin is a master regulator of human T lymphocyte trafficking
Authors: Toffali, L;D'Ulivo, B;Giagulli, C;Montresor, A;Zenaro, E;Delledonne, M;Rossato, M;Iadarola, B;Sbarbati, A;Bernardi, P;Angelini, G;Rossi, B;Lopez, N;Linke, WA;Unger, A;Di Silvestre, D;Benazzi, L;De Palma, A;Motta, S;Constantin, G;Mauri, P;Laudanna, C;
Cell reports
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Asymmetric cell division safeguards memory CD8 T�cell development
Authors: Gr�bnitz, F;Stark, D;Shlesinger, D;Petkidis, A;Borsa, M;Yermanos, A;Carr, A;Barandun, N;Wehling, A;Balaz, M;Schroeder, T;Oxenius, A;
Cell reports
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
A20 and the non-canonical NF-kappaB pathway are key regulators of neutrophil recruitment during fetal ontogeny
Authors: I Rohwedder, LM Wackerbart, K Heinig, A Ballweg, J Altstätter, M Ripphahn, C Nussbaum, M Salvermose, S Bierschenk, T Straub, M Gunzer, M Schmidt-Su, T Kolben, C Schulz, A Ma, B Walzog, M Heinig, M Sperandio
JCI Insight, 2023-02-22;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
beta2-Integrin Adhesive Bond Tension under Shear Stress Modulates Cytosolic Calcium Flux and Neutrophil Inflammatory Response
Authors: VA Morikis, SJ Chen, J Madigan, MH Jo, LC Werba, T Ha, SI Simon
Cells, 2022-09-09;11(18):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
A humanized beta2 integrin knockin mouse reveals localized intra- and extravascular neutrophil integrin activation in�vivo
Authors: L Wen, A Marki, Z Wang, M Orecchioni, J Makings, M Billitti, E Wang, SSA Suthahar, K Kim, WB Kiosses, Z Mikulski, K Ley
Cell Reports, 2022-05-31;39(9):110876.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The tumor suppressor adenomatous polyposis coli regulates T lymphocyte migration
Authors: M Mastrogiov, P Vargas, T Rose, C Cuche, E Esposito, M Juzans, H Laude, A Schneider, M Bernard, S Goyard, C Renaudat, MN Ungeheuer, J Delon, A Alcover, V Di Bartolo
Science Advances, 2022-04-13;8(15):eabl5942.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Mitofusin-2 regulates leukocyte adhesion and beta2 integrin activation
Authors: W Liu, AY Hsu, Y Wang, T Lin, H Sun, JS Pachter, A Groisman, M Imperioli, FW Yungher, L Hu, P Wang, Q Deng, Z Fan
Journal of leukocyte biology, 2021-09-08;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
LFA-1 and Kindlin-3 enable the collaborative transport of SLP-76 microclusters by myosin and dynein motors
Authors: KP Eidell, A Lovy, NR Sylvain, FA Scangarell, HI Muendlein, MJ Ophir, K Nguyen, MC Seminario, SC Bunnell
Journal of Cell Science, 2021-08-27;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Allosteric activation of T�cell antigen receptor signaling by quaternary structure relaxation
Authors: AL Lanz, G Masi, N Porciello, A Cohnen, D Cipria, D Prakaash, Š Bálint, R Raggiaschi, D Galgano, DK Cole, M Lepore, O Dushek, ML Dustin, MSP Sansom, AC Kalli, O Acuto
Cell Reports, 2021-07-13;36(2):109375.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Morphological profiling of human T and NK lymphocytes by high-content cell imaging
Authors: Y German, L Vulliard, A Kamnev, L Pfajfer, J Huemer, AK Mautner, A Rubio, A Kalinichen, K Boztug, A Ferrand, J Menche, L Dupré
Cell Reports, 2021-07-06;36(1):109318.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Asymmetric cell division shapes naive and virtual memory T-cell immunity during ageing
Authors: M Borsa, N Barandun, F Gräbnitz, I Barnstorf, NS Baumann, K Pallmer, S Baumann, D Stark, M Balaz, N Oetiker, F Wagen, C Wolfrum, AK Simon, N Joller, Y Barral, R Spörri, A Oxenius
Nature Communications, 2021-05-11;12(1):2715.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Irisin supports integrin-mediated cell adhesion of lymphocytes
Authors: PK Myint, A Ito, MG Appiah, G Obeng, S Darkwah, E Kawamoto, A Gaowa, EJ Park, M Shimaoka
Biochemistry and Biophysics Reports, 2021-03-08;26(0):100977.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay, ELISA Capture Control -
Stochastic asymmetric repartition of lytic machinery in dividing CD8+ T cells generates heterogeneous killing behavior
Authors: F Lafouresse, R Jugele, S Müller, M Doineau, V Duplan-Ech, E Espinosa, MP Puisségur, S Gadat, S Valitutti
Elife, 2021-01-11;10(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Activation and degranulation of CAR-T cells using engineered antigen-presenting cell surfaces
Authors: Q Dirar, T Russell, L Liu, S Ahn, G Dotti, S Aravamudha, L Conforti, Y Yun
PLoS ONE, 2020-09-25;15(9):e0238819.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Cellular locomotion using environmental topography
Authors: A Reversat, F Gaertner, J Merrin, J Stopp, S Tasciyan, J Aguilera, I de Vries, R Hauschild, M Hons, M Piel, A Callan-Jon, R Voituriez, M Sixt
Nature, 2020-05-13;582(7813):582-585.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
Adhesion of T cells to endothelial cells facilitates blinatumomab-associated neurologic adverse events
Authors: M Klinger, G Zugmaier, V Nägele, ME Goebeler, C Brandl, M Stelljes, H Lassmann, A von Stacke, RC Bargou, P Kufer
Cancer Res., 2019-10-29;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Frontline Science: A flexible kink in the transmembrane domain impairs β2 integrin extension and cell arrest from rolling
Authors: H Sun, Z Fan, AR Gingras, MA Lopez-Rami, MH Ginsberg, K Ley
J. Leukoc. Biol., 2019-09-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
NKG2D/DAP10 Signaling recruits EVL to the cytotoxic synapse to generate F-actin and promote NK cell cytotoxicity
Authors: KM Wilton, BL Overlee, DD Billadeau
J. Cell. Sci., 2019-07-18;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The Extracellular Domain of the β2 Integrin β Subunit (CD18) Is Sufficient for Escherichia coli Hemolysin and Aggregatibacter actinomycetemcomitans Leukotoxin Cytotoxic Activity
Authors: LC Ristow, V Tran, KJ Schwartz, L Pankratz, A Mehle, JD Sauer, RA Welch
MBio, 2019-07-09;10(4):.
Species: Human
Sample Types: Protein
Applications: Western Blot -
Live nanoscopic to mesoscopic topography reconstruction with an optical microscope for chemical and biological samples
Authors: O Theodoly, N Garcia-Sey, F Bedu, X Luo, S Gabriele, T Mignot, J Giermanska, JP Chapel, M Métivier, MP Valignat
PLoS ONE, 2018-12-12;13(12):e0207881.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Cis interaction between sialylated Fc?RIIA and the ?I-domain of Mac-1 limits antibody-mediated neutrophil recruitment
Authors: G Saggu, K Okubo, Y Chen, R Vattepu, N Tsuboi, F Rosetti, X Cullere, N Washburn, S Tahir, AM Rosado, SM Holland, RM Anthony, M Sen, C Zhu, TN Mayadas
Nat Commun, 2018-11-29;9(1):5058.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Biomimetic post-capillary venule expansions for leukocyte adhesion studies
Authors: BL Benson, L Li, JT Myers, RD Dorand, UA Gurkan, AY Huang, RM Ransohoff
Sci Rep, 2018-06-19;8(1):9328.
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Phosphorylation of the ?-chain in the integrin LFA-1 enables ?2-chain phosphorylation and ?-actinin binding required for cell adhesion
Authors: F Jahan, S Madhavan, T Rolova, L Viazmina, M Grönholm, CG Gahmberg
J. Biol. Chem., 2018-06-14;0(0):.
Applications: Bioassay -
A Developed NK-92MI Cell Line with Siglec-7negPhenotype Exhibits High and Sustainable Cytotoxicity against Leukemia Cells
Authors: CH Huang, YJ Liao, TH Fan, TJ Chiou, YH Lin, YC Twu
Int J Mol Sci, 2018-04-04;19(4):.
Applications: Bioassay -
ZAP70 expression enhances chemokine-driven chronic lymphocytic leukemia cell migration and arrest by valency regulation of integrins
Authors: JM Laufer, R Lyck, DF Legler
FASEB J., 2018-03-28;0(0):fj201701452RR.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay, Cell Culture -
The Wiskott-Aldrich Syndrome Protein Contributes to the Assembly of the LFA-1 Nanocluster Belt at the Lytic Synapse
Authors: R Houmadi, D Guipouy, J Rey-Barros, Z Vasconcelo, J Cornet, M Manghi, N Destainvil, S Valitutti, S Allart, L Dupré
Cell Rep, 2018-01-28;22(4):979-991.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
T-Time: A data repository of T cell and calcium release-activated calcium channel activation imagery
Authors: C Arbuckle, M Greenberg, A Bergh, R German, N Sirago, E Linstead
BMC Res Notes, 2017-08-15;10(1):408.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
PKN1 Directs Polarized RAB21 Vesicle Trafficking via RPH3A and Is Important for Neutrophil Adhesion and Ischemia-Reperfusion Injury
Authors: Q Yuan, C Ren, W Xu, B Petri, J Zhang, Y Zhang, P Kubes, D Wu, W Tang
Cell Rep, 2017-06-20;19(12):2586-2597.
Species: Goat
Sample Types: Antibody
Applications: Bioassay -
Changes in clinical laboratory parameters and pharmacodynamic markers in response to blinatumomab treatment of patients with relapsed/refractory ALL
Authors: V Nägele, A Kratzer, G Zugmaier, C Holland, Y Hijazi, MS Topp, N Gökbuget, PA Baeuerle, P Kufer, A Wolf, M Klinger
Exp Hematol Oncol, 2017-05-18;6(0):14.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
P-Selectin and ICAM-1 synergy in mediating THP-1 monocyte adhesion in hemodynamic flow is length dependent
Authors: EE Edwards, SN Thomas
Integr Biol (Camb), 2017-04-18;9(4):313-327.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
A human immunodeficiency syndrome caused by mutations in CARMIL2
Authors: T Schober, T Magg, M Laschinger, M Rohlfs, ND Linhares, J Puchalka, T Weisser, K Fehlner, J Mautner, C Walz, K Hussein, G Jaeger, B Kammer, I Schmid, M Bahia, SD Pena, U Behrends, BH Belohradsk, C Klein, F Hauck
Nat Commun, 2017-01-23;8(0):14209.
Species: Human
Sample Types: Whole Cells
Applications: Migration -
Recruitment of calcineurin to the TCR positively regulates T cell activation
Nat. Immunol, 2016-12-12;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The evolution of multivalent nanoparticle adhesion via specific molecular interactions
Authors: Jered Brackston Haun
Langmuir, 2016-12-05;0(0):.
Applications: Bioassay -
Identification of pathogenic factors potentially involved in Staphylococcus aureus keratitis using proteomics
Exp Eye Res, 2016-08-30;151(0):171-178.
Species: Bacteria - Staphylococcus aureus
Sample Types: Whole Cells
Applications: Bioassay -
Calcium influx through CRAC channels controls actin organization and dynamics at the immune synapse
Elife, 2016-07-21;5(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Interaction between Endothelial Protein C Receptor and Intercellular Adhesion Molecule 1 to Mediate Binding of Plasmodium falciparum-Infected Erythrocytes to Endothelial Cells
MBio, 2016-07-12;7(4):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
WNK1 kinase balances T cell adhesion versus migration in vivo
Nat Immunol, 2016-07-11;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
ARAP, a Novel Adaptor Protein, Is Required for TCR Signaling and Integrin-Mediated Adhesion
Authors: Seung Hee Jung
J Immunol, 2016-06-22;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Multi-Inhibitory Effects of A2A Adenosine Receptor Signaling on Neutrophil Adhesion Under Flow.
Authors: Yago T, Tsukamoto H, Liu Z, Wang Y, Thompson L, McEver R
J Immunol, 2015-09-09;195(8):3880-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The Neurorepellent Slit2 Inhibits Postadhesion Stabilization of Monocytes Tethered to Vascular Endothelial Cells.
Authors: Mukovozov I, Huang Y, Zhang Q, Liu G, Siu A, Sokolskyy Y, Patel S, Hyduk S, Kutryk M, Cybulsky M, Robinson L
J Immunol, 2015-08-21;195(7):3334-44.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Enhanced Chemokine Receptor Recycling and Impaired S1P1 Expression Promote Leukemic Cell Infiltration of Lymph Nodes in Chronic Lymphocytic Leukemia.
Authors: Patrussi L, Capitani N, Martini V, Pizzi M, Trimarco V, Frezzato F, Marino F, Semenzato G, Trentin L, Baldari C
Cancer Res, 2015-08-17;75(19):4153-63.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Homeostatic regulation of T cell trafficking by a B cell-derived peptide is impaired in autoimmune and chronic inflammatory disease.
Authors: Chimen M, McGettrick H, Apta B, Kuravi S, Yates C, Kennedy A, Odedra A, Alassiri M, Harrison M, Martin A, Barone F, Nayar S, Hitchcock J, Cunningham A, Raza K, Filer A, Copland D, Dick A, Robinson J, Kalia N, Walker L, Buckley C, Nash G, Narendran P, Rainger G
Nat Med, 2015-04-20;21(5):467-75.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
TAGLN2 regulates T cell activation by stabilizing the actin cytoskeleton at the immunological synapse.
Authors: Na B, Kim H, Piragyte I, Oh H, Kwon M, Akber U, Lee H, Park D, Song W, Park Z, Im S, Rho M, Hyun Y, Kim M, Jun C
J Cell Biol, 2015-04-13;209(1):143-62.
Species: Human
Sample Types: Whole Cells
Applications: Adhesion Assay -
Glycopeptide analogues of PSGL-1 inhibit P-selectin in vitro and in vivo.
Authors: Krishnamurthy V, Sardar M, Ying Y, Song X, Haller C, Dai E, Wang X, Hanjaya-Putra D, Sun L, Morikis V, Simon S, Woods R, Cummings R, Chaikof E
Nat Commun, 2015-03-31;6(0):6387.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Chemokine-coupled beta2 integrin-induced macrophage Rac2-Myosin IIA interaction regulates VEGF-A mRNA stability and arteriogenesis.
Authors: Morrison A, Yarovinsky T, Young B, Moraes F, Ross T, Ceneri N, Zhang J, Zhuang Z, Sinusas A, Pardi R, Schwartz M, Simons M, Bender J
J Exp Med, 2014-09-01;211(10):1957-68.
Applications: Bioassay -
B-Raf regulation of integrin alpha4beta1-mediated resistance to shear stress through changes in cell spreading and cytoskeletal association in T cells.
Authors: Brown W, Khalili J, Rodriguez-Cruz T, Lizee G, McIntyre B
J Biol Chem, 2014-06-16;289(33):23141-53.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Phosphorylation of Rab5a protein by protein kinase C is crucial for T-cell migration.
Authors: Ong S, Freeley M, Skubis-Zegadlo J, Fazil M, Kelleher D, Fresser F, Baier G, Verma N, Long A
J Biol Chem, 2014-05-28;289(28):19420-34.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
ICAM-2 facilitates luminal interactions between neutrophils and endothelial cells in vivo.
Authors: Halai, Krishma, Whiteford, James, Ma, Bin, Nourshargh, Sussan, Woodfin, Abigail
J Cell Sci, 2013-12-06;127(0):620-9.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Selective inhibition of KCa3.1 channels mediates adenosine regulation of the motility of human T cells.
Authors: Chimote, Ameet A, Hajdu, Peter, Kucher, Vladimir, Boiko, Nina, Kuras, Zerrin, Szilagyi, Orsolya, Yun, Yeo-Heun, Conforti, Laura
J Immunol, 2013-11-13;191(12):6273-80.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Modulation of integrin activation and signaling by alpha1/alpha1'-helix unbending at the junction.
Authors: Zhang C, Liu J, Jiang X, Haydar N, Zhang C, Shan H, Zhu J
J Cell Sci, 2013-10-21;126(0):5735-47.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Distinct binding affinities of Mac-1 and LFA-1 in neutrophil activation.
Authors: Li N, Mao D, Lu S, Tong C, Zhang Y, Long M
J Immunol, 2013-03-20;190(8):4371-81.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Toxoplasma gondii modulates the dynamics of human monocyte adhesion to vascular endothelium under fluidic shear stress.
Authors: Harker K, Ueno N, Wang T, Bonhomme C, Liu W, Lodoen M
J Leukoc Biol, 2013-03-13;93(5):789-800.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Wiskott-Aldrich syndrome protein (WASp) and N-WASp are involved in the regulation of NK-cell migration upon NKG2D activation.
Eur J Immunol, 2012-08-01;42(8):2142-51.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Leukocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction induces a novel genetic signature resulting in T-cells refractory to transforming growth factor-beta signaling.
Authors: Verma N, Dempsey E, Long A, Davies A, Barry S, Fallon P, Volkov Y, Kelleher D
J Biol Chem, 2012-06-15;287(32):27204-16.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
CD29 expressed on plasma cells is activated by divalent cations and soluble CD106 contained in the bone marrow plasma: refractory activation is associated with enhanced proliferation and exit of clonal plasma cells to circulation in multiple myeloma patients.
Authors: Martinez-Vinambres E, Garcia-Trujillo JA, Rodriguez-Martin E, Villar LM, Coll J, Roldan E
Leukemia, 2011-12-02;26(5):1098-105.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Epstein-Barr virus infection of polarized epithelial cells via the basolateral surface by memory B cell-mediated transfer infection.
Authors: Shannon-Lowe C, Rowe M
PLoS Pathog., 2011-05-05;7(5):e1001338.
Species: Human
Sample Types: Whole Cells
Applications: Adhesion Assay -
JAM-L-mediated leukocyte adhesion to endothelial cells is regulated in cis by alpha4beta1 integrin activation.
Authors: Luissint AC, Lutz PG, Calderwood DA, Couraud PO, Bourdoulous S
J. Cell Biol., 2008-12-08;183(6):1159-73.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
A mechanism for antibody-mediated outside-in activation of LFA-1.
Authors: Carreno R, Li D, Sen M, Nira I, Yamakawa T, Ma Q, Legge GB
J. Biol. Chem., 2008-01-16;283(16):10642-8.
Species: Human
Sample Types: Recombinant Protein
Applications: Surface Plasmon Resonance -
Lymph node chemokines promote sustained T lymphocyte motility without triggering stable integrin adhesiveness in the absence of shear forces.
Authors: Woolf E, Grigorova I, Sagiv A, Grabovsky V, Feigelson SW, Shulman Z, Hartmann T, Sixt M, Cyster JG, Alon R
Nat. Immunol., 2007-08-26;8(10):1076-85.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Activation of CR3-mediated phagocytosis by MSP requires the RON receptor, tyrosine kinase activity, phosphatidylinositol 3-kinase, and protein kinase C zeta.
Authors: Lutz MA, Correll PH
J. Leukoc. Biol., 2003-06-01;73(6):802-14.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
CCR6 colocalizes with CD18 and enhances adhesion to activated endothelial cells in CCR6-transduced Jurkat T cells.
Authors: Maki W, Morales RE, Carroll VA, Telford WG, Knibbs RN, Stoolman LM, Hwang ST
J. Immunol., 2002-09-01;169(5):2346-53.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay
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