Recombinant Human IFN-gamma Protein

Mapping the epigenomic landscape of human monocytes following innate immune activation reveals context-specific mechanisms driving endotoxin tolerance
Authors: Amarasinghe, HE;Zhang, P;Whalley, JP;Allcock, A;Migliorini, G;Brown, AC;Scozzafava, G;Knight, JC;
BMC genomics
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Tyrosine phosphorylation of IRF3 by BLK facilitates its sufficient activation and innate antiviral response
Authors: Li, WW;Fan, XX;Zhu, ZX;Cao, XJ;Zhu, ZY;Pei, DS;Wang, YZ;Zhang, JY;Wang, YY;Zheng, HX;
PLoS pathogens
Species: Human
Sample Types: Transfected Whole Cells
Applications: Bioassay

Human GBP1 facilitates the rupture of the Legionella-containing vacuole and inflammasome activation
Authors: Bass, AR;Egan, MS;Alexander-Floyd, J;Lopes Fischer, N;Doerner, J;Shin, S;
mBio
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Regulation of human interferon signaling by transposon exonization
Authors: Pasquesi, GIM;Allen, H;Ivancevic, A;Barbachano-Guerrero, A;Joyner, O;Guo, K;Simpson, DM;Gapin, K;Horton, I;Nguyen, L;Yang, Q;Warren, CJ;Florea, LD;Bitler, BG;Santiago, ML;Sawyer, SL;Chuong, EB;
bioRxiv : the preprint server for biology
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

DUX4 expression in cancer induces a metastable early embryonic totipotent program
Authors: Smith, AA;Nip, Y;Bennett, SR;Hamm, DC;Lemmers, RJLF;van der Vliet, PJ;Setty, M;van der Maarel, SM;Tapscott, SJ;
Cell reports
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Comprehensive analysis of E47?like factors and verification of ELF4 in clear cell renal cell carcinoma
Authors: Lu, J;Zhang, Q;Mo, L;Chen, W;Mao, L;
Oncology letters
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Macrophage Profiling in Head and Neck Cancer to Improve Patient Prognosis and Assessment of Cancer Cell-Macrophage Interactions Using Three-Dimensional Coculture Models
Authors: Mhaidly, N;Journe, F;Najem, A;Stock, L;Trelcat, A;Dequanter, D;Saussez, S;Descamps, G;
International journal of molecular sciences
Species: Human
Sample Types: Spheroids
Applications: Bioassay

Plug-and-play protein biosensors using aptamer-regulated in vitro transcription
Authors: Lee, H;Xie, T;Yu, X;Schaffter, SW;Schulman, R;
bioRxiv : the preprint server for biology
Species: Human
Sample Types: Recombinant Protein
Applications: Bioassay

Inhibition of METTL3 results in a cell-intrinsic interferon response that enhances anti-tumour immunity
Authors: Guirguis, AA;Ofir-Rosenfeld, Y;Knezevic, K;Blackaby, W;Hardick, D;Chan, YC;Motazedian, A;Gillespie, A;Vassiliadis, D;Lam, EY;Tran, K;Andrews, B;Harbour, ME;Vasiliauskaite, L;Saunders, CJ;Tsagkogeorga, G;Azevedo, A;Obacz, J;Pilka, ES;Carkill, M;MacPherson, L;Wainwright, EN;Liddicoat, B;Blyth, BJ;Albertella, MR;Rausch, O;Dawson, MA;
Cancer discovery
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IMT504 protects beta cells against apoptosis and maintains beta cell identity, without modifying proliferation
Authors: Converti, A;Bianchi, MS;Martinez, MD;Montaner, AD;Lux-Lantos, V;Bonaventura, MM;
Physiological reports
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Exosome from IFN-gamma -Primed Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Improved Skin Inflammation and Barrier Function
Authors: Yoon, J;Lee, SK;Park, A;Lee, J;Jung, I;Song, KB;Choi, EJ;Kim, S;Yu, J;
International journal of molecular sciences
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Senescence-Driven Inflammatory and Trophic Microenvironment Imprints Mesenchymal Stromal/Stem Cells in Osteoarthritic Patients
Authors: Fusi, G;Constantinides, M;Fissoun, C;Pichard, L;Pers, YM;Ferreira-Lopez, R;Pantesco, V;Poulet, C;Malaise, O;De Seny, D;Lemaitre, JM;Jorgensen, C;Brondello, JM;
Biomedicines
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

PLSCR1 is a cell-autonomous defence factor against SARS-CoV-2 infection
Authors: Xu, D;Jiang, W;Wu, L;Gaudet, RG;Park, ES;Su, M;Cheppali, SK;Cheemarla, NR;Kumar, P;Uchil, PD;Grover, JR;Foxman, EF;Brown, CM;Stansfeld, PJ;Bewersdorf, J;Mothes, W;Karatekin, E;Wilen, CB;MacMicking, JD;
Nature
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Dynamics of Ex Vivo Mesenchymal Stromal Cell Potency under Continuous Perfusion
Authors: Doshi, A;Erickson, P;Teryek, M;Parekkadan, B;
International journal of molecular sciences
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

High levels of endothelial ICAM-1 prohibit natalizumab mediated abrogation of CD4+ T cell arrest on the inflamed BBB under flow in vitro
Authors: Soldati, S;B�r, A;Vladymyrov, M;Glavin, D;McGrath, JL;Gosselet, F;Nishihara, H;Goelz, S;Engelhardt, B;
Journal of neuroinflammation
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The HDAC2-SP1 axis orchestrates pro-tumor macrophage polarization
Authors: Zheng, X;Sarode, P;Weigert, A;Turkowski, K;Chelladurai, P;G�nther, S;Kuenne, C;Winter, H;Stenzinger, A;Reu, S;Grimminger, F;Stiewe, T;Seeger, W;Pullamsetti, SS;Savai, R;
Cancer research
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Small-molecule PIK-93 modulates the tumor microenvironment to improve immune checkpoint blockade response
Authors: CY Lin, KY Huang, SH Kao, MS Lin, CC Lin, SC Yang, WC Chung, YH Chang, RJ Chein, PC Yang
Science Advances, 2023-04-07;9(14):eade9944.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Aryl hydrocarbon receptor activity downstream of IL-10 signaling is required to promote regulatory functions in human dendritic cells
Authors: D Avancini, A Testori, L Fresolone, G Andolfi, M Vuono, V Martinelli, FR Santoni de, S Gregori
Cell Reports, 2023-03-03;42(3):112193.
Species: Human
Sample Types: Protein
Applications: Reference Standard

PD-1highCXCR5-CD4+ peripheral helper T�cells promote CXCR3+ plasmablasts in human acute viral infection
Authors: H Asashima, S Mohanty, M Comi, WE Ruff, KB Hoehn, P Wong, J Klein, C Lucas, I Cohen, S Coffey, N Lele, L Greta, K Raddassi, O Chaudhary, A Unterman, B Emu, SH Kleinstein, RR Montgomery, A Iwasaki, CS Dela Cruz, N Kaminski, AC Shaw, DA Hafler, TS Sumida
Cell Reports, 2023-01-02;0(0):111895.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Intestinal epithelial BLT1 promotes mucosal repair
Authors: S Hayashi, CK Muraleedha, M Oku, S Tomar, SP Hogan, M Quiros, CA Parkos, A Nusrat
JCI Insight, 2022-12-08;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CRISPR/Cas9 Edited RAS & MEK Mutant Cells Acquire BRAF and MEK Inhibitor Resistance with MEK1 Q56P Restoring Sensitivity to MEK/BRAF Inhibitor Combo and KRAS G13D Gaining Sensitivity to Immunotherapy
Authors: E Turner, L Chen, JG Foulke, Z Gu, F Tian
Cancers, 2022-11-05;14(21):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Cytokine responsive networks in human colonic epithelial organoids unveil a molecular classification of inflammatory bowel disease
Authors: P Pavlidis, A Tsakmaki, A Treveil, K Li, D Cozzetto, F Yang, U Niazi, BH Hayee, M Saqi, J Friedman, T Korcsmaros, G Bewick, N Powell
Cell Reports, 2022-09-27;40(13):111439.
Species: Human
Sample Types: Organoid
Applications: Bioassay

NAD+ metabolism drives astrocyte proinflammatory reprogramming in central nervous system autoimmunity
Authors: T Meyer, D Shimon, S Youssef, G Yankovitz, A Tessler, T Chernobyls, A Gaoni-Yoge, R Perelroize, N Budick-Har, L Steinman, L Mayo
Proceedings of the National Academy of Sciences of the United States of America, 2022-08-22;119(35):e2211310119.
Species: Human
Sample Types: Whole Cell
Applications: Cell Culture

STUB1 is an intracellular checkpoint for interferon gamma sensing
Authors: S Ng, S Lim, ACN Sim, R Mangadu, A Lau, C Zhang, SB Martinez, A Chandramoh, UM Lim, SSW Ho, SC Chang, P Gopal, LZ Hong, A Schwaid, AZ Fernandis, A Loboda, C Li, U Phan, B Henry, AW Partridge
Scientific Reports, 2022-08-18;12(1):14087.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Microglia Impairs Proliferation and Induces Senescence In-Vitro in NGF Releasing Cells Used in Encapsulated Cell Biodelivery for Alzheimer's Disease Therapy
Authors: S Mitra, R Gera, J Sundheimer, M Lemee, LU Wahlberg, B Linderoth, M Eriksdotte, H Behbahani
International Journal of Molecular Sciences, 2022-08-12;23(16):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IFN-gamma stimulated murine and human neurons mount anti-parasitic defenses against the intracellular parasite Toxoplasma gondii
Authors: S Chandrasek, JA Kochanowsk, EF Merritt, JS Lagas, A Swannigan, AA Koshy
Nature Communications, 2022-08-08;13(1):4605.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Loss of immunity-related GTPase GM4951 leads to nonalcoholic fatty liver disease without obesity
Authors: Z Zhang, Y Xun, S Rong, L Yan, JA SoRelle, X Li, M Tang, K Keller, S Ludwig, EMY Moresco, B Beutler
Nature Communications, 2022-07-16;13(1):4136.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IFNgamma-induced PD-L1 expression in ovarian cancer cells is regulated by JAK1, STAT1 and IRF1 signaling
Authors: S Padmanabha, B Gaire, Y Zou, MM Uddin, I Vancurova
Cellular Signalling, 2022-07-09;97(0):110400.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Hypo-osmotic stress induces the epithelial alarmin IL-33 in the colonic barrier of ulcerative colitis
Authors: MD Gundersen, KB Larsen, KM Johnsen, R Goll, J Florholmen, G Haraldsen
Scientific Reports, 2022-07-07;12(1):11550.
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay

In vitro assessment of the anti-inflammatory and skin-moisturizing effects of Filipendula palmata (Pall.) Maxim. On human keratinocytes and identification of its bioactive phytochemicals
Authors: XJ Mi, JK Kim, S Lee, SK Moon, YJ Kim, H Kim
Journal of ethnopharmacology, 2022-07-07;296(0):115523.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Long-term survival in non-human primates of stem cell-derived, MHC-unmatched corneal epithelial cell sheets
Authors: Y Yoshinaga, T Soma, S Azuma, K Maruyama, Y Hashikawa, T Katayama, Y Sasamoto, H Takayanagi, N Hosen, T Shiina, K Ogasawara, R Hayashi, K Nishida
Stem Cell Reports, 2022-06-23;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Membrane-Tethered Mucin 1 Is Stimulated by Interferon and Virus Infection in Multiple Cell Types and Inhibits Influenza A Virus Infection in Human Airway Epithelium
Authors: E Iverson, K Griswold, D Song, TB Gagliardi, K Hamidzadeh, M Kesimer, S Sinha, M Perry, GA Duncan, MA Scull
MBio, 2022-06-14;0(0):e0105522.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IgM anti-ACE2 autoantibodies in severe COVID-19 activate complement and perturb vascular endothelial function
Authors: L Casciola-R, DR Thiemann, F Andrade, MI Trejo-Zamb, EK Leonard, JB Spangler, NE Skinner, J Bailey, S Yegnasubra, R Wang, AM Vaghasia, A Gupta, AL Cox, SC Ray, RM Linville, Z Guo, PC Searson, CE Machamer, S Desiderio, LM Sauer, O Laeyendeck, BT Garibaldi, L Gao, M Damarla, PM Hassoun, JE Hooper, CA Mecoli, L Christophe, L Gutierrez-, Q Yang, D Hines, WA Clarke, RE Rothman, A Pekosz, KZ Fenstermac, Z Wang, SL Zeger, A Rosen
JCI Insight, 2022-05-09;7(9):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Dendrobium nobile Lindley Administration Attenuates Atopic Dermatitis-like Lesions by Modulating Immune Cells
Authors: S Hong, EY Kim, SE Lim, JH Kim, Y Sohn, HS Jung
International Journal of Molecular Sciences, 2022-04-18;23(8):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Cooperative effects of RIG-I-like receptor signaling and IRF1 on DNA damage-induced cell death
Authors: DY Zander, SS Burkart, S Wüst, VG Magalhães, M Binder
Cell Death & Disease, 2022-04-18;13(4):364.
Species: Human
Sample Types: Whole Cell
Applications: Bioassay

Inhibiting Type I arginine methyltransferase activity promotes the T cell mediated antitumor immune response
Authors: A Fedoriw, L Shi, S O'Brien, KN Smitheman, Y Wang, J Hou, C Sherk, S Rajapurkar, J Laraio, LJ Williams, C Xu, G Han, Q Feng, MT Bedford, L Wang, O Barbash, RG Kruger, P Hwu, HP Mohammad, W Peng
Cancer Immunology Research, 2022-04-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The Thermal Dose of Photothermal Therapy Generates Differential Immunogenicity in Human Neuroblastoma Cells
Authors: P Sekhri, DK Ledezma, A Shukla, EE Sweeney, R Fernandes
Cancers, 2022-03-11;14(6):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Interferon-gamma promotes monocyte-mediated lung injury during influenza infection
Authors: T Schmit, K Guo, JK Tripathi, Z Wang, B McGregor, M Klomp, G Ambigapath, R Mathur, J Hur, M Pichichero, J Kolls, MN Khan
Cell Reports, 2022-03-01;38(9):110456.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MMP-10 from M1 macrophages promotes pulmonary vascular remodeling and pulmonary arterial hypertension
Authors: PL Chi, CC Cheng, CC Hung, MT Wang, HY Liu, MW Ke, MC Shen, KC Lin, SH Kuo, PP Hsieh, SR Wann, WC Huang
International journal of biological sciences, 2022-01-01;18(1):331-348.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Novel Kinase Inhibitor AX-0085 Inhibits Interferon-gamma-Mediated Induction of PD-L1 Expression and Promotes Immune Reaction to Lung Adenocarcinoma Cells
Authors: J Kim, H Jang, GJ Lee, Y Hur, J Keum, JK Jo, SE Yun, SJ Park, YJ Park, MJ Choi, KS Kim, J Kim
Cells, 2021-12-22;11(1):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Inhibitor of growth protein 3 epigenetically silences endogenous retroviral elements and prevents innate immune activation
Authors: Y Song, G Hou, J Diep, YS Ooi, NS Akopyants, SM Beverley, JE Carette, HB Greenberg, S Ding
Nucleic Acids Research, 2021-12-16;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

SOX10 requirement for melanoma tumor growth is due, in part, to immune-mediated effects
Authors: SR Rosenbaum, M Tiago, S Caksa, C Capparelli, TJ Purwin, G Kumar, M Glasheen, D Pomante, D Kotas, I Chervoneva, AE Aplin
Cell Reports, 2021-12-07;37(10):110085.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Stress increases MHC-I expression in dopaminergic neurons and induces autoimmune activation in Parkinson's disease
Authors: BY Wang, YY Ye, C Qian, HB Zhang, HX Mao, LP Yao, X Sun, GH Lu, SZ Zhang
Neural regeneration research, 2021-12-01;16(12):2521-2527.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Glucose metabolism and pyruvate carboxylase enhance glutathione synthesis and restrict oxidative stress in pancreatic islets
Authors: A Fu, L van Rooyen, L Evans, N Armstrong, D Avizonis, T Kin, GH Bird, A Reddy, ET Chouchani, M Liesa-Roig, LD Walensky, AMJ Shapiro, NN Danial
Cell Reports, 2021-11-23;37(8):110037.
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay

Demystifying the long noncoding RNA landscape of small EVs derived from human mesenchymal stromal cells
Authors: CW Lee, YF Chen, AW Hsiao, AY Wang, OY Shen, BY Wang, LWC Ho, WT Lin, CHJ Choi, OK Lee
Journal of advanced research, 2021-11-19;39(0):73-88.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

TM4SF5-dependent crosstalk between hepatocytes and macrophages to reprogram the inflammatory environment
Authors: E Kim, H Um, J Park, JW Jung, JE Kim, H Lee, EA Shin, Y Pinanga, H Lee, SH Nam, JW Lee
Cell Reports, 2021-11-16;37(7):110018.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Proteasome inhibitors restore the STAT1 pathway and enhance the expression of MHC class I on human colon cancer cells
Authors: YH Liang, KH Chen, JH Tsai, YM Cheng, CC Lee, CH Kao, KY Chan, YT Chen, WL Hsu, KH Yeh
Journal of Biomedical Science, 2021-11-10;28(1):75.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Histone deacetylase 5 deacetylates the phosphatase PP2A for positively regulating NF-kappaB signaling
Authors: C Xu, J Tang, Q Yang, H Zhao, Y Liu, J Cao, Y Zhou, X Chen, J Chen
The Journal of Biological Chemistry, 2021-11-03;0(0):101380.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Phospholipase A2 enzymes represent a shared pathogenic pathway in psoriasis and pityriasis rubra pilaris
Authors: S Shao, J Chen, WR Swindell, LC Tsoi, X Xing, F Ma, R Uppala, MK Sarkar, O Plazyo, AC Billi, R Wasikowski, KM Smith, P Honore, VE Scott, E Maverakis, JM Kahlenberg, G Wang, NL Ward, PW Harms, JE Gudjonsson
JCI Insight, 2021-10-22;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Comparative Analysis of Six IRF Family Members in Alveolar Epithelial Cell-Intrinsic Antiviral Responses
Authors: S Wüst, P Schad, S Burkart, M Binder
Cells, 2021-09-30;10(10):.
Species: Human
Sample Types: Whole Cell
Applications: Stimulation

IFN-gamma Licensing Does Not Enhance the Reduced Immunomodulatory Potential and Migratory Ability of Differentiation-Induced Porcine Bone Marrow-Derived Mesenchymal Stem Cells in an In Vitro Xenogeneic Application
Authors: HJ Lee, HD Kim, CH Jo, EY Bok, SB Kim, SL Lee, M Jang, SG Bae, SH Yun, SJ Kim, GJ Rho, WJ Lee
BioMed Research International, 2021-09-04;2021(0):4604856.
Species: Porcine
Sample Types: Whole Cells
Applications: Bioassay

Impact of Type 2 Diabetes Mellitus on the Immunoregulatory Characteristics of Adipose Tissue-Derived Mesenchymal Stem Cells
Authors: N Abu-Shahba, M Mahmoud, AM El-Erian, MI Husseiny, G Nour-Eldee, I Helwa, K Amr, M ElHefnawi, AI Othman, SA Ibrahim, O Azmy
The international journal of biochemistry & cell biology, 2021-08-26;0(0):106072.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Impaired immunomodulatory capacity in adipose tissue-derived mesenchymal stem/stromal cells isolated from obese patients
Authors: XY Zhu, N Klomjit, SM Conley, MM Ostlie, KL Jordan, A Lerman, LO Lerman
Journal of Cellular and Molecular Medicine, 2021-08-21;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The effects of T-DXd on the expression of HLA class I and chemokines CXCL9/10/11 in HER2-overexpressing gastric cancer cells
Authors: S Nakajima, K Mimura, T Matsumoto, AK Thar Min, M Ito, H Nakano, P Neupane, Y Kanke, H Okayama, M Saito, T Momma, Y Watanabe, H Hanayama, S Hayase, Z Saze, K Kono
Scientific Reports, 2021-08-19;11(1):16891.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Hofbauer Cells Spread Listeria monocytogenes among Placental Cells and Undergo Pro-Inflammatory Reprogramming while Retaining Production of Tolerogenic Factors
Authors: S Azari, LJ Johnson, A Webb, SM Kozlowski, X Zhang, K Rood, A Amer, S Seveau
MBio, 2021-08-17;12(4):e0184921.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro
Authors: C Prelli Boz, R Nchioua, M Volcic, L Koepke, J Krüger, D Schütz, S Heller, CM Stürzel, D Kmiec, C Conzelmann, J Müller, F Zech, E Braun, R Gro beta, L Wettstein, T Weil, J Wei beta, F Diofano, AA Rodríguez, S Wiese, D Sauter, J Münch, C Goffinet, A Catanese, M Schön, TM Boeckers, S Stenger, K Sato, S Just, A Kleger, KMJ Sparrer, F Kirchhoff
Nature Communications, 2021-07-28;12(1):4584.
Species: Human
Sample Types: Organoid
Applications: Bioassay

Mechanistic insight into bacterial entrapment by septin cage reconstitution
Authors: D Lobato-Már, J Xu, GÖ Güler, A Ojiakor, M Pilhofer, S Mostowy
Nature Communications, 2021-07-23;12(1):4511.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The inflammatory regulation of TRPA1 expression in human A549 lung epithelial cells
Authors: S Luostarine, M Hämäläinen, N Hatano, K Muraki, E Moilanen
Pulmonary pharmacology & therapeutics, 2021-07-21;70(0):102059.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

FKBP3 Induces Human Immunodeficiency Virus Type 1 Latency by Recruiting Histone Deacetylase 1/2 to the Viral Long Terminal Repeat
Authors: X Yang, X Zhao, Y Zhu, Y Shen, Y Wang, P Lu, Z Jiang, H Pan, J Yang, J Xun, L Zhao, J Wang, Z Liang, X Shen, Y Liang, Q Lin, H Liang, L Jin, D Zhang, J Liu, B Wang, S Jiang, J Xu, H Wu, H Lu, H Zhu
MBio, 2021-07-20;0(0):e0079521.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Disrupting Mitochondrial Electron Transfer Chain Complex I Decreases Immune Checkpoints in Murine and Human Acute Myeloid Leukemic Cells
Authors: R Luna-Yolba, J Marmoiton, V Gigo, X Marechal, E Boet, A Sahal, N Alet, I Abramovich, E Gottlieb, V Visentin, MR Paillasse, JE Sarry
Cancers, 2021-07-13;13(14):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Skullcapflavone II Suppresses TNF-alpha/IFN-gamma-Induced TARC, MDC, and CTSS Production in HaCaT Cells
Authors: H Lee, DH Lee, JH Oh, JH Chung
International Journal of Molecular Sciences, 2021-06-16;22(12):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Oxidized-Desialylated Low-Density Lipoprotein Inhibits the Antitumor Functions of Lymphokine Activated Killer Cells
Authors: JS Aguilar Dí, HL Glenn, M Knappenber, CR Borges
Journal of Cancer, 2021-06-16;12(16):4993-5004.
Species: Human
Sample Types: Recombinant Protein
Applications: ELISA (Capture)

Identification of genes modulated by interferon gamma in breast cancer cells
Authors: AC Tecalco-Cr, M Macías-Sil, JO Ramírez-Ja, B Méndez-Amb
Biochemistry and Biophysics Reports, 2021-06-16;27(0):101053.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

STAT1 potentiates oxidative stress revealing a targetable vulnerability that increases phenformin efficacy in breast cancer
Authors: SP Totten, YK Im, E Cepeda Cañ, O Najyb, A Nguyen, S Hébert, R Ahn, K Lewis, B Lebeau, R La Selva, V Sabourin, C Martínez, P Savage, H Kuasne, D Avizonis, N Santos Mar, C Chabot, A Aguilar-Ma, ML Goulet, M Dankner, M Witcher, K Petrecca, M Basik, M Pollak, I Topisirovi, R Lin, PM Siegel, CL Kleinman, M Park, J St-Pierre, J Ursini-Sie
Nature Communications, 2021-06-03;12(1):3299.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The discriminatory power of the T cell receptor
Authors: J Pettmann, A Huhn, E Abu Shah, MA Kutuzov, DB Wilson, ML Dustin, SJ Davis, PA van der Me, O Dushek
Elife, 2021-05-25;10(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Proteoglycan 4 Modulates Osteogenic Smooth Muscle Cell Differentiation during Vascular Remodeling and Intimal Calcification
Authors: T Seime, AC Akbulut, ML Liljeqvist, A Siika, H Jin, G Winski, RH van Gorp, E Karlöf, M Lengquist, AJ Buckler, M Kronqvist, OJ Waring, JHN Lindeman, EAL Biessen, L Maegdefess, A Razuvaev, LJ Schurgers, U Hedin, L Matic
Cells, 2021-05-21;10(6):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Claudin-Low Breast Cancer Inflammatory Signatures Support Polarization of M1-Like Macrophages with Protumoral Activity
Authors: MC Suárez-Arr, A Méndez-Ten, V Pérez-Kold, EM Fuentes-Pa
Cancers, 2021-05-07;13(9):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Chemotherapy agents stimulate dendritic cells against human colon cancer cells through upregulation of the transporter associated with antigen processing
Authors: YH Liang, JH Tsai, YM Cheng, KY Chan, WL Hsu, CC Lee, KH Chen, KH Yeh
Scientific Reports, 2021-04-27;11(1):9080.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The Conversion of Human Tissue-Like Inflammatory Monocytes Into Macrophages.
Authors: Bsat M, Mehta H, Rubio M, Sarfati M
Curr Protoc, 2021-03-01;1(3):e74.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma
Authors: L Jerby-Arno, C Neftel, ME Shore, HR Weisman, ND Mathewson, MJ McBride, B Haas, B Izar, A Volorio, G Boulay, L Cironi, AR Richman, LC Broye, JM Gurski, CC Luo, R Mylvaganam, L Nguyen, S Mei, JC Melms, C Georgescu, O Cohen, JE Buendia-Bu, A Segerstolp, M Sud, MS Cuoco, D Labes, S Gritsch, DR Zollinger, N Ortogero, JM Beechem, G Petur Niel, I Chebib, T Nguyen-Ngo, M Montemurro, GM Cote, E Choy, I Letovanec, S Cherix, N Wagle, PK Sorger, AB Haynes, JT Mullen, I Stamenkovi, MN Rivera, C Kadoch, KW Wucherpfen, O Rozenblatt, ML Suvà, N Riggi, A Regev
Nature Medicine, 2021-01-25;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Tissue-specific endothelial cell heterogeneity contributes to unequal inflammatory responses
Authors: H Gunawardan, T Romero, N Yao, S Heidt, A Mulder, DA Elashoff, NM Valenzuela
Scientific Reports, 2021-01-21;11(1):1949.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

SHP2 blockade enhances anti-tumor immunity via tumor cell intrinsic and extrinsic mechanisms
Authors: Y Wang, M Mohseni, A Grauel, JE Diez, W Guan, S Liang, JE Choi, M Pu, D Chen, T Laszewski, S Schwartz, J Gu, L Mansur, T Burks, L Brodeur, R Velazquez, S Kovats, B Pant, G Buruzula, E Deng, JT Chen, F Sari-Sarra, C Dornelas, M Varadaraja, H Yu, C Liu, J Lim, HX Hao, X Jiang, A Malamas, MJ LaMarche, FC Geyer, M McLaughlin, C Costa, J Wagner, D Ruddy, P Jayaraman, ND Kirkpatric, P Zhang, O Iartchouk, K Aardalen, V Cremasco, G Dranoff, JA Engelman, S Silver, H Wang, WD Hastings, S Goldoni
Scientific Reports, 2021-01-14;11(1):1399.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Dendritic cells focus CTL responses toward highly conserved and topologically important HIV-1 epitopes
Authors: TM Garcia-Bat, ML Palma, RR Anderko, DC Hsu, J Ananworani, BT Korber, GD Gaiha, N Phanuphak, R Thomas, S Tovanabutr, BD Walker, JW Mellors, PA Piazza, E Kroon, SA Riddler, NL Michael, CR Rinaldo, RB Mailliard, I4C and RV
EBioMedicine, 2021-01-12;63(0):103175.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Repurposing screen identifies Amlodipine as an inducer of PD-L1 degradation and antitumor immunity
Authors: C Li, H Yao, H Wang, JY Fang, J Xu
Oncogene, 2020-12-15;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Interferon-gamma promotes iron export in human macrophages to limit intracellular bacterial replication
Authors: R Abreu, L Essler, P Giri, F Quinn
PLoS ONE, 2020-12-08;15(12):e0240949.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

M1 Macrophage-Derived Exosomal MicroRNA-326 Suppresses Hepatocellular Carcinoma Cell Progression Via Mediating NF-&kappaB Signaling Pathway
Authors: ZZ Bai, HY Li, CH Li, CL Sheng, XN Zhao
Nanoscale research letters, 2020-12-02;15(1):221.
Species: Human
Sample Types: Whole Cells

18F-FHBG PET-CT Reporter Gene Imaging of Adoptive CIK Cell Transfer Immunotherapy for Breast Cancer in a Mouse Model
Authors: X Li, G Yin, W Ji, J Liu, Y Zhang, J Wang, X Zhu, L Zhu, D Dai, W Ma, W Xu
Onco Targets Ther, 2020-11-13;13(0):11659-11668.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Interferon-&gamma signaling synergizes with LRRK2 in neurons and microglia derived from human induced pluripotent stem cells
Authors: V Panagiotak, D Ivanyuk, S De Cicco, W Haq, A Arsi?, C Yu, D Messelodi, M Oldrati, DC Schöndorf, MJ Perez, RP Cassatella, M Jakobi, N Schneiderh, T Gasser, I Niki?-Spie, M Deleidi
Nat Commun, 2020-10-14;11(1):5163.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Proinflammatory cytokines and ARDS pulmonary edema fluid induce CD40 on human mesenchymal stromal cells-A potential mechanism for immune modulation
Authors: EM Wilfong, R Croze, X Fang, M Schwede, E Niemi, GY López, JW Lee, MC Nakamura, MA Matthay
PLoS ONE, 2020-10-06;15(10):e0240319.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

ISG15 Connects Autophagy and IFN-&gamma-Dependent Control of Toxoplasma gondii Infection in Human Cells
Authors: J Bhushan, JB Radke, YC Perng, M Mcallaster, DJ Lenschow, HW Virgin, LD Sibley
MBio, 2020-10-06;11(5):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Mesenchymal stem/stromal cell quality control: validation of mixed lymphocyte reaction assay using flow cytometry according to ICH Q2(R1)
Authors: T Nicotra, A Desnos, J Halimi, H Antonot, L Reppel, T Belmas, A Freton, F Stranieri, M Mebarki, J Larghero, A Cras, L Faivre
Stem Cell Res Ther, 2020-10-01;11(1):426.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Modeling COVID-19 with Human Pluripotent Stem Cell-Derived Cells Reveals Synergistic Effects of Anti-inflammatory Macrophages with ACE2 Inhibition Against SARS-CoV-2
Authors: F Duan, L Guo, L Yang, Y Han, A Thakur, BE Nilsson-Pa, P Wang, Z Zhang, CY Ma, X Zhou, T Han, T Zhang, X Wang, D Xu, X Duan, J Xiang, HF Tse, C Liao, W Luo, FP Huang, YW Chen, T Evans, RE Schwartz, B tenOever, DD Ho, S Chen, Q Lian, HJ Chen
Res Sq, 2020-09-15;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Androgen receptor signalling in macrophages promotes TREM-1-mediated prostate cancer cell line migration and invasion
Authors: B Cioni, A Zaalberg, JR van Beijnu, MHM Melis, J van Burgst, MJ Muraro, E Hooijberg, D Peters, I Hofland, Y Lubeck, J de Jong, J Sanders, J Vivié, HG van der Po, JP de Boer, AW Griffioen, W Zwart, AM Bergman
Nat Commun, 2020-09-09;11(1):4498.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Mimicry Embedding Facilitates Advanced Neural Network Training for Image-Based Pathogen Detection
Authors: A Yakimovich, M Huttunen, J Samolej, B Clough, N Yoshida, S Mostowy, EM Frickel, J Mercer
mSphere, 2020-09-09;5(5):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Circulating miRNAs Associated with Dysregulated Vascular and Trophoblast Function as Target-Based Diagnostic Biomarkers for Preeclampsia
Authors: S Kim, M Park, JY Kim, T Kim, JY Hwang, KS Ha, MH Won, S Ryoo, YG Kwon, YM Kim
Cells, 2020-08-31;9(9):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Human CD8+ T Cells Exhibit a Shared Antigen Threshold for Different Effector Responses
Authors: E Abu-Shah, N Trendel, P Kruger, J Nguyen, J Pettmann, M Kutuzov, O Dushek
J. Immunol., 2020-08-17;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Thrombomodulin facilitates peripheral nerve regeneration through regulating M1/M2 switching
Authors: TC Huang, HL Wu, SH Chen, YT Wang, CC Wu
J Neuroinflammation, 2020-08-14;17(1):240.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Human GBP1 Differentially Targets Salmonella and Toxoplasma to License Recognition of Microbial Ligands and Caspase-Mediated Death
Authors: D Fisch, B Clough, MC Domart, V Encheva, H Bando, AP Snijders, LM Collinson, M Yamamoto, AR Shenoy, EM Frickel
Cell Rep, 2020-08-11;32(6):108008.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Oxidized Low-Density Lipoprotein Induces Macrophage Production of Prothrombotic Microparticles
Authors: JF Marchini, A Manica, P Crestani, J Dutzmann, EJ Folco, H Weber, P Libby, K Croce
J Am Heart Assoc, 2020-07-31;9(15):e015878.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Insights into the Mechanism of Action of Highly Diluted Biologics
Authors: SA Tarasov, EA Gorbunov, ES Don, AG Emelyanova, AL Kovalchuk, N Yanamala, AS S Schleker, J Klein-Seet, R Groenestei, JP Tafani, P van der Me, OI Epstein
J. Immunol., 2020-07-29;0(0):.
Species: Human
Sample Types: Protein
Applications: Bioassay

Effect of IFN-gamma on the kynurenine/tryptophan ratio in monolayer-cultured keratinocytes and a 3D reconstructed human epidermis model
Authors: A Gustafsson, Z Prgomet, S Jankovskaj, T Ruzgas, J Engblom, L Ohlsson, A Gjörloff W
J. Dermatol. Sci., 2020-07-17;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Modeling Type 1 Diabetes In�Vitro Using Human Pluripotent Stem Cells
Authors: NC Leite, E Sintov, TB Meissner, MA Brehm, DL Greiner, DM Harlan, DA Melton
Cell Rep, 2020-07-14;32(2):107894.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Inflammation Differentially Modulates the Biological Features of Adult Derived Human Liver Stem/Progenitor Cells
Authors: H El-Kehdy, M Najar, J De Kock, DM Agha, V Rogiers, M Merimi, L Lagneaux, EM Sokal, M Najimi
Cells, 2020-07-08;9(7):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Mapping effector genes at lupus GWAS loci using promoter Capture-C in follicular helper T cells
Authors: C Su, ME Johnson, A Torres, RM Thomas, E Manduchi, P Sharma, P Mehra, C Le Coz, ME Leonard, S Lu, KM Hodge, A Chesi, J Pippin, N Romberg, SFA Grant, AD Wells
Nat Commun, 2020-07-03;11(1):3294.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Glycosaminoglycans bind human IL-27 and regulate its activity
Authors: MC Cavé, S Maillard, K Hildenbran, C Mamelonet, MJ Feige, O Devergne
Eur. J. Immunol., 2020-07-02;0(0):.
Species: Human
Sample Types: Protein
Applications: Bioassay

T Cell-Intrinsic IRF5 Regulates T Cell Signaling, Migration, and Differentiation and Promotes Intestinal Inflammation
Authors: J Yan, SP Pandey, BJ Barnes, JR Turner, C Abraham
Cell Rep, 2020-06-30;31(13):107820.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis
Authors: AL Samson, Y Zhang, ND Geoghegan, XJ Gavin, KA Davies, MJ Mlodzianos, LW Whitehead, D Frank, SE Garnish, C Fitzgibbon, A Hempel, SN Young, AV Jacobsen, W Cawthorne, EJ Petrie, MC Faux, K Shield-Art, N Lalaoui, JM Hildebrand, J Silke, KL Rogers, G Lessene, ED Hawkins, JM Murphy
Nat Commun, 2020-06-19;11(1):3151.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Targeting macrophage checkpoint inhibitor SIRPa for anticancer therapy
Authors: J Liu, S Xavy, S Mihardja, S Chen, K Sompalli, D Feng, TS Choi, B Agoram, R Majeti, IL Weissman, JP Volkmer
JCI Insight, 2020-06-18;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Immunity-and-matrix-regulatory cells derived from human embryonic stem cells safely and effectively treat mouse lung injury and fibrosis
Authors: J Wu, D Song, Z Li, B Guo, Y Xiao, W Liu, L Liang, C Feng, T Gao, Y Chen, Y Li, Z Wang, J Wen, S Yang, P Liu, L Wang, Y Wang, L Peng, GN Stacey, Z Hu, G Feng, W Li, Y Huo, R Jin, N Shyh-Chang, Q Zhou, L Wang, B Hu, H Dai, J Hao
Cell Res., 2020-06-16;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Resolvin D1 and D2 inhibit tumour growth and inflammation via modulating macrophage polarization
Authors: K Shan, N Feng, J Cui, S Wang, H Qu, G Fu, J Li, H Chen, X Wang, R Wang, Y Qi, Z Gu, YQ Chen
J. Cell. Mol. Med., 2020-05-29;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Diminished toll-like receptor response in febrile infection-related epilepsy syndrome (FIRES)
Authors: MY Hsieh, JJ Lin, SH Hsia, JL Huang, KW Yeh, KW Chang, WI Lee
Biomed J, 2020-05-29;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Mapping DNA interaction landscapes in psoriasis susceptibility loci highlights KLF4 as a target gene in 9q31
Authors: H Ray-Jones, K Duffus, A McGovern, P Martin, C Shi, J Hankinson, O Gough, A Yarwood, AP Morris, A Adamson, C Taylor, J Ding, VP Gaddi, Y Fu, P Gaffney, G Orozco, RB Warren, S Eyre
BMC Biol., 2020-05-04;18(1):47.
Species: Human
Sample Types:
Applications: Cell Culture

Increase in Efficacy of Checkpoint Inhibition by Cytokine-Induced-Killer Cells as a Combination Immunotherapy for Renal Cancer
Authors: MN Dehno, Y Li, H Weiher, IGH Schmidt-Wo
Int J Mol Sci, 2020-04-27;21(9):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

RIG-I-like receptor activation drives type I IFN and antiviral signaling to limit�Hantaan orthohantavirus replication
Authors: AM Kell, EA Hemann, JB Turnbull, M Gale
PLoS Pathog., 2020-04-24;16(4):e1008483.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Macrophage M2 polarization induced by exosomes from adipose-derived stem cells contributes to the exosomal proangiogenic effect on mouse ischemic hindlimb
Authors: D Zhu, TK Johnson, Y Wang, M Thomas, K Huynh, Q Yang, VC Bond, YE Chen, D Liu
Stem Cell Res Ther, 2020-04-22;11(1):162.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

M1-like macrophages are potent producers of anti-viral interferons and M1-associated marker-positive lung macrophages are decreased during rhinovirus-induced asthma exacerbations
Authors: A Nikonova, M Khaitov, DJ Jackson, S Traub, MB Trujillo-T, DA Kudlay, AS Dvornikov, A Del-Rosari, R Valenta, LA Stanciu, R Khaitov, SL Johnston
EBioMedicine, 2020-04-09;54(0):102734.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

HDAC Inhibitor, CG-745, Enhances the Anti-Cancer Effect of Anti-PD-1 Immune Checkpoint Inhibitor by Modulation of the Immune Microenvironment
Authors: YD Kim, SM Park, HC Ha, AR Lee, H Won, H Cha, S Cho, JM Cho
J Cancer, 2020-04-06;11(14):4059-4072.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Class IIa Histone Deacetylases Drive Toll-like Receptor-Inducible Glycolysis and Macrophage Inflammatory Responses via Pyruvate Kinase M2
Authors: K Das Gupta, MR Shakespear, JEB Curson, AMV Murthy, A Iyer, MP Hodson, D Ramnath, VA Tillu, JB von Pein, RC Reid, K Tunny, DM Hohenhaus, SV Moradi, GM Kelly, T Kobayashi, JH Gunter, AJ Stevenson, W Xu, L Luo, A Jones, WA Johnston, A Blumenthal, K Alexandrov, BM Collins, JL Stow, DP Fairlie, MJ Sweet
Cell Rep, 2020-02-25;30(8):2712-2728.e8.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

The anti-inflammatory potential of cefazolin as common gamma chain cytokine inhibitor
Authors: B ?y?y?ska-G, B Trzaskowsk, M Dutkiewicz, O Zegrocka-S, M Machci?ska, K Bocian, M Kowalewska, K Koziak
Sci Rep, 2020-02-19;10(1):2886.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Anti-PD-1 antibody decreases tumour-infiltrating regulatory T cells
Authors: K Yoshida, M Okamoto, J Sasaki, C Kuroda, H Ishida, K Ueda, H Ideta, T Kamanaka, A Sobajima, T Takizawa, M Tanaka, K Aoki, T Uemura, H Kato, H Haniu, N Saito
BMC Cancer, 2020-01-08;20(1):25.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Hydrogel based protein biochip for parallel detection of biomarkers for diagnosis of a Systemic Inflammatory Response Syndrome (SIRS) in human serum
Authors: A Stumpf, T Brandstett, J Hübner, J Rühe
PLoS ONE, 2019-12-02;14(12):e0225525.
Species: Human
Sample Types: Serum
Applications: ELISA Standard

Mitochondrial mass governs the extent of human T cell senescence
Authors: LA Callender, EC Carroll, EA Bober, AN Akbar, E Solito, SM Henson
Aging Cell, 2019-12-02;0(0):e13067.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Integrated microRNA/mRNA expression profiling of the skin of psoriasis patients
Authors: D Deli?, K Wolk, R Schmid, O Gabrielyan, D Christou, K Rieber, M Rolser, I Jakob, F Wiech, M Griesser, C Wohnhaas, G Kokolakis, E Witte-Händ, P Baum, R Sabat
J. Dermatol. Sci., 2019-11-30;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Mini tryptophanyl-tRNA synthetase is required for a synthetic phenotype in vascular smooth muscle cells induced by IFN-?-mediated beta2-adrenoceptor signaling
Authors: E Biros, CS Moran
Cytokine, 2019-11-28;127(0):154940.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Immunomodulatory properties of photopolymerizable fucoidan and carrageenans
Authors: ML Amin, D Mawad, S Dokos, P Koshy, PJ Martens, CC Sorrell
Carbohydr Polym, 2019-11-28;230(0):115691.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Pro-inflammatory monocyte profile in patients with major depressive disorder and suicide behaviour and how ketamine induces anti-inflammatory M2 macrophages by NMDAR and mTOR
Authors: W Nowak, LN Grendas, LM Sanmarco, IG Estecho, ÁR Arena, N Eberhardt, DE Rodante, MP Aoki, FM Daray, EA Carrera Si, AE Errasti
EBioMedicine, 2019-11-18;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

High glucose environment induces M1 macrophage polarization that impairs keratinocyte migration via TNF-alpha: An important mechanism to delay the diabetic wound healing
Authors: SM Huang, CS Wu, MH Chiu, CH Wu, YT Chang, GS Chen, CE Lan
J. Dermatol. Sci., 2019-11-13;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Complex alternative splicing of human Endonuclease V mRNA, but evidence for only a single protein isoform
Authors: N Berges, MS Nawaz, T Børresdatt, L Hagen, M Bjørås, JK Laerdahl, I Alseth
PLoS ONE, 2019-11-08;14(11):e0225081.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Dynamic lineage priming is driven via direct enhancer regulation by ERK
Authors: WB Hamilton, Y Mosesson, RS Monteiro, KB Emdal, TE Knudsen, C Francavill, N Barkai, JV Olsen, JM Brickman
Nature, 2019-11-06;575(7782):355-360.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

TSG-6 in conditioned media from adipose mesenchymal stem cells protects against visual deficits in mild traumatic brain injury model through neurovascular modulation
Authors: KA Jha, M Pentecost, R Lenin, J Gentry, L Klaic, N Del Mar, A Reiner, CH Yang, LM Pfeffer, N Sohl, R Gangaraju
Stem Cell Res Ther, 2019-11-05;10(1):318.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Extracellular Vesicles Shedding Promotes Melanoma Growth in Response to Chemotherapy
Authors: LNS Andrade, AH Otake, SGB Cardim, FI da Silva, MM Ikoma Saka, TK Furuya, M Uno, FS Pasini, R Chammas
Sci Rep, 2019-10-09;9(1):14482.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Down-regulation of the islet-specific zinc transporter-8 (ZnT8) protects human insulinoma cells against inflammatory stress
Authors: C Merriman, D Fu
J. Biol. Chem., 2019-10-07;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IL-4 and IL-17A Cooperatively Promote Hydrogen Peroxide Production, Oxidative DNA Damage, and Upregulation of Dual Oxidase 2 in Human Colon and Pancreatic Cancer Cells
Authors: Y Wu, MM Konaté, J Lu, H Makhlouf, R Chuaqui, S Antony, JL Meitzler, MJ Difilippan, H Liu, A Juhasz, G Jiang, I Dahan, K Roy, JH Doroshow
J. Immunol., 2019-09-23;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Integrated Transcriptomic, Phenotypic, and Functional Study Reveals Tissue-Specific Immune Properties of Mesenchymal Stromal Cells
Authors: C Ménard, J Dulong, D Roulois, B Hébraud, L Verdière, C Pangault, V Sibut, I Bezier, N Bescher, C Monvoisin, M Gadelorge, N Bertheuil, E Flécher, L Casteilla, P Collas, L Sensebé, P Bourin, N Espagnolle, K Tarte
Stem Cells, 2019-09-10;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Boiling Histotripsy-induced Partial Mechanical Ablation Modulates Tumour Microenvironment by Promoting Immunogenic Cell Death of Cancers
Authors: KJ Pahk, CH Shin, IY Bae, Y Yang, SH Kim, K Pahk, H Kim, SJ Oh
Sci Rep, 2019-06-21;9(1):9050.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy
Authors: M Pascual-Ga, E Bonfill-Te, E Planas-Rig, C Rubio-Pere, R Iurlaro, A Arias, I Cuartas, A Sala-Hojma, L Escudero, F Martínez-R, I Huber-Ruan, P Nuciforo, L Pedrosa, C Marques, I Braña, E Garralda, M Vieito, M Squatrito, E Pineda, F Graus, C Espejo, J Sahuquillo, J Tabernero, J Seoane
Nat Commun, 2019-06-11;10(1):2416.
Species: Human
Sample Types: Organoid
Applications: Bioassay

Inhibitory Effects of a Novel Chrysin-Derivative, CPD 6, on Acute and Chronic Skin Inflammation
Authors: CH Yu, B Suh, I Shin, EH Kim, D Kim, YJ Shin, SY Chang, SH Baek, H Kim, ON Bae
Int J Mol Sci, 2019-05-28;20(11):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Newly defined ABCB5+ dermal mesenchymal stem cells promote healing of chronic iron overload wounds via secretion of interleukin-1 receptor antagonist
Authors: S Vander Bek, JC de Vries, B Meier-Schi, P Meyer, D Jiang, A Sindrilaru, FF Ferreira, A Hainzl, S Schatz, J Muschhamme, NJ Scheurmann, P Kampilafko, AM Seitz, L Dürselen, A Ignatius, MA Kluth, C Ganss, M Wlaschek, K Singh, P Maity, NY Frank, MH Frank, K Scharffett
Stem Cells, 2019-05-13;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Differential modulation of CXCL8 versus CXCL10, by cytokines, PPAR-gamma, or PPAR-alpha agonists, in primary cells from Graves' disease and ophthalmopathy
Authors: SM Ferrari, F Ragusa, SR Paparo, F Nasini, M Nardi, SS Franceschi, P Fallahi, A Antonelli
Autoimmun Rev, 2019-05-04;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

DNA from virulent M. tuberculosis induces TNF-? production and autophagy in M1 polarized macrophages
Authors: A Ruiz, S Guzmán-Bel, LE Carreto-Bi, Y Gonzalez, E Juárez
Microb. Pathog., 2019-05-02;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Autophagy links antimicrobial activity with antigen presentation in Langerhans cells
Authors: AT Dang, RM Teles, PT Liu, A Choi, A Legaspi, EN Sarno, MT Ochoa, K Parvatiyar, G Cheng, M Gilliet, BR Bloom, RL Modlin
JCI Insight, 2019-04-18;4(8):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

microRNA-148a-3p regulates immunosuppression in DNA mismatch repair-deficient colorectal cancer by targeting PD-L1
Authors: M Ashizawa, H Okayama, T Ishigame, AK Thar Min, K Saito, D Ujiie, Y Murakami, T Kikuchi, Y Nakayama, M Noda, T Tada, H Endo, S Fujita, W Sakamoto, M Saito, Z Saze, T Momma, S Ohki, K Mimura, K Kono
Mol. Cancer Res., 2019-03-14;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

APOBEC Mutagenesis and Copy-Number Alterations Are Drivers of Proteogenomic Tumor Evolution and Heterogeneity in Metastatic Thoracic Tumors
Authors: N Roper, S Gao, TK Maity, AR Banday, X Zhang, A Venugopala, CM Cultraro, R Patidar, S Sindiri, AL Brown, A Goncearenc, AR Panchenko, R Biswas, A Thomas, A Rajan, CA Carter, DE Kleiner, SM Hewitt, J Khan, L Prokunina-, U Guha
Cell Rep, 2019-03-05;26(10):2651-2666.e6.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Identification of P2Y receptors involved in oleamide-suppressing inflammatory responses in murine microglia and human dendritic cells
Authors: M Kita, Y Ano, A Inoue, J Aoki
Sci Rep, 2019-02-28;9(1):3135.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

hCMV-Mediated Immune Escape Mechanisms Favor Pathogen Growth and Disturb the Immune Privilege of the Eye
Authors: K Spekker-Bo, CM Ufermann, M Maywald, A Zimmermann, A Domröse, C Woite, W Däubener, SK Eller
Int J Mol Sci, 2019-02-16;20(4):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Preexisting Virus-Specific T Lymphocytes-Mediated Enhancement of Adenovirus Infections to Human Blood CD14+ Cells
Authors: F Feng, J Zhao, P Li, R Li, L Chen, C Sun
Viruses, 2019-02-13;11(2):.
Species: Human
Sample Types:
Applications: Bioassay

Involvement of the Dectin-1 Receptor upon the Effector Mechanisms of Human Phagocytic Cells against Paracoccidioides brasiliensis
Authors: JC de Quaglia, AM Della Cole, TP Gardizani, GG Romagnoli, R Kaneno, LA Dias-Melic
J Immunol Res, 2019-02-06;2019(0):1529189.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Differential expression and regulation of the non-integrin 37/67-kDa laminin receptor on peripheral blood leukocytes of healthy individuals and patients with rheumatoid arthritis
Authors: BA Kane, H An, P Rajasekari, HP McNeil, K Bryant, N Tedla
Sci Rep, 2019-02-04;9(1):1149.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CCL27/CCL28-CCR10 CHEMOKINE SIGNALING MEDIATES MIGRATION OF LYMPHATIC ENDOTHELIAL CELLS
Authors: T Karnezis, R Farnsworth, NC Harris, SP Williams, C Caesar, DJ Byrne, P Herle, ML Macheda, R Shayan, YF Zhang, S Yazar, SJ Takouridis, C Gerard, S Fox, MG Achen, SA Stacker
Cancer Res., 2019-02-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Prioritizing Crohn's disease genes by integrating association signals with gene expression implicates monocyte subsets
Authors: K Gettler, M Giri, E Kenigsberg, J Martin, LS Chuang, NY Hsu, LA Denson, JS Hyams, A Griffiths, JD Noe, WV Crandall, DR Mack, R Kellermaye, C Abraham, G Hoffman, S Kugathasan, JH Cho
Genes Immun., 2019-01-29;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IFN-? and IL-17A differentially influence the response of human macrophages and neutrophils to Pseudomonas aeruginosa infection
Authors: S Muntaka, Y Almuhanna, D Jackson, S Singh, A Afryie-Asa, M Cámara, L Martínez-P
Infect. Immun., 2019-01-24;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Anti-Allergic and Anti-Inflammatory Effects of Kuwanon G and Morusin on MC/9 Mast Cells and HaCaT Keratinocytes
Authors: SE Jin, H Ha, HK Shin, CS Seo
Molecules, 2019-01-11;24(2):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Total HLA Class I Antigen Loss with the Downregulation of Antigen-Processing Machinery Components in Two Newly Established Sarcomatoid Hepatocellular Carcinoma Cell Lines
Authors: WY Lei, SC Hsiung, SH Wen, CH Hsieh, CL Chen, CG Wallace, CC Chang, SK Liao
J Immunol Res, 2018-12-16;2018(0):8363265.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Myeloid-Derived Suppressor Cells Produce IL-10 to Elicit DNMT3b-Dependent IRF8 Silencing to Promote Colitis-Associated Colon Tumorigenesis
Authors: ML Ibrahim, JD Klement, C Lu, PS Redd, W Xiao, D Yang, DD Browning, NM Savage, PJ Buckhaults, HC Morse, K Liu
Cell Rep, 2018-12-11;25(11):3036-3046.e6.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Non-muscle myosin IIA is post-translationally modified by interferon-stimulated gene 15 in breast cancer cells
Authors: E Cruz-Ramos, M Macías-Sil, A Sandoval-H, AC Tecalco-Cr
Int. J. Biochem. Cell Biol., 2018-12-05;107(0):14-26.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Guanylate-Binding Protein 1 Promotes Migration and Invasion of Human Periodontal Ligament Stem Cells
Authors: S Bai, T Chen, X Deng
Stem Cells Int, 2018-11-28;2018(0):6082956.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Interplay between interferon-stimulated gene 15/ISGylation and interferon gamma signaling in breast cancer cells
Authors: AC Tecalco-Cr, CC Cortés-Gon, E Cruz-Ramos, JO Ramírez Ja, AK Romero-Man, M Sosa-Garro
Cell. Signal., 2018-11-27;54(0):91-101.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Nuclear Translocation of Argonaute 2 in Cytokine-Induced Senescence
Authors: M Rentschler, Y Chen, J Pahl, L Soria-Mart, H Braumüller, E Brenner, O Bischof, M Röcken, T Wieder
Cell. Physiol. Biochem., 2018-11-26;51(3):1103-1118.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Detailed Characterization of Early HIV-1 Replication Dynamics in Primary Human Macrophages
Authors: DA Bejarano, MC Puertas, K Börner, J Martinez-P, B Müller, HG Kräusslich
Viruses, 2018-11-10;10(11):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Attenuation of CD47-SIRP? Signal in Cholangiocarcinoma Potentiates Tumor-Associated Macrophage-Mediated Phagocytosis and Suppresses Intrahepatic Metastasis
Authors: K Vaeteewoot, R Kariya, P Pothipan, S Fujikawa, C Pairojkul, S Waraasawap, K Kuwahara, C Wongkham, S Wongkham, S Okada
Transl Oncol, 2018-11-09;12(2):217-225.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

VISTA expressed in tumour cells regulates T cell function
Authors: K Mulati, J Hamanishi, N Matsumura, K Chamoto, N Mise, K Abiko, T Baba, K Yamaguchi, N Horikawa, R Murakami, M Taki, K Budiman, X Zeng, Y Hosoe, M Azuma, I Konishi, M Mandai
Br. J. Cancer, 2018-11-09;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Status of programmed death-ligand 1 expression in sarcomas
Authors: HK Park, M Kim, M Sung, SE Lee, YJ Kim, YL Choi
J Transl Med, 2018-11-06;16(1):303.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Exosomes released from tumor-associated macrophages transfer miRNAs that induce a Treg/Th17 cell imbalance in epithelial ovarian cancer
Authors: J Zhou, X Li, X Wu, T Zhang, Q Zhu, X Wang, H Wang, K Wang, Y Lin, X Wang
Cancer Immunol Res, 2018-11-05;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Functionalization-dependent effects of cellulose nanofibrils on tolerogenic mechanisms of human dendritic cells
Authors: S Tomi?, N Ili?, V Kokol, A Gruden-Mov, D Mihajlovi?, M Beki?, L Sofroni?-M, M ?oli?, D Vu?evi?
Int J Nanomedicine, 2018-10-31;13(0):6941-6960.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IL-38 has an anti-inflammatory action in psoriasis and its expression correlates with disease severity and therapeutic response to anti-IL-17A treatment
Authors: L Mercurio, M Morelli, C Scarponi, EZ Eisenmesse, N Doti, G Pagnanelli, E Gubinelli, C Mazzanti, A Cavani, M Ruvo, CA Dinarello, C Albanesi, S Madonna
Cell Death Dis, 2018-10-30;9(11):1104.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Decreased allergy incidence in children supplemented with E. coli O83:K24:H31 and its possible modes of action
Authors: J Hrdý, K Vlasáková, V ?erný, L Súkeníková, O Novotná, P Petrásková, K Boráková, R Lodinová-Ž, L Kolá?ová, L Prokešová
Eur. J. Immunol., 2018-10-21;0(0):.
Species: Human
Sample Types: Plasma

Co-culture of dendritic cells and cytokine-induced killer cells effectively suppresses liver cancer stem cell growth by inhibiting pathways in the immune system
Authors: T Yang, W Zhang, L Wang, C Xiao, L Wang, Y Gong, D Huang, B Guo, Q Li, Y Xiang, Y Nan
BMC Cancer, 2018-10-16;18(1):984.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

INF-?: A new spotlight in innate immunity against influenza virus infection
Authors: Y Sun, J Jiang, P Tien, W Liu, J Li
Protein Cell, 2018-10-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline
Authors: TJ Bussian, A Aziz, CF Meyer, BL Swenson, JM van Deurse, DJ Baker
Nature, 2018-09-19;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Prolonging culture of primary human keratinocytes isolated from suction blisters with the Rho kinase inhibitor Y-27632
Authors: ED Anderson, I Sastalla, NJ Earland, M Mahnaz, IN Moore, F Otaizo-Car, TG Myers, CA Myles, SK Datta, IA Myles
PLoS ONE, 2018-09-12;13(9):e0198862.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Interferon-gamma inhibits seminal plasma induction of colony stimulating factor 2 in mouse and human reproductive tract epithelial cells
Authors: DJ Sharkey, DJ Glynn, JE Schjenken, KP Tremellen, SA Robertson
Biol. Reprod., 2018-09-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The proto-oncogene Bcl3 induces immune checkpoint PD-L1 expression, mediating proliferation of ovarian cancer cells
Authors: Y Zou, MM Uddin, S Padmanabha, Y Zhu, P Bu, A Vancura, I Vancurova
J. Biol. Chem., 2018-08-22;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Interleukin 4 is inactivated via selective disulfide-bond reduction by extracellular thioredoxin
Authors: NM Plugis, N Weng, Q Zhao, BA Palanski, HT Maecker, A Habtezion, C Khosla
Proc. Natl. Acad. Sci. U.S.A., 2018-08-13;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

ICAM1 expression is induced by proinflammatory cytokines and associated with TLS formation in aggressive breast cancer subtypes
Authors: SL Figenschau, E Knutsen, I Urbarova, C Fenton, B Elston, M Perander, ES Mortensen, KA Fenton
Sci Rep, 2018-08-06;8(1):11720.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Effects of bone marrow-derived mesenchymal stromal cells on gene expression in human alveolar type II cells exposed to TNF-?, IL-1?, and IFN-?
Authors: M Schwede, EM Wilfong, RL Zemans, PJ Lee, C Dos Santos, X Fang, MA Matthay
Physiol Rep, 2018-08-01;6(16):e13831.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

USP17 mediates macrophage-promoted inflammation and stemness in lung cancer cells by regulating TRAF2/TRAF3 complex formation
Authors: CH Lu, DW Yeh, CY Lai, YL Liu, LR Huang, AY Lee, SC Jin, TH Chuang
Oncogene, 2018-07-23;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Tumor innate immunity primed by specific interferon-stimulated endogenous retroviruses
Authors: I Cañadas, R Thummalapa, JW Kim, S Kitajima, RW Jenkins, CL Christense, M Campisi, Y Kuang, Y Zhang, E Gjini, G Zhang, T Tian, DR Sen, D Miao, Y Imamura, T Thai, B Piel, H Terai, AR Aref, T Hagan, S Koyama, M Watanabe, H Baba, AE Adeni, CA Lydon, P Tamayo, Z Wei, M Herlyn, TU Barbie, R Uppaluri, LM Sholl, E Sicinska, J Sands, S Rodig, KK Wong, CP Paweletz, H Watanabe, DA Barbie
Nat. Med., 2018-07-23;0(0):.
Species: Human
Sample Types: Transfected Whole Cells
Applications: Bioassay

Differential Gene Expression Profile of Human Neutrophils Cultured with Plasmodium falciparum-Parasitized Erythrocytes
Authors: MA Terkawi, R Takano, K Kato
J Immunol Res, 2018-07-05;2018(0):6709424.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Proton irradiation orchestrates macrophage reprogramming through NF?B signaling
Authors: G Genard, AC Wera, C Huart, B Le Calve, S Penninckx, A Fattacciol, T Tabarrant, C Demazy, N Ninane, AC Heuskin, S Lucas, C Michiels
Cell Death Dis, 2018-06-27;9(7):728.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Intratumoral delivery of an adenoviral vector carrying the SOCS-1 gene enhances T cell-mediated anti-tumor immunity by suppressing PD-L1
Authors: S Nakagawa, S Serada, R Kakubari, K Hiramatsu, T Sugase, S Matsuzaki, S Matsuzaki, Y Ueda, K Yoshino, T Ohkawara, M Fujimoto, T Kishimoto, T Kimura, T Naka
Mol. Cancer Ther., 2018-06-11;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Neutrophils induce macrophage anti-inflammatory reprogramming by suppressing NF-?B activation
Authors: JA Marwick, R Mills, O Kay, K Michail, J Stephen, AG Rossi, I Dransfield, N Hirani
Cell Death Dis, 2018-06-04;9(6):665.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Interferon-gamma drives programmed death-ligand 1 expression on islet ? cells to limit T cell function during autoimmune diabetes
Authors: KC Osum, AL Burrack, T Martinov, NL Sahli, JS Mitchell, CG Tucker, KE Pauken, K Papas, B Appakalai, JA Spanier, BT Fife
Sci Rep, 2018-05-29;8(1):8295.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Unique and shared inflammatory profiles of human brain endothelia and pericytes
Authors: LCD Smyth, J Rustenhove, TI Park, P Schweder, D Jansson, PA Heppner, SJ O'Carroll, EW Mee, RLM Faull, M Curtis, M Dragunow
J Neuroinflammation, 2018-05-11;15(1):138.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Regulation of fibroblast Fas expression by soluble and mechanical pro-fibrotic stimuli
Authors: AE Dodi, IO Ajayi, C Chang, M Beard, SL Ashley, SK Huang, VJ Thannickal, DJ Tschumperl, TH Sisson, JC Horowitz
Respir. Res., 2018-05-10;19(1):91.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

slan+ monocytes and macrophages mediate CD20-dependent B cell lymphoma elimination via ADCC and ADCP
Authors: W Vermi, A Micheletti, G Finotti, C Tecchio, F Calzetti, S Costa, M Bugatti, S Calza, C Agostinell, S Pileri, P Balzarini, A Tucci, G Rossi, L Furlani, G Todeschini, A Zamò, F Facchetti, L Lorenzi, S Lonardi, MA Cassatella
Cancer Res., 2018-05-10;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Antimycobacterial effect of IFNG (interferon gamma)-induced autophagy is dependent on the HMOX1 (heme oxygenase 1)-mediated increase in the intracellular calcium levels and modulation of PPP3/calcineurin-TFEB (transcription factor EB) axis
Authors: N Singh, P Kansal, Z Ahmad, N Baid, H Kushwaha, N Khatri, A Kumar
Autophagy, 2018-05-10;0(0):1-57.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Metabolic systems analysis of LPS induced endothelial dysfunction applied to sepsis patient stratification
Authors: S McGarrity, Ó Anuforo, H Halldórsso, A Bergmann, S Halldórsso, S Palsson, HH Henriksen, PI Johansson, Ó Rolfsson
Sci Rep, 2018-05-01;8(1):6811.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Class 3 semaphorins modulate the invasive capacity of rheumatoid arthritis fibroblast-like synoviocytes
Authors: MW Tang, B Malvar Fer, SP Newsom, JD van Buul, TRDJ Radstake, DL Baeten, PP Tak, KA Reedquist, S García
Rheumatology (Oxford), 2018-05-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Differentiation, Differentiation

Effects of osteoprotegerin/TNFRSF11B in two models of abdominal aortic aneurysms
Authors: E Vorkapic, A Kunath, D Wågsäter
Mol Med Rep, 2018-04-27;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Effect of colorectal cancer-derived extracellular vesicles on the immunophenotype and cytokine secretion profile of monocytes and macrophages
Authors: I Pop?na, A ?bols, L Saul?te, K Pleiko, E Zandberga, K J?kabsons, E Endzeli?š, A Llorente, A Lin?, U Rieksti?a
Cell Commun. Signal, 2018-04-24;16(1):17.
Species: Human
Sample Types: Whole Cells
Applications: Differentiation, Differentiation

High-Mobility Group Box 1 in Dry Eye Inflammation
Authors: C Lema, RY Reins, RL Redfern
Invest. Ophthalmol. Vis. Sci., 2018-04-01;59(5):1741-1750.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The Absence of Indoleamine 2,3-Dioxygenase Inhibits Retinal Capillary Degeneration in Diabetic Mice
Authors: RB Nahomi, S Sampathkum, AM Myers, L Elghazi, DG Smith, J Tang, CA Lee, TS Kern, RH Nagaraj, PE Fort
Invest. Ophthalmol. Vis. Sci., 2018-04-01;59(5):2042-2053.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Natural Killer Cell Inhibition by HLA-E Molecules on Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelial Cells
Authors: S Sugita, K Makabe, Y Iwasaki, S Fujii, M Takahashi
Invest. Ophthalmol. Vis. Sci., 2018-04-01;59(5):1719-1731.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Carcinoembryonic antigen as a marker of radioresistance in colorectal cancer: a potential role of macrophages
Authors: EY Huang, JC Chang, HH Chen, CY Hsu, HC Hsu, KL Wu
BMC Cancer, 2018-03-27;18(1):321.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Association of NF-E2 Related Factor 2 (Nrf2) and inflammatory cytokines in recent onset Type 2 Diabetes Mellitus
Authors: D Sireesh, U Dhamodhara, K Ezhilarasi, V Vijay, KM Ramkumar
Sci Rep, 2018-03-23;8(1):5126.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The RNA-binding protein MEX3B mediates resistance to cancer immunotherapy by downregulating HLA-A�expression
Authors: L Huang, S Malu, JA McKenzie, MC Andrews, AH Talukder, T Tieu, TV Karpinets, C Haymaker, MA Forget, LJ Williams, Z Wang, R Mbofung, ZQ Wang, RE Davis, RS Lo, JA Wargo, MA Davies, C Bernatchez, TP Heffernan, RN Amaria, A Korkut, W Peng, J Roszik, G Lizee, SE Woodman, P Hwu
Clin. Cancer Res., 2018-03-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The PI3K?-Selective Inhibitor Idelalisib Minimally Interferes with Immune Effector Function Mediated by Rituximab or Obinutuzumab and Significantly Augments B Cell Depletion In Vivo
Authors: A Palazzo, S Herter, L Grosmaire, R Jones, CR Frey, F Limani, M Bacac, P Umana, RJ Oldham, MJE Marshall, KL Cox, AH Turaj, MS Cragg, C Klein, MJ Carter, S Tannheimer
J. Immunol., 2018-02-16;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Beta cell extracellular vesicle miR-21-5p cargo is increased in response to inflammatory cytokines and serves as a biomarker of type 1 diabetes
Authors: AJ Lakhter, RE Pratt, RE Moore, KK Doucette, BF Maier, LA DiMeglio, EK Sims
Diabetologia, 2018-02-14;0(0):.
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Changes in the Anti-Allergic Activities of Sesame by Bioconversion
Authors: TD Jung, SI Choi, SH Choi, BY Cho, WS Sim, SJ Lee, SJ Park, DB Kim, YC Kim, JH Lee, OH Lee
Nutrients, 2018-02-14;10(2):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Pathogen recognition by NK cells amplifies the pro-inflammatory cytokine production of monocyte-derived DC via IFN-?
Authors: T Oth, THPM Habets, WTV Germeraad, MI Zonneveld, GMJ Bos, J Vanderloch
BMC Immunol., 2018-02-13;19(1):8.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1
Authors: CW Li, SO Lim, EM Chung, YS Kim, AH Park, J Yao, JH Cha, W Xia, LC Chan, T Kim, SS Chang, HH Lee, CK Chou, YL Liu, HC Yeh, EP Perillo, AK Dunn, CW Kuo, KH Khoo, JL Hsu, Y Wu, JM Hsu, H Yamaguchi, TH Huang, AA Sahin, GN Hortobagyi, SS Yoo, MC Hung
Cancer Cell, 2018-02-12;33(2):187-201.e10.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Virus-like infection induces human ? cell dedifferentiation
Authors: M Oshima, KP Knoch, M Diedisheim, A Petzold, P Cattan, M Bugliani, P Marchetti, P Choudhary, GC Huang, SR Bornstein, M Solimena, O Albagli-Cu, R Scharfmann
JCI Insight, 2018-02-08;3(3):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MicroRNA-374b inhibits liver cancer progression via down regulating programmed cell death-1 expression on cytokine-induced killer cells
Authors: F Huang, B Wang, J Zeng, S Sang, J Lei, Y Lu
Oncol Lett, 2018-02-05;15(4):4797-4804.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Decreased RNF41 expression leads to insulin resistance in skeletal muscle of obese women
Authors: C Breuker, C Amouzou, O Fabre, K Lambert, P Seyer, A Bourret, T Salehzada, J Mercier, A Sultan, C Bisbal
Metab. Clin. Exp., 2018-02-02;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

RNA-Seq Analysis of IL-1B and IL-36 Responses in Epidermal Keratinocytes Identifies a Shared MyD88-Dependent Gene Signature
Authors: WR Swindell, MA Beamer, MK Sarkar, S Loftus, J Fullmer, X Xing, NL Ward, LC Tsoi, MJ Kahlenberg, Y Liang, JE Gudjonsson
Front Immunol, 2018-01-29;9(0):80.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Trichinella spiralis Excretory-Secretory Products Induce Tolerogenic Properties in Human Dendritic CellsviaToll-Like Receptors 2 and 4
Authors: N Ilic, A Gruden-Mov, J Cvetkovic, S Tomic, DB Vucevic, C Aranzamend, M Colic, E Pinelli, L Sofronic-M
Front Immunol, 2018-01-24;9(0):11.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The IL20 Genetic Polymorphism Is Associated with Altered Clinical Outcome in Septic Shock
Authors: TA Nakada, P Wacharasin, JA Russell, JH Boyd, E Nakada, SA Thair, T Shimada, KR Walley
J Innate Immun, 2018-01-16;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Antigen presentation of the Oct4 and Sox2 peptides by CD154-activated B lymphocytes enhances the killing effect of cytotoxic T lymphocytes on tumor stem-like cells derived from cisplatin-resistant lung cancer cells
Authors: X Zhang, Y Zhang, J Xu, H Wang, X Zheng, Y Lou, B Han
J Cancer, 2018-01-01;9(2):367-374.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Conserved structures formed by heterogeneous RNA sequences drive silencing of an inflammation responsive post-transcriptional operon
Authors: A Basu, N Jain, BS Tolbert, AA Komar, B Mazumder
Nucleic Acids Res., 2017-12-15;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Liraglutide dictates macrophage phenotype in apolipoprotein E null mice during early atherosclerosis
Authors: R Bruen, S Curley, S Kajani, D Crean, ME O'Reilly, MB Lucitt, CG Godson, FC McGillicud, O Belton
Cardiovasc Diabetol, 2017-11-06;16(1):143.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids
Authors: RW Jenkins, AR Aref, PH Lizotte, E Ivanova, S Stinson, CW Zhou, M Bowden, J Deng, H Liu, D Miao, MX He, W Walker, G Zhang, T Tian, C Cheng, Z Wei, S Palakurthi, M Bittinger, H Vitzthum, JW Kim, A Merlino, M Quinn, C Venkataram, JA Kaplan, A Portell, PC Gokhale, B Phillips, A Smart, A Rotem, RE Jones, L Keogh, M Anguiano, L Stapleton, Z Jia, M Barzily-Ro, I Cañadas, TC Thai, MR Hammond, R Vlahos, ES Wang, H Zhang, S Li, GJ Hanna, W Huang, MP Hoang, A Piris, JP Eliane, AO Stemmer-Ra, L Cameron, MJ Su, P Shah, B Izar, M Thakuria, NR LeBoeuf, G Rabinowits, V Gunda, S Parangi, JM Cleary, BC Miller, S Kitajima, R Thummalapa, B Miao, TU Barbie, V Sivathanu, J Wong, WG Richards, R Bueno, CH Yoon, J Miret, M Herlyn, LA Garraway, EM Van Allen, GJ Freeman, PT Kirschmeie, JH Lorch, PA Ott, FS Hodi, KT Flaherty, RD Kamm, GM Boland, KK Wong, D Dornan, CP Paweletz, DA Barbie
Cancer Discov, 2017-11-03;0(0):.
Species: Human, Mouse
Sample Types: Organoids
Applications: Bioassay

IFN-? and TNF-? synergism may provide a link between psoriasis and inflammatory atherogenesis
Authors: NN Mehta, HL Teague, WR Swindell, Y Baumer, NL Ward, X Xing, B Baugous, A Johnston, AA Joshi, J Silverman, DH Barnes, L Wolterink, RP Nair, PE Stuart, M Playford, JJ Voorhees, MK Sarkar, JT Elder, K Gallagher, SK Ganesh, JE Gudjonsson
Sci Rep, 2017-10-23;7(1):13831.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Priming and Activation of Inflammasome by Canarypox Virus Vector ALVAC via the cGAS/IFI16-STING-Type I IFN Pathway and AIM2 Sensor
Authors: F Liu, Q Niu, X Fan, C Liu, J Zhang, Z Wei, W Hou, TD Kanneganti, ML Robb, JH Kim, NL Michael, J Sun, L Soong, H Hu
J. Immunol., 2017-09-25;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

SPI-2/CrmA inhibits IFN-? induction by targeting TBK1/IKK?
Authors: Y Qin, M Li, SL Zhou, W Yin, Z Bian, HB Shu
Sci Rep, 2017-09-05;7(1):10495.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Biological and functional characterization of bone marrow-derived mesenchymal stromal cells from patients affected by primary immunodeficiency
Authors: N Starc, D Ingo, A Conforti, V Rossella, L Tomao, A Pitisci, F De Mattia, I Brigida, M Algeri, M Montanari, G Palumbo, P Merli, P Rossi, A Aiuti, F Locatelli, ME Bernardo
Sci Rep, 2017-08-15;7(1):8153.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Rheumatoid arthritis and psoriatic arthritis synovial fluid stimulates prolactin production by macrophages
Authors: MW Tang, S Garcia, B Malvar Fer, DM Gerlag, PP Tak, KA Reedquist
J. Leukoc. Biol., 2017-06-22;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Mitochondrial DNA depletion induces innate immune dysfunction rescued by interferon-?
Authors: JD Widdringto, A Gomez-Dura, JS Steyn, A Pyle, MH Ruchaud-Sp, J Scott, SV Baudouin, AJ Rostron, J Simpson, PF Chinnery F
J. Allergy Clin. Immunol., 2017-06-17;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A 3D microfluidic model for preclinical evaluation of TCR-engineered T cells against solid tumors
Authors: A Pavesi, AT Tan, S Koh, A Chia, M Colombo, E Antonecchi, C Miccolis, E Ceccarello, G Adriani, MT Raimondi, RD Kamm, A Bertoletti
JCI Insight, 2017-06-15;2(12):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Image based Machine Learning for identification of macrophage subsets
Authors: HM Rostam, PM Reynolds, MR Alexander, N Gadegaard, AM Ghaemmagha
Sci Rep, 2017-06-14;7(1):3521.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

NOX2-dependent ATM kinase activation dictates pro-inflammatory macrophage phenotype and improves effectiveness to radiation therapy
Authors: Q Wu, A Allouch, A Paoletti, C Leteur, C Mirjolet, I Martins, L Voisin, F Law, H Dakhli, E Mintet, M Thoreau, Z Muradova, M Gauthier, O Caron, F Milliat, DM Ojcius, F Rosselli, E Solary, N Modjtahedi, E Deutsch, JL Perfettini
Cell Death Differ., 2017-06-02;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Colony-stimulating factor 1 receptor blockade inhibits tumor growth by altering the polarization of tumor-associated macrophages in hepatocellular carcinoma
Authors: JY Ao, XD Zhu, ZT Chai, H Cai, YY Zhang, KZ Zhang, LQ Kong, N Zhang, BG Ye, DN Ma, HC Sun
Mol. Cancer Ther., 2017-06-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Human Neutrophils Produce CCL23 in Response to Various TLR-Agonists and TNF?
Authors: F Arruda-Sil, F Bianchetto, S Gasperini, S Polletti, E Cosentino, N Tamassia, MA Cassatella
Front Cell Infect Microbiol, 2017-05-12;7(0):176.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Monocytic microRNA profile associated with coronary collateral artery function in chronic total occlusion patients
Authors: N Hakimzadeh, J Elias, GWM Wijntjens, R Theunissen, A van Weert, MW Smulders, N van den Ak, PD Moerland, HJ Verberne, LP Hoebers, JPS Henriques, AM van der La, M Ilhan, M Post, SCAM Bekkers, JJ Piek
Sci Rep, 2017-05-08;7(1):1532.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Psoriatic cutaneous inflammation promotes human monocyte differentiation into active osteoclasts, facilitating bone damage
Authors: A Raimondo, S Lembo, RD Caprio, G Donnarumma, G Monfrecola, N Balato, F Ayala, A Balato
Eur. J. Immunol., 2017-05-02;0(0):.
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay

Differential regulation of surface receptor expression, proliferation, and apoptosis in HaCaT cells stimulated with interferon-?, interleukin-4, tumor necrosis factor-?, or muramyl dipeptide
Authors: E El Darzi, S Bazzi, S Daoud, KS Echtay, GM Bahr
Int J Immunopathol Pharmacol, 2017-04-28;0(0):3946320177076.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Unique molecular profile of exosomes derived from primary human proximal tubular epithelial cells under diseased conditions
Authors: X Wang, R Wilkinson, K Kildey, J Potriquet, J Mulvenna, RJ Lobb, A Möller, N Cloonan, P Mukhopadhy, AJ Kassianos, H Healy
J Extracell Vesicles, 2017-04-21;6(1):1314073.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Salt suppresses IFN? inducible chemokines through the IFN?-JAK1-STAT1 signaling pathway in proximal tubular cells
Authors: Y Arai, D Takahashi, K Asano, M Tanaka, M Oda, SBH Ko, MSH Ko, S Mandai, N Nomura, T Rai, S Uchida, E Sohara
Sci Rep, 2017-04-20;7(0):46580.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Interferon-? Released by Activated CD8(+) T Lymphocytes Impairs the Calcium Resorption Potential of Osteoclasts in Calcified Human Aortic Valves
Authors: E Nagy, Y Lei, E Martínez-M, SC Body, F Schlotter, M Creager, A Assmann, K Khabbaz, P Libby, GK Hansson, E Aikawa
Am. J. Pathol., 2017-04-19;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Interleukin-1 primes human mesenchymal stem cells towards an anti-inflammatory and pro-trophic phenotype in vitro
Authors: E Redondo-Ca, C Cunningham, J Miller, L Martuscell, S Aoulad-Ali, NJ Rothwell, CM Kielty, SM Allan, E Pinteaux
Stem Cell Res Ther, 2017-04-17;8(1):79.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Interferon-? induced insufficient autophagy contributes to p62-dependent apoptosis of epithelial cells in chronic rhinosinusitis with nasal polyps
Authors: BF Wang, PP Cao, ZC Wang, ZY Li, ZZ Wang, J Ma, B Liao, YK Deng, XB Long, K Xu, H Wang, H Wang, M Zeng, X Lu, Z Liu
Allergy, 2017-04-04;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming
Authors: L Tian, A Goldstein, H Wang, H Ching Lo, I Sun Kim, T Welte, K Sheng, LE Dobrolecki, X Zhang, N Putluri, TL Phung, SA Mani, F Stossi, A Sreekumar, MA Mancini, WK Decker, C Zong, MT Lewis, XH Zhang
Nature, 2017-04-03;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Cathepsin S is the major activator of the psoriasis-associated proinflammatory cytokine IL-36?
Authors: JS Ainscough, T Macleod, D McGonagle, R Brakefield, JM Baron, A Alase, M Wittmann, M Stacey
Proc. Natl. Acad. Sci. U.S.A, 2017-03-13;114(13):E2748-E2757.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Cell type-dependent regulation of free ISG15 levels and ISGylation
Authors: AC Tecalco Cr, K Mejía-Barr
J Cell Commun Signal, 2017-03-11;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

VHL promotes immune response against renal cell carcinoma via NF-?B-dependent regulation of VCAM-1
Authors: D Labrousse-, E Martínez-A, M Corral-Esc, R Bienes-Mar, J Berridy, L Serrano-Ov, E Conde, ML García-Ber, JM Giménez-Ba, AS Salinas-Sá, R Sánchez-Pr, M Yao, M Lasa, MJ Calzada
J. Cell Biol, 2017-02-24;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

ErbB4 signaling stimulates pro-inflammatory macrophage apoptosis and limits colonic inflammation
Authors: MA Schumacher, M Hedl, C Abraham, JK Bernard, PR Lozano, JJ Hsieh, D Almohazey, EB Bucar, S Punit, PJ Dempsey, MR Frey
Cell Death Dis, 2017-02-23;8(2):e2622.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Mesenchymal stromal cells as vehicles of tetravalent bispecific Tandab (CD3/CD19) for the treatment of B cell lymphoma combined with IDO pathway inhibitor D-1-methyl-tryptophan
Authors: X Zhang, Y Yang, L Zhang, Y Lu, Q Zhang, D Fan, Y Zhang, Y Zhang, Z Ye, D Xiong
J Hematol Oncol, 2017-02-23;10(1):56.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Th1high in tumor microenvironment is an indicator of poor prognosis for patients with NSCLC
Authors: J Huang, F Shen, H Huang, C Ling, G Zhang
Oncotarget, 2017-02-21;8(8):13116-13125.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Macrophages confer survival signals via CCR1-dependent translational MCL-1 induction in chronic lymphocytic leukemia
Authors: MH van Atteku, S Terpstra, E Slinger, M von Linder, PD Moerland, A Jongejan, AP Kater, E Eldering
Oncogene, 2017-02-13;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Cytosolic DNA Promotes Signal Transducer and Activator of Transcription 3 (STAT3) Phosphorylation by TANK-binding kinase 1 (TBK1) to Restrain STAT3 Activity
Authors: HC Hsia, JE Hutti, AS Baldwin
J. Biol. Chem, 2017-02-10;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Involvement of ?-defensin 130 (DEFB130) in the macrophage microbicidal mechanisms for killing Plasmodium falciparum
Authors: MA Terkawi, R Takano, A Furukawa, F Murakoshi, K Kato
Sci Rep, 2017-02-09;7(0):41772.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Guanylate-binding protein 1 (GBP1) contributes to the immunity of human mesenchymal stromal cells against Toxoplasma gondii
Authors: A Qin, DH Lai, Q Liu, W Huang, YP Wu, X Chen, S Yan, H Xia, G Hide, ZR Lun, FJ Ayala, AP Xiang
Proc. Natl. Acad. Sci. U.S.A, 2017-01-25;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Curcumin induces apoptosis in human leukemic cell lines through an IFIT2-dependent pathway
Authors: Y Zhang, Y Kong, S Liu, L Zeng, L Wan, Z Zhang
Cancer Biol. Ther, 2017-01-10;0(0):1-8.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IFN type I and II induce BAFF secretion from human decidual stromal cells
Authors: AC Lundell, I Nordstr”m, K Andersson, C Lundqvist, E Telemo, S Nava, H Kaipe, A Rudin
Sci Rep, 2017-01-06;7(0):39904.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Mycobacterium tuberculosis ESAT6 and CPF10 Induce Adenosine Deaminase 2 mRNA Expression in Monocyte-Derived Macrophages
Authors: MJ Bae, S Ryu, HJ Kim, SI Cha, CH Kim, J Lee
Tuberc Respir Dis (Seoul), 2016-12-30;80(1):77-82.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Thioredoxin-1 Selectively Activates Transglutaminase 2 in the Extracellular Matrix of the Small Intestine: Implications for Celiac Disease
Authors: Nicholas M Plugis
J. Biol. Chem, 2016-12-21;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Prenylated Polyphenols from Clusiaceae and Calophyllaceae with Immunomodulatory Activity on Endothelial Cells
PLoS ONE, 2016-12-01;11(12):e0167361.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Regulation and function of Bone Morphogenetic Protein signaling in colonic injury and inflammation
Authors: Andrea Todisco
Am. J. Physiol. Gastrointest. Liver Physiol., 2016-11-17;0(0):ajpgi.00169.2.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Fc engineering approaches to enhance the agonism and effector functions of an anti-OX40 antibody
Authors: Mark L Chiu
J. Biol. Chem., 2016-11-17;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Procyanidin A2 Modulates IL-4-Induced CCL26 Production in Human Alveolar Epithelial Cells
Int J Mol Sci, 2016-11-12;17(11):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Duck Tembusu Virus Nonstructural Protein 1 Antagonizes IFN-? Signaling Pathways by Targeting VISA
Authors: Qiyun Zhu
J. Immunol., 2016-11-07;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Interferon-? Promotes Antibody-mediated Fratricide of Acute Myeloid Leukemia Cells
Authors: Susheela Tridandapa
J. Biol. Chem., 2016-10-25;291(49):25656-25666.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MMP8 Is Increased in Lesions and Blood of Acne Inversa Patients: A Potential Link to Skin Destruction and Metabolic Alterations
Authors: Robert Sabat
Mediators Inflamm., 2016-10-23;2016(0):4097574.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Programmed death-ligand 1 (PD-L1) characterization of circulating tumor cells (CTCs) in muscle invasive and metastatic bladder cancer patients
BMC Cancer, 2016-09-22;16(1):744.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Interferon-? blocks signalling through PDGFR? in human brain pericytes
J Neuroinflammation, 2016-09-21;13(1):249.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

TLR3 preconditioning enhances the therapeutic efficacy of umbilical cord mesenchymal stem cells in TNBS-induced colitis via the TLR3-Jagged-1-Notch-1 pathway
Mucosal Immunol, 2016-09-21;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Diverse fates of uracilated HIV-1 DNA during infection of myeloid lineage cells
Elife, 2016-09-20;5(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Gene-expression profiling of different arms of lymphatic vasculature identifies candidates for manipulation of cell traffic
Proc Natl Acad Sci USA, 2016-09-06;113(38):10643-10648.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MiR-146a modulates macrophage polarization in systemic juvenile idiopathic arthritis by targeting INHBA
Mol Immunol, 2016-08-16;77(0):205-212.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Identification of a major epitope by anti-interferon-? autoantibodies in patients with mycobacterial disease
Nat Med, 2016-08-15;0(0):.
Species: Human
Sample Types: Plasma
Applications: Western Blot

PD-1/PD-L1 blockade enhances T cell activity and antitumor efficacy of imatinib in gastrointestinal stromal tumors
Clin Cancer Res, 2016-07-28;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Transcriptional and functional characterization of CD137L-dendritic cells identifies a novel dendritic cell phenotype
Sci Rep, 2016-07-19;6(0):29712.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CD1c-Expression by Monocytes - Implications for the Use of Commercial CD1c+ Dendritic Cell Isolation Kits
Authors: Martine Schrøder
PLoS ONE, 2016-06-16;11(6):e0157387.
Species: Human
Sample Types: Cell Culture Supernates
Applications: Bioassay

Monocyte Differentiation towards Protumor Activity Does Not Correlate with M1 or M2 Phenotypes
Authors: G Karina Chimal-Ram
J Immunol Res, 2016-06-08;2016(0):6031486.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Soluble Siglec-9 suppresses arthritis in a collagen-induced arthritis mouse model and inhibits M1 activation of RAW264.7 macrophages
Authors: Takuya Matsumoto
Arthritis Res Ther, 2016-06-07;18(1):133.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Effective Cytotoxic T Lymphocyte Targeting of Persistent HIV-1 during Antiretroviral Therapy Requires Priming of Naive CD8+ T Cells
Authors: Kellie N Smith
MBio, 2016-05-31;7(3):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Immunomodulation by mesenchymal stem cells in treating human autoimmune disease-associated lung fibrosis
Authors: M Liu, X Zeng, J Wang, Z Fu, J Wang, M Liu, D Ren, B Yu, L Zheng, X Hu, W Shi, J Xu
Stem Cell Res Ther, 2016-04-23;7(1):63.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

B cell IFN-? receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6
Authors: SW Jackson, HM Jacobs, T Arkatkar, EM Dam, NE Scharping, NS Kolhatkar, B Hou, JH Buckner, DJ Rawlings
J Exp Med, 2016-04-11;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Up-Regulation of Human Inducible Nitric Oxide Synthase by p300 Transcriptional Complex.
Authors: Guo Z, Zheng L, Liao X, Geller D
PLoS ONE, 2016-01-11;11(1):e0146640.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IDO Downregulation Induces Sensitivity to Pemetrexed, Gemcitabine, FK866, and Methoxyamine in Human Cancer Cells.
Authors: Maleki Vareki S, Chen D, Di Cresce C, Ferguson P, Figueredo R, Pampillo M, Rytelewski M, Vincent M, Min W, Zheng X, Koropatnick J
PLoS ONE, 2015-11-18;10(11):e0143435.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

PRC2 Epigenetically Silences Th1-Type Chemokines to Suppress Effector T-Cell Trafficking in Colon Cancer.
Authors: Nagarsheth N, Peng D, Kryczek I, Wu K, Li W, Zhao E, Zhao L, Wei S, Frankel T, Vatan L, Szeliga W, Dou Y, Owens S, Marquez V, Tao K, Huang E, Wang G, Zou W
Cancer Res, 2015-11-13;76(2):275-82.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Interferon-gamma Inhibits Ebola Virus Infection.
Authors: Rhein B, Powers L, Rogers K, Anantpadma M, Singh B, Sakurai Y, Bair T, Miller-Hunt C, Sinn P, Davey R, Monick M, Maury W
PLoS Pathog, 2015-11-12;11(11):e1005263.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Sphingosine 1 Phosphate at the Blood Brain Barrier: Can the Modulation of S1P Receptor 1 Influence the Response of Endothelial Cells and Astrocytes to Inflammatory Stimuli?
Authors: Spampinato S, Obermeier B, Cotleur A, Love A, Takeshita Y, Sano Y, Kanda T, Ransohoff R
PLoS ONE, 2015-07-21;10(7):e0133392.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Activated Brain Endothelial Cells Cross-Present Malaria Antigen.
Authors: Howland S, Poh C, Renia L
PLoS Pathog, 2015-06-05;11(6):e1004963.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Mouse pancreatic beta cells express MHC class II and stimulate CD4(+) T cells to proliferate.
Authors: Zhao Y, Scott N, Quah H, Krishnamurthy B, Bond F, Loudovaris T, Mannering S, Kay T, Thomas H
Eur J Immunol, 2015-05-28;45(9):2494-503.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

An Autocrine Cytokine/JAK/STAT-Signaling Induces Kynurenine Synthesis in Multidrug Resistant Human Cancer Cells.
Authors: Campia I, Buondonno I, Castella B, Rolando B, Kopecka J, Gazzano E, Ghigo D, Riganti C
PLoS ONE, 2015-05-08;10(5):e0126159.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Boswellia serrata Preserves Intestinal Epithelial Barrier from Oxidative and Inflammatory Damage.
Authors: Catanzaro D, Rancan S, Orso G, Dall'Acqua S, Brun P, Giron M, Carrara M, Castagliuolo I, Ragazzi E, Caparrotta L, Montopoli M
PLoS ONE, 2015-05-08;10(5):e0125375.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Identification of a nuclear export sequence in the MHC CIITA.
Authors: Chiu E, Gold T, Fettig V, LeVasseur M, Cressman D
J Immunol, 2015-05-06;194(12):6102-11.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

TIM-3/Gal-9 interaction induces IFNgamma-dependent IDO1 expression in acute myeloid leukemia blast cells.
Authors: Folgiero V, Cifaldi L, Li Pira G, Goffredo B, Vinti L, Locatelli F
J Hematol Oncol, 2015-04-16;8(0):36.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Impaired T cell responsiveness to interleukin-6 in hematological patients with invasive aspergillosis.
Authors: Camargo J, Bhimji A, Kumar D, Kaul R, Pavan R, Schuh A, Seftel M, Lipton J, Gupta V, Humar A, Husain S
PLoS ONE, 2015-04-02;10(4):e0123171.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IFN-gamma from lymphocytes induces PD-L1 expression and promotes progression of ovarian cancer.
Authors: Abiko K, Matsumura N, Hamanishi J, Horikawa N, Murakami R, Yamaguchi K, Yoshioka Y, Baba T, Konishi I, Mandai M
Br J Cancer, 2015-03-31;112(9):1501-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment.
Authors: Marquard J, Otter S, Welters A, Stirban A, Fischer A, Eglinger J, Herebian D, Kletke O, Klemen M, Stozer A, Wnendt S, Piemonti L, Kohler M, Ferrer J, Thorens B, Schliess F, Rupnik M, Heise T, Berggren P, Klocker N, Meissner T, Mayatepek E, Eberhard D, Kragl M, Lammert E
Nat Med, 2015-03-16;21(4):363-72.
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay

Epidermal Expression and Regulation of Interleukin-33 during Homeostasis and Inflammation: Strong Species Differences.
Authors: Sundnes O, Pietka W, Loos T, Sponheim J, Rankin A, Pflanz S, Bertelsen V, Sitek J, Hol J, Haraldsen G, Khnykin D
J Invest Dermatol, 2015-03-04;135(7):1771-80.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Granulocyte-macrophage colony stimulatory factor enhances the pro-inflammatory response of interferon-gamma-treated macrophages to Pseudomonas aeruginosa infection.
Authors: Singh S, Barr H, Liu Y, Robins A, Heeb S, Williams P, Fogarty A, Camara M, Martinez-Pomares L
PLoS ONE, 2015-02-23;10(2):e0117447.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Regulation of IL-17A responses in human airway smooth muscle cells by Oncostatin M.
Authors: Kwofie K, Scott M, Rodrigues R, Guerette J, Radford K, Nair P, Richards C
Respir Res, 2015-02-07;16(0):14.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

ChemR23, the receptor for chemerin and resolvin E1, is expressed and functional on M1 but not on M2 macrophages.
Authors: Herova M, Schmid M, Gemperle C, Hersberger M
J Immunol, 2015-01-30;194(5):2330-7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Inhibition of T-cell activation by retinal pigment epithelial cells derived from induced pluripotent stem cells.
Authors: Sugita S, Kamao H, Iwasaki Y, Okamoto S, Hashiguchi T, Iseki K, Hayashi N, Mandai M, Takahashi M
Invest Ophthalmol Vis Sci, 2015-01-20;56(2):1051-62.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The activation status of human macrophages presenting antigen determines the efficiency of Th17 responses.
Authors: Arnold C, Gordon P, Barker R, Wilson H
Immunobiology, 2015-01-01;220(1):10-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Motor, visual and emotional deficits in mice after closed-head mild traumatic brain injury are alleviated by the novel CB2 inverse agonist SMM-189.
Authors: Reiner A, Heldt S, Presley C, Guley N, Elberger A, Deng Y, D'Surney L, Rogers J, Ferrell J, Bu W, Del Mar N, Honig M, Gurley S, Moore B
Int J Mol Sci, 2014-12-31;16(1):758-87.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Disease-associated polymorphisms in ERAP1 do not alter endoplasmic reticulum stress in patients with ankylosing spondylitis.
Authors: Kenna T, Lau M, Keith P, Ciccia F, Costello M, Bradbury L, Low P, Agrawal N, Triolo G, Alessandro R, Robinson P, Thomas G, Brown M
Genes Immun, 2014-11-06;16(1):35-42.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Monitoring the initiation and kinetics of human dendritic cell-induced polarization of autologous naive CD4+ T cells.
Authors: Oth, Tammy, Schnijderberg, Melanie, Senden-Gijsbers, Birgit L, Germeraad, Wilfred, Bos, Gerard M, Vanderlocht, Joris
PLoS ONE, 2014-08-21;9(8):e103725.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Nitric oxide enhances Th9 cell differentiation and airway inflammation.
Authors: Niedbala W, Besnard A, Nascimento D, Donate P, Sonego F, Yip E, Guabiraba R, Chang H, Fukada S, Salmond R, Schmitt E, Bopp T, Ryffel B, Liew F
Nat Commun, 2014-08-07;5(0):4575.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IFN-gamma primes macrophage activation by increasing phosphatase and tensin homolog via downregulation of miR-3473b.
Authors: Wu C, Xue Y, Wang P, Lin L, Liu Q, Li N, Xu J, Cao X
J Immunol, 2014-08-04;193(6):3036-44.

Maresin biosynthesis and identification of maresin 2, a new anti-inflammatory and pro-resolving mediator from human macrophages.
Authors: Deng B, Wang C, Arnardottir H, Li Y, Cheng C, Dalli J, Serhan C
PLoS ONE, 2014-07-18;9(7):e102362.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Annexin V incorporated into influenza virus particles inhibits gamma interferon signaling and promotes viral replication.
Authors: Berri F, Haffar G, Le V, Sadewasser A, Paki K, Lina B, Wolff T, Riteau B
J Virol, 2014-07-16;88(19):11215-28.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The NKG2D ligand ULBP2 is specifically regulated through an invariant chain-dependent endosomal pathway.
Authors: Uhlenbrock F, Hagemann-Jensen M, Kehlet S, Andresen L, Pastorekova S, Skov S
J Immunol, 2014-07-14;193(4):1654-65.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A role for human brain pericytes in neuroinflammation.
Authors: Jansson D, Rustenhoven J, Feng S, Hurley D, Oldfield R, Bergin P, Mee E, Faull R, Dragunow M
J Neuroinflammation, 2014-06-11;11(0):104.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Hemin controls T cell polarization in sickle cell alloimmunization.
Authors: Zhong H, Bao W, Friedman D, Yazdanbakhsh K
J Immunol, 2014-05-30;193(1):102-10.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Transcriptional regulation of Munc13-4 expression in cytotoxic lymphocytes is disrupted by an intronic mutation associated with a primary immunodeficiency.
Authors: Cichocki F, Schlums H, Li H, Stache V, Holmes T, Lenvik T, Chiang S, Miller J, Meeths M, Anderson S, Bryceson Y
J Exp Med, 2014-05-19;211(6):1079-91.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Skin-resident T cells sense ultraviolet radiation-induced injury and contribute to DNA repair.
Authors: MacLeod A, Rudolph R, Corriden R, Ye I, Garijo O, Havran W
J Immunol, 2014-05-07;192(12):5695-702.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The SLE transcriptome exhibits evidence of chronic endotoxin exposure and has widespread dysregulation of non-coding and coding RNAs.
Authors: Shi L, Zhang Z, Yu A, Wang W, Wei Z, Akhter E, Maurer K, Costa Reis P, Song L, Petri M, Sullivan K
PLoS ONE, 2014-05-05;9(5):e93846.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

E2F1 renders prostate cancer cell resistant to ICAM-1 mediated antitumor immunity by NF-kappaB modulation.
Authors: Ren Z, Kang W, Wang L, Sun B, Ma J, Zheng C, Sun J, Tian Z, Yang X, Xiao W
Mol Cancer, 2014-04-17;13(0):84.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Human adipose-derived stromal/stem cells induce functional CD4+CD25+FoxP3+CD127- regulatory T cells under low oxygen culture conditions.
Authors: Frazier T, McLachlan J, Gimble J, Tucker H, Rowan B
Stem Cells Dev, 2014-03-11;23(9):968-77.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Eosinophils regulate peripheral B cell numbers in both mice and humans.
Authors: Wong, Tina W, Doyle, Alfred D, Lee, James J, Jelinek, Diane F
J Immunol, 2014-03-10;192(8):3548-58.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression.
Authors: Fairfax B, Humburg P, Makino S, Naranbhai V, Wong D, Lau E, Jostins L, Plant K, Andrews R, McGee C, Knight J
Science, 2014-03-07;343(6175):1246949.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MicroRNA-155 negatively affects blood-brain barrier function during neuroinflammation.
Authors: Lopez-Ramirez M, Wu D, Pryce G, Simpson J, Reijerkerk A, King-Robson J, Kay O, de Vries H, Hirst M, Sharrack B, Baker D, Male D, Michael G, Romero I
FASEB J, 2014-03-06;28(6):2551-65.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IL-17 induces an expanded range of downstream genes in reconstituted human epidermis model.
Authors: Chiricozzi, Andrea, Nograles, Kristine, Johnson-Huang, Leanne M, Fuentes-Duculan, Judilyn, Cardinale, Irma, Bonifacio, Kathleen, Gulati, Nicholas, Mitsui, Hiroshi, Guttman-Yassky, Emma, Suarez-Farinas, Mayte, Krueger, James G
PLoS ONE, 2014-02-28;9(2):e90284.
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay

A GM-CSF/IL-33 pathway facilitates allergic airway responses to sub-threshold house dust mite exposure.
Authors: Llop-Guevara A, Chu D, Walker T, Goncharova S, Fattouh R, Silver J, Moore C, Xie J, O'Byrne P, Coyle A, Kolbeck R, Humbles A, Stampfli M, Jordana M
PLoS ONE, 2014-02-14;9(2):e88714.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Rapid healing of cutaneous leishmaniasis by high-frequency electrocauterization and hydrogel wound care with or without DAC N-055: a randomized controlled phase IIa trial in Kabul.
Authors: Jebran A, Schleicher U, Steiner R, Wentker P, Mahfuz F, Stahl H, Amin F, Bogdan C, Stahl K
PLoS Negl Trop Dis, 2014-02-13;8(2):e2694.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

An airway epithelial iNOS-DUOX2-thyroid peroxidase metabolome drives Th1/Th2 nitrative stress in human severe asthma.
Authors: Voraphani N, Gladwin M, Contreras A, Kaminski N, Tedrow J, Milosevic J, Bleecker E, Meyers D, Ray A, Ray P, Erzurum S, Busse W, Zhao J, Trudeau J, Wenzel S
Mucosal Immunol, 2014-02-12;7(5):1175-85.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

cmvIL-10 stimulates the invasive potential of MDA-MB-231 breast cancer cells.
Authors: Valle Oseguera, Cendy A, Spencer, Juliet V
PLoS ONE, 2014-02-10;9(2):e88708.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

No major role for insulin-degrading enzyme in antigen presentation by MHC molecules.
Authors: Culina S, Mauvais F, Hsu H, Burgevin A, Guenette S, Moser A, van Endert P
PLoS ONE, 2014-02-07;9(2):e88365.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CD24-triggered caspase-dependent apoptosis via mitochondrial membrane depolarization and reactive oxygen species production of human neutrophils is impaired in sepsis.
Authors: Parlato M, Souza-Fonseca-Guimaraes F, Philippart F, Misset B, Adib-Conquy M, Cavaillon J
J Immunol, 2014-02-05;192(5):2449-59.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Enriched protein screening of human bone marrow mesenchymal stromal cell secretions reveals MFAP5 and PENK as novel IL-10 modulators.
Authors: Milwid, Jack M, Elman, Jessica, Li, Matthew, Shen, Keyue, Manrai, Arjun, Gabow, Aaron, Yarmush, Joshua, Jiao, Yunxin, Fletcher, Anne, Lee, Jungwoo, Cima, Michael, Yarmush, Martin L, Parekkadan, Biju
Mol Ther, 2014-02-05;22(5):999-1007.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Transcriptomic profiling of the development of the inflammatory response in human monocytes in vitro.
Authors: Italiani, Paola, Mazza, Emilia M, Lucchesi, Davide, Cifola, Ingrid, Gemelli, Claudia, Grande, Alexis, Battaglia, Cristina, Bicciato, Silvio, Boraschi, Diana
PLoS ONE, 2014-02-03;9(2):e87680.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Increased metabolite levels of glycolysis and pentose phosphate pathway in rabbit atherosclerotic arteries and hypoxic macrophage.
Authors: Yamashita A, Zhao Y, Matsuura Y, Yamasaki K, Moriguchi-Goto S, Sugita C, Iwakiri T, Okuyama N, Koshimoto C, Kawai K, Tamaki N, Zhao S, Kuge Y, Asada Y
PLoS ONE, 2014-01-23;9(1):e86426.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The productive entry pathway of HIV-1 in macrophages is dependent on endocytosis through lipid rafts containing CD4.
Authors: van Wilgenburg, Bonnie, Moore, Michael, James, William, Cowley, Sally A
PLoS ONE, 2014-01-22;9(1):e86071.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

TRIM38 inhibits TNFalpha- and IL-1beta-triggered NF-kappaB activation by mediating lysosome-dependent degradation of TAB2/3.
Authors: Hu M, Yang Q, Zhang J, Liu S, Zhang Y, Lin H, Huang Z, Wang Y, Zhang X, Zhong B, Shu H
Proc Natl Acad Sci U S A, 2014-01-13;111(4):1509-14.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

G protein-coupled bile acid receptor 1 stimulation mediates arterial vasodilation through a K(Ca)1.1 (BK(Ca))-dependent mechanism.
Authors: Fryer, Ryan M, Ng, Khing Jo, Nodop Mazurek, Suzanne, Patnaude, Lori, Skow, Donna J, Muthukumarana, Akalushi, Gilpin, Kyle E, Dinallo, Roger M, Kuzmich, Daniel, Lord, John, Sanyal, Sulagna, Yu, Hui, Harcken, Christia, Cerny, Matthew, Hickey, Eugene R, Modis, Louise K
J Pharmacol Exp Ther, 2014-01-07;348(3):421-31.
Species: Human
Sample Types: Plasma
Applications: Bioassay

Cytokines alter IgA1 O-glycosylation by dysregulating C1GalT1 and ST6GalNAc-II enzymes.
Authors: Suzuki, Hitoshi, Raska, Milan, Yamada, Koshi, Moldoveanu, Zina, Julian, Bruce A, Wyatt, Robert J, Tomino, Yasuhiko, Gharavi, Ali G, Novak, Jan
J Biol Chem, 2014-01-07;289(8):5330-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Tie2 signaling cooperates with TNF to promote the pro-inflammatory activation of human macrophages independently of macrophage functional phenotype.
Authors: Garcia S, Krausz S, Ambarus C, Fernandez B, Hartkamp L, van Es I, Hamann J, Baeten D, Tak P, Reedquist K
PLoS ONE, 2014-01-03;9(1):e82088.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

slanDCs selectively accumulate in carcinoma-draining lymph nodes and marginate metastatic cells.
Authors: Vermi W, Micheletti A, Lonardi S, Costantini C, Calzetti F, Nascimbeni R, Bugatti M, Codazzi M, Pinter P, Schakel K, Tamassia N, Cassatella M
Nat Commun, 2014-01-01;5(0):3029.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Identification of novel human leukocyte antigen-A*0201-restricted, cytotoxic T lymphocyte epitopes on CD133 for cancer stem cell immunotherapy.
Authors: Ji, Jianfei, Judkowski, Valeria, Liu, Gentao, Wang, Hongqian, Bunying, Alcinett, Li, Zhenhua, Xu, Minlin, Bender, James, Pinilla, Clemenci, Yu, John S
Stem Cells Transl Med, 2013-12-27;3(3):356-64.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The impact of viral evolution and frequency of variant epitopes on primary and memory human immunodeficiency virus type 1-specific CD8(+) T cell responses.
Authors: Melhem N, Smith K, Huang X, Colleton B, Jiang W, Mailliard R, Mullins J, Rinaldo C
Virology, 2013-12-20;450(0):34-48.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Therapeutic efficacy of suppressing the Jak/STAT pathway in multiple models of experimental autoimmune encephalomyelitis.
Authors: Liu Y, Holdbrooks A, De Sarno P, Rowse A, Yanagisawa L, McFarland B, Harrington L, Raman C, Sabbaj S, Benveniste E, Qin H
J Immunol, 2013-12-09;192(1):59-72.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Conditioned media from macrophages of M1, but not M2 phenotype, inhibit the proliferation of the colon cancer cell lines HT-29 and CACO-2.
Authors: Engstrom A, Erlandsson A, Delbro D, Wijkander J
Int J Oncol, 2013-12-02;44(2):385-92.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CD14 mediates Toll-like receptor 4 (TLR4) endocytosis and spleen tyrosine kinase (Syk) and interferon regulatory transcription factor 3 (IRF3) activation in epithelial cells and impairs neutrophil infiltration and Pseudomonas aeruginosa killing in vivo.
Authors: Roy S, Karmakar M, Pearlman E
J Biol Chem, 2013-11-25;289(2):1174-82.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Cyclooxygenase-2 (COX-2) inhibition constrains indoleamine 2,3-dioxygenase 1 (IDO1) activity in acute myeloid leukaemia cells.
Authors: Iachininoto M, Nuzzolo E, Bonanno G, Mariotti A, Procoli A, Locatelli F, De Cristofaro R, Rutella S
Molecules, 2013-08-22;18(9):10132-45.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Proinflammatory stimuli induce galectin-9 in human mesenchymal stromal cells to suppress T-cell proliferation.
Authors: Gieseke F, Kruchen A, Tzaribachev N, Bentzien F, Dominici M, Muller I
Eur J Immunol, 2013-07-23;43(10):2741-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Therapeutical potential of a peptide mimicking the SOCS1 kinase inhibitory region in skin immune responses.
Authors: Madonna S, Scarponi C, Doti N, Carbone T, Cavani A, Scognamiglio P, Marasco D, Albanesi C
Eur J Immunol, 2013-05-28;43(7):1883-95.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Interleukin-22 binding protein (IL-22BP) is constitutively expressed by a subset of conventional dendritic cells and is strongly induced by retinoic acid.
Authors: Martin J, Beriou G, Heslan M, Chauvin C, Utriainen L, Aumeunier A, Scott C, Mowat A, Cerovic V, Houston S, Leboeuf M, Hubert F, Hemont C, Merad M, Milling S, Josien R
Mucosal Immunol, 2013-05-08;7(1):101-13.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

TGR5 signalling inhibits the production of pro-inflammatory cytokines by in vitro differentiated inflammatory and intestinal macrophages in Crohn's disease.
Authors: Yoneno K, Hisamatsu T, Shimamura K, Kamada N, Ichikawa R, Kitazume M, Mori M, Uo M, Namikawa Y, Matsuoka K, Sato T, Koganei K, Sugita A, Kanai T, Hibi T
Immunology, 2013-05-01;139(1):19-29.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Anti-CD70 immunocytokines for exploitation of interferon-gamma-induced RIP1-dependent necrosis in renal cell carcinoma.
Authors: Chen P, Nogusa S, Thapa R, Shaller C, Simmons H, Peri S, Adams G, Balachandran S
PLoS ONE, 2013-04-17;8(4):e61446.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IL-17 stimulates differentiation of human anti-inflammatory macrophages and phagocytosis of apoptotic neutrophils in response to IL-10 and glucocorticoids.
Authors: Zizzo G, Cohen P
J Immunol, 2013-04-17;190(10):5237-46.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The internal architecture of leukocyte lipid body organelles captured by three-dimensional electron microscopy tomography.
Authors: Melo, Rossana, Paganoti, Guillher, Dvorak, Ann M, Weller, Peter F
PLoS ONE, 2013-03-26;8(3):e59578.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Anti-GM-CSF autoantibodies in patients with cryptococcal meningitis.
Authors: Rosen L, Freeman A, Yang L, Jutivorakool K, Olivier K, Angkasekwinai N, Suputtamongkol Y, Bennett J, Pyrgos V, Williamson P, Ding L, Holland S, Browne S
J Immunol, 2013-03-18;190(8):3959-66.
Species: Human
Sample Types: Plasma
Applications: Bioassay

Inhibition of hepatitis B virus gene expression and replication by ribonuclease P.
Authors: Xia, Chuan, Chen, Yuan-Chu, Gong, Hao, Zeng, Wenbo, Vu, Gia-Phon, Trang, Phong, Lu, Sangwei, Wu, Jianguo, Liu, Fenyong
Mol Ther, 2013-03-12;21(5):995-1003.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Loss of methylation at the IFNG promoter and CNS-1 is associated with the development of functional IFN-gamma memory in human CD4(+) T lymphocytes.
Authors: Dong J, Chang H, Ivascu C, Qian Y, Rezai S, Okhrimenko A, Cosmi L, Maggi L, Eckhardt F, Wu P, Sieper J, Alexander T, Annunziato F, Gossen M, Li J, Radbruch A, Thiel A
Eur J Immunol, 2013-03-01;43(3):793-804.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

STAT2 deficiency and susceptibility to viral illness in humans.
Authors: Hambleton, Sophie, Goodbourn, Stephen, Young, Dan F, Dickinson, Paul, Mohamad, Siti M B, Valappil, Manoj, McGovern, Naomi, Cant, Andrew J, Hackett, Scott J, Ghazal, Peter, Morgan, Neil V, Randall, Richard
Proc Natl Acad Sci U S A, 2013-02-07;110(8):3053-8.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Differential regulation of interleukin-12 (IL-12)/IL-23 by Tim-3 drives T(H)17 cell development during hepatitis C virus infection.
Authors: Wang, Jia M, Shi, Lei, Ma, Cheng J, Ji, Xiao J, Ying, Ruo S, Wu, Xiao Y, Wang, Ke S, Li, Guangyu, Moorman, Jonathan, Yao, Zhi Q
J Virol, 2013-02-06;87(8):4372-83.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Susceptibility-associated genetic variation at IL12B enhances Th1 polarization in psoriasis.
Authors: Johnston A, Xing X, Swindell W, Kochkodan J, Riblett M, Nair R, Stuart P, Ding J, Voorhees J, Elder J, Gudjonsson J
Hum Mol Genet, 2013-01-31;22(9):1807-15.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CDK8 kinase phosphorylates transcription factor STAT1 to selectively regulate the interferon response.
Authors: Bancerek J, Poss Z, Steinparzer I, Sedlyarov V, Pfaffenwimmer T, Mikulic I, Dolken L, Strobl B, Muller M, Taatjes D, Kovarik P
Immunity, 2013-01-24;38(2):250-62.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

p38alpha senses environmental stress to control innate immune responses via mechanistic target of rapamycin.
Authors: Katholnig K, Kaltenecker C, Hayakawa H, Rosner M, Lassnig C, Zlabinger G, Gaestel M, Muller M, Hengstschlager M, Horl W, Park J, Saemann M, Weichhart T
J Immunol, 2013-01-11;190(4):1519-27.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Indoleamine 2,3-dioxygenase 1 (IDO1) activity correlates with immune system abnormalities in multiple myeloma.
Authors: Bonanno G, Mariotti A, Procoli A, Folgiero V, Natale D, De Rosa L, Majolino I, Novarese L, Rocci A, Gambella M, Ciciarello M, Scambia G, Palumbo A, Locatelli F, De Cristofaro R, Rutella S
J Transl Med, 2012-12-11;10(0):247.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IL-22 suppresses IFN-gamma-mediated lung inflammation in asthmatic patients.
Authors: Pennino D, Bhavsar P, Effner R, Avitabile S, Venn P, Quaranta M, Marzaioli V, Cifuentes L, Durham S, Cavani A, Eyerich K, Chung K, Schmidt-Weber C, Eyerich S
J Allergy Clin Immunol, 2012-11-19;131(2):562-70.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Identification of Axl as a downstream effector of TGF-beta1 during Langerhans cell differentiation and epidermal homeostasis.
J. Exp. Med., 2012-10-15;209(11):2033-47.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Mycobacterium tuberculosis infection and tissue factor expression in macrophages.
Authors: Kothari H, Rao L, Vankayalapati R, Pendurthi U
PLoS ONE, 2012-09-24;7(9):e45700.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Engulfment of hematopoietic stem cells caused by down-regulation of CD47 is critical in the pathogenesis of hemophagocytic lymphohistiocytosis.
Authors: Kuriyama T, Takenaka K, Kohno K, Yamauchi T, Daitoku S, Yoshimoto G, Kikushige Y, Kishimoto J, Abe Y, Harada N, Miyamoto T, Iwasaki H, Teshima T, Akashi K
Blood, 2012-09-18;120(19):4058-67.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Efficient clearance of early apoptotic cells by human macrophages requires M2c polarization and MerTK induction.
Authors: Zizzo G, Hilliard B, Monestier M, Cohen P
J Immunol, 2012-08-31;189(7):3508-20.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CD34-derived dendritic cells transfected ex vivo with HIV-Gag mRNA induce polyfunctional T-cell responses in nonhuman primates.
Eur. J. Immunol., 2012-07-04;42(8):2019-30.
Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
Sample Types: Whole Cells
Applications: Bioassay

The SDF-1α/CXCR4 Axis is Required for Proliferation and Maturation of Human Fetal Pancreatic Endocrine Progenitor Cells.
Authors: Kayali AG, Lopez AD, Hao E, Hinton A, Hayek A, King CC
PLoS ONE, 2012-06-22;7(6):e38721.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The C-type Lectin Receptor CLECSF8 (CLEC4D) Is Expressed by Myeloid Cells and Triggers Cellular Activation through Syk Kinase.
Authors: Graham LM, Gupta V, Schafer G, Reid DM, Kimberg M, Dennehy KM, Hornsell WG, Guler R, Campanero-Rhodes MA, Palma AS, Feizi T, Kim SK, Sobieszczuk P, Willment JA, Brown GD
J. Biol. Chem., 2012-06-11;287(31):25964-74.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Regulation of IL-33 expression by IFN-gamma and tumor necrosis factor-alpha in normal human epidermal keratinocytes.
J. Invest. Dermatol., 2012-06-07;132(11):2593-600.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Pentraxin 3 (PTX3) expression in allergic asthmatic airways: role in airway smooth muscle migration and chemokine production.
Authors: Zhang J, Shan L, Koussih L, Redhu NS, Halayko AJ, Chakir J, Gounni AS
PLoS ONE, 2012-04-18;7(4):e34965.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Cross-presentation of tumour antigens by human induced pluripotent stem cell-derived CD141(+)XCR1+ dendritic cells.
Gene Ther, 2011-11-10;19(10):1035-40.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Expression and regulation of CCL15 by human airway smooth muscle cells.
Authors: Joubert P, Lajoie-Kadoch S, Wellemans V, Létuvé S, Tulic MK, Halayko AJ, Hamid Q
Clin. Exp. Allergy, 2011-11-09;42(1):85-94.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Natural killer cell-produced IFN-gamma and TNF-alpha induce target cell cytolysis through up-regulation of ICAM-1.
Authors: Wang R, Jaw JJ, Jaw J, Stutzman NC, Stutzman N, Zou Z, Sun PD
J Leukoc Biol, 2011-11-01;91(2):299-309.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Inter-regulation of Th17 cytokines and the IL-36 cytokines in vitro and in vivo: implications in psoriasis pathogenesis.
Authors: Carrier Y, Ma HL, Ramon HE, Napierata L, Small C, O'Toole M, Young DA, Fouser LA, Nickerson-Nutter C, Collins M, Dunussi-Joannopoulos K, Medley QG
J. Invest. Dermatol., 2011-09-01;131(12):2428-37.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Identification of IDO-positive and IDO-negative human dendritic cells after activation by various proinflammatory stimuli.
Authors: Von Bubnoff D, Scheler M, Wilms H, Fimmers R, Bieber T
J. Immunol., 2011-05-04;186(12):6701-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Human cytomegalovirus IE1 protein elicits a type II interferon-like host cell response that depends on activated STAT1 but not interferon-gamma.
Authors: Knoblach T, Grandel B, Seiler J, Nevels M, Paulus C
PLoS Pathog., 2011-04-14;7(4):e1002016.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Epigenetic modulation enhances the therapeutic effect of anti-IL-13R alpha2 antibody in human mesothelioma xenografts.
Clin. Cancer Res., 2011-02-28;17(9):2819-29.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Native IL-32 is released from intestinal epithelial cells via a non-classical secretory pathway as a membrane-associated protein.
Authors: Hasegawa H, Thomas HJ, Schooley K, Born TL
Cytokine, 2011-01-01;53(1):74-83.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Bacterial lipoprotein TLR2 agonists broadly modulate endothelial function and coagulation pathways in vitro and in vivo.
Authors: Shin HS, Xu F, Bagchi A, Herrup E, Wilhelmsen K
J. Immunol., 2010-12-17;186(2):1119-30.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Xanthine oxidoreductase promotes the inflammatory state of mononuclear phagocytes through effects on chemokine expression, peroxisome proliferator-activated receptor-gamma sumoylation, and HIF-1alpha.
Authors: Gibbings S, Elkins ND, Fitzgerald H, Tiao J, Weyman ME, Shibao G, Fini MA, Wright RM
J. Biol. Chem., 2010-11-08;286(2):961-75.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IL-16 promotes T. whipplei replication by inhibiting phagosome conversion and modulating macrophage activation.
Authors: Ghigo E, Barry AO, Pretat L, Al Moussawi K, Desnues B, Capo C, Kornfeld H, Mege JL
PLoS ONE, 2010-10-21;5(10):e13561.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

B7-h3 augments the inflammatory response and is associated with human sepsis.
Authors: Zhang G, Wang J, Kelly J
J. Immunol., 2010-08-09;185(6):3677-84.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Systematic cytokine receptor profiling reveals GM-CSF as a novel TLR-independent activator of human plasmacytoid predendritic cells.
Authors: Ghirelli C, Zollinger R, Soumelis V
Blood, 2010-04-09;115(24):5037-40.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Evidence for altered Wnt signaling in psoriatic skin.
Authors: Gudjonsson JE, Johnston A, Stoll SW
J. Invest. Dermatol., 2010-04-08;130(7):1849-59.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IL-17 amplifies human contact hypersensitivity by licensing hapten nonspecific Th1 cells to kill autologous keratinocytes.
Authors: Pennino D, Eyerich K, Scarponi C, Carbone T, Eyerich S, Nasorri F, Garcovich S, Traidl-Hoffmann C, Albanesi C, Cavani A
J. Immunol., 2010-03-31;184(9):4880-8.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in hepatitis C infection.
Authors: Mengshol JA, Golden-Mason L, Arikawa T
PLoS ONE, 2010-03-04;5(3):e9504.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Creation of a LIGHT mutant with the capacity to evade the decoy receptor for cancer therapy.
Authors: Morishige T, Yoshioka Y, Inakura H, Tanabe A, Yao X, Tsunoda S, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S
Biomaterials, 2010-02-01;31(12):3357-63.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Expression of interleukin 1-like cytokine interleukin 33 and its receptor complex (ST2L and IL1RAcP) in human pancreatic myofibroblasts.
Authors: Nishida A, Andoh A, Imaeda H, Inatomi O, Shiomi H, Fujiyama Y
Gut, 2009-12-08;59(4):531-41.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: a novel immunological cascade with potential relevance in psoriasis.
Authors: Wolk K, Witte E, Warszawska K, Schulze-Tanzil G, Witte K, Philipp S, Kunz S, Docke WD, Asadullah K, Volk HD, Sterry W, Sabat R
Eur. J. Immunol., 2009-12-01;39(12):3570-81.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A novel role for constitutively expressed epithelial-derived chemokines as antibacterial peptides in the intestinal mucosa.
Authors: Kotarsky K, Sitnik KM, Stenstad H, Kotarsky H, Schmidtchen A, Koslowski M, Wehkamp J, Agace WW
Mucosal Immunol, 2009-10-07;3(1):40-8.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Despite IFN-lambda receptor expression, blood immune cells, but not keratinocytes or melanocytes, have an impaired response to type III interferons: implications for therapeutic applications of these cytokines.
Authors: Witte K, Gruetz G, Volk HD, Looman AC, Asadullah K, Sterry W, Sabat R, Wolk K
Genes Immun., 2009-10-01;10(8):702-14.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors.
Authors: Babelova A, Moreth K, Tsalastra-Greul W, Zeng-Brouwers J, Eickelberg O, Young MF, Bruckner P, Pfeilschifter J, Schaefer RM, Schaefer R, Grone HJ, Schaefer L
J Biol Chem, 2009-07-15;284(36):24035-48.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Interferon-beta treatment in multiple sclerosis attenuates inflammatory gene expression through inducible activity of the phosphatase SHP-1.
Authors: Christophi GP, Panos M, Hudson CA, Tsikkou C, Mihai C, Mejico LJ, Jubelt B, Massa PT
Clin. Immunol., 2009-06-25;133(1):27-44.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Interleukin-32 expression in the pancreas.
Authors: Nishida A, Andoh A, Inatomi O, Fujiyama Y
J. Biol. Chem., 2009-04-21;284(26):17868-76.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Interferon-gamma down-regulates NKG2D ligand expression and impairs the NKG2D-mediated cytolysis of MHC class I-deficient melanoma by natural killer cells.
Authors: Schwinn N, Vokhminova D, Sucker A, Textor S, Striegel S, Moll I, Nausch N, Tuettenberg J, Steinle A, Cerwenka A, Schadendorf D, Paschen A
Int. J. Cancer, 2009-04-01;124(7):1594-604.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells.
Authors: Eid RE, Rao DA, Zhou J, Lo SF, Ranjbaran H, Gallo A, Sokol SI, Pfau S, Pober JS, Tellides G
Circulation, 2009-03-02;119(10):1424-32.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Vascular endothelial growth factor induces protein kinase D-dependent production of proinflammatory cytokines in endothelial cells.
Authors: Hao Q, Wang L, Tang H
Am. J. Physiol., Cell Physiol., 2009-01-28;296(4):C821-7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Erythropoietin inhibits respiratory epithelial cell apoptosis in a model of acute lung injury.
Authors: MacRedmond R, Singhera GK, Dorscheid DR
Eur. Respir. J., 2009-01-22;33(6):1403-14.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Human corneal epithelium-derived thymic stromal lymphopoietin links the innate and adaptive immune responses via TLRs and Th2 cytokines.
Authors: Ma P, Bian F, Wang Z, Zheng X, Chotikavanich S, Pflugfelder SC, Li DQ
Invest. Ophthalmol. Vis. Sci., 2009-01-17;50(6):2702-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Chemerin expression marks early psoriatic skin lesions and correlates with plasmacytoid dendritic cell recruitment.
Authors: Albanesi C, Scarponi C, Pallotta S, Daniele R, Bosisio D, Madonna S, Fortugno P, Gonzalvo-Feo S, Franssen JD, Parmentier M, De Pita O, Girolomoni G, Sozzani S
J. Exp. Med., 2008-12-29;206(1):249-58.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Immunologic analysis of HIV-uninfected Taiwanese children with BCG-induced disease.
Authors: Lee WI, Liang FC, Huang JL, Jaing TH, Wang CH, Lin TY, Huang YC, Huang WL, Jou R, Hsieh MY, Chia JH, Wu TL
J. Clin. Immunol., 2008-12-13;29(3):319-29.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Cytokine milieu modulates release of thymic stromal lymphopoietin from human keratinocytes stimulated with double-stranded RNA.
Authors: Kinoshita H, Takai T, Le TA, Kamijo S, Wang XL, Ushio H, Hara M, Kawasaki J, Vu AT, Ogawa T, Gunawan H, Ikeda S, Okumura K, Ogawa H
J. Allergy Clin. Immunol., 2008-12-03;123(1):179-86.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Nitric oxide attenuates vascular endothelial cadherin-mediated vascular integrity in human chronic inflammation.
Authors: Hama S, Takeichi O, Fujisaki K, Tanabe N, Maeno M, Ochiai K
Clin. Exp. Immunol., 2008-12-01;154(3):384-90.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Human bronchial intraepithelial T cells produce interferon-gamma and stimulate epithelial cells.
Authors: Hirosako S, Goto E, Fujii K, Tsumori K, Hirata N, Tsumura S, Kamohara H, Kohrogi H
Clin. Exp. Immunol., 2008-11-26;155(2):266-74.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Escherichia coli type 1 pili trigger late IL-8 production by neutrophil-like differentiated PLB-985 cells through a Src family kinase- and MAPK-dependent mechanism.
Authors: Semiramoth N, Gleizes A, Turbica I, Sandre C, Gorges R, Kansau I, Servin A, Chollet-Martin S
J. Leukoc. Biol., 2008-11-17;85(2):310-21.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Low expression of the IL-23/Th17 pathway in atopic dermatitis compared to psoriasis.
Authors: Guttman-Yassky E, Lowes MA, Fuentes-Duculan J, Zaba LC, Cardinale I, Nograles KE, Khatcherian A, Novitskaya I, Carucci JA, Bergman R, Krueger JG
J. Immunol., 2008-11-15;181(10):7420-7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Cytokine-induced CEACAM1 expression on keratinocytes is characteristic for psoriatic skin and contributes to a prolonged lifespan of neutrophils.
Authors: Rahmoun M, Moles JP, Pedretti N, Mathieu M, Fremaux I, Raison-Peyron N, Lecron JC, Yssel H, Pene J
J. Invest. Dermatol., 2008-10-09;129(3):671-81.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Expression and potential function of the CXC chemokine CXCL16 in pancreatic ductal adenocarcinoma.
Authors: Wente MN, Gaida MM, Mayer C, Michalski CW, Haag N, Giese T, Felix K, Bergmann F, Giese NA, Friess H
Int. J. Oncol., 2008-08-01;33(2):297-308.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

C-reactive protein (CRP) induces chemokine secretion via CD11b/ICAM-1 interaction in human adherent monocytes.
Authors: Montecucco F, Steffens S, Burger F, Pelli G, Monaco C, Mach F
J. Leukoc. Biol., 2008-06-30;84(4):1109-19.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Evidence of a role for B cell-activating factor of the TNF family in the pathogenesis of chronic rhinosinusitis with nasal polyps.
Authors: Kato A, Peters A, Suh L, Carter R, Harris KE, Chandra R, Conley D, Grammer LC, Kern R, Schleimer RP
J. Allergy Clin. Immunol., 2008-04-14;121(6):1385-92, 1392.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Distinct subsets of human invariant NKT cells differentially regulate T helper responses via dendritic cells.
Authors: Liu TY, Uemura Y, Suzuki M, Narita Y, Hirata S, Ohyama H, Ishihara O, Matsushita S
Eur. J. Immunol., 2008-04-01;38(4):1012-23.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Upregulation of human cytomegalovirus by HIV type 1 in human lymphoid tissue ex vivo.
Authors: Biancotto A, Iglehart SJ, Lisco A, Vanpouille C, Grivel JC, Lurain NS, Reichelderfer PS, Margolis LB
AIDS Res. Hum. Retroviruses, 2008-03-01;24(3):453-62.
Applications: ELISA (Standard)

Maturing dendritic cells are an important source of IL-29 and IL-20 that may cooperatively increase the innate immunity of keratinocytes.
Authors: Wolk K, Witte K, Witte E, Proesch S, Schulze-Tanzil G, Nasilowska K, Thilo J, Asadullah K, Sterry W, Volk HD, Sabat R
J. Leukoc. Biol., 2008-02-15;83(5):1181-93.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Expression and regulation of CCR1 by airway smooth muscle cells in asthma.
Authors: Joubert P, Lajoie-Kadoch S, Welman M, Dragon S, Letuvee S, Tolloczko B, Halayko AJ, Gounni AS, Maghni K, Hamid Q
J. Immunol., 2008-01-15;180(2):1268-75.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The role of interleukin-22 in hepatitis C virus infection.
Authors: Dambacher J, Beigel F, Zitzmann K, Heeg MH, Goke B, Diepolder HM, Auernhammer CJ, Brand S
Cytokine, 2008-01-11;41(3):209-16.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Fluorescence single-molecule counting assays for high-sensitivity detection of cytokines and chemokines.
Authors: Qui H, Ferrell EP, Nolan N, Phelps BH, Tabibiazar R, Whitney DH, Naelfski EA
Clin. Chem., 2007-11-01;53(11):2010-2.
Applications: ELISA (Standard)

Association of reactive oxygen and nitrogen intermediate and complement levels with apoptosis of peripheral blood mononuclear cells in lupus patients.
Authors: Oates JC, Farrelly LW, Hofbauer AF, Wang W, Gilkeson GS
Arthritis Rheum., 2007-11-01;56(11):3738-47.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Alpha-4/beta-1 and alpha-L/beta-2 integrins mediate cytokine induced lung leukocyte-epithelial adhesion and injury.
Authors: Parmley LA, Elkins ND, Fini MA, Liu YE, Repine JE, Wright RM
Br. J. Pharmacol., 2007-09-10;152(6):915-29.
Species: Rat
Sample Types: In Vivo
Applications: In Vivo

Growth factor induction of Cripto-1 shedding by glycosylphosphatidylinositol-phospholipase D and enhancement of endothelial cell migration.
Authors: Watanabe K, Bianco C, Strizzi L, Hamada S, Mancino M, Bailly V, Mo W, Wen D, Miatkowski K, Gonzales M, Sanicola M, Seno M, Salomon DS
J. Biol. Chem., 2007-08-24;282(43):31643-55.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Angiotensin II controls occludin function and is required for blood brain barrier maintenance: relevance to multiple sclerosis.
Authors: Wosik K, Cayrol R, Dodelet-Devillers A, Berthelet F, Bernard M, Moumdjian R, Bouthillier A, Reudelhuber TL, Prat A
J. Neurosci., 2007-08-22;27(34):9032-42.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Complement receptor 3 blockade promotes IL-12-Mediated Clearance of Porphyromonas gingivalis and Negates Its Virulence In Vivo.
Authors: Hajishengallis G, Shakhatreh MA, Wang M, Liang S
J. Immunol., 2007-08-15;179(4):2359-67.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

TLR3- and Th2 cytokine-dependent production of thymic stromal lymphopoietin in human airway epithelial cells.
Authors: Kato A, Favoreto S, Avila PC, Schleimer RP
J. Immunol., 2007-07-15;179(2):1080-7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Expression and role of CCR6/CCL20 chemokine axis in pulmonary sarcoidosis.
Authors: Facco M, Baesso I, Miorin M, Bortoli M, Cabrelle A, Boscaro E, Gurrieri C, Trentin L, Zambello R, Calabrese F, Cassatella MA, Semenzato G, Agostini C
J. Leukoc. Biol., 2007-07-05;82(4):946-55.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Epithelial overexpression of interleukin-32alpha in inflammatory bowel disease.
Authors: Shioya M, Nishida A, Yagi Y, Ogawa A, Tsujikawa T, Kim-Mitsuyama S, Takayanagi A, Shimizu N, Fujiyama Y, Andoh A
Clin. Exp. Immunol., 2007-06-22;149(3):480-6.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Regulated shedding of transmembrane chemokines by the disintegrin and metalloproteinase 10 facilitates detachment of adherent leukocytes.
Authors: Hundhausen C, Schulte A, Schulz B, Andrzejewski MG, Schwarz N, von Hundelshausen P, Winter U, Paliga K, Reiss K, Saftig P, Weber C, Ludwig A
J. Immunol., 2007-06-15;178(12):8064-72.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Interleukin 31 mediates MAP kinase and STAT1/3 activation in intestinal epithelial cells and its expression is upregulated in inflammatory bowel disease.
Authors: Dambacher J, Beigel F, Seiderer J, Haller D, Goke B, Auernhammer CJ, Brand S
Gut, 2007-04-20;56(9):1257-65.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis.
Authors: Sa SM, Valdez PA, Wu J
J. Immunol., 2007-02-15;178(4):2229-40.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1.
Authors: Biancotto A, Grivel JC, Iglehart SJ, Vanpouille C, Lisco A, Sieg SF, Debernardo R, Garate K, Rodriguez B, Margolis LB, Lederman MM
Blood, 2007-02-08;109(10):4272-9.
Applications: ELISA (Standard)

Prolactin enhances interferon-gamma-induced production of CXC ligand 9 (CXCL9), CXCL10, and CXCL11 in human keratinocytes.
Authors: Kanda N, Watanabe S
Endocrinology, 2007-01-25;148(5):2317-25.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IFN-gamma alters the response of Borrelia burgdorferi-activated endothelium to favor chronic inflammation.
Authors: Dame TM, Orenzoff BL, Palmer LE, Furie MB
J. Immunol., 2007-01-15;178(2):1172-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Interferon-gamma differentially regulates TGF-beta1 and TGF-beta2 expression in human retinal pigment epithelial cells through JAK-STAT pathway.
Authors: Nagineni CN, Cherukuri KS, Kutty V, Detrick B, Hooks JJ
J. Cell. Physiol., 2007-01-01;210(1):192-200.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

HIV-1 pathogenesis differs in rectosigmoid and tonsillar tissues infected ex vivo with CCR5- and CXCR4-tropic HIV-1.
Authors: Grivel JC, Elliott J, Lisco A, Biancotto A, Condack C, Shattock RJ, McGowan I, Margolis L, Anton P
AIDS, 2007;21(10):1263-72.
Species: N/A
Sample Types: N/A
Applications: ELISA (Standard)

Aberrant regulation of synovial T cell activation by soluble costimulatory molecules in rheumatoid arthritis.
Authors: Wan B, Nie H, Liu A, Feng G, He D, Xu R, Zhang Q, Dong C, Zhang JZ
J. Immunol., 2006-12-15;177(12):8844-50.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Oncostatin M enhances CCL21 expression by microvascular endothelial cells and increases the efficiency of dendritic cell trafficking to lymph nodes.
Authors: Sugaya M, Fang L, Cardones AR, Kakinuma T, Jaber SH, Blauvelt A, Hwang ST
J. Immunol., 2006-12-01;177(11):7665-72.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Interleukin-11 potentiates oligodendrocyte survival and maturation, and myelin formation.
Authors: Zhang Y, Taveggia C, Melendez-Vasquez C, Einheber S, Raine CS, Salzer JL, Brosnan CF, John GR
J. Neurosci., 2006-11-22;26(47):12174-85.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium.
Authors: Johnson LA, Clasper S, Holt AP, Lalor PF, Baban D, Jackson DG
J. Exp. Med., 2006-11-20;203(12):2763-77.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

HIV-1-infected and/or immune activated macrophages regulate astrocyte SDF-1 production through IL-1beta.
Authors: Peng H, Erdmann N, Whitney N, Dou H, Gorantla S, Gendelman HE, Ghorpade A, Zheng J
Glia, 2006-11-01;54(6):619-29.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Development of an in vitro pancreatic tissue model to study regulation of islet neogenesis associated protein expression.
Authors: Petropavlovskaia M, Makhlin J, Sampalis J, Rosenberg L
J. Endocrinol., 2006-10-01;191(1):65-81.
Species: Hamster
Sample Types: Whole Cells
Applications: Bioassay

ICOS cooperates with CD28, IL-2, and IFN-gamma and modulates activation of human naive CD4+ T cells.
Authors: Mesturini R, Nicola S, Chiocchetti A, Bernardone IS, Castelli L, Bensi T, Ferretti M, Comi C, Dong C, Rojo JM, Yagi J, Dianzani U
Eur. J. Immunol., 2006-10-01;36(10):2601-12.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Human intestinal intraepithelial lymphocytes keep TNF alpha levels low by cell uptake and feedback inhibition of transcription.
Authors: Ebert EC, Mehta V
Cell. Immunol., 2006-08-17;241(1):7-13.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Increased expression of Th2-associated chemokines in bullous pemphigoid disease. Role of eosinophils in the production and release of these chemokines.
Authors: Gounni Abdelilah S, Wellemans V, Agouli M, Guenounou M, Hamid Q, Beck LA, Lamkhioued B
Clin. Immunol., 2006-06-16;120(2):220-31.
Applications: ELISA (Standard)

IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis.
Authors: Wolk K, Witte E, Wallace E, Docke WD, Kunz S, Asadullah K, Volk HD, Sterry W, Sabat R
Eur. J. Immunol., 2006-05-01;36(5):1309-23.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The apoptotic-cell receptor CR3, but not alphavbeta5, is a regulator of human dendritic-cell immunostimulatory function.
Authors: Skoberne M, Somersan S, Almodovar W, Truong T, Petrova K, Henson PM, Bhardwaj N
Blood, 2006-04-13;108(3):947-55.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Transforming growth factor beta 1(TGF-beta1) down-regulates TNFalpha-induced RANTES production in rheumatoid synovial fibroblasts through NF-kappaB-mediated transcriptional repression.
Authors: Cho ML, Min SY, Chang SH, Kim KW, Heo SB, Lee SH, Park SH, Cho CS, Kim HY
Immunol. Lett., 2006-03-03;105(2):159-66.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Inhibition of interferon-stimulated JAK-STAT signaling by a tick-borne flavivirus and identification of NS5 as an interferon antagonist.
Authors: Best SM, Morris KL, Shannon JG, Robertson SJ, Mitzel DN, Park GS, Boer E, Wolfinbarger JB, Bloom ME
J. Virol., 2005-10-01;79(20):12828-39.
Species: Primate - Chlorocebus pygerythrus (Vervet Monkey)
Sample Types: Whole Cells
Applications: Bioassay

Modulation of GM-CSF release by enantiomers of beta-agonists in human airway smooth muscle.
Authors: Ameredes BT, Calhoun WJ
J. Allergy Clin. Immunol., 2005-07-01;116(1):65-72.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Regulation of peritoneal and systemic neutrophil-derived tumor necrosis factor-alpha release in patients with severe peritonitis: role of tumor necrosis factor-alpha converting enzyme cleavage.
Authors: Kermarrec N, Selloum S, Plantefeve G, Chosidow D, Paoletti X, Lopez A, Mantz J, Desmonts JM, Gougerot-Pocidalo MA, Chollet-Martin S
Crit. Care Med., 2005-06-01;33(6):1359-64.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Ultraviolet radiation-induced injury, chemokines, and leukocyte recruitment: An amplification cycle triggering cutaneous lupus erythematosus.
Authors: Meller S, Winterberg F, Gilliet M, Muller A, Lauceviciute I, Rieker J, Neumann NJ, Kubitza R, Gombert M, Bunemann E, Wiesner U, Franken-Kunkel P, Kanzler H, Dieu-Nosjean MC, Amara A, Ruzicka T, Lehmann P, Zlotnik A, Homey B
Arthritis Rheum., 2005-05-01;52(5):1504-16.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CYP7B expression and activity in fibroblast-like synoviocytes from patients with rheumatoid arthritis: regulation by proinflammatory cytokines.
Authors: Dulos J, van der Vleuten MA, Kavelaars A, Heijnen CJ, Boots AM
Arthritis Rheum., 2005-03-01;52(3):770-8.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Expression of toll-like receptors 2 and 4 in rheumatoid synovial tissue and regulation by proinflammatory cytokines interleukin-12 and interleukin-18 via interferon-gamma.
Authors: Radstake TR, Roelofs MF, Jenniskens YM, van Riel PL, Barrera P
Arthritis Rheum., 2004-12-01;50(12):3856-65.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis.
Authors: Gibot S, Kolopp-Sarda MN, Bollaert PE, Lozniewski A, Mory F, Levy B, Faure GC
J. Exp. Med., 2004-11-22;200(11):1419-26.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CC chemokine ligand 18, an atopic dermatitis-associated and dendritic cell-derived chemokine, is regulated by staphylococcal products and allergen exposure.
Authors: Pivarcsi A, Gombert M, Dieu-Nosjean MC, Kubitza R, Meller S, Rieker J, Muller A, Da Cunha L, Haahtela A, Sonkoly E, Fridman WH, Alenius H, Kemeny L, Ruzicka T, Zlotnik A
J. Immunol., 2004-11-01;173(9):5810-7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Proinflammatory mediators elicit secretion of the intracellular B-lymphocyte stimulator pool (BLyS) that is stored in activated neutrophils: implications for inflammatory diseases.
Authors: Scapini P, Carletto A, Nardelli B, Calzetti F, Roschke V, Merigo F, Tamassia N, Pieropan S, Biasi D, Sbarbati A, Sozzani S, Bambara L, Cassatella MA
Blood, 2004-09-09;105(2):830-7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways.
Authors: Kao CY, Chen Y, Thai P, Wachi S, Huang F, Kim C, Harper RW, Wu R
J. Immunol., 2004-09-01;173(5):3482-91.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IL-22 increases the innate immunity of tissues.
Authors: Wolk K, Kunz S, Witte E, Friedrich M, Asadullah K, Sabat R
Immunity, 2004-08-01;21(2):241-54.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Induction of lysosomal and plasma membrane-bound sialidases in human T-cells via T-cell receptor.
Authors: Wang P, Zhang J, Bian H, Wu P, Kuvelkar R, Kung TT, Crawley Y, Egan RW, Billah MM
Biochem. J., 2004-06-01;380(0):425-33.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Rapid chemokine secretion from endothelial cells originates from 2 distinct compartments.
Authors: Oynebraten I, Bakke O, Brandtzaeg P, Johansen FE, Haraldsen G
Blood, 2004-03-25;104(2):314-20.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

TNF-related apoptosis-inducing ligand mediates human neuronal apoptosis: links to HIV-1-associated dementia.
Authors: Ryan LA, Peng H, Erichsen DA, Huang Y, Persidsky Y, Zhou Y, Gendelman HE, Zheng J
J. Neuroimmunol., 2004-03-01;148(1):127-39.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Interferon-gamma inhibits transforming growth factor-beta production in human airway epithelial cells by targeting Smads.
Authors: Wen FQ, Liu X, Kobayashi T, Abe S, Fang Q, Kohyama T, Ertl R, Terasaki Y, Manouilova L, Rennard SI
Am. J. Respir. Cell Mol. Biol., 2004-01-12;30(6):816-22.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Direct comparison of traditional ELISAs and membrane protein arrays for detection and quantification of human cytokines.
Authors: Copeland S, Siddiqui J, Remick D
J. Immunol. Methods, 2004-01-01;284(1):99-106.
Applications: ELISA (Standard)

High-affinity autoantibodies specifically eliminate granulocyte-macrophage colony-stimulating factor activity in the lungs of patients with idiopathic pulmonary alveolar proteinosis.
Authors: Uchida K, Nakata K, Trapnell BC, Terakawa T, Hamano E, Mikami A, Matsushita I, Seymour JF, Oh-Eda M, Ishige I, Eishi Y, Kitamura T, Yamada Y, Hanaoka K, Keicho N
Blood, 2003-09-25;103(3):1089-98.
Species: Human
Sample Types:
Applications: Binding Assay

Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation.
Authors: McLoughlin RM, Witowski J, Robson RL, Wilkinson TS, Hurst SM, Williams AS, Williams JD, Rose-John S, Jones SA, Topley N
J. Clin. Invest., 2003-08-01;112(4):598-607.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

In human B cells, IL-12 triggers a cascade of molecular events similar to Th1 commitment.
Authors: Durali D, de Goer de Herve MG, Giron-Michel J, Azzarone B, Delfraissy JF, Taoufik Y
Blood, 2003-07-31;102(12):4084-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The human anti-CD30 antibody 5F11 shows in vitro and in vivo activity against malignant lymphoma.
Authors: Borchmann P, Treml JF, Hansen H, Gottstein C, Schnell R, Staak O, Zhang HF, Davis T, Keler T, Diehl V, Graziano RF, Engert A
Blood, 2003-07-24;102(10):3737-42.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis.
Authors: Groh V, Bruhl A, El-Gabalawy H, Nelson JL, Spies T
Proc. Natl. Acad. Sci. U.S.A., 2003-07-23;100(16):9452-7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

HIV-1 protein Vpr suppresses IL-12 production from human monocytes by enhancing glucocorticoid action: potential implications of Vpr coactivator activity for the innate and cellular immunity deficits observed in HIV-1 infection.
Authors: Mirani M, Elenkov I, Volpi S, Hiroi N, Chrousos GP, Kino T
J. Immunol., 2002-12-01;169(11):6361-8.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Expression of CTLA-4 by human monocytes.
Authors: Wang XB, Giscombe R, Yan Z
Scand. J. Immunol., 2002-01-01;55(1):53-60.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Expression of Fas/CD95 and Bcl-2 by primitive hematopoietic progenitors freshly isolated from human fetal liver.
Authors: Barcena A, Park SW, Banapour B, Muench MO, Mechetner E
Blood, 1996-09-15;88(6):2013-25.
Species: Human
Sample Types:
Applications: Bioassay