Recombinant Human IgG1 Fc Protein, CF

Analyzed by SEC-MALS
Catalog # Availability Size / Price Qty
110-HG-100
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Recombinant Human IgG1 Fc Protein SEC-MALS.
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Product Details
Citations (123)
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Recombinant Human IgG1 Fc Protein, CF Summary

Product Specifications

Purity
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
Activity
Bioassay data are not available.
Source
Mouse myeloma cell line, NS0-derived human IgG1 protein
IEGRMD Human IgG1
(Pro100-Lys330)
Substitutions: Leu117Ala, Leu118Glu, Gly120Ala, Thr276Ala
Accession # P01857.1
N-terminus C-terminus
Accession #
N-terminal Sequence
Analysis
Ile
Structure / Form
Dimer
Predicted Molecular Mass
26.6 kDa
SDS-PAGE
30-35 kDa, reducing conditions

Product Datasheets

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110-HG

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

110-HG

Formulation Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution

It is recommended that sterile PBS containing at least 0.1% human serum albumin or bovine serum albumin be added to the vial to prepare a stock solution of no less than 100 μg/mL.

Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Scientific Data

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Recombinant Human IgG1/Fc Protein (Catalog # 110-HG) has a molecular weight (MW) of 55.8 kDa as analyzed by SEC-MALS, suggesting that this protein is a dimer. MW may differ from predicted MW due to post-translational modifications (PTMs) present (i.e. Glycosylation).

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: IgG1

R&D Systems offers a range of secondary antibodies and controls for flow cytometry, immunohistochemistry, and Western blotting. We provide species-specific secondary antibodies that are available with a variety of conjugated labels.

Our NorthernLights fluorescent secondary antibodies are bright and resistant to photobleaching. We are currently offering secondary antibodies recognizing mouse, rat, goat, sheep, and rabbit IgG as well as chicken IgY. These reagents are available with three distinct excitation and emission maxima, making them ideal for multi-color fluorescence microscopy.

Long Name
Immunoglobulin G1
Alternate Names
IgG1; Igh-4; RGD1359539; VH7183

Citations for Recombinant Human IgG1 Fc Protein, CF

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

123 Citations: Showing 1 - 10
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  1. Eph-ephrin signaling couples endothelial cell sorting and arterial specification
    Authors: Stewen, J;Kruse, K;Godoi-Filip, AT;Zenia, ;Jeong, HW;Adams, S;Berkenfeld, F;Stehling, M;Red-Horse, K;Adams, RH;Pitulescu, ME;
    Nature communications
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  2. Boosting BDNF in muscle rescues impaired axonal transport in a mouse model of DI-CMTC peripheral neuropathy
    Authors: Rhymes, ER;Simkin, RL;Qu, J;Villarroel-Campos, D;Surana, S;Tong, Y;Shapiro, R;Burgess, RW;Yang, XL;Schiavo, G;Sleigh, JN;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Transfected Whole Cells
    Applications: Immunoprecipitation
  3. Tumor cell-intrinsic PD-1 promotes Merkel cell carcinoma growth by activating downstream mTOR-mitochondrial ROS signaling
    Authors: Martins, C;Rasbach, E;Heppt, MV;Singh, P;Kulcsar, Z;Holzgruber, J;Chakraborty, A;Mucciarone, K;Kleffel, S;Brandenburg, A;Hoetzenecker, W;Rahbari, NN;DeCaprio, JA;Thakuria, M;Murphy, GF;Ramsey, MR;Posch, C;Barthel, SR;Schatton, T;
    Science advances
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  4. NBL1 Reduces Corneal Fibrosis and Scar Formation after Wounding
    Authors: Tsai, CH;Liu, E;Phan, A;Lu, KL;Mei, H;
    Biomolecules
    Species: Human, Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  5. Clinical Staphylococcus aureus inhibits human T-cell activity through interaction with the PD-1 receptor
    Authors: Mellergaard, M;Skovbakke, SL;Jepsen, SD;Panagiotopoulou, N;Hansen, ABR;Tian, W;Lund, A;Høgh, RI;Møller, SH;Guérillot, R;Hayes, AS;Erikstrup, LT;Andresen, L;Peleg, AY;Larsen, AR;Stinear, TP;Handberg, A;Erikstrup, C;Howden, BP;Goletz, S;Frees, D;Skov, S;
    mBio
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry Control
  6. The Cell-Autonomous Pro-Metastatic Activities of PD-L1 in Breast Cancer Are Regulated by N-Linked Glycosylation-Dependent Activation of STAT3 and STAT1
    Authors: Erlichman, N;Meshel, T;Baram, T;Abu Raiya, A;Horvitz, T;Ben-Yaakov, H;Ben-Baruch, A;
    Cells
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  7. Structural insights into Siglec-15 reveal glycosylation dependency for its interaction with T cells through integrin CD11b
    Authors: Lenza, MP;Egia-Mendikute, L;Antoñana-Vildosola, A;Soares, CO;Coelho, H;Corzana, F;Bosch, A;Manisha, P;Quintana, JI;Oyenarte, I;Unione, L;Moure, MJ;Azkargorta, M;Atxabal, U;Sobczak, K;Elortza, F;Sutherland, JD;Barrio, R;Marcelo, F;Jiménez-Barbero, J;Palazon, A;Ereño-Orbea, J;
    Nature communications
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  8. Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Influence on Soluble and Membrane Bound ICOS in Combination with Immune Checkpoint Blockade
    Authors: Li, X;Li, J;Zheng, Y;Lee, SJ;Zhou, J;Giobbie-Hurder, A;Butterfield, LH;Dranoff, G;Hodi, FS;
    Cancer immunology research
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization Control
  9. Semaphorin 4D induced inhibitory synaptogenesis decreases epileptiform activity and alters progression to Status Epilepticus in mice
    Authors: Adel, SS;Clarke, VRJ;Evans-Strong, A;Maguire, J;Paradis, S;
    Epilepsy research
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  10. AXL-Receptor Targeted 14FN3 Based Single Domain Proteins (Pronectins�) from 3 Synthetic Human Libraries as Components for Exploring Novel Bispecific Constructs against Solid Tumors
    Authors: CA Hokanson, E Zacco, G Cappuccill, T Odineca, R Crea
    Biomedicines, 2022-12-08;10(12):.
    Species: Mouse
    Sample Types: Whole Cell
    Applications: Bioassay
  11. Identification of TFPI as a receptor reveals recombination-driven receptor switching in Clostridioides difficile toxin B variants
    Authors: S Tian, X Xiong, J Zeng, S Wang, BJ Tremblay, P Chen, B Chen, M Liu, P Chen, K Sheng, D Zeve, W Qi, DT Breault, C Rodríguez, R Gerhard, R Jin, AC Doxey, M Dong
    Nature Communications, 2022-11-09;13(1):6786.
    Species: Human
    Sample Types: Protein
    Applications: Reference Standard
  12. Altered Circulating Follicular T Helper Cell Subsets and Follicular T Regulatory Cells Are Indicators of a Derailed B Cell Response in Lupus, Which Could Be Modified by Targeting IL-21R
    Authors: K Szabó, I Jámbor, K Pázmándi, N Nagy, G Papp, T Tarr
    International Journal of Molecular Sciences, 2022-10-13;23(20):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  13. NKp44-based chimeric antigen receptor effectively redirects primary T cells against synovial sarcoma
    Authors: Y Murayama, Y Kasahara, N Kubo, C Shin, M Imamura, N Oike, T Ariizumi, A Saitoh, M Baba, T Miyazaki, Y Suzuki, Y Ling, S Okuda, K Mihara, A Ogose, H Kawashima, C Imai
    Translational Oncology, 2022-08-20;25(0):101521.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  14. Distinct antibody clones detect PD-1 checkpoint expression and block PD-L1 interactions on live murine melanoma cells
    Authors: C Martins, M Silva, E Rasbach, P Singh, Y Itoh, JB Williams, E Statham, A Meurer, DV Martinez, A Brandenbur, MV Heppt, SR Barthel, T Schatton
    Scientific Reports, 2022-07-21;12(1):12491.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  15. Neuropilin 1 and its inhibitory ligand mini-tryptophanyl-tRNA synthetase inversely regulate VE-cadherin turnover and vascular permeability
    Authors: N Gioelli, LJ Neilson, N Wei, G Villari, W Chen, B Kuhle, M Ehling, F Maione, S Willox, S Brundu, D Avanzato, G Koulouras, M Mazzone, E Giraudo, XL Yang, D Valdembri, S Zanivan, G Serini
    Nature Communications, 2022-07-20;13(1):4188.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: Bioassay
  16. EPH receptor tyrosine kinases phosphorylate the PAR-3 scaffold protein to modulate downstream signaling networks
    Authors: SL Banerjee, F Lessard, FJM Chartier, K Jacquet, AI Osornio-He, V Teyssier, K Ghani, N Lavoie, JN Lavoie, M Caruso, P Laprise, S Elowe, JP Lambert, N Bisson
    Cell Reports, 2022-07-05;40(1):111031.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  17. 3D Visualization of Human Blood Vascular Networks Using Single-Domain Antibodies Directed against Endothelial Cell-Selective Adhesion Molecule (ESAM)
    Authors: NR Hansmeier, IS Büschlen, RY Behncke, S Ulferts, R Bisoendial, R Hägerling
    International Journal of Molecular Sciences, 2022-04-15;23(8):.
    Species: N/A
    Sample Types: Whole Cells
    Applications: Bioassay
  18. Ephrin receptor A10 monoclonal antibodies and the derived chimeric antigen receptor T cells exert an antitumor response in mouse models of triple-negative breast cancer
    Authors: JH Cha, LC Chan, YN Wang, YY Chu, CH Wang, HH Lee, W Xia, WC Shyu, SP Liu, J Yao, CW Chang, FR Cheng, J Liu, SO Lim, JL Hsu, WH Yang, GN Hortobagyi, C Lin, L Yang, D Yu, LB Jeng, MC Hung
    The Journal of Biological Chemistry, 2022-03-10;0(0):101817.
    Species: N/A
    Sample Types: Protein
    Applications: ELISA Capture
  19. RTN4/Nogo-A-S1PR2 negatively regulates angiogenesis and secondary neural repair through enhancing vascular autophagy in the thalamus after cerebral cortical infarction
    Authors: P Xiao, J Gu, W Xu, X Niu, J Zhang, J Li, Y Chen, Z Pei, J Zeng, S Xing
    Autophagy, 2022-03-09;0(0):1-20.
    Species: Rat
    Sample Types: In Vivo
    Applications: In Vivo
  20. Tumor Cell-Autonomous Pro-Metastatic Activities of PD-L1 in Human Breast Cancer Are Mediated by PD-L1-S283 and Chemokine Axes
    Authors: N Erlichman, T Baram, T Meshel, D Morein, B Da'adoosh, A Ben-Baruch
    Cancers, 2022-02-18;14(4):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  21. Targeting necroptosis in muscle fibers ameliorates inflammatory myopathies
    Authors: M Kamiya, F Mizoguchi, K Kawahata, D Wang, M Nishibori, J Day, C Louis, IP Wicks, H Kohsaka, S Yasuda
    Nature Communications, 2022-01-10;13(1):166.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  22. Receptor Activator of NF-kappaB (RANK) Confers Resistance to Chemotherapy in AML and Associates with Dismal Disease Course
    Authors: KL Clar, LM Weber, BJ Schmied, JS Heitmann, M Marconato, C Tandler, P Schneider, HR Salih
    Cancers, 2021-12-04;13(23):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  23. S1P Increases VEGF Production in Osteoblasts and Facilitates Endothelial Progenitor Cell Angiogenesis by Inhibiting miR-16-5p Expression via the c-Src/FAK Signaling Pathway in Rheumatoid Arthritis
    Authors: CC Huang, TT Tseng, SC Liu, YY Lin, YY Law, SL Hu, SW Wang, CH Tsai, CH Tang
    Cells, 2021-08-23;10(8):.
    Species: Human
    Sample Types: Reference Standard
  24. A subthreshold synaptic mechanism regulating BDNF expression and resting synaptic strength
    Authors: PM Horvath, NL Chanaday, B Alten, ET Kavalali, LM Monteggia
    Cell Reports, 2021-08-03;36(5):109467.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Reference Standard
  25. Computational design of a synthetic PD-1 agonist
    Authors: CM Bryan, GJ Rocklin, MJ Bick, A Ford, S Majri-Morr, AV Kroll, CJ Miller, L Carter, I Goreshnik, A Kang, F DiMaio, KV Tarbell, D Baker
    Proceedings of the National Academy of Sciences of the United States of America, 2021-07-20;118(29):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  26. Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a child
    Authors: M Ogishi, R Yang, C Aytekin, D Langlais, M Bourgey, T Khan, FA Ali, M Rahman, OM Delmonte, M Chrabieh, P Zhang, C Gruber, SJ Pelham, AN Spaan, J Rosain, WT Lei, S Drutman, MD Hellmann, MK Callahan, M Adamow, P Wong, JD Wolchok, G Rao, CS Ma, Y Nakajima, T Yaguchi, K Chamoto, SC Williams, JF Emile, F Rozenberg, MS Glickman, F Rapaport, G Kerner, G Allington, I Tezcan, D Cagdas, FO Hosnut, F Dogu, A Ikinciogul, VK Rao, L Kainulaine, V Béziat, J Bustamante, S Vilarinho, RP Lifton, B Boisson, L Abel, D Bogunovic, N Marr, LD Notarangel, SG Tangye, T Honjo, P Gros, S Boisson-Du, JL Casanova
    Nature Medicine, 2021-06-28;0(0):.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: Bioassay
  27. Novel human neutralizing mAbs specific for Spike-RBD of SARS-CoV-2
    Authors: M Passariell, C Gentile, V Ferrucci, E Sasso, C Vetrei, G Fusco, M Viscardi, S Brandi, P Cerino, N Zambrano, M Zollo, C De Lorenzo
    Scientific Reports, 2021-05-26;11(1):11046.
    Species: Human
    Sample Types: Virus
    Applications: Affinity Purification
  28. CD200-CD200R immune checkpoint engagement regulates ILC2 effector function and ameliorates lung inflammation in asthma
    Authors: P Shafiei-Ja, DG Helou, BP Hurrell, E Howard, C Quach, JD Painter, L Galle-Treg, M Li, YE Loh, O Akbari
    Nature Communications, 2021-05-05;12(1):2526.
    Species: Human, Mouse
    Sample Types: In Vivo, Whole Cells
    Applications: Bioassay, In Vivo
  29. Aggressive and recurrent ovarian cancers upregulate ephrinA5, a non-canonical effector of EphA2 signaling duality
    Authors: J Jukonen, L Moyano-Gal, K Höpfner, EA Pietilä, L Lehtinen, K Huhtinen, E Gucciardo, J Hynninen, S Hietanen, S Grénman, PM Ojala, O Carpén, K Lehti
    Scientific Reports, 2021-04-23;11(1):8856.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  30. Pharmaceutical immunoglobulin G impairs anti-carcinoma activity of oxaliplatin in colon cancer cells
    Authors: Y Shang, X Zhang, L Lu, K Jiang, M Krohn, S Matschos, CS Mullins, B Vollmar, D Zechner, P Gong, M Linnebache
    British Journal of Cancer, 2021-02-09;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  31. SHP-1 Regulates Antigen Cross-Presentation and Is Exploited by Leishmania to Evade Immunity
    Authors: S C Khouili, ECL Cook, E Hernández-, M Martínez-L, R Conde-Garr, S Iborra
    Cell Rep, 2020-12-01;33(9):108468.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  32. ROBO2 signaling in lung development regulates SOX2/SOX9 balance, branching morphogenesis and is dysregulated in nitrofen-induced congenital diaphragmatic hernia
    Authors: AN Gonçalves, J Correia-Pi, C Nogueira-S
    Respir Res, 2020-11-18;21(1):302.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Cell Culture
  33. The Oncoprotein SKI Acts as A Suppressor of NK Cell-Mediated Immunosurveillance in PDAC
    Authors: V Ponath, M Frech, M Bittermann, R Al Khayer, A Neubauer, C Brendel, E Pogge von
    Cancers (Basel), 2020-10-03;12(10):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  34. Glycosaminoglycans bind human IL-27 and regulate its activity
    Authors: MC Cavé, S Maillard, K Hildenbran, C Mamelonet, MJ Feige, O Devergne
    Eur. J. Immunol., 2020-07-02;0(0):.
    Species: Human
    Sample Types: Protein
    Applications: Bioassay
  35. Inhibition of Tumor VEGFR2 Induces Serine 897 EphA2-Dependent Tumor Cell Invasion and Metastasis in NSCLC
    Authors: C Volz, S Breid, C Selenz, A Zaplatina, K Golfmann, L Meder, F Dietlein, S Borchmann, S Chatterjee, M Siobal, J Schöttle, A Florin, M Koker, M Nill, L Ozreti?, N Uhlenbrock, S Smith, R Büttner, H Miao, B Wang, HC Reinhardt, D Rauh, M Hallek, A Acker-Palm, LC Heukamp, RT Ullrich
    Cell Rep, 2020-04-28;31(4):107568.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  36. Characterization of BAY 1905254, an Immune Checkpoint Inhibitor Targeting the Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2)
    Authors: J Huetter, U Gritzan, I Gutcher, WD Doecke, MV Luetke-Eve, S Golfier, HG Roider, AL Frisk, J Hunter, A Pow, A Drake, Z Levine, O Levy, M Azulay, I Barbiro, G Cojocaru, I Vaknin, B Kreft, L Roese
    Cancer Immunol Res, 2020-04-20;8(7):895-911.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  37. The secreted protein DEL-1 activates a beta3 integrin-FAK-ERK1/2-RUNX2 pathway and promotes osteogenic differentiation and bone regeneration
    Authors: DY Yuh, T Maekawa, X Li, T Kajikawa, K Bdeir, T Chavakis, G Hajishenga
    J. Biol. Chem., 2020-04-12;295(21):7261-7273.
    Species: Mouse, Transgenic Mouse
    Sample Types: In Vivo, Whole Cells
    Applications: Bioassay, In Vivo
  38. CD300lf is the primary physiologic receptor of murine norovirus but not human norovirus
    Authors: VR Graziano, FC Walker, EA Kennedy, J Wei, K Ettayebi, MS Strine, RB Filler, E Hassan, LL Hsieh, AS Kim, AO Kolawole, CE Wobus, LC Lindesmith, RS Baric, MK Estes, RC Orchard, MT Baldridge, CB Wilen
    PLoS Pathog., 2020-04-06;16(4):e1008242.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  39. Endothelial EphB4 maintains vascular integrity and transport function in adult heart
    Authors: G Luxán, J Stewen, N Díaz, K Kato, SK Maney, A Aravamudha, F Berkenfeld, N Nagelmann, HC Drexler, D Zeuschner, C Faber, H Schillers, S Hermann, J Wiseman, JM Vaquerizas, ME Pitulescu, RH Adams
    Elife, 2019-11-29;8(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  40. Increased expression of fibronectin leucine-rich transmembrane protein 3 in the dorsal root ganglion induces neuropathic pain in rats
    Authors: M Yamada, Y Fujita, Y Hayano, H Hayakawa, K Baba, H Mochizuki, T Yamashita
    J. Neurosci., 2019-07-25;0(0):.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: ELISA Capture
  41. CD200R deletion promotes a neutrophil niche for Francisella tularensis and increases infectious burden and mortality
    Authors: J Casulli, ME Fife, SA Houston, S Rossi, J Dow, ED Williamson, GC Clark, T Hussell, RV D'Elia, MA Travis
    Nat Commun, 2019-05-09;10(1):2121.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  42. Live nanoscopic to mesoscopic topography reconstruction with an optical microscope for chemical and biological samples
    Authors: O Theodoly, N Garcia-Sey, F Bedu, X Luo, S Gabriele, T Mignot, J Giermanska, JP Chapel, M Métivier, MP Valignat
    PLoS ONE, 2018-12-12;13(12):e0207881.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  43. TBC1d24-ephrinB2 interaction regulates contact inhibition of locomotion in neural crest cell migration
    Authors: J Yoon, YS Hwang, M Lee, J Sun, HJ Cho, L Knapik, IO Daar
    Nat Commun, 2018-08-28;9(1):3491.
    Species: Xenopus
    Sample Types: Whole Cells
    Applications: Bioassay
  44. Combined blockade of IL-6 and PD-1/PD-L1 signaling abrogates mutual regulation of their immunosuppressive effects in the tumor microenvironment
    Authors: H Tsukamoto, K Fujieda, A Miyashita, S Fukushima, T Ikeda, Y Kubo, S Senju, H Ihn, Y Nishimura, H Oshiumi
    Cancer Res., 2018-07-02;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  45. NCAM2 Fibronectin type-III domains form a rigid structure that binds and activates the Fibroblast Growth Factor Receptor
    Authors: KK Rasmussen, MH Falkesgaar, M Winther, NK Roed, CL Quistgaard, MN Teisen, SM Edslev, DL Petersen, A Aljubouri, C Christense, PW Thulstrup, L Lo Leggio, K Teilum, PS Walmod
    Sci Rep, 2018-06-12;8(1):8957.
    Applications: Bioassay
  46. Antibody dependent cellular phagocytosis by macrophages is a novel mechanism of action of elotuzumab
    Authors: AT Kurdi, SV Glavey, NA Bezman, A Jhatakia, JL Guerriero, S Manier, M Moschetta, Y Mishima, A Roccaro, A Detappe, CJ Liu, A Sacco, D Huynh, YT Tai, MD Robbins, J Azzi, IM Ghobrial
    Mol. Cancer Ther., 2018-04-13;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  47. TREM2 Is a Receptor for ?-Amyloid that Mediates Microglial Function
    Authors: Y Zhao, X Wu, X Li, LL Jiang, X Gui, Y Liu, Y Sun, B Zhu, JC Piña-Cresp, M Zhang, N Zhang, X Chen, G Bu, Z An, TY Huang, H Xu
    Neuron, 2018-03-07;97(5):1023-1031.e7.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: Bioassay, Immunoprecipitation
  48. The product of the ?-secretase processing of ephrinB2 regulates VE-cadherin complexes and angiogenesis
    Authors: NA Warren, G Voloudakis, Y Yoon, NK Robakis, A Georgakopo
    Cell. Mol. Life Sci., 2018-02-10;0(0):.
    Species: Bovine
    Sample Types: Whole Cells
    Applications: Bioassay
  49. EphrinA1-Fc attenuates myocardial ischemia/reperfusion injury in mice
    Authors: A DuSablon, J Parks, K Whitehurst, H Estes, R Chase, E Vlahos, U Sharma, D Wert, J Virag
    PLoS ONE, 2017-12-13;12(12):e0189307.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  50. Secreted protein Del-1 regulates myelopoiesis in the hematopoietic stem cell niche
    Authors: I Mitroulis, LS Chen, RP Singh, I Kourtzelis, M Economopou, T Kajikawa, M Troullinak, A Ziogas, K Ruppova, K Hosur, T Maekawa, B Wang, P Subramania, T Tonn, P Verginis, M von Bonin, M Wobus, M Bornhäuser, T Grinenko, M Di Scala, A Hidalgo, B Wielockx, G Hajishenga, T Chavakis
    J. Clin. Invest., 2017-08-28;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  51. Expression, refolding and spectroscopic characterization of fibronectin type III (FnIII)-homology domains derived from human fibronectin leucine rich transmembrane protein (FLRT)-1, -2, and -3
    Authors: L Yang, M Hansen Fal, PW Thulstrup, PS Walmod, L Lo Leggio, K Krighaar R
    PeerJ, 2017-07-07;5(0):e3550.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: Bioassay
  52. Interleukin-10-producing LAG3(+) regulatory T cells are associated with disease activity and abatacept treatment in rheumatoid arthritis
    Authors: S Nakachi, S Sumitomo, Y Tsuchida, H Tsuchiya, M Kono, R Kato, K Sakurai, N Hanata, Y Nagafuchi, S Tateishi, H Kanda, T Okamura, K Yamamoto, K Fujio
    Arthritis Res. Ther., 2017-05-16;19(1):97.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  53. Dynamic Arc SUMOylation and Selective Interaction with F-Actin-Binding Protein Drebrin A in LTP Consolidation In Vivo
    Authors: RR Nair, S Patil, A Tiron, T Kanhema, D Panja, L Schiro, K Parobczak, G Wilczynski, CR Bramham
    Front Synaptic Neurosci, 2017-05-10;9(0):8.
    Species: Rat
    Sample Types: In Vivo
    Applications: In Vivo
  54. Semaphorin 3A Increases FAK Phosphorylation at Focal Adhesions to Modulate MDA-MB-231 Cell Migration and Spreading on Different Substratum Concentrations
    Authors: S Gehler, FV Compere, AM Miller
    Int J Breast Cancer, 2017-01-15;2017(0):9619734.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  55. ICAM-5/Telencephalin Is a Functional Entry Receptor for Enterovirus D68
    Authors: Wei Wei
    Cell Host Microbe, 2016-10-27;20(5):631-641.
    Applications: Bioassay
  56. Tissue factor is induced by interleukin-33 in human endothelial cells: a new link between coagulation and inflammation
    Sci Rep, 2016-05-04;6(0):25171.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  57. Semaphorin 7A Aggravates Pulmonary Inflammation during Lung Injury.
    Authors: Roth J, Kohler D, Schneider M, Granja T, Rosenberger P
    PLoS ONE, 2016-01-11;11(1):e0146930.
    Species: Human
    Sample Types: Whole Cells
    Applications: Control
  58. Interleukin-21 Induces Proliferation and Proinflammatory Cytokine Profile of Fibroblast-like Synoviocytes of Patients with Rheumatoid Arthritis.
    Authors: Xing R, Yang L, Jin Y, Sun L, Li C, Li Z, Zhao J, Liu X
    Scand J Immunol, 2016-01-01;83(1):64-71.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  59. Mutant B-Raf(V600E) Promotes Melanoma Paracellular Transmigration by Inducing Thrombin-mediated Endothelial Junction Breakdown.
    Authors: Zhang P, Feng S, Liu G, Wang H, Zhu H, Ren Q, Bai H, Fu C, Dong C
    J Biol Chem, 2015-10-26;291(5):2087-106.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  60. Aspirin-Exacerbated Respiratory Disease Involves a Cysteinyl Leukotriene-Driven IL-33-Mediated Mast Cell Activation Pathway.
    Authors: Liu T, Kanaoka Y, Barrett N, Feng C, Garofalo D, Lai J, Buchheit K, Bhattacharya N, Laidlaw T, Katz H, Boyce J
    J Immunol, 2015-09-04;195(8):3537-45.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  61. NKP30-B7-H6 Interaction Aggravates Hepatocyte Damage through Up-Regulation of Interleukin-32 Expression in Hepatitis B Virus-Related Acute-On-Chronic Liver Failure.
    Authors: Zou Y, Bao J, Pan X, Lu Y, Liao S, Wang X, Wang G, Lin D
    PLoS ONE, 2015-08-04;10(8):e0134568.
    Species: Human
    Sample Types: Whole Cells
    Applications: Control
  62. Receptor tyrosine kinase Axl is required for resistance of leukemic cells to FLT3-targeted therapy in acute myeloid leukemia.
    Authors: Park I, Mundy-Bosse B, Whitman S, Zhang X, Warner S, Bearss D, Blum W, Marcucci G, Caligiuri M
    Leukemia, 2015-06-19;29(12):2382-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  63. The paradox of high availability and low recognition of soluble HLA-G by LILRB1 receptor in rheumatoid arthritis patients.
    Authors: Veit T, Chies J, Switala M, Wagner B, Horn P, Busatto M, Brenol C, Tavares Brenol J, Machado Xavier R, Rebmann V
    PLoS ONE, 2015-04-08;10(4):e0123838.
    Species: Human
    Sample Types: Protein
    Applications: Bioassay
  64. EphrinB2 controls vessel pruning through STAT1-JNK3 signalling.
    Authors: Salvucci O, Ohnuki H, Maric D, Hou X, Li X, Yoon S, Segarra M, Eberhart C, Acker-Palmer A, Tosato G
    Nat Commun, 2015-03-26;6(0):6576.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  65. IL-24 inhibits lung cancer cell migration and invasion by disrupting the SDF-1/CXCR4 signaling axis.
    Authors: Panneerselvam J, Jin J, Shanker M, Lauderdale J, Bates J, Wang Q, Zhao Y, Archibald S, Hubin T, Ramesh R
    PLoS ONE, 2015-03-16;10(3):e0122439.
    Species: Human
    Sample Types: Whole Cells
  66. Epithelial and stromal cell urokinase plasminogen activator receptor expression differentially correlates with survival in rectal cancer stages B and C patients.
    Authors: Ahn, Seong Be, Chan, Charles, Dent, Owen F, Mohamedali, Abidali, Kwun, Sun Youn, Clarke, Candice, Fletcher, Julie, Chapuis, Pierre H, Nice, Edouard, Baker, Mark S
    PLoS ONE, 2015-02-18;10(2):e0117786.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  67. ChemR23, the receptor for chemerin and resolvin E1, is expressed and functional on M1 but not on M2 macrophages.
    Authors: Herova M, Schmid M, Gemperle C, Hersberger M
    J Immunol, 2015-01-30;194(5):2330-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Isotype Control
  68. Different patterns of electrical activity lead to long-term potentiation by activating different intracellular pathways.
    Authors: Zhu G, Liu Y, Wang Y, Bi X, Baudry M
    J Neurosci, 2015-01-14;35(2):621-33.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Control
  69. Chemokine-coupled beta2 integrin-induced macrophage Rac2-Myosin IIA interaction regulates VEGF-A mRNA stability and arteriogenesis.
    Authors: Morrison A, Yarovinsky T, Young B, Moraes F, Ross T, Ceneri N, Zhang J, Zhuang Z, Sinusas A, Pardi R, Schwartz M, Simons M, Bender J
    J Exp Med, 2014-09-01;211(10):1957-68.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  70. Development of the prethalamus is crucial for thalamocortical projection formation and is regulated by Olig2.
    Authors: Ono, Katsuhik, Clavairoly, Adrien, Nomura, Tadashi, Gotoh, Hitoshi, Uno, Aoi, Armant, Olivier, Takebayashi, Hirohide, Zhang, Qi, Shimamura, Kenji, Itohara, Shigeyos, Parras, Carlos M, Ikenaka, Kazuhiro
    Development, 2014-05-01;141(10):2075-84.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Control
  71. A polysaccharide virulence factor of a human fungal pathogen induces neutrophil apoptosis via NK cells.
    Authors: Robinet P, Baychelier F, Fontaine T, Picard C, Debre P, Vieillard V, Latge J, Elbim C
    J Immunol, 2014-04-30;192(11):5332-42.
    Species: Human
    Sample Types: Whole Blood
    Applications: Isotype Control
  72. Dynorphin up-regulation in the dentate granule cell mossy fiber pathway following chronic inhibition of GluN2B-containing NMDAR is associated with increased CREB (Ser 133) phosphorylation, but is independent of BDNF/TrkB signaling pathways.
    Authors: Rittase, W Bradle, Dong, Yu, Barksdale, DaRel, Galdzicki, Zygmunt, Bausch, Suzanne
    Mol Cell Neurosci, 2014-04-23;60(0):63-71.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: Control
  73. VISTA is an immune checkpoint molecule for human T cells.
    Authors: Lines J, Pantazi E, Mak J, Sempere L, Wang L, O'Connell S, Ceeraz S, Suriawinata A, Yan S, Ernstoff M, Noelle R
    Cancer Res, 2014-04-01;74(7):1924-32.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  74. The endocannabinoid/endovanilloid N-arachidonoyl dopamine (NADA) and synthetic cannabinoid WIN55,212-2 abate the inflammatory activation of human endothelial cells.
    Authors: Wilhelmsen K, Khakpour S, Tran A, Sheehan K, Schumacher M, Xu F, Hellman J
    J Biol Chem, 2014-03-18;289(19):13079-100.
    Species: Human
    Sample Types: Whole Cells
  75. Ovine carotid artery-derived cells as an optimized supportive cell layer in 2-D capillary network assays.
    Authors: Weinandy, Stefan, Babczyk, Patrick, Dreier, Agnieszk, Unger, Ronald E, Flanagan, Thomas C, Kirkpatrick, C James, Zenke, Martin, Klee, Doris, Jockenhoevel, Stefan
    PLoS ONE, 2014-03-12;9(3):e91664.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry Control
  76. Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity.
    Authors: Ramkhelawon B, Hennessy E, Menager M, Ray T, Sheedy F, Hutchison S, Wanschel A, Oldebeken S, Geoffrion M, Spiro W, Miller G, McPherson R, Rayner K, Moore K
    Nat Med, 2014-03-02;20(4):377-84.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  77. Novaferon, a novel recombinant protein produced by DNA-shuffling of IFN-alpha, shows antitumor effect in vitro and in vivo.
    Authors: Li M, Rao C, Pei D, Wang L, Li Y, Gao K, Wang M, Wang J
    Cancer Cell Int, 2014-01-27;14(1):8.
    Applications: Surface Plasmon Resonance
  78. TNF-alpha blockade induces IL-10 expression in human CD4+ T cells.
    Authors: Evans H, Roostalu U, Walter G, Gullick N, Frederiksen K, Roberts C, Sumner J, Baeten D, Gerwien J, Cope A, Geissmann F, Kirkham B, Taams L
    Nat Commun, 2014-01-01;5(0):3199.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  79. Soluble beta-amyloid Precursor Protein Alpha binds to p75 neurotrophin receptor to promote neurite outgrowth.
    Authors: Hasebe N, Fujita Y, Ueno M, Yoshimura K, Fujino Y, Yamashita T
    PLoS ONE, 2013-12-16;8(12):e82321.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: Functional ELISA
  80. Changes of peripheral TGF-beta1 depend on monocytes-derived macrophages in Huntington disease.
    Authors: Di Pardo A, Alberti S, Maglione V, Amico E, Cortes E, Elifani F, Battaglia G, Busceti C, Nicoletti F, Vonsattel J, Squitieri F
    Mol Brain, 2013-12-13;6(0):55.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry Control
  81. Role of synaptic plasticity and EphA5-ephrinA5 interaction within the ventromedial hypothalamus in response to recurrent hypoglycemia.
    Authors: Szepietowska, Barbara, Horvath, Tamas L, Sherwin, Robert S
    Diabetes, 2013-11-12;63(3):1140-7.
    Species: Rat
    Sample Types: In Vivo
    Applications: In Vivo
  82. Bromelain decreases neutrophil interactions with P-selectin, but not E-selectin, in vitro by proteolytic cleavage of P-selectin glycoprotein ligand-1.
    Authors: Banks, Jessica, Herman, Christin, Bailey, Ryan C
    PLoS ONE, 2013-11-11;8(11):e78988.
    Applications: Bioassay
  83. NKG2D triggers cytotoxicity in murine epidermal gammadelta T cells via PI3K-dependent, Syk/ZAP70-independent signaling pathway.
    Authors: Ibusuki A, Kawai K, Yoshida S, Uchida Y, Nitahara-Takeuchi A, Kuroki K, Kajikawa M, Ose T, Maenaka K, Kasahara M, Kanekura T
    J Invest Dermatol, 2013-08-20;134(2):396-404.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  84. CRTAM receptor engagement by Necl-2 on tumor cells triggers cell death of activated Vgamma9Vdelta2 T cells.
    Authors: Dessarthe B, Thedrez A, Latouche J, Cabillic F, Drouet A, Daniel P, de La Pintiere C, Catros V, Toutirais O
    J Immunol, 2013-03-25;190(9):4868-76.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  85. Blood CD4+CD45RO+CXCR5+ T cells are decreased but partially functional in signal transducer and activator of transcription 3 deficiency.
    Authors: Mazerolles F, Picard C, Kracker S, Fischer A, Durandy A
    J Allergy Clin Immunol, 2013-02-10;131(4):1146-56, 1156.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  86. EphA5-EphrinA5 interactions within the ventromedial hypothalamus influence counterregulatory hormone release and local glutamine/glutamate balance during hypoglycemia.
    Authors: Szepietowska B, Zhu W, Czyzyk J, Eid T, Sherwin R
    Diabetes, 2012-12-28;62(4):1282-8.
    Species: Rat
    Sample Types: In Vivo
  87. Up-regulation of a death receptor renders antiviral T cells susceptible to NK cell-mediated deletion.
    Authors: Peppa, Dimitra, Gill, Upkar S, Reynolds, Gary, Easom, Nicholas, Pallett, Laura J, Schurich, Anna, Micco, Lorenzo, Nebbia, Gaia, Singh, Harsimra, Adams, David H, Kennedy, Patrick, Maini, Mala K
    J Exp Med, 2012-12-17;210(1):99-114.
    Species: Human
    Sample Types: Whole Cells
    Applications: Control
  88. Interleukin-33 overexpression is associated with gamma-glutamyl transferase in biliary atresia.
    Cytokine, 2012-11-22;61(2):433-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  89. Semaphorin 6A regulates angiogenesis by modulating VEGF signaling.
    Authors: Segarra, Marta, Ohnuki, Hidetaka, Maric, Dragan, Salvucci, Ombretta, Hou, Xu, Kumar, Anil, Li, Xuri, Tosato, Giovanna
    Blood, 2012-09-24;120(19):4104-15.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  90. The alarmin IL-33 is a notch target in quiescent endothelial cells.
    Authors: Sundlisaeter E, Edelmann R, Hol J, Sponheim J, Kuchler A, Weiss M, Udalova I, Midwood K, Kasprzycka M, Haraldsen G
    Am J Pathol, 2012-07-16;181(3):1099-111.
    Species: Human
    Sample Types: Whole Cells
    Applications: Control
  91. Receptor activator of nuclear factor kappaB ligand (RANKL) protein expression by B lymphocytes contributes to ovariectomy-induced bone loss.
    Authors: Onal M, Xiong J, Chen X, Thostenson J, Almeida M, Manolagas S
    Oncogene, 2012-07-10;287(35):29851-60.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Control
  92. IL-15 Expression on RA Synovial Fibroblasts Promotes B Cell Survival.
    Authors: Benito-Miguel M, Garcia-Carmona Y, Balsa A, Bautista-Caro MB, Arroyo-Villa I, Cobo-Ibanez T, Bonilla-Hernan MG, De Ayala CP, Sanchez-Mateos P, Martin-Mola E, Miranda-Carus ME
    PLoS ONE, 2012-07-09;7(7):e40620.
    Species: Human
    Sample Types: Whole Cells
    Applications: Control
  93. DcR3 binds to ovarian cancer via heparan sulfate proteoglycans and modulates tumor cells response to platinum with corresponding alteration in the expression of BRCA1.
    BMC Cancer, 2012-05-14;12(0):176.
    Species: Human
    Sample Types: Whole Cells
    Applications: Control
  94. Identification of TLT2 as an engulfment receptor for apoptotic cells.
    Authors: de Freitas A, Banerjee S, Xie N
    J. Immunol., 2012-05-09;188(12):6381-8.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  95. The mouse IAPE endogenous retrovirus can infect cells through any of the five GPI-anchored Ephrin A proteins.
    Authors: Dewannieux M, Vernochet C, Ribet D, Bartosch B, Cosset FL, Heidmann T
    PLoS Pathog., 2011-10-20;7(10):e1002309.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Control
  96. Slit-Robo signals regulate pioneer axon pathfinding of the tract of the postoptic commissure in the mammalian forebrain.
    Authors: Ricano-Cornejo I, Altick AL, Garcia-Pena CM, Nural HF, Echevarria D, Miquelajauregui A, Mastick GS, Varela-Echavarria A
    J. Neurosci. Res., 2011-06-17;89(10):1531-41.
    Species: Mouse
    Sample Types: Whole Tissue
  97. Angiocrine factors modulate tumor proliferation and motility through EphA2 repression of Slit2 tumor suppressor function in endothelium.
    Authors: Brantley-Sieders DM, Dunaway CM, Rao M
    Cancer Res., 2010-12-08;71(3):976-87.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Control
  98. EphB signaling controls lineage plasticity of adult neural stem cell niche cells.
    Authors: Nomura T, Goritz C, Catchpole T, Henkemeyer M, Frisen J
    Cell Stem Cell, 2010-12-03;7(6):730-43.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Control
  99. Exogenous recombinant dimeric neuropilin-1 is sufficient to drive angiogenesis.
    Authors: Uniewicz KA, Cross MJ, Fernig DG
    J. Biol. Chem., 2010-10-18;286(1):12-23.
    Species: Human
    Sample Types: Whole Cells
    Applications: Control
  100. Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis.
    Authors: Sawamiphak S, Seidel S, Essmann CL, Wilkinson GA, Pitulescu ME, Acker T, Acker-Palmer A
    Nature, 2010-05-05;465(7297):487-91.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Control
  101. Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma.
    Authors: Lamprecht B, Walter K, Kreher S, Kumar R, Hummel M, Lenze D, Kochert K, Bouhlel MA, Richter J, Soler E, Stadhouders R, Johrens K, Wurster KD, Callen DF, Harte MF, Giefing M, Barlow R, Stein H, Anagnostopoulos I, Janz M, Cockerill PN, Siebert R, Dorken B, Bonifer C, Mathas S
    Nat. Med., 2010-05-02;16(5):571-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Control
  102. VEGF-A expression by HSV-1-infected cells drives corneal lymphangiogenesis.
    Authors: Wuest TR, Carr DJ
    J. Exp. Med., 2009-12-21;207(1):101-15, S1-2.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Control
  103. Scavenger receptor B2 is a cellular receptor for enterovirus 71.
    Authors: Yamayoshi S, Yamashita Y, Li J, Hanagata N, Minowa T, Takemura T, Koike S
    Nat. Med., 2009-06-21;15(7):798-801.
    Species: Human
    Sample Types: Peptide
    Applications: Bioassay
  104. Galectin-8 interacts with podoplanin and modulates lymphatic endothelial cell functions.
    Authors: Cueni LN, Detmar M
    Exp. Cell Res., 2009-03-04;315(10):1715-23.
    Species: Human
    Sample Types: Buffer
    Applications: Control
  105. Cross-linking of B7-H1 on EBV-transformed B cells induces apoptosis through reactive oxygen species production, JNK signaling activation, and fasL expression.
    Authors: Kim YS, Park GB, Lee HK, Song H, Choi IH, Lee WJ, Hur DY
    J. Immunol., 2008-11-01;181(9):6158-69.
    Species: Human
    Sample Types: Whole Cells
    Applications: Control
  106. IL-4 inhibits VLA-4 expression on Tc1 cells resulting in poor tumor infiltration and reduced therapy benefit.
    Authors: Sasaki K, Pardee AD, Okada H, Storkus WJ
    Eur. J. Immunol., 2008-10-01;38(10):2865-73.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Control
  107. p75(NTR) mediates ephrin-A reverse signaling required for axon repulsion and mapping.
    Authors: Lim YS, McLaughlin T, Sung TC, Santiago A, Lee KF, O'Leary DD
    Neuron, 2008-09-11;59(5):746-58.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Control
  108. Temporal regulation of ephrin/Eph signalling is required for the spatial patterning of the mammalian striatum.
    Authors: Passante L, Gaspard N, Degraeve M, Frisen J, Kullander K, De Maertelaer V, Vanderhaeghen P
    Development, 2008-08-28;135(19):3281-90.
    Species: Mouse
    Sample Types: Whole Tissue
  109. Blockade of EphB2 enhances neurogenesis in the subventricular zone and improves neurological function after cerebral cortical infarction in hypertensive rats.
    Authors: Xing S, He Y, Ling L, Hou Q, Yu J, Zeng J, Pei Z
    Brain Res., 2008-07-02;1230(0):237-46.
    Species: Rat
    Sample Types: In Vivo
    Applications: Control
  110. Intrinsic sensor of oncogenic transformation induces a signal for innate immunosurveillance.
    Authors: Unni AM, Bondar T, Medzhitov R
    Proc. Natl. Acad. Sci. U.S.A., 2008-01-25;105(5):1686-91.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Control
  111. Plasticity of neuron-glial interactions mediated by astrocytic EphARs.
    Authors: Nestor MW, Mok LP, Tulapurkar ME, Thompson SM
    J. Neurosci., 2007-11-21;27(47):12817-28.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Control
  112. Extracellular stimuli specifically regulate localized levels of individual neuronal mRNAs.
    Authors: Willis DE, van Niekerk EA, Sasaki Y, Mesngon M, Merianda TT, Williams GG, Kendall M, Smith DS, Bassell GJ, Twiss JL
    J. Cell Biol., 2007-09-04;178(6):965-80.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Control
  113. CD86 regulates IgG1 production via a CD19-dependent mechanism.
    Authors: Kin NW, Sanders VM
    J. Immunol., 2007-08-01;179(3):1516-23.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Control
  114. Soluble vascular endothelial growth factor receptor-1 protects mice in sepsis.
    Authors: Tsao PN, Chan FT, Wei SC, Hsieh WS, Chou HC, Su YN, Chen CY, Hsu WM, Hsieh FJ, Hsu SM
    Crit. Care Med., 2007-08-01;35(8):1955-60.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Control
  115. Global DNA methylation profiling reveals silencing of a secreted form of Epha7 in mouse and human germinal center B-cell lymphomas.
    Authors: Dawson DW, Hong JS, Shen RR, French SW, Troke JJ, Wu YZ, Chen SS, Gui D, Regelson M, Marahrens Y, Morse HC, Said J, Plass C, Teitell MA
    Oncogene, 2007-01-29;26(29):4243-52.
    Species: Human
    Sample Types: Whole Cells
    Applications: Control
  116. Nonvascular VEGF receptor 3 expression by corneal epithelium maintains avascularity and vision.
    Authors: Cursiefen C, Chen L, Saint-Geniez M, Hamrah P, Jin Y, Rashid S, Pytowski B, Persaud K, Wu Y, Streilein JW, Dana R
    Proc. Natl. Acad. Sci. U.S.A., 2006-07-18;103(30):11405-10.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Control
  117. Induction of ephrin-B1 and EphB receptors during denervation-induced plasticity in the adult mouse hippocampus.
    Authors: Wang Y, Ying GX, Liu X, Wang WY, Dong JH, Ni ZM, Zhou CF
    Eur. J. Neurosci., 2005-05-01;21(9):2336-46.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Control
  118. Nurselike cells express BAFF and APRIL, which can promote survival of chronic lymphocytic leukemia cells via a paracrine pathway distinct from that of SDF-1alpha.
    Authors: Nishio M, Endo T, Tsukada N, Ohata J, Kitada S, Reed JC, Zvaifler NJ, Kipps TJ
    Blood, 2005-04-28;106(3):1012-20.
    Species: Human
    Sample Types: Whole Cells
    Applications: Control
  119. The cytolethal distending toxin induces receptor activator of NF-kappaB ligand expression in human gingival fibroblasts and periodontal ligament cells.
    Authors: Belibasakis GN, Johansson A, Wang Y, Chen C, Kalfas S, Lerner UH
    Infect. Immun., 2005-01-01;73(1):342-51.
    Species: Human
    Sample Types: Whole Cells
    Applications: Control
  120. FGF8 dose-dependent regulation of embryonic submandibular salivary gland morphogenesis.
    Authors: Jaskoll T, Witcher D, Toreno L, Bringas P, Moon AM, Melnick M
    Dev. Biol., 2004-04-15;268(2):457-69.
    Species: Mouse
    Sample Types: Whole Cells
  121. Antiangiogenic and antitumor efficacy of EphA2 receptor antagonist.
    Authors: Dobrzanski P, Hunter K, Jones-Bolin S, Chang H, Robinson C, Pritchard S, Zhao H, Ruggeri B
    Cancer Res., 2004-02-01;64(3):910-9.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Control
  122. Wnt regulation of progenitor maturation in the cortex depends on Shh or fibroblast growth factor 2.
    Authors: Viti J, Gulacsi A, Lillien L
    J. Neurosci., 2003-07-02;23(13):5919-27.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Control
  123. Control of hippocampal dendritic spine morphology through ephrin-A3/EphA4 signaling.
    Authors: Murai KK, Nguyen LN, Irie F, Yamaguchi Y, Pasquale EB
    Nat. Neurosci., 2003-02-01;6(2):153-60.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Control

FAQs

  1. Recombinant Human IgG1 Fc Protein, CF (Catalog # 110-HG) has 4 mutations: Leu117Ala, Leu118Glu, Gly120Ala, and Thr276Ala. What is the purpose of these mutations?

    • The mutations in the 110-HG protein sequence were introduced to aid in the stability of the protein.

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Reviews for Recombinant Human IgG1 Fc Protein, CF

Average Rating: 4.6 (Based on 8 Reviews)

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Recombinant Human IgG1 Fc Protein, CF
By Anonymous on 10/06/2021
Application: Binding assay/Protein-protein interaction

Recombinant Human IgG1 Fc Protein, CF
By Anonymous on 10/26/2020
Application: Cell Adhesion
Reason for Rating: it worked well in my assay and the result was as expected

I am using it as my negative control in the cell adhesion assay.


Recombinant Human IgG1 Fc Protein, CF
By Anonymous on 08/04/2020
Application: Binding assay/Protein-protein interaction

Recombinant Human IgG1 Fc Protein, CF
By tenny tang on 12/21/2018
Application: CellProlif

Recombinant Human IgG1 Fc Protein, CF
By tenny tang on 12/07/2018
Application: CellProlif

Recombinant Human IgG1 Fc Protein, CF
By tenny tang on 10/13/2018
Application: Cell Adhesion

Recombinant Human IgG1 Fc, CF
By Anonymous on 12/08/2017
Application: Binding assay/Protein-protein interaction
Reason for Rating: Have used as a control in countless ELISA and FACs assays and have never observed non-specific binding.

Recombinant Human IgG1 Fc Protein, CF
By Anonymous on 04/21/2017