Recombinant Human Noggin Protein

Chemically-defined and scalable culture system for intestinal stem cells derived from human intestinal organoids
Authors: Kwon, O;Lee, H;Jung, J;Son, YS;Jeon, S;Yoo, WD;Son, N;Jung, KB;Choi, E;Lee, IC;Kwon, HJ;Kim, C;Lee, MO;Cho, HS;Kim, DS;Son, MY;
Nature communications
Species: Human
Sample Types: Whole Cells
Applications: Differentiation

ROR2 expression predicts human induced pluripotent stem cell differentiation into neural stem/progenitor cells and GABAergic neurons
Authors: Kuroda, T;Yasuda, S;Matsuyama, S;Miura, T;Sawada, R;Matsuyama, A;Yamamoto, Y;Morioka, MS;Kawaji, H;Kasukawa, T;Itoh, M;Akutsu, H;Kawai, J;Sato, Y;
Scientific reports
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

In vitro modeling of the human dopaminergic system using spatially arranged ventral midbrain-striatum-cortex assembloids
Authors: Reumann, D;Krauditsch, C;Novatchkova, M;Sozzi, E;Wong, SN;Zabolocki, M;Priouret, M;Doleschall, B;Ritzau-Reid, KI;Piber, M;Morassut, I;Fieseler, C;Fiorenzano, A;Stevens, MM;Zimmer, M;Bardy, C;Parmar, M;Knoblich, JA;
Nature methods
Species: Human
Sample Types: Organoids
Applications: Bioassay

Development of functional resident macrophages in human pluripotent stem cell-derived colonic organoids and human fetal colon
Authors: Múnera, JO;Kechele, DO;Bouffi, C;Qu, N;Jing, R;Maity, P;Enriquez, JR;Han, L;Campbell, I;Mahe, MM;McCauley, HA;Zhang, X;Sundaram, N;Hudson, JR;Zarsozo-Lacoste, A;Pradhan, S;Tominaga, K;Sanchez, JG;Weiss, AA;Chatuvedi, P;Spence, JR;Hachimi, M;North, T;Daley, GQ;Mayhew, CN;Hu, YC;Takebe, T;Helmrath, MA;Wells, JM;
Cell stem cell
Applications: Cell Culture

Bovine oviductal organoids: a multi-omics approach to capture the cellular and extracellular molecular response of the oviduct to heat stress
Authors: Menjivar, NG;Gad, A;Thompson, RE;Meyers, MA;Hollinshead, FK;Tesfaye, D;
BMC genomics
Species: Bovine
Sample Types: Organoids
Applications: Bioassay

Disentangling the innate immune responses of intestinal epithelial cells and lamina propria cells to Salmonella Typhimurium infection in chickens
Authors: Sutton, K;Nash, T;Sives, S;Borowska, D;Mitchell, J;Vohra, P;Stevens, MP;Vervelde, L;
Frontiers in microbiology
Species: Chicken
Sample Types: Whole Cells
Applications: Bioassay

Oncogenic KRAS drives lipo-fibrogenesis to promote angiogenesis and colon cancer progression
Authors: Hsu, WH;LaBella, KA;Lin, Y;Xu, P;Lee, R;Hsieh, CE;Yang, L;Zhou, A;Blecher, JM;Wu, CJ;Lin, K;Shang, X;Jiang, S;Spring, DJ;Xia, Y;Chen, P;Shen, JP;Kopetz, S;DePinho, RA;
Cancer discovery
Species: Xenograft
Sample Types: Whole Cells
Applications: Bioassay

An integrated organoid omics map extends modeling potential of kidney disease
Authors: Lassé, M;El Saghir, J;Berthier, CC;Eddy, S;Fischer, M;Laufer, SD;Kylies, D;Hutzfeldt, A;Bonin, LL;Dumoulin, B;Menon, R;Vega-Warner, V;Eichinger, F;Alakwaa, F;Fermin, D;Billing, AM;Minakawa, A;McCown, PJ;Rose, MP;Godfrey, B;Meister, E;Wiech, T;Noriega, M;Chrysopoulou, M;Brandts, P;Ju, W;Reinhard, L;Hoxha, E;Grahammer, F;Lindenmeyer, MT;Huber, TB;Schlüter, H;Thiel, S;Mariani, LH;Puelles, VG;Braun, F;Kretzler, M;Demir, F;Harder, JL;Rinschen, MM;
Nature communications
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Deregulation of mTORC1-TFEB axis in human iPSC model of GBA1-associated Parkinson's disease
Authors: Mubariz, F;Saadin, A;Lingenfelter, N;Sarkar, C;Banerjee, A;Lipinski, MM;Awad, O;
Frontiers in neuroscience
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Blockage of retinoic acid signaling via RAR? suppressed the proliferation of pancreatic cancer cells by arresting the cell cycle progression of the G1-S phase
Authors: Yamakawa, K;Koyanagi-Aoi, M;Machinaga, A;Kakiuchi, N;Hirano, T;Kodama, Y;Aoi, T;
Cancer cell international
Species: Human
Sample Types: Organoid
Applications: Cell Culture

A distal lung organoid model to study interstitial lung disease, viral infection and human lung development
Authors: Matkovic Leko, I;Schneider, RT;Thimraj, TA;Schrode, N;Beitler, D;Liu, HY;Beaumont, K;Chen, YW;Snoeck, HW;
Nature protocols
Species: Human
Sample Types: Organoid
Applications: Bioassay

Organoid modeling of lung-resident immune responses to SARS-CoV-2 infection
Authors: Kuo, C;Choi, S;van Unen, V;Zhang, H;Rustagi, A;Alwahabi, S;Santos, A;Chan, J;Lam, B;Solis, D;Mah, J;R�ltgen, K;Trope, W;Guh-Siesel, A;Lin, Z;Beck, A;Edwards, C;Mallajosyula, V;Martin, B;Dunn, J;Shrager, J;Baric, R;Pinsky, B;Boyd, S;Blish, C;Davis, M;
Research square
Species: Human
Sample Types: Tissue Homogenates
Applications: Bioassay

Bone Morphogenetic Protein-4 Impairs Retinal Endothelial Cell Barrier, a Potential Role in Diabetic Retinopathy
Authors: Darwish, NHE;Hussein, KA;Elmasry, K;Ibrahim, AS;Humble, J;Moustafa, M;Awadalla, F;Al-Shabrawey, M;
Cells
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Vibrio cholerae biofilms use modular adhesins with glycan-targeting and nonspecific surface binding domains for colonization
Authors: X Huang, T Nero, R Weeraseker, KH Matej, A Hinbest, Z Jiang, RF Lee, L Wu, C Chak, J Nijjer, I Gibaldi, H Yang, N Gamble, WL Ng, SA Malaker, K Sumigray, R Olson, J Yan
Nature Communications, 2023-04-13;14(1):2104.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Activation of AKT induces EZH2-mediated beta-catenin trimethylation in colorectal cancer
Authors: AH Ghobashi, TT Vuong, JW Kimani, HM O'Hagan
bioRxiv : the preprint server for biology, 2023-02-04;0(0):.
Species: Human
Sample Types: Organoids
Applications: Bioassay

Combined PD-1, BRAF and MEK inhibition in BRAFV600E colorectal cancer: a phase 2 trial
Authors: J Tian, JH Chen, SX Chao, K Pelka, M Giannakis, J Hess, K Burke, V Jorgji, P Sindurakar, J Braverman, A Mehta, T Oka, M Huang, D Lieb, M Spurrell, JN Allen, TA Abrams, JW Clark, AC Enzinger, PC Enzinger, SJ Klempner, NJ McCleary, JA Meyerhardt, DP Ryan, MB Yurgelun, K Kanter, EE Van Sevent, I Baiev, G Chi, J Jarnagin, WB Bradford, E Wong, AG Michel, IJ Fetter, G Siravegna, AJ Gemma, A Sharpe, S Demehri, R Leary, CD Campbell, O Yilmaz, GA Getz, AR Parikh, N Hacohen, RB Corcoran
Nature Medicine, 2023-01-26;0(0):.
Species: Human
Sample Types: Organoids
Applications: Bioassay

Epigenetic and transcriptional regulations prime cell fate before division during human pluripotent stem cell differentiation
Authors: P Madrigal, S Deng, Y Feng, S Militi, KJ Goh, R Nibhani, R Grandy, A Osnato, D Ortmann, S Brown, S Pauklin
Nature Communications, 2023-01-25;14(1):405.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Expansion of ventral foregut is linked to changes in the enhancer landscape for organ-specific differentiation
Authors: YF Wong, Y Kumar, M Proks, JAR Herrera, MM Rothová, RS Monteiro, S Pozzi, RE Jennings, NA Hanley, WA Bickmore, JM Brickman
Nature Cell Biology, 2023-01-23;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Hypoxia-tolerant apical-out intestinal organoids to model host-microbiome interactions
Authors: P Kakni, B Jutten, D Teixeira O, J Penders, R Truckenmül, P Habibovic, S Giselbrech
Journal of tissue engineering, 2023-01-18;14(0):2041731422114.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Targeting TBK1 to overcome resistance to cancer immunotherapy
Authors: Y Sun, OY Revach, S Anderson, EA Kessler, CH Wolfe, A Jenney, CE Mills, EJ Robitschek, TGR Davis, S Kim, A Fu, X Ma, J Gwee, P Tiwari, PP Du, P Sindurakar, J Tian, A Mehta, AM Schneider, K Yizhak, M Sade-Feldm, T LaSalle, T Sharova, H Xie, S Liu, WA Michaud, R Saad-Beret, KB Yates, A Iracheta-V, JKE Spetz, X Qin, KA Sarosiek, G Zhang, JW Kim, MY Su, AM Cicerchia, MQ Rasmussen, SJ Klempner, D Juric, SI Pai, DM Miller, A Giobbie-Hu, JH Chen, K Pelka, DT Frederick, S Stinson, E Ivanova, AR Aref, CP Paweletz, DA Barbie, DR Sen, DE Fisher, RB Corcoran, N Hacohen, PK Sorger, KT Flaherty, GM Boland, RT Manguso, RW Jenkins
Nature, 2023-01-12;0(0):.
Species: Human
Sample Types: Organoids
Applications: Bioassay

Programming Multicellular Assembly with Synthetic Cell Adhesion Molecules
Authors: AJ Stevens, AR Harris, J Gerdts, KH Kim, C Trentesaux, JT Ramirez, WL McKeithan, F Fattahi, OD Klein, DA Fletcher, WA Lim
Nature, 2022-12-12;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Generation and cryopreservation of feline oviductal organoids
Authors: RE Thompson, MA Meyers, C Premananda, FK Hollinshea
Theriogenology, 2022-11-17;196(0):167-173.
Species: Feline
Sample Types: Organoids
Applications: Bioassay

Membrane Attack Complex Mediates Retinal Pigment Epithelium Cell Death in Stargardt Macular Degeneration
Authors: ESY Ng, N Kady, J Hu, A Dave, Z Jiang, J Pei, MB Gorin, A Matynia, RA Radu
Cells, 2022-11-02;11(21):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Quantitative analysis of transcriptome dynamics provides novel insights into developmental state transitions
Authors: K Johnson, S Freedman, R Braun, C LaBonne
BMC Genomics, 2022-10-23;23(1):723.
Species: Frog
Sample Types:
Applications: Bioassay

Modeling native and seeded Synuclein aggregation and related cellular dysfunctions in dopaminergic neurons derived by a new set of isogenic iPSC lines with SNCA multiplications
Authors: A Iannielli, M Luoni, SG Giannelli, R Ferese, G Ordazzo, M Fossati, A Raimondi, F Opazo, O Corti, JHM Prehn, S Gambardell, R Melki, V Broccoli
Cell Death & Disease, 2022-10-19;13(10):881.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Antibody targeting of E3 ubiquitin ligases for receptor degradation
Authors: H Marei, WK Tsai, YS Kee, K Ruiz, J He, C Cox, T Sun, S Penikalapa, P Dwivedi, M Choi, D Kan, P Saenz-Lope, K Dorighi, P Zhang, YT Kschonsak, N Kljavin, D Amin, I Kim, AG Mancini, T Nguyen, C Wang, E Janezic, A Doan, E Mai, H Xi, C Gu, M Heinlein, B Biehs, J Wu, I Lehoux, S Harris, L Comps-Agra, D Seshasayee, FJ de Sauvage, M Grimmer, J Li, NJ Agard, F de Sousa E
Nature, 2022-09-21;610(7930):182-189.
Species: Human
Sample Types: Organoid
Applications: Bioassay

Directed differentiation of human pluripotent stem cells into diverse organ-specific mesenchyme of the digestive and respiratory systems
Authors: K Kishimoto, K Iwasawa, A Sorel, C Ferran-Her, L Han, M Morimoto, JM Wells, T Takebe, AM Zorn
Nature Protocols, 2022-08-17;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Fluvastatin promotes chondrogenic differentiation of adipose-derived mesenchymal stem cells by inducing bone morphogenetic protein 2
Authors: M Kuwahara, Y Akasaki, N Goto, I Kurakazu, T Sueishi, M Toya, T Uchida, T Tsutsui, R Hirose, H Tsushima, Y Nakashima
Bmc Pharmacology & Toxicology, 2022-08-09;23(1):61.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Sox2 in the dermal papilla regulates hair follicle pigmentation
Authors: KJ Ng, J Lim, YN Tan, D Quek, Z Lim, N Pantelirei, C Clavel
Oncogene, 2022-07-19;40(3):111100.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Early Signs of Molecular Defects in iPSC-Derived Neural Stems Cells from Patients with Familial Parkinson's Disease
Authors: E Akrioti, T Karamitros, P Gkaravelas, G Kouroupi, R Matsas, E Taoufik
Biomolecules, 2022-06-23;12(7):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Delamination of trophoblast-like syncytia from the amniotic ectodermal analogue in human primed embryonic stem cell-based differentiation model
Authors: M Ohgushi, N Taniyama, A Vandenbon, M Eiraku
Cell Reports, 2022-06-21;39(12):110973.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Equine Oviductal Organoid Generation and Cryopreservation
Authors: RE Thompson, MA Meyers, DNR Veeramacha, BS Pukazhenth, FK Hollinshea
Methods and protocols, 2022-06-15;5(3):.
Species: Equine
Sample Types: Organoid
Applications: Bioassay

Patient-derived micro-organospheres enable clinical precision oncology
Authors: S Ding, C Hsu, Z Wang, NR Natesh, R Millen, M Negrete, N Giroux, GO Rivera, A Dohlman, S Bose, T Rotstein, K Spiller, A Yeung, Z Sun, C Jiang, R Xi, B Wilkin, PM Randon, I Williamson, DA Nelson, D Delubac, S Oh, G Rupprecht, J Isaacs, J Jia, C Chen, JP Shen, S Kopetz, S McCall, A Smith, N Gjorevski, AC Walz, S Antonia, E Marrer-Ber, H Clevers, D Hsu, X Shen
Cell Stem Cell, 2022-05-03;0(0):.
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay

Modeling Pancreatic Cancer with Patient-Derived Organoids Integrating Cancer-Associated Fibroblasts
Authors: YH Go, WH Choi, WJ Bae, SI Jung, CH Cho, SA Lee, JS Park, JM Ahn, SW Kim, KJ Lee, D Lee, J Yoo
Cancers, 2022-04-21;14(9):.
Species: Human
Sample Types: Organoids
Applications: Bioassay

ATG7-mediated autophagy facilitates embryonic stem cell exit from naive pluripotency and marks commitment to differentiation
Authors: J Zhou, H He, JJ Zhang, X Liu, W Yao, C Li, T Xu, SY Yin, DY Wu, CL Dou, Q Li, J Xiang, WJ Xiong, LY Wang, JM Tang, Z Xue, X Zhang, YL Miao
Autophagy, 2022-04-10;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Tissue extracellular matrix hydrogels as alternatives to Matrigel for culturing gastrointestinal organoids
Authors: S Kim, S Min, YS Choi, SH Jo, JH Jung, K Han, J Kim, S An, YW Ji, YG Kim, SW Cho
Nature Communications, 2022-03-30;13(1):1692.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Pterostilbene in Combination With Mitochondrial Cofactors Improve Mitochondrial Function in Cellular Models of Mitochondrial Diseases
Authors: JM Suárez-Riv, CJ Pastor-Mal, A Romero-Gon, D Gómez-Fern, S Povea-Cabe, M Álvarez-Có, I Villalón-G, M Talaverón-, A Suárez-Car, M Munuera-Ca, JA Sánchez-Al
Frontiers in Pharmacology, 2022-03-18;13(0):862085.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Epithelial-derived factors induce muscularis mucosa of human induced pluripotent stem cell-derived gastric organoids
Authors: K Uehara, M Koyanagi-A, T Koide, T Itoh, T Aoi
Stem Cell Reports, 2022-03-03;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

OncoSNIPE� Study Protocol, a study of molecular profiles associated with development of resistance in solid cancer patients
Authors: S Vachenc, J Gobbo, SE Moujarrebe, I Desmoulins, M Gilabert, M Beau-Falle, E Mitry, N Girard, A Bertaut, N Dusetti, JL Iovanna, R Yousfi, F Pierrat, R Bruno, A Cueff, R Boidot, P Genne
BMC Cancer, 2022-01-06;22(1):41.
Species: Human
Sample Types: Organoid
Applications: Bioassay

Intracameral Microimaging of Maturation of Human iPSC Derivatives into Islet Endocrine Cells
Authors: K Zhao, Y Shi, J Yu, L Yu, A Mael, Y Li, A Kolton, T Joyce, J Odorico, PO Berggren, SN Yang
Cell Transplantation, 2022-01-01;31(0):9636897211066.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Programming Multicellular Assembly with Synthetic Cell Adhesion Molecules
Authors: AJ Stevens, AR Harris, J Gerdts, KH Kim, C Trentesaux, JT Ramirez, WL McKeithan, F Fattahi, OD Klein, DA Fletcher, WA Lim
Nature, 2022;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Human iPSC-derived fallopian tube organoids with BRCA1 mutation recapitulate early-stage carcinogenesis
Authors: N Yucer, R Ahdoot, MJ Workman, AH Laperle, MS Recouvreux, K Kurowski, DJ Naboulsi, V Liang, Y Qu, JT Plummer, SA Gayther, S Orsulic, BY Karlan, CN Svendsen
Cell Reports, 2021-12-28;37(13):110146.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Epithelial phenotype restoring drugs suppress macular degeneration phenotypes in an iPSC model
Authors: R Sharma, A George, M Nimmagadda, D Ortolan, BS Karla, Z Qureshy, D Bose, R Dejene, G Liang, Q Wan, J Chang, BS Jha, O Memon, KJ Miyagishim, A Rising, M Lal, E Hanson, R King, MM Campos, M Ferrer, J Amaral, D McGaughey, K Bharti
Nature Communications, 2021-12-15;12(1):7293.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Local non-pituitary growth hormone is induced with aging and facilitates epithelial damage
Authors: V Chesnokova, S Zonis, A Apostolou, HQ Estrada, S Knott, K Wawrowsky, K Michelsen, A Ben-Shlomo, R Barrett, V Gorbunova, K Karalis, S Melmed
Cell Reports, 2021-12-14;37(11):110068.
Species: Human
Sample Types: Organoid
Applications: Bioassay

Relevance of biopsy-derived pancreatic organoids in the development of efficient transcriptomic signatures to predict adjuvant chemosensitivity in pancreatic cancer
Authors: R Nicolle, O Gayet, M Bigonnet, J Roques, B Chanez, F Puleo, J Augustin, JF Emile, M Svrcek, T Arsenijevi, P Hammel, V Rebours, M Giovannini, P Grandval, L Dahan, V Moutardier, E Mitry, JL Van Laethe, JB Bachet, J Cros, J Iovanna, NJ Dusetti
Translational Oncology, 2021-12-11;16(0):101315.
Species: Human
Sample Types: Organoid
Applications: Bioassay

Reprogramming Human Adult Fibroblasts into GABAergic Interneurons
Authors: A Bruzelius, S Kidnapilla, J Drouin-Oue, T Stoker, RA Barker, D Rylander O
Cells, 2021-12-08;10(12):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Functional human gastrointestinal organoids can be engineered from three primary germ layers derived separately from pluripotent stem cells
Authors: AK Eicher, DO Kechele, N Sundaram, HM Berns, HM Poling, LE Haines, JG Sanchez, K Kishimoto, M Krishnamur, L Han, AM Zorn, MA Helmrath, JM Wells
Cell Stem Cell, 2021-12-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Novel chicken two-dimensional intestinal model comprising all key epithelial cell types and a mesenchymal sub-layer
Authors: B Orr, K Sutton, S Christian, T Nash, H Niemann, LL Hansen, MJ McGrew, SR Jensen, L Vervelde
Veterinary research, 2021-11-24;52(1):142.
Species: Chicken
Sample Types: Whole Cells
Applications: Bioassay

Establishment of human induced trophoblast stem-like cells from term villous cytotrophoblasts
Authors: T Bai, CY Peng, I Aneas, N Sakabe, DF Requena, C Billstrand, M Nobrega, C Ober, M Parast, JA Kessler
Stem Cell Research, 2021-08-19;56(0):102507.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Generation of equine enteroids and enteroid-derived 2D monolayers that are responsive to microbial mimics
Authors: S Hellman
Veterinary research, 2021-08-14;52(1):108.
Species: Equine
Sample Types: Organoid
Applications: Bioassay

Pluripotent stem cell-derived corneal endothelial cells as an alternative to donor corneal endothelium in keratoplasty
Authors: M Ali, SY Khan, JD Gottsch, EK Hutchinson, A Khan, SA Riazuddin
Stem Cell Reports, 2021-08-05;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A pan-cancer organoid platform for precision medicine
Authors: BM Larsen, M Kannan, LF Langer, BD Leibowitz, A Bentaieb, A Cancino, I Dolgalev, BE Drummond, JR Dry, CS Ho, G Khullar, BA Krantz, B Mapes, KE McKinnon, J Metti, JF Perera, TA Rand, V Sanchez-Fr, JM Shaxted, MM Stein, MA Streit, YC Tan, Y Zhang, E Zhao, J Venkataram, MC Stumpe, JA Borgia, A Masood, DVT Catenacci, JV Mathews, DB Gursel, JJ Wei, TH Welling, DM Simeone, KP White, AA Khan, C Igartua, AA Salahudeen
Cell Reports, 2021-07-27;36(4):109429.
Species: Human
Sample Types: Organoid
Applications: Bioassay

Porcine small intestinal organoids as a model to explore ETEC-host interactions in the gut
Authors: B Vermeire, LM Gonzalez, RJJ Jansens, E Cox, B Devriendt
Veterinary research, 2021-06-26;52(1):94.
Species: Porcine
Sample Types: Organoids
Applications: Bioassay

Exploring the Complementarity of Pancreatic Ductal Adenocarcinoma Preclinical Models
Authors: O Hoare, N Fraunhoffe, A Elkaoutari, O Gayet, M Bigonnet, J Roques, R Nicolle, C McGuckin, N Forraz, E Sohier, L Tonon, P Wajda, S Boyault, V Attignon, S Tabone-Egl, S Barbier, C Mignard, O Duchamp, J Iovanna, NJ Dusetti
Cancers, 2021-05-19;13(10):.
Species: Human
Sample Types: Organoid
Applications: Bioassay

MeCP2 controls neural stem cell fate specification through miR-199a-mediated inhibition of BMP-Smad signaling
Authors: H Nakashima, K Tsujimura, K Irie, T Imamura, CA Trujillo, M Ishizu, M Uesaka, M Pan, H Noguchi, K Okada, K Aoyagi, T Andoh-Noda, H Okano, AR Muotri, K Nakashima
Cell Reports, 2021-05-18;35(7):109124.
Species: Human
Sample Types: Organoid
Applications: Bioassay

Measuring the elastic modulus of soft culture surfaces and three-dimensional hydrogels using atomic force microscopy
Authors: MDA Norman, SA Ferreira, GM Jowett, L Bozec, E Gentleman
Nature Protocols, 2021-04-14;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

APOE2 mitigates disease-related phenotypes in an isogenic hiPSC-based model of Alzheimer's disease
Authors: N Brookhouse, S Raman, C Frisch, G Srinivasan, DA Brafman
Molecular Psychiatry, 2021-04-09;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Rational design and optimization of synthetic gene switches for controlling cell-fate decisions in pluripotent stem cells
Authors: V Haellman, P Saxena, Y Jiang, M Fussenegge
Metabolic engineering, 2021-03-17;65(0):99-110.
Species: N/A
Sample Types: Plasmid
Applications: Bioassay

Farnesyl dimethyl chromanol targets colon cancer stem cells and prevents colorectal cancer metastasis
Authors: K Husain, D Coppola, CS Yang, MP Malafa
Scientific Reports, 2021-01-26;11(1):2185.
Species: Human
Sample Types: Organoid
Applications: Bioassay

A quantitative model of cellular decision making in direct neuronal reprogramming
Authors: A Merlevede, EM Legault, V Drugge, RA Barker, J Drouin-Oue, V Olariu
Scientific Reports, 2021-01-15;11(1):1514.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Induced organoids derived from patients with ulcerative colitis recapitulate colitic reactivity
Authors: SK Sarvestani, S Signs, B Hu, Y Yeu, H Feng, Y Ni, DR Hill, RC Fisher, S Ferrandon, RK DeHaan, J Stiene, M Cruise, TH Hwang, X Shen, JR Spence, EH Huang
Nature Communications, 2021-01-11;12(1):262.
Species: Human
Sample Types: Organoid
Applications: Bioassay

Modeling Intestinal Epithelial Response to Interferon-&gamma in Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids
Authors: MJ Workman, E Troisi, SR Targan, CN Svendsen, RJ Barrett
International Journal of Molecular Sciences, 2020-12-30;22(1):.
Species: Human
Sample Types: Organoid
Applications: Bioassay

Kinetic modeling of stem cell transcriptome dynamics to identify regulatory modules of normal and disturbed neuroectodermal differentiation
Authors: J Meisig, N Dreser, M Kapitza, M Henry, T Rotshteyn, J Rahnenführ, JG Hengstler, A Sachinidis, T Waldmann, M Leist, N Blüthgen
Nucleic Acids Res, 2020-12-16;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Transplantation of Neural Precursors Derived from Induced Pluripotent Cells Preserve Perineuronal Nets and Stimulate Neural Plasticity in ALS Rats
Authors: S Forostyak, O Forostyak, JCF Kwok, N Romanyuk, M Rehorova, J Kriska, G Dayanithi, R Raha-Chowd, P Jendelova, M Anderova, JW Fawcett, E Sykova
International Journal of Molecular Sciences, 2020-12-16;21(24):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

A microfluidics-based stem cell model of early post-implantation human development
Authors: Y Zheng, Y Shao, J Fu
Nature Protocols, 2020-12-11;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Using systems medicine to identify a therapeutic agent with potential for repurposing in inflammatory bowel disease
Authors: K Lloyd, S Papoutsopo, E Smith, P Stegmaier, F Bergey, L Morris, M Kittner, H England, D Spiller, MHR White, CA Duckworth, BJ Campbell, V Poroikov, VAP Martins Do, A Kel, W Muller, DM Pritchard, C Probert, MD Burkitt, SysmedIBD
Dis Model Mech, 2020-11-27;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Dedifferentiation and neuronal repression define familial Alzheimer's disease
Authors: AB Caldwell, Q Liu, GP Schroth, DR Galasko, SH Yuan, SL Wagner, S Subramania
Sci Adv, 2020-11-13;6(46):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Direct Conversion of Human Stem Cell-Derived Glial Progenitor Cells into GABAergic Interneurons
Authors: J Giacomoni, A Bruzelius, CA Stamouli, D Rylander O
Cells, 2020-11-10;9(11):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The Fragile X Mental Retardation Protein regulates RIP1K and colorectal cancer resistance to necroptosis
Authors: A Di Grazia, I Marafini, G Pedini, D Di Fusco, F Laudisi, V Dinallo, E Rosina, C Stolfi, E Franzè, P Sileri, G Sica, G Monteleone, C Bagni, I Monteleone
Cell Mol Gastroenterol Hepatol, 2020-10-19;0(0):.
Species: Human
Sample Types: Organoid
Applications: Bioassay

Direct Reprogramming of Human Fetal- and Stem Cell-Derived Glial Progenitor Cells into Midbrain Dopaminergic Neurons
Authors: S Nolbrant, J Giacomoni, DB Hoban, A Bruzelius, M Birtele, D Chandler-M, M Pereira, DR Ottosson, SA Goldman, M Parmar
Stem Cell Reports, 2020-09-24;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Single cell transcriptomics identifies a signaling network coordinating endoderm and mesoderm diversification during foregut organogenesis
Authors: L Han, P Chaturvedi, K Kishimoto, H Koike, T Nasr, K Iwasawa, K Giesbrecht, PC Witcher, A Eicher, L Haines, Y Lee, JM Shannon, M Morimoto, JM Wells, T Takebe, AM Zorn
Nat Commun, 2020-08-27;11(1):4158.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Generation of Functional Brown Adipocytes from Human Pluripotent Stem Cells via Progression through a Paraxial Mesoderm State
Authors: L Zhang, J Avery, A Yin, AM Singh, TS Cliff, H Yin, S Dalton
Cell Stem Cell, 2020-08-11;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Mapping developmental trajectories and subtype diversity of normal and glaucomatous human retinal ganglion cells by single-cell transcriptome analysis
Authors: P Teotia, M Niu, I Ahmad
Stem Cells, 2020-06-18;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Asynchronous mixing of kidney progenitor cells potentiates nephrogenesis in organoids.
Authors: Kumar Gupta A, Sarkar P, Wertheim J, Pan X, Carroll T, Oxburgh L
Commun Biol, 2020-05-11;3(1):231.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development
Authors: NK Vinckier, NA Patel, RJ Geusz, A Wang, J Wang, I Matta, AR Harrington, M Wortham, N Wetton, J Wang, US Jhala, MG Rosenfeld, CW Benner, HP Shih, M Sander
Nat Commun, 2020-04-29;11(1):2082.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

GATA3 Mediates a Fast, Irreversible Commitment to BMP4-Driven Differentiation in Human Embryonic Stem Cells
Authors: A Gunne-Brad, A Sullivan, B Gharibi, RSM Sheriff, A Maity, YF Wang, A Edwards, M Jiang, M Howell, R Goldstone, R Wollman, P East, SDM Santos
Cell Stem Cell, 2020-04-16;26(5):693-706.e9.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Generation of intestinal organoids derived from human pluripotent stem cells for drug testing
Authors: S Yoshida, H Miwa, T Kawachi, S Kume, K Takahashi
Sci Rep, 2020-04-06;10(1):5989.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Canonical Wnt signaling promotes pacemaker cell specification of cardiac mesodermal cells derived from mouse and human embryonic stem cells
Authors: W Liang, P Han, EH Kim, J Mak, R Zhang, AG Torrente, JI Goldhaber, E Marbán, HC Cho
Stem Cells, 2019-12-30;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Differential susceptibility of human neural progenitors and neurons to ischaemic injury
Authors: Y Liu, AE Michalska, M Dottori, E Eaton, JM Courtney, A Antonic, DW Howells
Brain Res. Bull., 2019-12-16;156(0):25-32.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Organotypic Cocultures of Human Pluripotent Stem Cell Derived-Neurons with Mammalian Inner Ear Hair Cells and Cochlear Nucleus Slices
Authors: T Hyakumura, S McDougall, S Finch, K Needham, M Dottori, BA Nayagam
Stem Cells Int, 2019-11-20;2019(0):8419493.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Oligodendrocyte Intrinsic miR-27a Controls Myelination and Remyelination
Authors: A Tripathi, C Volsko, JP Garcia, E Agirre, KC Allan, PJ Tesar, BD Trapp, G Castelo-Br, FJ Sim, R Dutta
Cell Rep, 2019-10-22;29(4):904-919.e9.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Activin A receptor type 1-mediated BMP signaling regulates RANKL-induced osteoclastogenesis via canonical SMAD signaling pathway
Authors: M Omi, V Kaartinen, Y Mishina
J. Biol. Chem., 2019-10-16;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Sufu- and Spop-mediated downregulation of Hedgehog signaling promotes beta cell differentiation through organ-specific niche signals
Authors: T Yung, F Poon, M Liang, S Coquenlorg, EC McGaugh, CC Hui, MD Wilson, MC Nostro, TH Kim
Nat Commun, 2019-10-11;10(1):4647.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

BMP signaling mediates glioma stem cell quiescence and confers treatment resistance in glioblastoma
Authors: R Sachdeva, M Wu, K Johnson, H Kim, A Celebre, U Shahzad, MS Graham, JA Kessler, JH Chuang, J Karamchand, M Bredel, R Verhaak, S Das
Sci Rep, 2019-10-10;9(1):14569.
Species: Human
Sample Types: Whole Cells
Applications: Tissue Culture

Targeting chemoresistant colorectal cancer via systemic administration of a BMP7 variant
Authors: V Veschi, LR Mangiapane, A Nicotra, S Di Franco, E Scavo, T Apuzzo, DS Sardina, M Fiori, A Benfante, ML Colorito, G Cocorullo, F Giuliante, C Cipolla, G Pistone, MR Bongiorno, A Rizzo, CM Tate, X Wu, S Rowlinson, LF Stancato, M Todaro, R De Maria, G Stassi
Oncogene, 2019-10-07;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Human induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure
Authors: V Lungova, X Chen, Z Wang, C Kendziorsk, SL Thibeault
Nat Commun, 2019-09-24;10(1):4161.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Controlled modelling of human epiblast and amnion development using stem cells
Authors: Y Zheng, X Xue, Y Shao, S Wang, SN Esfahani, Z Li, JM Muncie, JN Lakins, VM Weaver, DL Gumucio, J Fu
Nature, 2019-09-11;573(7774):421-425.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Rfx6 promotes the differentiation of peptide-secreting enteroendocrine cells while�repressing genetic programs controlling�serotonin production
Authors: J Piccand, C Vagne, F Blot, A Meunier, A Beucher, P Strasser, ML Lund, S Ghimire, L Nivlet, C Lapp, N Petersen, MS Engelstoft, C Thibault-C, C Keime, SJ Correa, V Schreiber, N Molina, TW Schwartz, A De Arcange, G Gradwohl
Mol Metab, 2019-08-13;29(0):24-39.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

Patient-derived pancreas-on-a-chip to model cystic fibrosis-related disorders
Authors: K Shik Mun, K Arora, Y Huang, F Yang, S Yarlagadda, Y Ramananda, M Abu-El-Hai, JJ Palermo, BN Appakalai, JD Nathan, AP Naren
Nat Commun, 2019-07-16;10(1):3124.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Blockade of STAT3 Causes Severe In Vitro and In Vivo Maturation Defects in Intestinal Organoids Derived from Human Embryonic Stem Cells
Authors: KB Jung, O Kwon, MO Lee, H Lee, YS Son, O Habib, JH Oh, HS Cho, CR Jung, J Kim, MY Son
J Clin Med, 2019-07-04;8(7):.
Species: Human
Sample Types: Organoid, Whole Cells
Applications: Bioassay

Examining the fundamental biology of a novel population of directly reprogrammed human neural precursor cells
Authors: JE Ahlfors, A Azimi, R El-Ayoubi, A Velumian, I Vonderwald, C Boscher, O Mihai, S Mani, M Samoilova, M Khazaei, MG Fehlings, CM Morshead
Stem Cell Res Ther, 2019-06-13;10(1):166.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Gain of 20q11.21 in Human Pluripotent Stem Cells Impairs TGF-?-Dependent Neuroectodermal Commitment
Authors: C Markouli, EC De Deckers, M Regin, HT Nguyen, F Zambelli, A Keller, D Dziedzicka, J De Kock, L Tilleman, F Van Nieuwe, L Franceschi, K Sermon, M Geens, C Spits
Stem Cell Reports, 2019-06-06;13(1):163-176.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Medial artery calcification increases neointimal hyperplasia after balloon injury
Authors: AP Marshall, W Luo, XL Wang, T Lin, Y Cai, RJ Guzman
Sci Rep, 2019-06-03;9(1):8193.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

Noggin depletion in adipocytes promotes obesity in mice
Authors: AM Blázquez-M, M Jumabay, P Rajbhandar, T Sallam, Y Guo, J Yao, L Vergnes, K Reue, L Zhang, Y Yao, AM Fogelman, P Tontonoz, AJ Lusis, X Wu, KI Boström
Mol Metab, 2019-04-10;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Point mutations in the PDX1 transactivation domain impair human ?-cell development and function
Authors: X Wang, M Sterr, Ansarullah, I Burtscher, A Böttcher, J Beckenbaue, J Siehler, T Meitinger, HU Häring, H Staiger, FM Cernilogar, G Schotta, M Irmler, J Beckers, CVE Wright, M Bakhti, H Lickert
Mol Metab, 2019-03-20;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Differentiation, Differentiation

Brain-stiffness-mimicking tilapia collagen gel promotes the induction of dorsal cortical neurons from human pluripotent stem cells
Authors: M Iwashita, H Ohta, T Fujisawa, M Cho, M Ikeya, S Kidoaki, Y Kosodo
Sci Rep, 2019-02-28;9(1):3068.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Excess growth hormone suppresses DNA damage repair in epithelial cells
Authors: V Chesnokova, S Zonis, R Barrett, H Kameda, K Wawrowsky, A Ben-Shlomo, M Yamamoto, J Gleeson, C Bresee, V Gorbunova, S Melmed
JCI Insight, 2019-02-07;4(3):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Generation of lung organoids from human pluripotent stem cells in vitro
Authors: AJ Miller, BR Dye, D Ferrer-Tor, DR Hill, AW Overeem, LD Shea, JR Spence
Nat Protoc, 2019-02-01;14(2):518-540.
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay

The Effect of iPS-Derived Neural Progenitors Seeded on Laminin-Coated pHEMA-MOETACl Hydrogel with Dual Porosity in a Rat Model of Chronic Spinal Cord Injury
Authors: J Ruzicka, N Romanyuk, K Jirakova, A Hejcl, O Janouskova, LU Machova, M Bochin, M Pradny, L Vargova, P Jendelova
Cell Transplant, 2019-01-18;0(0):9636897188237.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Structurally Conserved Primate LncRNAs Are Transiently Expressed during Human Cortical Differentiation and Influence Cell-Type-Specific Genes
Authors: AR Field, FMJ Jacobs, IT Fiddes, APR Phillips, AM Reyes-Orti, E LaMontagne, L Whitehead, V Meng, JL Rosenkrant, M Olsen, M Hauessler, S Katzman, SR Salama, D Haussler
Stem Cell Reports, 2019-01-10;12(2):245-257.
Species: Human, Primate - Macaca mulatta (Rhesus Macaque), Primate - Pan troglodytes (Chimpanzee), Primate - Pongo (Orangutan)
Sample Types: Whole Cells
Applications: Bioassay

High-throughput screens for agonists of bone morphogenetic protein (BMP) signaling identify potent benzoxazole compounds
Authors: STJ Bradford, EJ Ranghini, E Grimley, PH Lee, GR Dressler
J. Biol. Chem., 2019-01-02;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Generation of human antral and fundic gastric organoids from pluripotent stem cells
Authors: TR Broda, KW McCracken, JM Wells
Nat Protoc, 2019-01-01;14(1):28-50.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Pancreatic Cell Fate Determination Relies on Notch Ligand Trafficking by NFIA
Authors: MA Scavuzzo, J Chmielowie, D Yang, K Wamble, LS Chaboub, L Duraine, B Tepe, SM Glasgow, BR Arenkiel, C Brou, B Deneen, M Borowiak
Cell Rep, 2018-12-26;25(13):3811-3827.e7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Expression of the human antimicrobial peptide ?-defensin-1 is repressed by the EGFR-ERK-MYC axis in colonic epithelial cells
Authors: C Bonamy, E Sechet, A Amiot, A Alam, M Mourez, L Fraisse, PJ Sansonetti, B Sperandio
Sci Rep, 2018-12-21;8(1):18043.
Species: Human
Sample Types: Organoids
Applications: Bioassay

A transient DMSO treatment increases the differentiation potential of human pluripotent stem cells through the Rb family
Authors: J Li, C Narayanan, J Bian, D Sambo, T Brickler, W Zhang, S Chetty
PLoS ONE, 2018-12-12;13(12):e0208110.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Lysosomal and network alterations in human mucopolysaccharidosis type VII iPSC-derived neurons
Authors: N Bayó-Puxan, AP Terrasso, S Creyssels, D Simão, C Begon-Pesc, M Lavigne, S Salinas, F Bernex, A Bosch, V Kalatzis, T Levade, AM Cuervo, P Lory, A Consiglio, C Brito, EJ Kremer
Sci Rep, 2018-11-09;8(1):16644.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa
Authors: A Buskin, L Zhu, V Chichagova, B Basu, S Mozaffari-, D Dolan, A Droop, J Collin, R Bronstein, S Mehrotra, M Farkas, G Hilgen, K White, KT Pan, A Treumann, D Hallam, K Bialas, G Chung, C Mellough, Y Ding, N Krasnogor, S Przyborski, S Zwolinski, J Al-Aama, S Alharthi, Y Xu, G Wheway, K Szymanska, M McKibbin, CF Inglehearn, DJ Elliott, S Lindsay, RR Ali, DH Steel, L Armstrong, E Sernagor, H Urlaub, E Pierce, R Lührmann, SN Grellschei, CA Johnson, M Lako
Nat Commun, 2018-10-12;9(1):4234.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Natural molecules induce and synergize to boost expression of the human antimicrobial peptide ?-defensin-3
Authors: E Sechet, E Telford, C Bonamy, PJ Sansonetti, B Sperandio
Proc. Natl. Acad. Sci. U.S.A., 2018-10-01;0(0):.
Species: Human
Sample Types: Organoids
Applications: Bioassay

3D Modeling of Esophageal Development using Human PSC-Derived Basal Progenitors Reveals a Critical Role for Notch Signaling
Authors: Y Zhang, Y Yang, M Jiang, SX Huang, W Zhang, D Al Alam, S Danopoulos, M Mori, YW Chen, R Balasubram, SM Chuva de S, C Serra, M Bialecka, E Kim, S Lin, ALR Toste de C, PN Riccio, WV Cardoso, X Zhang, HW Snoeck, J Que
Cell Stem Cell, 2018-09-20;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

PEG-4MAL hydrogels for human organoid generation, culture, and in vivo delivery
Authors: R Cruz-Acuña, M Quirós, S Huang, D Siuda, JR Spence, A Nusrat, AJ García
Nat Protoc, 2018-09-01;0(0):.
Species: Human
Sample Types: Organoids
Applications: Bioassay

Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis
Authors: MA Scavuzzo, MC Hill, J Chmielowie, D Yang, J Teaw, K Sheng, Y Kong, M Bettini, C Zong, JF Martin, M Borowiak
Nat Commun, 2018-08-22;9(1):3356.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Genetically engineered human cortical spheroid models of tuberous sclerosis
Authors: JD Blair, D Hockemeyer, HS Bateup
Nat. Med., 2018-08-20;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Self-Renewing Trophoblast Organoids Recapitulate the Developmental Program of the Early Human Placenta
Authors: S Haider, G Meinhardt, L Saleh, V Kunihs, M Gamperl, U Kaindl, A Ellinger, TR Burkard, C Fiala, J Pollheimer, S Mendjan, PA Latos, M Knöfler
Stem Cell Reports, 2018-08-02;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Derivation of phenotypically diverse neural culture from hESC by combining adherent and dissociation methods
Authors: Y Liu, A Antonic, X Yang, N Korte, K Lim, AE Michalska, M Dottori, DW Howells
J. Neurosci. Methods, 2018-07-06;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

DEPTOR regulates osteogenic differentiation via inhibiting MEG3-mediated activation of BMP4 signaling and is involved in osteoporosis
Authors: S Chen, L Jia, S Zhang, Y Zheng, Y Zhou
Stem Cell Res Ther, 2018-07-04;9(1):185.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Sequential Application of Discrete Topographical Patterns Enhances Derivation of Functional Mesencephalic Dopaminergic Neurons from Human Induced Pluripotent Stem Cells
Authors: KKB Tan, WWM Lim, C Chai, M Kukumberg, KL Lim, ELK Goh, EKF Yim
Sci Rep, 2018-06-22;8(1):9567.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Random Mutagenesis, Clonal Events, and Embryonic or Somatic Origin Determine the mtDNA Variant Type and Load in Human Pluripotent Stem�Cells
Authors: F Zambelli, J Mertens, D Dziedzicka, J Sterckx, C Markouli, A Keller, P Tropel, L Jung, S Viville, H Van de Vel, M Geens, S Seneca, K Sermon, C Spits
Stem Cell Reports, 2018-06-14;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Human Pluripotent Stem-Cell-Derived Cortical Neurons Integrate Functionally into the Lesioned Adult Murine Visual Cortex in an Area-Specific Way
Authors: I Espuny-Cam, KA Michelsen, D Linaro, A Bilheu, S Acosta-Ver, A Herpoel, M Giugliano, A Gaillard, P Vanderhaeg
Cell Rep, 2018-05-29;23(9):2732-2743.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Decoding the dynamic DNA methylation and hydroxymethylation landscapes in endodermal lineage intermediates during pancreatic differentiation of hESC
Authors: J Li, X Wu, Y Zhou, M Lee, L Guo, W Han, W Mo, WM Cao, D Sun, R Xie, Y Huang
Nucleic Acids Res., 2018-04-06;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Graphene foam as a biocompatible scaffold for culturing human neurons
Authors: GM D'Abaco, C Mattei, B Nasr, EJ Hudson, AJ Alshawaf, G Chana, IP Everall, B Nayagam, M Dottori, E Skafidas
R Soc Open Sci, 2018-03-07;5(3):171364.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Microbiota-Derived Indole Metabolites Promote Human and Murine Intestinal Homeostasis through Regulation of Interleukin-10 Receptor
Authors: EE Alexeev, JM Lanis, DJ Kao, EL Campbell, CJ Kelly, KD Battista, ME Gerich, BR Jenkins, ST Walk, DJ Kominsky, SP Colgan
Am. J. Pathol., 2018-02-16;0(0):.
Species: Human
Sample Types: Organoid
Applications: Bioassay

Cardiotrophic Growth Factor-Driven Induction of Human Muse Cells Into Cardiomyocyte-Like Phenotype
Authors: M Amin, Y Kushida, S Wakao, M Kitada, K Tatsumi, M Dezawa
Cell Transplant, 2018-02-01;27(2):285-298.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Genome-wide analysis of PDX1 target genes in human pancreatic progenitors
Authors: X Wang, M Sterr, I Burtscher, S Chen, A Hieronimus, F Machicao, H Staiger, HU Häring, G Lederer, T Meitinger, FM Cernilogar, G Schotta, M Irmler, J Beckers, M Hrab? de A, M Ray, CVE Wright, M Bakhti, H Lickert
Mol Metab, 2018-01-31;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Enhanced differentiation of human pluripotent stem cells into pancreatic progenitors co-expressing PDX1 and NKX6.1
Authors: B Memon, M Karam, S Al-Khawaga, EM Abdelalim
Stem Cell Res Ther, 2018-01-23;9(1):15.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

BMP/SMAD pathway promotes neurogenesis of midbrain dopaminergic neurons in vivo and in human induced pluripotent and neural stem cells
Authors: VM Jovanovic, A Salti, H Tilleman, K Zega, MM Jukic, H Zou, RH Friedel, N Prakash, S Blaess, F Edenhofer, C Brodski
J. Neurosci., 2018-01-10;0(0):.
Species: Human
Sample Types:

Identification of direct negative crosstalk between the SLIT2 and Bone Morphogenetic Protein-Gremlin signaling pathways
Authors: KE Tumelty, N Higginson-, X Fan, P Bajaj, KM Knowlton, M Shamashkin, AJ Coyle, W Lu, SP Berasi
J. Biol. Chem., 2018-01-09;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Enhanced Utilization of Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids Using Microengineered Chips.
Authors: Michael J Workman, John P Gleeson, Elissa J Troisi, Hannah Q Estrada, S Jordan Kerns, Christopher D Hinojosa, Geraldine A Hamilton, Stephan R Targan, Clive N Svendsen, Robert J Barrett
Cellular and Molecular Gastroenterology and Hepatology, 2017-12-29;0(0):2352-345X.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Directly Converted Human Fibroblasts Mature to Neurons and Show Long-Term Survival in Adult Rodent Hippocampus
Authors: N Avaliani, U Pfisterer, A Heuer, M Parmar, M Kokaia, M Andersson
Stem Cells Int, 2017-11-26;2017(0):5718608.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming
Authors: T Ruetz, U Pfisterer, B Di Stefano, J Ashmore, M Beniazza, TV Tian, DF Kaemena, L Tosti, W Tan, JR Manning, E Chantzoura, DR Ottosson, S Collombet, A Johnsson, E Cohen, K Yusa, S Linnarsson, T Graf, M Parmar, K Kaji
Cell Stem Cell, 2017-11-22;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

TRAIL attenuates RANKL-mediated osteoblastic signalling in vascular cell mono-culture and co-culture models
Authors: E Harper, KD Rochfort, H Forde, C Davenport, D Smith, PM Cummins
PLoS ONE, 2017-11-16;12(11):e0188192.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A right-handed signalling pathway drives heart looping in vertebrates
Authors: OH Ocaña, H Coskun, C Minguillón, P Murawala, EM Tanaka, J Galcerán, R Muñoz-Cháp, MA Nieto
Nature, 2017-09-06;549(7670):86-90.
Species: Zebrafish
Sample Types: Whole Tissue
Applications: Bioassay

Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors
Authors: KF Cogger, A Sinha, F Sarangi, EC McGaugh, D Saunders, C Dorrell, S Mejia-Guer, Y Aghazadeh, JL Rourke, RA Screaton, M Grompe, PR Streeter, AC Powers, M Brissova, T Kislinger, MC Nostro
Nat Commun, 2017-08-24;8(1):331.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Zeb2 is a negative regulator of midbrain dopaminergic axon growth and target innervation
Authors: SV Hegarty, SL Wyatt, L Howard, E Stappers, D Huylebroec, AM Sullivan, GW O'Keeffe
Sci Rep, 2017-08-17;7(1):8568.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A pluripotent stem cell-based model for post-implantation human amniotic sac development
Authors: Y Shao, K Taniguchi, RF Townshend, T Miki, DL Gumucio, J Fu
Nat Commun, 2017-08-08;8(1):208.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

REST suppression mediates neural conversion of adult human fibroblasts via microRNA-dependent and -independent pathways
Authors: J Drouin-Oue, S Lau, PL Brattås, D Rylander O, K Pircs, DA Grassi, LM Collins, R Vuono, A Andersson, G Westergren, C Graff, L Minthon, H Toresson, RA Barker, J Jakobsson, M Parmar
EMBO Mol Med, 2017-08-01;9(8):1117-1131.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling
Authors: JO Múnera, N Sundaram, SA Rankin, D Hill, C Watson, M Mahe, JE Vallance, NF Shroyer, KL Sinagoga, A Zarzoso-La, JR Hudson, JC Howell, P Chatuvedi, JR Spence, JM Shannon, AM Zorn, MA Helmrath, JM Wells
Cell Stem Cell, 2017-06-22;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Establishment of a refined culture method for rat colon organoids
Authors: H Isshiki, Y Arimura, K Nagaishi, K Kawakami, K Onodera, K Yamashita, Y Naishiro, M Fujimiya, K Imai, Y Shinomura
Biochem. Biophys. Res. Commun., 2017-05-27;0(0):.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

Common genetic variation drives molecular heterogeneity in human iPSCs
Authors: H Kilpinen, A Goncalves, A Leha, V Afzal, K Alasoo, S Ashford, S Bala, D Bensaddek, FP Casale, OJ Culley, P Danecek, A Faulconbri, PW Harrison, A Kathuria, D McCarthy, SA McCarthy, R Meleckyte, Y Memari, N Moens, F Soares, A Mann, I Streeter, CA Agu, A Alderton, R Nelson, S Harper, M Patel, A White, SR Patel, L Clarke, R Halai, CM Kirton, A Kolb-Kokoc, P Beales, E Birney, D Danovi, AI Lamond, WH Ouwehand, L Vallier, FM Watt, R Durbin, O Stegle, DJ Gaffney
Nature, 2017-05-10;546(7658):370-375.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Epigenetic and transcriptional modulation of WDR5, a chromatin remodeling protein, in Huntington's disease human induced pluripotent stem cell (hiPSC) model
Authors: S Baronchell, A La Spada, A Ntai, A Barbieri, P Conforti, GS Jotti, S Redaelli, A Bentivegna, P De Blasio, I Biunno
Mol. Cell. Neurosci., 2017-05-02;82(0):46-57.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Bone morphogenetic protein signaling mediated by ALK-2 and DLX2 regulates apoptosis in glioma-initiating cells
Authors: E Raja, A Komuro, R Tanabe, S Sakai, Y Ino, N Saito, T Todo, M Morikawa, H Aburatani, D Koinuma, C Iwata, K Miyazono
Oncogene, 2017-05-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A hypomorphic PIGA gene mutation causes severe defects in neuron development and susceptibility to complement-mediated toxicity in a human iPSC model
Authors: X Yuan, Z Li, AC Baines, E Gavriilaki, Z Ye, Z Wen, EM Braunstein, LG Biesecker, L Cheng, X Dong, RA Brodsky
PLoS ONE, 2017-04-25;12(4):e0174074.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Melanoma-Derived iPCCs Show Differential Tumorigenicity and Therapy Response
Authors: M Bernhardt, D Novak, Y Assenov, E Orouji, N Knappe, K Weina, M Reith, L Larribere, C Gebhardt, C Plass, V Umansky, J Utikal
Stem Cell Reports, 2017-04-06;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Differentiation of oligodendrocyte progenitor cells from dissociated monolayer and feeder-free cultured pluripotent stem cells
Authors: T Yamashita, Y Miyamoto, Y Bando, T Ono, S Kobayashi, A Doi, T Araki, Y Kato, T Shirakawa, Y Suzuki, J Yamauchi, S Yoshida, N Sato
PLoS ONE, 2017-02-13;12(2):e0171947.
Species: Primate
Sample Types: Whole Cells
Applications: Bioassay

Species-specific developmental timing is maintained by pluripotent stem cells ex utero
Authors: C Barry, MT Schmitz, P Jiang, MP Schwartz, BM Duffin, S Swanson, R Bacher, JM Bolin, AL Elwell, BE McIntosh, R Stewart, JA Thomson
Dev. Biol., 2017-02-06;423(2):101-110.
Species: Human
Sample Types: Whole Cells
Applications: Differentiation, Differentiation

Wnt/?-catenin promotes gastric fundus specification in mice and humans
Authors: KW McCracken, E Aihara, B Martin, CM Crawford, T Broda, J Treguier, X Zhang, JM Shannon, MH Montrose, JM Wells
Nature, 2017-01-04;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Reductive carboxylation is a major metabolic pathway in the retinal pigment epithelium
Proc. Natl. Acad. Sci. U.S.A., 2016-12-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

BMP4/Id2 signaling pathway is a novel therapeutic target for late outgrowth endothelial progenitor cell-mediated endothelial injury repair
Authors: Jun Tao
Int. J. Cardiol., 2016-11-09;228(0):796-804.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Remyelination Is Correlated with Regulatory T Cell Induction Following Human Embryoid Body-Derived Neural Precursor Cell Transplantation in a Viral Model of Multiple Sclerosis
Authors: Warren C Plaisted
PLoS ONE, 2016-06-16;11(6):e0157620.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Growth hormone is permissive for neoplastic colon growth
Proc Natl Acad Sci USA, 2016-05-25;0(0):.
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay

Altered neuronal network and rescue in a human MECP2 duplication model
Mol. Psychiatry, 2015-09-08;21(2):178-88.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

DNA methylation directs functional maturation of pancreatic beta cells.
Authors: Dhawan S, Tschen S, Zeng C, Guo T, Hebrok M, Matveyenko A, Bhushan A
J Clin Invest, 2015-06-22;125(7):2851-60.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors.
Authors: Cebola I, Rodriguez-Segui S, Cho C, Bessa J, Rovira M, Luengo M, Chhatriwala M, Berry A, Ponsa-Cobas J, Maestro M, Jennings R, Pasquali L, Moran I, Castro N, Hanley N, Gomez-Skarmeta J, Vallier L, Ferrer J
Nat Cell Biol, 2015-04-27;17(5):615-26.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

In vitro generation of human pluripotent stem cell derived lung organoids.
Authors: Dye, Briana R, Hill, David R, Ferguson, Michael, Tsai, Yu-Hwai, Nagy, Melinda, Dyal, Rachel, Wells, James M, Mayhew, Christop, Nattiv, Roy, Klein, Ophir D, White, Eric S, Deutsch, Gail H, Spence, Jason R
Elife, 2015-03-24;4(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Analysing human neural stem cell ontogeny by consecutive isolation of Notch active neural progenitors.
Authors: Edri, Reuven, Yaffe, Yakey, Ziller, Michael, Mutukula, Naresh, Volkman, Rotem, David, Eyal, Jacob-Hirsch, Jasmine, Malcov, Hagar, Levy, Carmit, Rechavi, Gideon, Gat-Viks, Irit, Meissner, Alexande, Elkabetz, Yechiel
Nat Commun, 2015-03-23;6(0):6500.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Resveratrol ameliorates the maturation process of beta-cell-like cells obtained from an optimized differentiation protocol of human embryonic stem cells.
Authors: Pezzolla D, Lopez-Beas J, Lachaud C, Dominguez-Rodriguez A, Smani T, Hmadcha A, Soria B
PLoS ONE, 2015-03-16;10(3):e0119904.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The in vitro generation of lung and airway progenitor cells from human pluripotent stem cells.
Authors: Huang S, Green M, de Carvalho A, Mumau M, Chen Y, D'Souza S, Snoeck H
Nat Protoc, 2015-02-05;10(3):413-25.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A dynamic Shh expression pattern, regulated by SHH and BMP signaling, coordinates fusion of primordia in the amniote face.
Authors: Hu D, Young N, Li X, Xu Y, Hallgrimsson B, Marcucio R
Development, 2015-02-01;142(3):567-74.
Species: Chicken
Sample Types: Whole Organism
Applications: In Vivo

Early intervention for spinal cord injury with human induced pluripotent stem cells oligodendrocyte progenitors.
Authors: All A, Gharibani P, Gupta S, Bazley F, Pashai N, Chou B, Shah S, Resar L, Cheng L, Gearhart J, Kerr C
PLoS ONE, 2015-01-30;10(1):e0116933.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Selective lentiviral gene delivery to CD133-expressing human glioblastoma stem cells.
Authors: Bayin, N Sumru, Modrek, Aram S, Dietrich, August, Lebowitz, Jonathan, Abel, Tobias, Song, Hae-Ri, Schober, Markus, Zagzag, David, Buchholz, Christia, Chao, Moses V, Placantonakis, Dimitris
PLoS ONE, 2014-12-26;9(12):e116114.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

SMAD4 exerts a tumor-promoting role in hepatocellular carcinoma.
Authors: Hernanda P, Chen K, Das A, Sideras K, Wang W, Li J, Cao W, Bots S, Kodach L, de Man R, Ijzermans J, Janssen H, Stubbs A, Sprengers D, Bruno M, Metselaar H, ten Hagen T, Kwekkeboom J, Peppelenbosch M, Pan Q
Oncogene, 2014-12-22;34(39):5055-68.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Persistence and toxin production by Clostridium difficile within human intestinal organoids result in disruption of epithelial paracellular barrier function.
Authors: Leslie J, Huang S, Opp J, Nagy M, Kobayashi M, Young V, Spence J
Infect Immun, 2014-10-13;83(1):138-45.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Highly efficient generation of induced neurons from human fibroblasts that survive transplantation into the adult rat brain.
Authors: Pereira, Maria, Pfisterer, Ulrich, Rylander, Daniella, Torper, Olof, Lau, Shong, Lundblad, Martin, Grealish, Shane, Parmar, Malin
Sci Rep, 2014-09-11;4(0):6330.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Real-time discrimination between proliferation and neuronal and astroglial differentiation of human neural stem cells.
Authors: Lee, Rimi, Kim, Il-Sun, Han, Nalae, Yun, Seokhwan, Park, Kook In, Yoo, Kyung-Hw
Sci Rep, 2014-09-10;4(0):6319.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Dual small-molecule targeting of SMAD signaling stimulates human induced pluripotent stem cells toward neural lineages.
Authors: Wattanapanitch M, Klincumhom N, Potirat P, Amornpisutt R, Lorthongpanich C, U-pratya Y, Laowtammathron C, Kheolamai P, Poungvarin N, Issaragrisil S
PLoS ONE, 2014-09-10;9(9):e106952.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Optimal effector functions in human natural killer cells rely upon autocrine bone morphogenetic protein signaling.
Authors: Robson N, Hidalgo L, McAlpine T, Wei H, Martinez V, Entrena A, Melen G, MacDonald A, Phythian-Adams A, Sacedon R, Maraskovsky E, Cebon J, Ramirez M, Vicente A, Varas A
Cancer Res, 2014-07-18;74(18):5019-31.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A multiplex high-throughput gene expression assay to simultaneously detect disease and functional markers in induced pluripotent stem cell-derived retinal pigment epithelium.
Authors: Ferrer M, Corneo B, Davis J, Wan Q, Miyagishima K, King R, Maminishkis A, Marugan J, Sharma R, Shure M, Temple S, Miller S, Bharti K
Stem Cells Transl Med, 2014-05-29;3(8):911-22.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Polycomb group protein expression during differentiation of human embryonic stem cells into pancreatic lineage in vitro.
Authors: Pethe, Prasad, Nagvenkar, Punam, Bhartiya, Deepa
BMC Cell Biol, 2014-05-24;15(0):18.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A gradient of Bmp7 specifies the tonotopic axis in the developing inner ear.
Authors: Mann Z, Thiede B, Chang W, Shin J, May-Simera H, Lovett M, Corwin J, Kelley M
Nat Commun, 2014-05-20;5(0):3839.
Species: Chicken
Sample Types: Whole Cells
Applications: Bioassay

Retinoic acid signalling regulates the development of tonotopically patterned hair cells in the chicken cochlea.
Authors: Thiede B, Mann Z, Chang W, Ku Y, Son Y, Lovett M, Kelley M, Corwin J
Nat Commun, 2014-05-20;5(0):3840.
Species: Chicken
Sample Types: Whole Tissue
Applications: Bioassay

The phosphorylation status of Ascl1 is a key determinant of neuronal differentiation and maturation in vivo and in vitro.
Authors: Ali F, Cheng K, Kirwan P, Metcalfe S, Livesey F, Barker R, Philpott A
Development, 2014-05-12;141(11):2216-24.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CEP290 gene transfer rescues Leber congenital amaurosis cellular phenotype.
Authors: Burnight E, Wiley L, Drack A, Braun T, Anfinson K, Kaalberg E, Halder J, Affatigato L, Mullins R, Stone E, Tucker B
Gene Ther, 2014-05-08;21(7):662-72.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Primary cilia in stem cells and neural progenitors are regulated by neutral sphingomyelinase 2 and ceramide.
Authors: He Q, Wang G, Wakade S, Dasgupta S, Dinkins M, Kong J, Spassieva S, Bieberich E
Mol Biol Cell, 2014-04-02;25(11):1715-29.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Defined human pluripotent stem cell culture enables highly efficient neuroepithelium derivation without small molecule inhibitors.
Authors: Lippmann E, Estevez-Silva M, Ashton R
Stem Cells, 2014-04-01;32(4):1032-42.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Endodermal differentiation of human pluripotent stem cells to insulin-producing cells in 3D culture.
Authors: Takeuchi, Hiroki, Nakatsuji, Norio, Suemori, Hirofumi
Sci Rep, 2014-03-27;4(0):4488.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Neuroprotection by rAAV-mediated gene transfer of bone morphogenic protein 7.
Authors: Heinonen A, Rahman M, Dogbevia G, Jakobi H, Wolfl S, Sprengel R, Schwaninger M
BMC Neurosci, 2014-03-11;15(0):38.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Inner ear hair cell-like cells from human embryonic stem cells.
Authors: Ronaghi, Mohammad, Nasr, Marjan, Ealy, Megan, Durruthy-Durruthy, Robert, Waldhaus, Joerg, Diaz, Giovanni, Joubert, Lydia-Ma, Oshima, Kazuo, Heller, Stefan
Stem Cells Dev, 2014-03-10;23(11):1275-84.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Prospectively isolated NGN3-expressing progenitors from human embryonic stem cells give rise to pancreatic endocrine cells.
Authors: Cai, Qing, Bonfanti, Paola, Sambathkumar, Rangaraj, Vanuytsel, Kim, Vanhove, Jolien, Gysemans, Conny, Debiec-Rychter, Maria, Raitano, Susanna, Heimberg, Harry, Ordovas, Laura, Verfaillie, Catherin
Stem Cells Transl Med, 2014-02-03;3(4):489-99.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Influence of in vitro and in vivo oxygen modulation on beta cell differentiation from human embryonic stem cells.
Authors: Cechin S, Alvarez-Cubela S, Giraldo J, Molano R, Villate S, Ricordi C, Pileggi A, Inverardi L, Fraker C, Dominguez-Bendala J
Stem Cells Transl Med, 2013-12-27;3(3):277-89.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Rapid and efficient differentiation of human pluripotent stem cells into intermediate mesoderm that forms tubules expressing kidney proximal tubular markers.
Authors: Lam A, Freedman B, Morizane R, Lerou P, Valerius M, Bonventre J
J Am Soc Nephrol, 2013-12-19;25(6):1211-25.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A synthetic peptide-acrylate surface for production of insulin-producing cells from human embryonic stem cells.
Authors: Lin P, Hung S, Yang Y, Liao L, Hsieh Y, Yen H, Lu H, Lee M, Chu I, Hwang S
Stem Cells Dev, 2013-11-16;23(4):372-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Recessive mutations in a distal PTF1A enhancer cause isolated pancreatic agenesis.
Authors: Weedon M, Cebola I, Patch A, Flanagan S, De Franco E, Caswell R, Rodriguez-Segui S, Shaw-Smith C, Cho C, Lango Allen H, Houghton J, Roth C, Chen R, Hussain K, Marsh P, Vallier L, Murray A, Ellard S, Ferrer J, Hattersley A
Nat Genet, 2013-11-10;46(1):61-4.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Inhibition of bone morphogenic protein 4 restores endothelial function in db/db diabetic mice.
Authors: Zhang Y, Liu J, Tian X, Wong W, Chen Y, Wang L, Luo J, Cheang W, Lau C, Kwan K, Wang N, Yao X, Huang Y
Arterioscler Thromb Vasc Biol, 2013-11-07;34(1):152-9.
Species: Mouse
Sample Types: Whole Organism, Whole Tissue
Applications: Bioassay, In Vivo

Enrichment of human embryonic stem cell-derived NKX6.1-expressing pancreatic progenitor cells accelerates the maturation of insulin-secreting cells in vivo.
Authors: Rezania A, Bruin J, Xu J, Narayan K, Fox J, O'Neil J, Kieffer T
Stem Cells, 2013-11-01;31(11):2432-42.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Bone morphogenetic protein 2 signaling negatively modulates lymphatic development in vertebrate embryos.
Authors: Dunworth, William, Cardona-Costa, Jose, Bozkulak, Esra Cag, Kim, Jun-Dae, Meadows, Stryder, Fischer, Johanna, Wang, Yeqi, Cleaver, Ondine, Qyang, Yibing, Ober, Elke A, Jin, Suk-Won
Circ Res, 2013-10-11;114(1):56-66.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Generation of multipotent foregut stem cells from human pluripotent stem cells.
Authors: Hannan, Nicholas, Fordham, Robert P, Syed, Yasir A, Moignard, Victoria, Berry, Andrew, Bautista, Ruben, Hanley, Neil A, Jensen, Kim B, Vallier, Ludovic
Stem Cell Reports, 2013-10-10;1(4):293-306.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Bone morphogenetic protein-2/-4 upregulation promoted by endothelial cells in coculture enhances mouse embryoid body differentiation.
Authors: Talavera-Adame, Dodanim, Gupta, Ankur, Kurtovic, Silvia, Chaiboonma, Kira L, Arumugaswami, Vaithili, Dafoe, Donald C
Stem Cells Dev, 2013-09-24;22(24):3252-60.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Patient-specific iPSC-derived photoreceptor precursor cells as a means to investigate retinitis pigmentosa.
Authors: Tucker, Budd A, Mullins, Robert F, Streb, Luan M, Anfinson, Kristin, Eyestone, Mari E, Kaalberg, Emily, Riker, Megan J, Drack, Arlene V, Braun, Terry A, Stone, Edwin M
Elife, 2013-08-27;2(0):e00824.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Translating dosage compensation to trisomy 21.
Authors: Jiang J, Jing Y, Cost G, Chiang J, Kolpa H, Cotton A, Carone D, Carone B, Shivak D, Guschin D, Pearl J, Rebar E, Byron M, Gregory P, Brown C, Urnov F, Hall L, Lawrence J
Nature, 2013-07-17;500(7462):296-300.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells.
Authors: Maroof A, Keros S, Tyson J, Ying S, Ganat Y, Merkle F, Liu B, Goulburn A, Stanley E, Elefanty A, Widmer H, Eggan K, Goldstein P, Anderson S, Studer L
Cell Stem Cell, 2013-05-02;12(5):559-72.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Rapid and efficient directed differentiation of human pluripotent stem cells into retinal pigmented epithelium.
Authors: Buchholz, David E, Pennington, Britney, Croze, Roxanne, Hinman, Cassidy, Coffey, Peter J, Clegg, Dennis O
Stem Cells Transl Med, 2013-04-18;2(5):384-93.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Activation of the type I interferon pathway is enhanced in response to human neuronal differentiation.
Authors: Farmer, Jocelyn, Altschaefl, Kate M, O'Shea, K Sue, Miller, David J
PLoS ONE, 2013-03-07;8(3):e58813.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Use of a synthetic xeno-free culture substrate for induced pluripotent stem cell induction and retinal differentiation.
Authors: Tucker B, Anfinson K, Mullins R, Stone E, Young M
Stem Cells Transl Med, 2012-12-27;2(1):16-24.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions.
Authors: Brafman D, Phung C, Kumar N, Willert K
Cell Death Differ, 2012-11-16;20(3):369-81.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Interplay between electrical activity and bone morphogenetic protein signaling regulates spinal neuron differentiation.
Authors: Swapna, Immani, Borodinsky, Laura N
Proc Natl Acad Sci U S A, 2012-09-18;109(40):16336-41.
Species: Xenopus
Sample Types: Whole Tissue
Applications: Bioassay

Cited2 gene controls pluripotency and cardiomyocyte differentiation of murine embryonic stem cells through Oct4 gene.
Authors: Li Q, Ramirez-Bergeron D, Dunwoodie S, Yang Y
J Biol Chem, 2012-07-03;287(34):29088-100.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Downregulation of hemojuvelin prevents inhibitory effects of bone morphogenetic proteins on iron metabolism in hepatocellular carcinoma.
Authors: Maegdefrau U, Arndt S, Kivorski G, Hellerbrand C, Bosserhoff AK
Lab. Invest., 2011-08-22;91(11):1615-23.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro.
Authors: Spence JR, Mayhew CN, Rankin SA
Nature, 2010-12-12;470(7332):105-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A defined glycosaminoglycan-binding substratum for human pluripotent stem cells.
Authors: Klim JR, Li L, Wrighton PJ
Nat. Methods, 2010-11-14;7(12):989-94.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay