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Recombinant Mouse IFN-gamma Protein

Catalog #: 485-MI
445 Citations 13 Reviews Datasheet / COA / SDS

Carrier Free

Catalog # Availability Size / Price Qty
485-MI-100/CF

With Carrier

Catalog # Availability Size / Price Qty
485-MI-100
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Recombinant Mouse IFN-gamma Protein Bioactivity
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Product Details
Citations (445)
FAQs
Reviews (13)
Summary Product Datasheets Carrier Free Data Images Reconstitution Calculator Background Related Research Areas

Recombinant Mouse IFN-gamma Protein Summary

Product Specifications

Purity
>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
Activity
Measured in an anti-viral assay using L‑929 mouse fibroblast cells infected with encephalomyocarditis (EMC) virus. Vogel, S.N. et al. (1982) Infect. Immunol. 38:681. The ED50 for this effect is 0.3-0.9 ng/mL.
Source
E. coli-derived mouse IFN-gamma protein
His23-Cys155, with an N-terminal Met
Accession #
NP_032363
N-terminal Sequence
Analysis
Met
Predicted Molecular Mass
15.6 kDa
SDS-PAGE
11-12 kDa, reducing conditions

Product Datasheets

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485-MI (with carrier)

Product Datasheet
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SDS

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485-MI/CF (carrier free)

Product Datasheet
COA
SDS

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

485-MI

Formulation Lyophilized from a 0.2 μm filtered solution in Sodium Succinate, Mannitol,Tween® 80 and TCEP with BSA as a carrier protein.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

485-MI/CF

Formulation Lyophilized from a 0.2 μm filtered solution in Sodium Succinate, Mannitol,Tween® 80 and TCEP with Trehalose.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Scientific Data

Bioactivity Recombinant Mouse IFN-gamma Protein Bioactivity View Larger

Recombinant Mouse IFN-gamma (Catalog # 485-ML) demonstrates anti-viral activity in L-929 mouse fibroblast cells infected with encephalomyocarditis (EMC) virus. The ED50 for this effect is 0.3-0.9 ng/mL.

SDS-PAGE Recombinant Mouse IFN-gamma Protein SDS-PAGE View Larger

1 μg/lane of Recombinant Mouse IFN-gamma was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 11-12 kDa.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: IFN-gamma

Interferon-gamma (IFN-gamma ), also known as type II or immune interferon, exerts a wide range of immunoregulatory activities and is considered to be the prototype proinflammatory cytokine (1, 2). Mature mouse IFN-gamma exists as a noncovalently linked homodimer of 20-25 kDa variably glycosylated subunits (3). It shares 86% amino acid sequence identity with rat IFN-gamma and 38%-44% with bovine, canine, cotton rat, equine, feline, human, porcine, and rhesus IFN-gamma. IFN-gamma dimers bind to IFN‑ gamma RI (alpha subunits) which then interact with IFN-gamma RII (beta subunits) to form the functional receptor complex of two alpha and two beta subunits. Inclusion of IFN-gamma RII increases the binding affinity for ligand and the efficiency of signal transduction (4, 5). IFN-gamma is produced by a variety of immune cells under inflammatory conditions, notably by T cells and NK cells (6). It plays a key role in host defense by promoting the development and activation of Th1 cells, chemoattraction and activation of monocytes and macrophages, up-regulation of antigen presentation molecules, and immunoglobulin class switching in B cells. It also exhibits antiviral, antiproliferative, and apoptotic effects (6, 7). In addition, IFN-gamma functions as an anti-inflammatory mediator by promoting the development of regulatory T cells and inhibiting Th17 cell differentiation (8, 9). The pleiotropic effects of IFN-gamma contribute to the development of multiple aspects of atherosclerosis (7).

References
  1. Billiau, A. and P. Matthys (2009) Cytokine Growth Factor Rev. 20:97.
  2. Pestka, S. et al. (2004) Immunol. Rev. 202:8.
  3. Gray, P.W. and D.V. Goeddel (1983) Proc. Natl. Acad. Sci. 80:5842.
  4. Marsters, S.A. et al. (1995) Proc. Natl. Acad. Sci. 92:5401.
  5. Krause, C.D. et al. (2000) J. Biol. Chem. 275:22995.
  6. Schroder, K. et al. (2004) J. Leukoc. Biol. 75:163.
  7. McLaren, J.E. and D.P. Ramji (2009) Cytokine Growth Factor Rev. 20:125.
  8. Muhl, H. and J. Pfeilschifter (2003) Int. Immunopharmacol. 3:1247.
  9. Kelchtermans, H. et al. (2008) Trends Immunol. 29:479.
Long Name
Interferon gamma
Entrez Gene IDs
3458 (Human); 15978 (Mouse); 25712 (Rat); 396991 (Porcine); 281237 (Bovine); 403801 (Canine); 493965 (Feline)
Alternate Names
IFG; IFI; IFNG; IFNgamma; IFN-gamma; Immune interferon; interferon gamma; interferon, gamma

Citations for Recombinant Mouse IFN-gamma Protein

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

445 Citations: Showing 1 - 10
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  1. Acquired Immunostimulatory Phenotype of Migratory CD103+ Dendritic Cells Promotes Alloimmunity Following Corneal Transplantation
    Authors: Blanco, T;Nakagawa, H;Musayeva, A;Krauthammer, M;Singh, RB;Narimatsu, A;Ge, H;Shoushtari, SI;Dana, R;
    JCI insight
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  2. Defining cell type-specific immune responses in a mouse model of allergic contact dermatitis by single-cell transcriptomics
    Authors: Liu, Y;Yin, M;Mao, X;Wu, S;Wei, S;Heng, S;Yang, Y;Huang, J;Guo, Z;Li, C;Ji, C;Hu, L;Liu, W;Zhang, LJ;
    eLife
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  3. Fatty acid derivatization and cyclization of the immunomodulatory peptide RP-182 targeting CD206high macrophages improves anti-tumor activity
    Authors: Singh, SS;Calvo, R;Kumari, A;Sable, RV;Fang, Y;Tao, D;Hu, X;Castle, SG;Nahar, S;Li, D;Major, E;Sanchez, TW;Kato, R;Xu, X;Zhou, J;Liu, L;LeClair, CA;Simeonov, A;Baljinnyam, B;Henderson, MJ;Marugan, J;Rudloff, U;
    Molecular cancer therapeutics
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  4. Astrocytes and the tumor microenvironment inflammatory state dictate the killing of glioblastoma cells by Smac mimetic compounds
    Authors: Malone, K;Dugas, M;Earl, N;Alain, T;LaCasse, EC;Beug, ST;
    Cell death & disease
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  5. The interferon ? pathway enhances pluripotency and X-chromosome reactivation in iPSC reprogramming
    Authors: Barrero, M;Lazarenkov, A;Blanco, E;Palma, LG;López-Rubio, AV;Bauer, M;Bigas, A;Di Croce, L;Sardina, JL;Payer, B;
    Science advances
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  6. Alterations of ceramide synthesis induce PD-L1 internalization and signaling to regulate tumor metastasis and immunotherapy response
    Authors: Wofford, W;Kim, J;Kim, D;Janneh, AH;Lee, HG;Atilgan, FC;Oleinik, N;Kassir, MF;Saatci, O;Chakraborty, P;Tokat, UM;Gencer, S;Howley, B;Howe, P;Mehrotra, S;Sahin, O;Ogretmen, B;
    Cell reports
    Species: Human, Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  7. ASO-mediated knockdown of GPNMB in mutant- GRN and Grn -deficient peripheral myeloid cells disrupts lysosomal function and immune responses
    Authors: Wallings, RL;Gillett, DA;Staley, HA;Mahn, S;Mark, J;Neighbarger, N;Kordasiewicz, H;Hirst, WD;Tansey, MG;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  8. ATM inhibition enhance immunotherapy by activating STING signaling and augmenting MHC Class I
    Authors: Li, C;Wang, B;Tu, J;Liu, C;Wang, Y;Chen, J;Huang, Y;Liu, B;Yuan, X;
    Cell death & disease
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  9. The catheterized bladder environment induces dysregulation of macrophage polarization exacerbating bacterial UTI
    Authors: Marrufo, AM;Molina, JJ;Gager, C;Andersen, MJ;LaBella, AA;Lucas, ER;Wongso, E;Urmi, T;Arias-Parbul, K;Webster, R;Stuckey, PV;Kohler, KN;Donahue, D;Ploplis, VA;Flick, MJ;Castellino, FJ;Santiago-Tirado, FH;Flores-Mireles, AL;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  10. Mechanisms underlying TRPV4-mediated regulation of miR-146a expression
    Authors: Dutta, B;Mahanty, M;Kesavalu, L;Rahaman, SO;
    bioRxiv : the preprint server for biology
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  11. PAD4 controls tumor immunity via restraining the MHC class II machinery in macrophages
    Authors: Pitter, MR;Kryczek, I;Zhang, H;Nagarsheth, N;Xia, H;Wu, Z;Tian, Y;Okla, K;Liao, P;Wang, W;Zhou, J;Li, G;Lin, H;Vatan, L;Grove, S;Wei, S;Li, Y;Zou, W;
    Cell reports
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  12. Thrombospondin-1, BIM and CFH polymorphisms and response to anti-VEGF treatment in neovascular age- related macular degeneration patients
    Authors: Sorenson, CM;Gurel, Z;Song, YS;Peterson, KD;Blodi, BA;Sheibani, N;
    PloS one
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  13. Neutral ceramidase regulates breast cancer progression by metabolic programming of TREM2-associated macrophages
    Authors: Sun, R;Lei, C;Xu, Z;Gu, X;Huang, L;Chen, L;Tan, Y;Peng, M;Yaddanapudi, K;Siskind, L;Kong, M;Mitchell, R;Yan, J;Deng, Z;
    Nature communications
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  14. Loss of MTX2 causes mitochondrial dysfunction, podocyte injury, nephrotic proteinuria and glomerulopathy in mice and patients
    Authors: Li, T;Bao, Y;Xia, Y;Meng, H;Zhou, C;Huang, L;Wang, X;Lai, EY;Jiang, P;Mao, J;
    International journal of biological sciences
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  15. Downregulation of nutrition sensor GCN2 in macrophages contributes to poor wound healing in diabetes
    Authors: Hou, Y;Wei, D;Zhang, Z;Lei, T;Li, S;Bao, J;Guo, H;Tan, L;Xie, X;Zhuang, Y;Lu, Z;Zhao, Y;
    Cell reports
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  16. A novel mucosal bivalent vaccine of EV-A71/EV-D68 adjuvanted with polysaccharides from Ganoderma lucidum protects mice against EV-A71 and EV-D68 lethal challenge
    Authors: Lin, YL;Cheng, PY;Chin, CL;Chuang, KT;Lin, JY;Chang, N;Pan, CK;Lin, CS;Pan, SC;Chiang, BL;
    Journal of biomedical science
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  17. Bacterial-induced or passively administered interferon gamma conditions the lung for early control of SARS-CoV-2
    Authors: Hilligan, KL;Namasivayam, S;Clancy, CS;Baker, PJ;Old, SI;Peluf, V;Amaral, EP;Oland, SD;O'Mard, D;Laux, J;Cohen, M;Garza, NL;Lafont, BAP;Johnson, RF;Feng, CG;Jankovic, D;Lamiable, O;Mayer-Barber, KD;Sher, A;
    Nature communications
    Species: Mouse
    Sample Types: In Vivo
    Applications: In vivo assay
  18. Targeting the lipid kinase PIKfyve upregulates surface expression of MHC class I to augment cancer immunotherapy
    Authors: Bao, Y;Qiao, Y;Choi, JE;Zhang, Y;Mannan, R;Cheng, C;He, T;Zheng, Y;Yu, J;Gondal, M;Cruz, G;Grove, S;Cao, X;Su, F;Wang, R;Chang, Y;Kryczek, I;Cieslik, M;Green, MD;Zou, W;Chinnaiyan, AM;
    Proceedings of the National Academy of Sciences of the United States of America
    Species: Xenograft
    Sample Types: Whole Cells
    Applications: ICC
  19. Holothurian triterpene glycoside cucumarioside A2-2 induces macrophages activation and polarization in cancer immunotherapy
    Authors: Chuang, WH;Pislyagin, E;Lin, LY;Menchinskaya, E;Chernikov, O;Kozhemyako, V;Gorpenchenko, T;Manzhulo, I;Chaikina, E;Agafonova, I;Silchenko, A;Avilov, S;Stonik, V;Tzou, SC;Aminin, D;Wang, YM;
    Cancer cell international
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  20. Lactobacillus from the Altered Schaedler Flora maintain IFN? homeostasis to promote behavioral stress resilience
    Authors: Merchak, AR;Wachamo, S;Brown, LC;Thakur, A;Moreau, B;Brown, RM;Rivet-Noor, C;Raghavan, T;Gaultier, A;
    Brain, behavior, and immunity
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  21. Excretory/secretory products from Trichinella spiralis adult worms ameliorate myocardial infarction by inducing M2 macrophage polarization in a mouse model
    Authors: Wu, L;Yin, W;Wen, J;Wang, S;Li, H;Wang, X;Zhang, W;Duan, S;Zhu, Q;Gao, E;Wu, S;Zhan, B;Zhou, R;Yang, X;
    Parasites & vectors
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  22. Polarized microtubule remodeling transforms the morphology of reactive microglia and drives cytokine release
    Authors: Adrian, M;Weber, M;Tsai, MC;Glock, C;Kahn, OI;Phu, L;Cheung, TK;Meilandt, WJ;Rose, CM;Hoogenraad, CC;
    Nature communications
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  23. The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity
    Authors: Baumgartner, CK;Ebrahimi-Nik, H;Iracheta-Vellve, A;Hamel, KM;Olander, KE;Davis, TGR;McGuire, KA;Halvorsen, GT;Avila, OI;Patel, CH;Kim, SY;Kammula, AV;Muscato, AJ;Halliwill, K;Geda, P;Klinge, KL;Xiong, Z;Duggan, R;Mu, L;Yeary, MD;Patti, JC;Balon, TM;Mathew, R;Backus, C;Kennedy, DE;Chen, A;Longenecker, K;Klahn, JT;Hrusch, CL;Krishnan, N;Hutchins, CW;Dunning, JP;Bulic, M;Tiwari, P;Colvin, KJ;Chuong, CL;Kohnle, IC;Rees, MG;Boghossian, A;Ronan, M;Roth, JA;Wu, MJ;Suermondt, JSMT;Knudsen, NH;Cheruiyot, CK;Sen, DR;Griffin, GK;Golub, TR;El-Bardeesy, N;Decker, JH;Yang, Y;Guffroy, M;Fossey, S;Trusk, P;Sun, IM;Liu, Y;Qiu, W;Sun, Q;Paddock, MN;Farney, EP;Matulenko, MA;Beauregard, C;Frost, JM;Yates, KB;Kym, PR;Manguso, RT;
    Nature
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  24. Response Profiles of BV2 Microglia to IFN-? and LPS Co-Stimulation and Priming
    Authors: Pan, ML;Ahmad Puzi, NN;Ooi, YY;Ramasamy, R;Vidyadaran, S;
    Biomedicines
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  25. Clonal MDS/AML cells with enhanced TWIST1 expression reprogram the differentiation of bone marrow MSCs
    Authors: Li, H;Wang, Y;Yang, F;Feng, S;Chang, K;Yu, X;Guan, F;Li, X;
    Redox biology
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  26. Glutaredoxin attenuates glutathione levels via deglutathionylation of Otub1 and subsequent destabilization of system xC
    Authors: Aboushousha, R;van der Velden, J;Hamilton, N;Peng, Z;MacPherson, M;Erickson, C;White, S;Wouters, EFM;Reynaert, NL;Seward, DJ;Li, J;Janssen-Heininger, YMW;
    Science advances
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  27. TPL2 kinase activity regulates microglial inflammatory responses and promotes neurodegeneration in tauopathy mice
    Authors: Wang, Y;Wu, T;Tsai, MC;Rezzonico, MG;Abdel-Haleem, AM;Xie, L;Gandham, VD;Ngu, H;Stark, K;Glock, C;Xu, D;Foreman, O;Friedman, BA;Sheng, M;Hanson, JE;
    eLife
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  28. Combined PD-L1/TGF? blockade allows expansion and differentiation of stem cell-like CD8 T cells in immune excluded tumors
    Authors: Castiglioni, A;Yang, Y;Williams, K;Gogineni, A;Lane, RS;Wang, AW;Shyer, JA;Zhang, Z;Mittman, S;Gutierrez, A;Astarita, JL;Thai, M;Hung, J;Yang, YA;Pourmohamad, T;Himmels, P;De Simone, M;Elstrott, J;Capietto, AH;Cubas, R;Modrusan, Z;Sandoval, W;Ziai, J;Gould, SE;Fu, W;Wang, Y;Koerber, JT;Sanjabi, S;Mellman, I;Turley, SJ;Müller, S;
    Nature communications
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  29. Tryptophan metabolism promotes immune evasion in human pancreatic beta cells
    Authors: Rachdi, L;Zhou, Z;Berthault, C;Lourenço, C;Fouque, A;Domet, T;Armanet, M;You, S;Peakman, M;Mallone, R;Scharfmann, R;
    EBioMedicine
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  30. Reactive nitrogen species inhibit branched chain alpha-ketoacid dehydrogenase complex and impact muscle cell metabolism
    Authors: Arp, NL;Seim, G;Josephson, J;Fan, J;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  31. Distribution of Signal Peptides in Microvesicles from Activated Macrophage Cells
    Authors: Ono, K;Sato, J;Suzuki, H;Sawada, M;
    International journal of molecular sciences
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  32. Pharmacological blockade of cannabinoid receptor 2 signaling does not affect LPS/IFN-gamma -induced microglial activation
    Authors: Olabiyi, BF;Schmoele, AC;Beins, EC;Zimmer, A;
    Scientific reports
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Stimulation
  33. B-cell-specific checkpoint molecules that regulate anti-tumour immunity
    Authors: Bod, L;Kye, YC;Shi, J;Torlai Triglia, E;Schnell, A;Fessler, J;Ostrowski, SM;Von-Franque, MY;Kuchroo, JR;Barilla, RM;Zaghouani, S;Christian, E;Delorey, TM;Mohib, K;Xiao, S;Slingerland, N;Giuliano, CJ;Ashenberg, O;Li, Z;Rothstein, DM;Fisher, DE;Rozenblatt-Rosen, O;Sharpe, AH;Quintana, FJ;Apetoh, L;Regev, A;Kuchroo, VK;
    Nature
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  34. Effects of sevoflurane on lung epithelial permeability in experimental models of acute respiratory distress syndrome
    Authors: Zhai, R;Lenga Ma Bonda, W;Leclaire, C;Saint-Béat, C;Theilliere, C;Belville, C;Coupet, R;Blondonnet, R;Bouvier, D;Blanchon, L;Sapin, V;Jabaudon, M;
    Journal of translational medicine
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  35. Leishmania major drives host phagocyte death and cell-to-cell transfer depending on intracellular pathogen proliferation rate
    Authors: Baars, I;Jaedtka, M;Dewitz, LA;Fu, Y;Franz, T;Mohr, J;Gintschel, P;Berlin, H;Degen, A;Freier, S;Rygol, SM;Schraven, B;Kahlfuss, S;van Zandbergen, G;Müller, AJ;
    JCI insight
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  36. Triplication of the interferon receptor locus contributes to hallmarks of Down syndrome in a mouse model
    Authors: Waugh, KA;Minter, R;Baxter, J;Chi, C;Galbraith, MD;Tuttle, KD;Eduthan, NP;Kinning, KT;Andrysik, Z;Araya, P;Dougherty, H;Dunn, LN;Ludwig, M;Schade, KA;Tracy, D;Smith, KP;Granrath, RE;Busquet, N;Khanal, S;Anderson, RD;Cox, LL;Estrada, BE;Rachubinski, AL;Lyford, HR;Britton, EC;Fantauzzo, KA;Orlicky, DJ;Matsuda, JL;Song, K;Cox, TC;Sullivan, KD;Espinosa, JM;
    Nature genetics
    Species: Transgenic Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  37. Tumor-derived semaphorin 4A improves PD-1-blocking antibody efficacy by enhancing CD8+ T cell cytotoxicity and proliferation
    Authors: Naito, Y;Koyama, S;Masuhiro, K;Hirai, T;Uenami, T;Inoue, T;Osa, A;Machiyama, H;Watanabe, G;Sax, N;Villa, J;Kinugasa-Katayama, Y;Nojima, S;Yaga, M;Hosono, Y;Okuzaki, D;Satoh, S;Tsuda, T;Nakanishi, Y;Suga, Y;Morita, T;Fukushima, K;Nishide, M;Shiroyama, T;Miyake, K;Iwahori, K;Hirata, H;Nagatomo, I;Yano, Y;Tamiya, M;Kumagai, T;Takemoto, N;Inohara, H;Yamasaki, S;Yamashita, K;Aoshi, T;Akbay, EA;Hosen, N;Shintani, Y;Takamatsu, H;Mori, M;Takeda, Y;Kumanogoh, A;
    Science advances
    Species: Transgenic Mouse, Mouse
    Sample Types: Transduced Whole Cells, Transfected Whole Cells, Whole Cells
    Applications: Bioassay
  38. A novel cell-based screen identifies chemical entities that reverse the immune-escape phenotype of metastatic tumours
    Authors: Nohara, LL;Ellis, SLS;Dreier, C;Dada, S;Saranchova, I;Munro, L;Pfeifer, CG;Coyle, KM;Morrice, JR;Shim, DJS;Ahn, P;De Voogd, N;Williams, DE;Cheng, P;Garrovillas, E;Andersen, RJ;Jefferies, WA;
    Frontiers in pharmacology
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  39. Distinct Th17 effector cytokines differentially promote microglial and blood-brain barrier inflammatory responses during post-infectious encephalitis
    Authors: Wayne, CR;Bremner, L;Faust, TE;Dur�n-Laforet, V;Ampatey, N;Ho, SJ;Feinberg, PA;Arvanitis, P;Ciric, B;Ruan, C;Elyaman, W;Delaney, SL;Vargas, WS;Swedo, S;Menon, V;Schafer, DP;Cutforth, T;Agalliu, D;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  40. Identification of biomarkers for glycaemic deterioration in type 2 diabetes
    Authors: Slieker, RC;Donnelly, LA;Akalestou, E;Lopez-Noriega, L;Melhem, R;G�ne?, A;Abou Azar, F;Efanov, A;Georgiadou, E;Muniangi-Muhitu, H;Sheikh, M;Giordano, GN;�kerlund, M;Ahlqvist, E;Ali, A;Banasik, K;Brunak, S;Barovic, M;Bouland, GA;Burdet, F;Canouil, M;Dragan, I;Elders, PJM;Fernandez, C;Festa, A;Fitipaldi, H;Froguel, P;Gudmundsdottir, V;Gudnason, V;Gerl, MJ;van der Heijden, AA;Jennings, LL;Hansen, MK;Kim, M;Leclerc, I;Klose, C;Kuznetsov, D;Mansour Aly, D;Mehl, F;Marek, D;Melander, O;Niknejad, A;Ottosson, F;Pavo, I;Duffin, K;Syed, SK;Shaw, JL;Cabrera, O;Pullen, TJ;Simons, K;Solimena, M;Suvitaival, T;Wretlind, A;Rossing, P;Lyssenko, V;Legido Quigley, C;Groop, L;Thorens, B;Franks, PW;Lim, GE;Estall, J;Ibberson, M;Beulens, JWJ;'t Hart, LM;Pearson, ER;Rutter, GA;
    Nature communications
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  41. Conserved and cell type-specific transcriptional responses to IFN-gamma in the ventral midbrain
    Authors: BD Hobson, AT Stanley, MB De Los San, B Culbertson, EV Mosharov, PA Sims, D Sulzer
    Brain, Behavior, and Immunity, 2023-04-24;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Bioassay
  42. Single molecule analyses reveal dynamics of Salmonella translocated effector proteins in host cell endomembranes
    Authors: V Göser, N Sander, M Schulte, F Scharte, R Franzkoch, V Liss, OE Psathaki, M Hensel
    Nature Communications, 2023-03-04;14(1):1240.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  43. ATG16L1 protects from interferon-gamma-induced cell death in the small intestinal crypt
    Authors: EG Foerster, DKL Tsang, S Goyal, SJ Robertson, LM Robert, H Maughan, CJ Streutker, SE Girardin, DJ Philpott
    Mucosal Immunology, 2023-02-14;0(0):.
    Species: Transgenic Mouse
    Sample Types: Organoid
    Applications: Bioassay
  44. Otoprotective Effects of Fucoidan Reduce Cisplatin-Induced Ototoxicity in Mouse Cochlear UB/OC-2 Cells
    Authors: CY Hsieh, JN Lin, TY Kang, YH Wen, SH Yu, CC Wu, HP Wu
    International Journal of Molecular Sciences, 2023-02-10;24(4):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  45. Modulation of Skin Inflammatory Responses by Aluminum Adjuvant
    Authors: Y Liao, L Sun, M Nie, J Li, X Huang, S Heng, W Zhang, T Xia, Z Guo, Q Zhao, LJ Zhang
    Pharmaceutics, 2023-02-08;15(2):.
    Species: Mouse
    Sample Types:
  46. Upadacitinib inhibits corneal inflammation and neovascularization by suppressing M1 macrophage infiltration in the corneal alkali burn model
    Authors: J Yu, Y Shen, J Luo, J Jin, P Li, P Feng, H Guan
    International immunopharmacology, 2023-02-03;116(0):109680.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  47. Insulin Receptor Substrate 1 Signaling Inhibits Foxp3 Expression and Suppressive Functions in Treg Cells through the mTORC1 Pathway
    Authors: WH Lee, GE Kim, KJ Hong, HS Kim, GR Lee
    International Journal of Molecular Sciences, 2023-01-29;24(3):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  48. Immunoproteasome inhibition prevents progression of castration-resistant prostate cancer
    Authors: J Li, N Liu, H Zhou, P Xian, Y Song, X Tang, Y Li, M Basler
    British Journal of Cancer, 2023-01-21;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  49. Vitamin D Receptor Expression Limits the Angiogenic and Inflammatory Properties of Retinal Endothelial Cells
    Authors: YS Song, N Jamali, CM Sorenson, N Sheibani
    Cells, 2023-01-16;12(2):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  50. Facile repurposing of peptide-MHC-restricted antibodies for cancer immunotherapy
    Authors: X Yang, D Nishimiya, S Löchte, KM Jude, M Borowska, CS Savvides, M Dougan, L Su, X Zhao, J Piehler, KC Garcia
    Nature Biotechnology, 2023-01-02;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  51. Facile repurposing of peptide-MHC-restricted antibodies for cancer immunotherapy
    Authors: X Yang, D Nishimiya, S Löchte, KM Jude, M Borowska, CS Savvides, M Dougan, L Su, X Zhao, J Piehler, KC Garcia
    Nature Biotechnology, 2023;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  52. Single molecule analyses reveal dynamics of Salmonella translocated effector proteins in host cell endomembranes
    Authors: V Göser, N Sander, M Schulte, F Scharte, R Franzkoch, V Liss, OE Psathaki, M Hensel
    Nature Communications, 2023;14(1):1240.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  53. Insulin Receptor Substrate 1 Signaling Inhibits Foxp3 Expression and Suppressive Functions in Treg Cells through the mTORC1 Pathway
    Authors: WH Lee, GE Kim, KJ Hong, HS Kim, GR Lee
    International Journal of Molecular Sciences, 2023;24(3):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  54. Pancreatic Islet Cells Response to IFNgamma Relies on Their Spatial Location within an Islet
    Authors: M De Burghgr, C Lourenço, C Berthault, V Aiello, A Villalba, A Fouque, M Diedisheim, S You, M Oshima, R Scharfmann
    Cells, 2022-12-28;12(1):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  55. Astragaloside IV Targets Macrophages to Alleviate Renal Ischemia-Reperfusion Injury via the Crosstalk between Hif-1alpha and NF-kappaB (p65)/Smad7 Pathways
    Authors: L Tang, M Zhu, X Che, X Yang, Y Xu, Q Ma, M Zhang, Z Ni, X Shao, S Mou
    Journal of personalized medicine, 2022-12-27;13(1):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  56. A Near-Infrared Mechanically Switchable Elastomeric Film as a Dynamic Cell Culture Substrate
    Authors: G Spiaggia, P Taladriz-B, S Hengsberge, D Septiadi, C Geers, A Lee, B Rothen-Rut, A Petri-Fink
    Biomedicines, 2022-12-22;11(1):.
    Species: Mouse
    Sample Types: cell culture supernatant
    Applications: ELISA Control
  57. Zinc Transporter 8 Haploinsufficiency Protects Against Beta Cell Dysfunction in Type 1 Diabetes by Increasing Mitochondrial Respiration
    Authors: YK Kim, JA Walters, ND Moss, KL Wells, R Sheridan, JG Miranda, RKP Benninger, LL Pyle, RM O'Brien, L Sussel, HW Davidson
    Molecular Metabolism, 2022-11-05;66(0):101632.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  58. Circular RNA circBNC2 inhibits epithelial cell G2-M arrest to prevent fibrotic maladaptive repair
    Authors: P Wang, Z Huang, Y Peng, H Li, T Lin, Y Zhao, Z Hu, Z Zhou, W Zhou, Y Liu, FF Hou
    Nature Communications, 2022-10-31;13(1):6502.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  59. Desmoglein-2 is important for islet function and beta-cell survival
    Authors: KK Myo Min, D Rojas-Cana, D Penko, M DeNichilo, MP Cockshell, CB Ffrench, EJ Thompson, O Asplund, CJ Drogemulle, RB Prasad, L Groop, ST Grey, HE Thomas, T Loudovaris, TW Kay, MG Mahoney, CF Jessup, PT Coates, CS Bonder
    Cell Death & Disease, 2022-10-29;13(10):911.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  60. TNFalpha and IFNgamma cooperate for efficient pro- to anti-inflammatory transition of macrophages during muscle regeneration
    Authors: F Babaeijand, A Paiero, R Long, LW Tung, SP Smith, R Cheng, J Smandych, N Kajabadi, CK Chang, A Ghassemi, WDM Kennedy, H Soliman, PW Schutz, FMV Rossi
    Proceedings of the National Academy of Sciences of the United States of America, 2022-10-24;119(44):e2209976119.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  61. Visualizing inflammation with an M1 macrophage selective probe via GLUT1 as the gating target
    Authors: H Cho, HY Kwon, A Sharma, SH Lee, X Liu, N Miyamoto, JJ Kim, SH Im, NY Kang, YT Chang
    Nature Communications, 2022-10-10;13(1):5974.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  62. Detection of Radiolabeled Inflammatory Cell Macrophage Subpopulations in Chronic Respiratory Diseases: Results from Preliminary Analyses
    Authors: AP Shaik, AS Shaik, M Abudawood, A Al Faraj
    BioMed Research International, 2022-10-06;2022(0):9470845.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  63. Neuronally expressed PDL1, not PD1, suppresses acute nociception
    Authors: KA Meerschaer, BS Edwards, AY Epouhe, B Jefferson, R Friedman, OL Babyok, JK Moy, F Kehinde, C Liu, CJ Workman, DAA Vignali, KM Albers, HR Koerber, MS Gold, BM Davis, NN Scheff, JL Saloman
    Brain, Behavior, and Immunity, 2022-09-08;106(0):233-246.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  64. Synthetic mimetics assigned a major role to IFNAR2 in type I interferon signaling
    Authors: N Zoellner, N Coesfeld, FH De Vos, J Denter, HC Xu, E Zimmer, B Knebel, H Al-Hasani, S Mossner, PA Lang, DM Floss, J Scheller
    Frontiers in Microbiology, 2022-09-02;13(0):947169.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  65. Sex and APOE Genotype Alter the Basal and Induced Inflammatory States of Primary Microglia from APOE Targeted Replacement Mice
    Authors: I Mhatre-Win, A Eid, Y Han, K Tieu, JR Richardson
    International Journal of Molecular Sciences, 2022-08-29;23(17):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  66. Twist-related protein 1 induces epithelial-mesenchymal transition and renal fibrosis through the upregulation of complement 3
    Authors: T Otsuki, N Fukuda, L Chen, A Tsunemi, M Abe
    PLoS ONE, 2022-08-26;17(8):e0272917.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  67. NAD+ metabolism drives astrocyte proinflammatory reprogramming in central nervous system autoimmunity
    Authors: T Meyer, D Shimon, S Youssef, G Yankovitz, A Tessler, T Chernobyls, A Gaoni-Yoge, R Perelroize, N Budick-Har, L Steinman, L Mayo
    Proceedings of the National Academy of Sciences of the United States of America, 2022-08-22;119(35):e2211310119.
    Species: Mouse
    Sample Types: Whole Cell
    Applications: Cell Culture
  68. STUB1 is an intracellular checkpoint for interferon gamma sensing
    Authors: S Ng, S Lim, ACN Sim, R Mangadu, A Lau, C Zhang, SB Martinez, A Chandramoh, UM Lim, SSW Ho, SC Chang, P Gopal, LZ Hong, A Schwaid, AZ Fernandis, A Loboda, C Li, U Phan, B Henry, AW Partridge
    Scientific Reports, 2022-08-18;12(1):14087.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  69. IFN-gamma stimulated murine and human neurons mount anti-parasitic defenses against the intracellular parasite Toxoplasma gondii
    Authors: S Chandrasek, JA Kochanowsk, EF Merritt, JS Lagas, A Swannigan, AA Koshy
    Nature Communications, 2022-08-08;13(1):4605.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  70. Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia
    Authors: EG Vasquez, N Nasreddin, GN Valbuena, EJ Mulholland, HL Belnoue-Da, HR Eggington, RO Schenck, VM Wouters, P Wirapati, K Gilroy, TRM Lannagan, DJ Flanagan, AK Najumudeen, S Omwenga, AMB McCorry, A Easton, VH Koelzer, JE East, D Morton, L Trusolino, T Maughan, AD Campbell, MB Loughrey, PD Dunne, P Tsantoulis, DJ Huels, S Tejpar, OJ Sansom, SJ Leedham
    Cell Stem Cell, 2022-08-04;29(8):1213-1228.e8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  71. Small RNAs derived from tRNA fragmentation regulate the functional maturation of neonatal beta cells
    Authors: MB Bayazit, C Jacovetti, C Cosentino, J Sobel, K Wu, F Brozzi, A Rodriguez-, L Stoll, C Guay, R Regazzi
    Cell Reports, 2022-07-12;40(2):111069.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  72. Loss of MLKL ameliorates liver fibrosis by inhibiting hepatocyte necroptosis and hepatic stellate cell activation
    Authors: R Guo, X Jia, Z Ding, G Wang, M Jiang, B Li, S Chen, B Xia, Q Zhang, J Liu, R Zheng, Z Gao, X Xie
    Theranostics, 2022-07-04;12(11):5220-5236.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  73. An Iron Refractory Phenotype in Obese Adipose Tissue Macrophages Leads to Adipocyte Iron Overload
    Authors: MK Ameka, WN Beavers, CM Shaver, LB Ware, VE Kerchberge, KQ Schoenfelt, L Sun, T Koyama, EP Skaar, L Becker, AH Hasty
    International Journal of Molecular Sciences, 2022-07-03;23(13):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  74. Hematopoietic Prostaglandin D2 Synthase Controls Tfh/Th2 Communication and Limits Tfh Antitumor Effects
    Authors: R Mary, F Chalmin, T Accogli, M Bruchard, C Hibos, J Melin, C Truntzer, E Limagne, V Derangère, M Thibaudin, E Humblin, R Boidot, S Chevrier, L Arnould, C Richard, Q Klopfenste, A Bernard, Y Urade, JA Harker, L Apetoh, F Ghiringhel, F Végran
    Cancer Immunology Research, 2022-07-01;0(0):OF1-OF17.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  75. 3-oxo-C12:2-HSL, quorum sensing molecule from human intestinal microbiota, inhibits pro-inflammatory pathways in immune cells via bitter taste receptors
    Authors: G Coquant, D Aguanno, L Brot, C Belloir, J Delugeard, N Roger, HP Pham, L Briand, M Moreau, L de Sordi, V Carrière, JP Grill, S Thenet, P Seksik
    Oncogene, 2022-06-08;12(1):9440.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  76. Transcriptomic Profiling Reveals That HMGB1 Induces Macrophage Polarization Different from Classical M1
    Authors: H Qu, R Heinbäck, H Salo, E Ewing, A Espinosa, C Aulin, H Erlandsson
    Biomolecules, 2022-06-02;12(6):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  77. Semaphorin 3A regulates alveolar bone remodeling on orthodontic tooth movement
    Authors: H Kamei, T Ishii, Y Nishii
    Oncogene, 2022-06-02;12(1):9243.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  78. Novel role for caspase 1 inhibitor VX765 in suppressing NLRP3 inflammasome assembly and atherosclerosis via promoting mitophagy and efferocytosis
    Authors: Y Jin, Y Liu, L Xu, J Xu, Y Xiong, Y Peng, K Ding, S Zheng, N Yang, Z Zhang, L Li, L Tan, H Song, J Fu
    Cell Death & Disease, 2022-05-31;13(5):512.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  79. A TLR4-independent critical role for CD14 in intracellular LPS sensing
    Authors: SO Vasudevan, AJ Russo, P Kumari, SK Vanaja, VA Rathinam
    Cell Reports, 2022-05-03;39(5):110755.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  80. Deficiency in coatomer complex I causes aberrant activation of STING signalling
    Authors: A Steiner, K Hrovat-Sch, I Prigione, CH Yu, P Laohamonth, CR Harapas, RRJ Low, D De Nardo, LF Dagley, MJ Mlodzianos, KL Rogers, T Zillinger, G Hartmann, MP Gantier, M Gattorno, M Geyer, S Volpi, S Davidson, SL Masters
    Nature Communications, 2022-04-28;13(1):2321.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  81. PD-L1 signaling selectively regulates T cell lymphatic transendothelial migration
    Authors: W Piao, L Li, V Saxena, J Iyyathurai, R Lakhan, Y Zhang, IT Lape, C Paluskievi, KL Hippen, Y Lee, E Silverman, MW Shirkey, LV Riella, BR Blazar, JS Bromberg
    Nature Communications, 2022-04-21;13(1):2176.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  82. Citrullination of glucokinase is linked to autoimmune diabetes
    Authors: ML Yang, S Horstman, R Gee, P Guyer, TT Lam, J Kanyo, AL Perdigoto, C Speake, CJ Greenbaum, A Callebaut, L Overbergh, RG Kibbey, KC Herold, EA James, MJ Mamula
    Nature Communications, 2022-04-06;13(1):1870.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  83. Inhibiting Type I arginine methyltransferase activity promotes the T cell mediated antitumor immune response
    Authors: A Fedoriw, L Shi, S O'Brien, KN Smitheman, Y Wang, J Hou, C Sherk, S Rajapurkar, J Laraio, LJ Williams, C Xu, G Han, Q Feng, MT Bedford, L Wang, O Barbash, RG Kruger, P Hwu, HP Mohammad, W Peng
    Cancer Immunology Research, 2022-04-01;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  84. The transmembrane adaptor SCIMP recruits tyrosine kinase Syk to phosphorylate Toll-like receptors to mediate selective inflammatory outputs
    Authors: L Liu, RM Lucas, JD Nanson, Y Li, J Whitfield, JEB Curson, N Tuladhar, K Alexandrov, M Mobli, MJ Sweet, B Kobe, J Stow, L Luo
    The Journal of Biological Chemistry, 2022-03-22;0(0):101857.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  85. Ferroptosis as a Novel Determinant of beta-Cell Death in Diabetic Conditions
    Authors: A Stancic, T Saksida, M Markelic, M Vucetic, I Grigorov, V Martinovic, D Gajic, A Ivanovic, K Velickovic, N Savic, V Otasevic
    Oxidative Medicine and Cellular Longevity, 2022-03-14;2022(0):3873420.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Cell Culture
  86. Recruitment and training of alveolar macrophages after pneumococcal pneumonia
    Authors: EI Arafa, AT Shenoy, KA Barker, NS Etesami, IM Martin, C Lyon De An, E Na, CV Odom, WN Goltry, FT Korkmaz, AK Wooten, AC Belkina, A Guillon, EC Forsberg, MR Jones, LJ Quinton, JP Mizgerd
    JCI Insight, 2022-03-08;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  87. Superantigens promote Staphylococcus aureus bloodstream infection by eliciting pathogenic interferon-gamma production
    Authors: SW Tuffs, MI Goncheva, SX Xu, HC Craig, KJ Kasper, J Choi, RS Flannagan, SM Kerfoot, DE Heinrichs, JK McCormick
    Proceedings of the National Academy of Sciences of the United States of America, 2022-02-22;119(8):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  88. PD-L1 near Infrared Photoimmunotherapy of Ovarian Cancer Model
    Authors: J Jin, I Sivakumar, Y Mironchik, B Krishnamac, F Wildes, JD Barnett, CF Hung, S Nimmagadda, H Kobayashi, ZM Bhujwalla, MF Penet
    Cancers, 2022-01-26;14(3):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  89. Insights from Dysregulated mRNA Expression Profile of beta-Cells in Response to Proinflammatory Cytokines
    Authors: Z Wang, K Huang, J Xu, J Liu, Y Zheng
    Journal of Immunology Research, 2022-01-22;2022(0):4542487.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  90. CXCR4 induces podocyte injury and proteinuria by activating beta-catenin signaling
    Authors: H Mo, Q Ren, D Song, B Xu, D Zhou, X Hong, FF Hou, L Zhou, Y Liu
    Theranostics, 2022-01-01;12(2):767-781.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  91. Dynamic changes in beta-cell [Ca2+] regulates NFAT activation, gene transcription and islet gap junction communication
    Authors: JG Miranda, WE Schleicher, KL Wells, DG Ramirez, SP Landgrave, RK Benninger
    Oncogene, 2021-12-31;0(0):101430.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  92. Gene network modeling via TopNet reveals functional dependencies between diverse tumor-critical mediator genes
    Authors: HR McMurray, A Ambeskovic, LA Newman, J Aldersley, V Balakrishn, B Smith, HA Stern, H Land, MN McCall
    Cell Reports, 2021-12-21;37(12):110136.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  93. Glucose metabolism and pyruvate carboxylase enhance glutathione synthesis and restrict oxidative stress in pancreatic islets
    Authors: A Fu, L van Rooyen, L Evans, N Armstrong, D Avizonis, T Kin, GH Bird, A Reddy, ET Chouchani, M Liesa-Roig, LD Walensky, AMJ Shapiro, NN Danial
    Cell Reports, 2021-11-23;37(8):110037.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  94. The APPL1-Rab5 axis restricts NLRP3 inflammasome activation through early endosomal-dependent mitophagy in macrophages
    Authors: KKL Wu, K Long, H Lin, PMF Siu, RLC Hoo, D Ye, A Xu, KKY Cheng
    Nature Communications, 2021-11-17;12(1):6637.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  95. Differential Cytokine-Induced Responses of Polarized Microglia
    Authors: P Chauhan, WS Sheng, S Hu, S Prasad, JR Lokensgard
    Brain sciences, 2021-11-10;11(11):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  96. Regulation of intestinal immunity and tissue repair by enteric glia
    Authors: F Progatzky, M Shapiro, SH Chng, B Garcia-Cas, CH Classon, S Sevgi, A Laddach, AC Bon-Frauch, R Lasrado, M Rahim, EM Amaniti, S Boeing, K Shah, LJ Entwistle, A Suárez-Bon, MS Wilson, B Stockinger, V Pachnis
    Nature, 2021-10-20;599(7883):125-130.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  97. In situ-formed adhesive hyaluronic acid hydrogel with prolonged amnion-derived conditioned medium release for diabetic wound repair
    Authors: Y Zhang, Y Zheng, F Shu, R Zhou, B Bao, S Xiao, K Li, Q Lin, L Zhu, Z Xia
    Carbohydrate polymers, 2021-10-16;276(0):118752.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  98. Lung Fibrosis Is Improved by Extracellular Vesicles from IFNgamma-Primed Mesenchymal Stromal Cells in Murine Systemic Sclerosis
    Authors: P Rozier, M Maumus, ATJ Maria, K Toupet, C Jorgensen, P Guilpain, D Noël
    Cells, 2021-10-13;10(10):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  99. Tumor-Released Products Promote Bone Marrow-Derived Macrophage Survival and Proliferation
    Authors: JM Motta, VM Rumjanek, A Mantovani, M Locati
    Biomedicines, 2021-10-04;9(10):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Differentiation, Differentiation
  100. Interleukin-4 and interleukin-13 induce different metabolic profiles in microglia and macrophages that relate with divergent outcomes after spinal cord injury
    Authors: J Amo-Aparic, J Garcia-Gar, I Francos-Qu, A Urpi, A Esteve-Cod, M Gut, A Quintana, R Lopez-Vale
    Theranostics, 2021-10-03;11(20):9805-9820.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  101. A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis
    Authors: G Wang, L Xie, B Li, W Sang, J Yan, J Li, H Tian, W Li, Z Zhang, Y Tian, Y Dai
    Nature Communications, 2021-09-30;12(1):5733.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  102. Potent Nrf2-inducing, antioxidant, and anti-inflammatory effects and identification of constituents validate the anti-cancer use of Uvaria chamae and Olax subscorpioidea
    Authors: TD Popoola, ST Guetchueng, KJ Ritchie, O Awodele, NM Dempster, O Akinloye, SD Sarker, AA Fatokun
    BMC complementary medicine and therapies, 2021-09-18;21(1):234.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  103. Intestinal antiviral signaling is controlled by autophagy gene Epg5 independent of the microbiota
    Authors: S Lee, G Kalugotla, H Ingle, R Rodgers, C Wu, Y Wang, Y Li, X Yang, J Zhang, NR Borella, H Deng, L Droit, R Hill, ST Peterson, C Desai, D Lawrence, Q Lu, MT Baldridge
    Autophagy, 2021-09-14;0(0):1-16.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  104. Macrophages target Listeria monocytogenes by two discrete non-canonical autophagy pathways
    Authors: A Gluschko, A Farid, M Herb, D Grumme, M Krönke, M Schramm
    Autophagy, 2021-09-05;0(0):1-15.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  105. The Cholinergic Anti-Inflammatory Pathway Attenuates the Development of Atherosclerosis in Apoe-/- Mice through Modulating Macrophage Functions
    Authors: Z Qian, H Yang, H Li, C Liu, L Yang, Z Qu, X Li
    Biomedicines, 2021-09-03;9(9):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  106. Mitochondrial Targeting of the Ammonia-Sensitive Uncoupler SLC4A11 by the Chaperone-Mediated Carrier Pathway in Corneal Endothelium
    Authors: M Choi, JA Bonanno
    Investigative Ophthalmology & Visual Science, 2021-09-02;62(12):4.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  107. TCF-1 controls Treg cell functions that regulate inflammation, CD8+ T cell cytotoxicity and severity of colon cancer
    Authors: A Osman, B Yan, Y Li, KD Pavelko, J Quandt, A Saadalla, MP Singh, M Kazemian, F Gounari, K Khazaie
    Nature Immunology, 2021-08-12;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  108. alpha-Hydroxyisocaproic Acid Decreases Protein Synthesis but Attenuates TNFalpha/IFNgamma Co-Exposure-Induced Protein Degradation and Myotube Atrophy via Suppression of iNOS and IL-6 in Murine C2C12 Myotube
    Authors: K Sumi, M Sakuda, K Munakata, K Nakamura, K Ashida
    Nutrients, 2021-07-13;13(7):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  109. Pharmacological or genetic inhibition of iNOS prevents cachexia-mediated muscle wasting and its associated metabolism defects
    Authors: J Sadek, DT Hall, B Colalillo, A Omer, AK Tremblay, V Sanguin-Ge, W Muller, S Di Marco, ME Bianchi, IE Gallouzi
    Embo Molecular Medicine, 2021-06-07;0(0):e13591.
    Species: Mouse
    Sample Types: Organoid
    Applications: Bioassay
  110. Protective Effects of Complement Component 8 Gamma Against Blood-Brain Barrier Breakdown
    Authors: JH Kim, J Han, K Suk
    Frontiers in Physiology, 2021-06-03;12(0):671250.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Cultulre
  111. STAT1 potentiates oxidative stress revealing a targetable vulnerability that increases phenformin efficacy in breast cancer
    Authors: SP Totten, YK Im, E Cepeda Cañ, O Najyb, A Nguyen, S Hébert, R Ahn, K Lewis, B Lebeau, R La Selva, V Sabourin, C Martínez, P Savage, H Kuasne, D Avizonis, N Santos Mar, C Chabot, A Aguilar-Ma, ML Goulet, M Dankner, M Witcher, K Petrecca, M Basik, M Pollak, I Topisirovi, R Lin, PM Siegel, CL Kleinman, M Park, J St-Pierre, J Ursini-Sie
    Nature Communications, 2021-06-03;12(1):3299.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  112. Short lifespan of syngeneic transplanted MSC is a consequence of in vivo apoptosis and immune cell recruitment in mice
    Authors: MB Preda, CA Neculachi, IM Fenyo, AM Vacaru, MA Publik, M Simionescu, A Burlacu
    Cell Death & Disease, 2021-06-02;12(6):566.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  113. The YAP/HIF-1&alpha/miR-182/EGR2 axis is implicated in asthma severity through the control of Th17 cell differentiation
    Authors: J Zhou, N Zhang, W Zhang, C Lu, F Xu
    Cell & bioscience, 2021-05-12;11(1):84.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  114. The ubiquitylation of IL-1&beta limits its cleavage by caspase-1 and targets it for proteasomal degradation
    Authors: SL Vijayaraj, R Feltham, M Rashidi, D Frank, Z Liu, DS Simpson, G Ebert, A Vince, MJ Herold, A Kueh, JS Pearson, LF Dagley, JM Murphy, AI Webb, KE Lawlor, JE Vince
    Nature Communications, 2021-05-11;12(1):2713.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  115. Intertumoral Genetic Heterogeneity Generates Distinct Tumor Microenvironments in a Novel Murine Synchronous Melanoma Model
    Authors: SS Qin, BJ Han, A Williams, KM Jackson, R Jewell, AC Chacon, EM Lord, DC Linehan, M Kim, A Reuben, SA Gerber, PA Prieto
    Cancers, 2021-05-11;13(10):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  116. Involvement of circRNAs in Proinflammatory Cytokines-Mediated &beta-Cell Dysfunction
    Authors: Z Wang, C Deng, Y Zheng
    Mediators of Inflammation, 2021-05-04;2021(0):5566453.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  117. N4BP1 negatively regulates NF-&kappaB by binding and inhibiting NEMO oligomerization
    Authors: H Shi, L Sun, Y Wang, A Liu, X Zhan, X Li, M Tang, P Anderton, S Hildebrand, J Quan, S Ludwig, EMY Moresco, B Beutler
    Nature Communications, 2021-03-02;12(1):1379.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  118. CD39+PD-1+CD8+ T cells mediate metastatic dormancy in breast cancer
    Authors: P Tallón de, H Castañón, M Vermeer, N Núñez, K Silina, B Sobottka, J Urdinez, V Cecconi, H Yagita, F Movahedian, S Hiltbrunne, I Glarner, H Moch, S Tugues, B Becher, M van den Br
    Nature Communications, 2021-02-03;12(1):769.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  119. Signal-transducing adaptor protein-2 delays recovery of B lineage lymphocytes during hematopoietic stress
    Authors: M Ichii, K Oritani, J Toda, H Saito, H Shi, H Shibayama, D Motooka, Y Kitai, R Muromoto, JI Kashiwakur, K Saitoh, D Okuzaki, T Matsuda, Y Kanakura
    Haematologica, 2021-02-01;0(0):.
    Species: Mouse
    Sample Types: Whole Cell
    Applications: Cell Culture
  120. T-bet-dependent ILC1- and NK cell-derived IFN-&gamma mediates cDC1-dependent host resistance against Toxoplasma gondii
    Authors: AH López-Ygle, E Burger, E Camanzo, AT Martin, AM Araujo, SF Kwok, F Yarovinsky
    PloS Pathogens, 2021-01-19;17(1):e1008299.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Bioassay
  121. Gut-licensed IFN&gamma+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes
    Authors: LM Sanmarco, MA Wheeler, C Gutiérrez-, CM Polonio, M Linnerbaue, FA Pinho-Ribe, Z Li, F Giovannoni, KV Batterman, G Scalisi, SEJ Zandee, ES Heck, M Alsuwailm, DL Rosene, B Becher, IM Chiu, A Prat, FJ Quintana
    Nature, 2021-01-06;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  122. The ATP synthase inhibition induces an AMPK-dependent glycolytic switch of mesenchymal stem cells that enhances their immunotherapeutic potential
    Authors: R Contreras-, R Elizondo-V, N Luque-Camp, MJ Torres, C Pradenas, G Tejedor, MJ Paredes-Ma, AM Vega-Lette, M Campos-Mor, Y Rigual-Gon, K Oyarce, M Salgado, C Jorgensen, M Khoury, MLÁ Garcia-Rob, C Altamirano, F Djouad, P Luz-Crawfo
    Theranostics, 2021-01-01;11(1):445-460.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  123. Bergenin protects pancreatic beta cells against cytokine-induced apoptosis in INS-1E cells
    Authors: SA Rajput, MR Mirza, MI Choudhary
    PLoS ONE, 2020-12-21;15(12):e0241349.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  124. In Vivo Bactericidal Efficacy of GWH1 Antimicrobial Peptide Displayed on Protein Nanoparticles, a Potential Alternative to Antibiotics
    Authors: JV Carratalá, E Brouillett, N Serna, A Sánchez-Ch, JM Sánchez, A Villaverde, A Arís, E Garcia-Fru, N Ferrer-Mir, F Malouin
    Pharmaceutics, 2020-12-17;12(12):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  125. JAK1 Inhibition Blocks Lethal Immune Hypersensitivity in a Mouse Model of Down Syndrome
    Authors: KD Tuttle, KA Waugh, P Araya, R Minter, DJ Orlicky, M Ludwig, Z Andrysik, MA Burchill, BAJ Tamburini, C Sempeck, K Smith, R Granrath, D Tracy, J Baxter, JM Espinosa, KD Sullivan
    Cell Rep, 2020-11-17;33(7):108407.
    Species: Mouse
    Sample Types: Plasma
    Applications: Cell Culture
  126. Serum amyloid A-containing HDL binds adipocyte-derived versican and macrophage-derived biglycan, reducing its anti-inflammatory properties
    Authors: CY Han, I Kang, M Omer, S Wang, T Wietecha, TN Wight, A Chait
    JCI Insight, 2020-09-24;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  127. The innate immunity protein IFITM3 modulates &gamma-secretase in Alzheimer's disease
    Authors: JY Hur, GR Frost, X Wu, C Crump, SJ Pan, E Wong, M Barros, T Li, P Nie, Y Zhai, JC Wang, J Tcw, L Guo, A McKenzie, C Ming, X Zhou, M Wang, Y Sagi, AE Renton, BT Esposito, Y Kim, KR Sadleir, I Trinh, RA Rissman, R Vassar, B Zhang, DS Johnson, E Masliah, P Greengard, A Goate, YM Li
    Nature, 2020-09-02;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  128. Ectonucleotidases from trypomastigotes from different sources and various genetic backgrounds of Trypanosoma cruzi potentiate their infectivity and host inflammation
    Authors: ALJ Leite, DS Oliveira, LWR Mota, LCF Carvalho, FF Zimmermann, NCN Paiva, PMA Vieira, M de Lana, LCC Afonso, A Talvani
    Cytokine, 2020-08-28;136(0):155255.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  129. Development of syngeneic murine cell lines for use in immunocompetent orthotopic lung cancer models
    Authors: K Nolan, G Verzosa, T Cleaver, D Tippimanch, LN DePledge, XJ Wang, C Young, A Le, R Doebele, H Li, SP Malkoski
    Cancer Cell Int., 2020-08-28;20(0):417.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  130. Mitofusin 2 in Macrophages Links Mitochondrial ROS Production, Cytokine Release, Phagocytosis, Autophagy, and Bactericidal Activity
    Authors: J Tur, S Pereira-Lo, T Vico, EA Marín, JP Muñoz, M Hernández-, PJ Cardona, A Zorzano, J Lloberas, A Celada
    Cell Rep, 2020-08-25;32(8):108079.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  131. Lipid mediators and biomarkers associated with type 1 diabetes development
    Authors: AJ Nelson, DJ Stephenson, RN Bone, CL Cardona, MA Park, YG Tusing, X Lei, G Kokotos, CL Graves, CE Mathews, J Kramer, MJ Hessner, CE Chalfant, S Ramanadham
    JCI Insight, 2020-08-20;5(16):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  132. Unique molecular characteristics of visceral afferents arising from different levels of the neuraxis: location of afferent somata predicts function and stimulus detection modalities
    Authors: KA Meerschaer, PC Adelman, RL Friedman, KM Albers, HR Koerber, BM Davis
    J. Neurosci., 2020-08-19;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay, Cell Culture
  133. Triacylglycerol synthesis enhances macrophage inflammatory function
    Authors: A Castoldi, LB Monteiro, N van Teijli, DE Sanin, N Rana, M Corrado, AM Cameron, F Hässler, M Matsushita, G Caputa, RI Klein Gelt, J Büscher, J Edwards-Hi, EL Pearce, EJ Pearce
    Nat Commun, 2020-08-14;11(1):4107.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  134. Lipopolysaccharide administration for a mouse model of cerebellar ataxia with neuroinflammation
    Authors: J Hong, D Yoon, Y Nam, D Seo, JH Kim, MS Kim, TY Lee, KS Kim, PW Ko, HW Lee, K Suk, SR Kim
    Sci Rep, 2020-08-07;10(1):13337.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  135. MEK5/ERK5 signaling mediates IL-4-induced M2 macrophage differentiation through regulation of c-Myc expression
    Authors: JPM Luiz, JE Toller-Kaw, PR Viacava, DC Nascimento, PT Pereira, AL Saraiva, DS Prado, M LeBert, E Giurisato, C Tournier, TM Cunha, FQ Cunha, V Quesniaux, B Ryffel, JC Alves-Filh
    J. Leukoc. Biol., 2020-08-03;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  136. Epigenetic transcriptional reprogramming by WT1 mediates a repair response during podocyte injury
    Authors: S Ettou, YL Jung, T Miyoshi, D Jain, K Hiratsuka, V Schumacher, ME Taglienti, R Morizane, PJ Park, JA Kreidberg
    Sci Adv, 2020-07-24;6(30):eabb5460.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  137. Lipopolysaccharide promotes Drp1-dependent mitochondrial fission and associated inflammatory responses in macrophages
    Authors: R Kapetanovi, SF Afroz, D Ramnath, GM Lawrence, T Okada, JE Curson, J de Bruin, DP Fairlie, K Schroder, JC St John, A Blumenthal, MJ Sweet
    Immunol. Cell Biol., 2020-07-20;0(0):.
    Species: Mouse
    Sample Types: Cells
    Applications: Cell Culture
  138. Ciliary proteins specify the cell inflammatory response by tuning NF&kappaB signalling, independently of primary cilia
    Authors: M Mc Fie, L Koneva, I Collins, CR Coveney, AM Clube, A Chanalaris, TL Vincent, JS Bezbradica, SN Sansom, AKT Wann
    J. Cell. Sci., 2020-07-08;133(13):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  139. Otoprotective Effect of 2,3,4',5-Tetrahydroxystilbene-2-O-&beta-d-Glucoside on Gentamicin-Induced Apoptosis in Mouse Cochlear UB/OC-2 Cells
    Authors: YH Wen, JN Lin, RS Wu, SH Yu, CJ Hsu, GF Tseng, HP Wu
    Molecules, 2020-07-06;25(13):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  140. T Cell-Intrinsic IRF5 Regulates T Cell Signaling, Migration, and Differentiation and Promotes Intestinal Inflammation
    Authors: J Yan, SP Pandey, BJ Barnes, JR Turner, C Abraham
    Cell Rep, 2020-06-30;31(13):107820.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  141. Adipocyte-Derived Versican and Macrophage-Derived Biglycan Control Adipose Tissue Inflammation in Obesity
    Authors: CY Han, I Kang, IA Harten, JA Gebe, CK Chan, M Omer, KM Alonge, LJ den Hartig, D Gomes Kjer, L Goodspeed, S Subramania, S Wang, F Kim, DE Birk, TN Wight, A Chait
    Cell Rep, 2020-06-30;31(13):107818.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  142. Molecules from American Ginseng Suppress Colitis through Nuclear Factor Erythroid-2-Related Factor 2
    Authors: A Chaparala, H Tashkandi, AA Chumanevic, EE Witalison, A Windust, T Cui, M Nagarkatti, P Nagarkatti, LJ Hofseth
    Nutrients, 2020-06-21;12(6):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  143. A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction
    Authors: JM Hildebrand, M Kauppi, IJ Majewski, Z Liu, AJ Cox, S Miyake, EJ Petrie, MA Silk, Z Li, MC Tanzer, G Brumatti, SN Young, C Hall, SE Garnish, J Corbin, MD Stutz, L Di Rago, P Gangatirka, EC Josefsson, K Rigbye, H Anderton, JA Rickard, A Tripaydoni, J Sheridan, TS Scerri, VE Jackson, PE Czabotar, JG Zhang, L Varghese, CC Allison, M Pellegrini, GM Tannahill, EC Hatchell, TA Willson, D Stockwell, CA de Graaf, J Collinge, A Hilton, N Silke, SK Spall, D Chau, V Athanasopo, D Metcalf, RM Laxer, AG Bassuk, BW Darbro, MA Fiatarone, N Vlahovich, D Hughes, M Kozlovskai, DB Ascher, K Warnatz, N Venhoff, J Thiel, C Biben, S Blum, J Reveille, MS Hildebrand, CG Vinuesa, P McCombe, MA Brown, BT Kile, C McLean, M Bahlo, SL Masters, H Nakano, PJ Ferguson, JM Murphy, WS Alexander, J Silke
    Nat Commun, 2020-06-19;11(1):3150.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  144. Immunopathology in schistosomiasis is regulated by TLR2,4- and IFN-gamma-activated MSC through modulating Th1/Th2 responses
    Authors: C Liu, YS Zhang, F Chen, XY Wu, BB Zhang, ZD Wu, JX Lei
    Stem Cell Res Ther, 2020-06-05;11(1):217.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  145. Panaxynol, a bioactive component of American ginseng, targets macrophages and suppresses colitis in mice
    Authors: A Chaparala, D Poudyal, H Tashkandi, EE Witalison, AA Chumanevic, JL Hofseth, I Nguyen, O Hardy, DL Pittman, MD Wyatt, A Windust, EA Murphy, M Nagarkatti, P Nagarkatti, LJ Hofseth
    Oncotarget, 2020-06-02;11(22):2026-2036.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  146. Microbiota-driven interleukin-17 production provides immune protection against invasive candidiasis
    Authors: M Li, C Li, X Wu, T Chen, L Ren, B Xu, J Cao
    Crit Care, 2020-05-27;24(1):268.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  147. Paracrine regulation and improvement of &beta-cell function by thioredoxin
    Authors: EM Hanschmann, SF Petry, S Eitner, CC Maresch, N Lingwal, CH Lillig, T Linn
    Redox Biol, 2020-05-16;34(0):101570.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  148. Role of pyruvate kinase M2-mediated metabolic reprogramming during podocyte differentiation
    Authors: Q Yuan, J Miao, Q Yang, L Fang, Y Fang, H Ding, Y Zhou, L Jiang, C Dai, K Zen, Q Sun, J Yang
    Cell Death Dis, 2020-05-11;11(5):355.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  149. Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection.
    Authors: Bosteels C, Neyt K, Vanheerswynghels M, van Helden M, Sichien D, Debeuf N, De Prijck S, Bosteels V, Vandamme N, Martens L, Saeys Y, Louagie E, Lesage M, Williams D, Tang S, Mayer J, Ronchese F, Scott C, Hammad H, Guilliams M, Lambrecht B
    Immunity, 2020-05-08;0(0):.
    Species: Mouse
    Sample Types: cell culture
  150. Bim expression modulates the pro-inflammatory phenotype of retinal astroglial cells
    Authors: J Falero-Per, N Sheibani, CM Sorenson
    PLoS ONE, 2020-05-04;15(5):e0232779.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  151. 2,3,4',5-Tetrahydroxystilbene-2-O-&beta-D-Glucoside (THSG) Activates the Nrf2 Antioxidant Pathway and Attenuates Oxidative Stress-Induced Cell Death in Mouse Cochlear UB/OC-2 Cells
    Authors: TY Wu, JN Lin, ZY Luo, CJ Hsu, JS Wang, HP Wu
    Biomolecules, 2020-03-18;10(3):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  152. Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis
    Authors: R Kumar, PT Bunn, SS Singh, SS Ng, M Montes de, F De Labasti, SB Chauhan, N Singh, RJ Faleiro, CL Edwards, TCM Frame, M Sheel, RJ Austin, SW Lane, T Bald, MJ Smyth, GR Hill, SE Best, A Haque, D Corvino, N Waddell, L Koufarioti, P Mukhopadha, M Rai, J Chakravart, OP Singh, D Sacks, S Nylen, J Uzonna, S Sundar, CR Engwerda
    Cell Rep, 2020-02-25;30(8):2512-2525.e9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  153. CCL2 and CXCL12 Derived from Mesenchymal Stromal Cells Cooperatively Polarize IL-10+ Tissue Macrophages to Mitigate Gut Injury
    Authors: J Giri, R Das, E Nylen, R Chinnadura, J Galipeau
    Cell Rep, 2020-02-11;30(6):1923-1934.e4.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  154. N6-methyladenosine demethylase FTO promotes M1 and M2 macrophage activation
    Authors: X Gu, Y Zhang, D Li, H Cai, L Cai, Q Xu
    Cell. Signal., 2020-02-01;0(0):109553.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  155. Hepatic ILC2 activity is regulated by liver inflammation-induced cytokines and effector CD4+ T cells
    Authors: S Steinmann, M Schoedsack, F Heinrich, PC Breda, A Ochel, G Tiegs, K Neumann
    Sci Rep, 2020-01-23;10(1):1071.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  156. Essential Role of mGBP7 for Survival of Toxoplasma gondii Infection
    Authors: N Steffens, C Beuter-Gun, E Kravets, A Reich, L Legewie, K Pfeffer, D Degrandi
    MBio, 2020-01-21;11(1):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  157. Cycling hypoxia promotes a pro-inflammatory phenotype in macrophages via JNK/p65 signaling pathway
    Authors: V Delprat, C Tellier, C Demazy, M Raes, O Feron, C Michiels
    Sci Rep, 2020-01-21;10(1):882.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  158. B Cell Endosomal RAB7 Promotes TRAF6 K63 Polyubiquitination and NF-kappaB Activation for Antibody Class-Switching
    Authors: H Yan, M Fernandez, J Wang, S Wu, R Wang, Z Lou, JB Moroney, CE Rivera, JR Taylor, H Gan, H Zan, D Kolvaskyy, D Liu, P Casali, Z Xu
    J. Immunol., 2020-01-13;204(5):1146-1157.
    Species: Transgenic Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  159. Anti-PD-1 antibody decreases tumour-infiltrating regulatory T cells
    Authors: K Yoshida, M Okamoto, J Sasaki, C Kuroda, H Ishida, K Ueda, H Ideta, T Kamanaka, A Sobajima, T Takizawa, M Tanaka, K Aoki, T Uemura, H Kato, H Haniu, N Saito
    BMC Cancer, 2020-01-08;20(1):25.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  160. The combination of Radix Astragali and Radix Angelicae Sinensis attenuates the IFN-gamma-induced immune destruction of hematopoiesis in bone marrow cells
    Authors: J Liu, J Wei, C Wang, X Meng, H Chen, P Deng, M Huandike, H Zhang, X Li, L Chai
    BMC Complement Altern Med, 2019-12-09;19(1):356.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  161. IL-33 deficiency causes persistent inflammation and severe neurodegeneration in retinal detachment
    Authors: J Augustine, S Pavlou, I Ali, K Harkin, E Ozaki, M Campbell, AW Stitt, H Xu, M Chen
    J Neuroinflammation, 2019-12-03;16(1):251.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  162. Maternal Type-I interferon signaling adversely affects the microglia and the behavior of the offspring accompanied by increased sensitivity to stress
    Authors: H Ben-Yehuda, O Matcovitch, A Kertser, A Spinrad, M Prinz, I Amit, M Schwartz
    Mol. Psychiatry, 2019-11-26;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  163. A20 as an immune tolerance factor can determine islet transplant outcomes
    Authors: NW Zammit, SN Walters, KL Seeberger, PJ O'Connell, GS Korbutt, ST Grey
    JCI Insight, 2019-11-01;4(21):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  164. Metabolic regulation of gene expression by histone lactylation
    Authors: D Zhang, Z Tang, H Huang, G Zhou, C Cui, Y Weng, W Liu, S Kim, S Lee, M Perez-Neut, J Ding, D Czyz, R Hu, Z Ye, M He, YG Zheng, HA Shuman, L Dai, B Ren, RG Roeder, L Becker, Y Zhao
    Nature, 2019-10-23;574(7779):575-580.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  165. The combination of Cytokines and albendazole therapy for prophylaxis and treatment of experimental./hydatid cyst
    Authors: M Rahdar, A Rafiei, R Valipour-N
    Acta Trop., 2019-10-02;201(0):105206.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  166. Lung endothelial cell antigen cross-presentation to CD8+T cells drives malaria-associated lung injury
    Authors: C Claser, SYT Nguee, A Balachande, S Wu Howland, E Becht, B Gunasegara, SV Hartimath, AWQ Lee, J Theng Then, C Bing Ong, EW Newell, J Goggi, L Guan Ng, L Renia
    Nat Commun, 2019-09-18;10(1):4241.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  167. Macrophage miR-34a Is a Key Regulator of Cholesterol Efflux and Atherosclerosis
    Authors: Y Xu, Y Xu, Y Zhu, H Sun, C Juguilon, F Li, D Fan, L Yin, Y Zhang
    Mol. Ther., 2019-09-12;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  168. Phlda3 regulates beta cell survival during stress
    Authors: M Bensellam, JY Chan, K Lee, MV Joglekar, AA Hardikar, T Loudovaris, HE Thomas, JC Jonas, DR Laybutt
    Sci Rep, 2019-09-06;9(1):12827.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  169. Blunting neuroinflammation with resolvin D1 prevents early pathology in a rat model of Parkinson's disease
    Authors: P Krashia, A Cordella, A Nobili, L La Barbera, M Federici, A Leuti, F Campanelli, G Natale, G Marino, V Calabrese, F Vedele, V Ghiglieri, B Picconi, G Di Lazzaro, T Schirinzi, G Sancesario, N Casadei, O Riess, S Bernardini, A Pisani, P Calabresi, MT Viscomi, CN Serhan, V Chiurchiù, M D'Amelio, NB Mercuri
    Nat Commun, 2019-09-02;10(1):3945.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  170. Acidity promotes tumour progression by altering macrophage phenotype in prostate cancer
    Authors: A El-Kenawi, C Gatenbee, M Robertson-, R Bravo, J Dhillon, Y Balaguruna, A Berglund, N Visvakarma, A Ibrahim-Ha, J Choi, K Luddy, R Gatenby, S Pilon-Thom, A Anderson, B Ruffell, R Gillies
    Br. J. Cancer, 2019-08-16;121(7):556-566.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  171. Natural killer cells impede the engraftment of cardiomyocytes derived from induced pluripotent stem cells in syngeneic mouse model
    Authors: Y Nakamura, S Miyagawa, S Yoshida, S Sasawatari, T Toyofuku, K Toda, Y Sawa
    Sci Rep, 2019-07-25;9(1):10840.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  172. IL-22 Binding Protein Promotes the Disease Process in Multiple Sclerosis
    Authors: H Lindahl, AO Guerreiro-, SK Bedri, M Linnerbaue, M Lindén, N Abdelmagid, K Tandre, C Hollins, L Irving, C Glover, C Jones, L Alfredsson, L Rönnblom, I Kockum, M Khademi, M Jagodic, T Olsson
    J. Immunol., 2019-07-10;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  173. Nephropathy in Hypertensive Animals Is Linked to M2 Macrophages and Increased Expression of the YM1/Chi3l3 Protein
    Authors: PAM Cavalcante, N Alenina, A Budu, LC Freitas-Li, T Alves-Silv, JSH Agudelo, F Qadri, NOS Camara, M Bader, RC Araújo
    Mediators Inflamm., 2019-07-10;2019(0):9086758.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  174. Ammonia sensitive SLC4A11 mitochondrial uncoupling reduces glutamine induced oxidative stress
    Authors: DG Ogando, M Choi, R Shyam, S Li, JA Bonanno
    Redox Biol, 2019-06-23;26(0):101260.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  175. ATP6V0d2 controls Leishmania parasitophorous vacuole biogenesis via cholesterol homeostasis
    Authors: CC Pessoa, LC Reis, EM Ramos-Sanc, CM Orikaza, CC Plaza, EV de Castro, ACB Badaró, JUDS Yamamoto, V D'Almeida, H Goto, RA Mortara, F Real
    PLoS Pathog., 2019-06-14;15(6):e1007834.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  176. Tryptophan-related dipeptides in fermented dairy products suppress microglial activation and prevent cognitive decline
    Authors: Y Ano, Y Yoshino, T Kutsukake, R Ohya, T Fukuda, K Uchida, A Takashima, H Nakayama
    Aging (Albany NY), 2019-05-23;11(10):2949-2967.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  177. A Bcr-Abl Inhibitor GNF-2 Attenuates Inflammatory Activation of Glia and Chronic Pain
    Authors: GJ Song, MH Rahman, MK Jha, DP Gupta, SH Park, JH Kim, SH Lee, IK Lee, T Sim, YC Bae, WH Lee, K Suk
    Front Pharmacol, 2019-05-20;10(0):543.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  178. Newly defined ABCB5+ dermal mesenchymal stem cells promote healing of chronic iron overload wounds via secretion of interleukin-1 receptor antagonist
    Authors: S Vander Bek, JC de Vries, B Meier-Schi, P Meyer, D Jiang, A Sindrilaru, FF Ferreira, A Hainzl, S Schatz, J Muschhamme, NJ Scheurmann, P Kampilafko, AM Seitz, L Dürselen, A Ignatius, MA Kluth, C Ganss, M Wlaschek, K Singh, P Maity, NY Frank, MH Frank, K Scharffett
    Stem Cells, 2019-05-13;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  179. The Rho/MRTF pathway inhibitor CCG-222740 reduces stellate cell activation and modulates immune cell populations in KrasG12D; Pdx1-Cre (KC) mice
    Authors: AS Leal, SA Misek, EM Lisabeth, RR Neubig, KT Liby
    Sci Rep, 2019-05-08;9(1):7072.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  180. SIDT1 Localizes to Endolysosomes and Mediates Double-Stranded RNA Transport into the Cytoplasm
    Authors: TA Nguyen, BRC Smith, KD Elgass, SJ Creed, S Cheung, MD Tate, GT Belz, IP Wicks, SL Masters, KC Pang
    J. Immunol., 2019-05-06;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  181. Genetic Screen in Chlamydia muridarum Reveals Role for an Interferon-Induced Host Cell Death Program in Antimicrobial Inclusion Rupture
    Authors: AM Giebel, S Hu, K Rajaram, R Finethy, E Toh, JA Brothwell, SG Morrison, RJ Suchland, BD Stein, J Coers, RP Morrison, DE Nelson
    MBio, 2019-04-09;10(2):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  182. Signal regulatory protein ? protects podocytes through promoting autophagic activity
    Authors: L Li, Y Liu, S Li, Y Yang, C Zeng, W Rong, H Liang, M Zhang, X Zhu, K Kidder, Y Liu, Z Liu, K Zen
    JCI Insight, 2019-03-19;5(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  183. Siglec-15 as an immune suppressor and potential target for normalization cancer immunotherapy
    Authors: J Wang, J Sun, LN Liu, DB Flies, X Nie, M Toki, J Zhang, C Song, M Zarr, X Zhou, X Han, KA Archer, T O'Neill, RS Herbst, AN Boto, MF Sanmamed, S Langermann, DL Rimm, L Chen
    Nat. Med., 2019-03-04;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  184. Identification of P2Y receptors involved in oleamide-suppressing inflammatory responses in murine microglia and human dendritic cells
    Authors: M Kita, Y Ano, A Inoue, J Aoki
    Sci Rep, 2019-02-28;9(1):3135.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  185. Lactobacillus mucosae DPC 6426 as a bile-modifying and immunomodulatory microbe
    Authors: PM Ryan, EH Stolte, LEE London, JM Wells, SL Long, SA Joyce, CGM Gahan, GF Fitzgerald, RP Ross, NM Caplice, C Stanton
    BMC Microbiol., 2019-02-08;19(1):33.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  186. Memory-like Liver Natural Killer Cells are Responsible for Islet Destruction in Secondary Islet Transplantation
    Authors: Y Saeki, K Ishiyama, N Ishida, Y Tanaka, H Ohdan
    Sci Rep, 2019-01-31;9(1):1022.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  187. Theaflavins Improve Memory Impairment and Depression-Like Behavior by Regulating Microglial Activation
    Authors: Y Ano, R Ohya, M Kita, Y Taniguchi, K Kondo
    Molecules, 2019-01-28;24(3):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  188. Vitamin D improves sunburns by increasing autophagy in M2 macrophages
    Authors: LM Das, AM Binko, ZP Traylor, H Peng, KQ Lu
    Autophagy, 2019-01-24;0(0):1-14.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  189. Resolution of Cutaneous Leishmaniasis and Persistence of Leishmania major in the Absence of Arginase 1
    Authors: K Paduch, A Debus, B Rai, U Schleicher, C Bogdan
    J. Immunol., 2019-01-21;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  190. Myeloid Slc2a1-Deficient Murine Model Revealed Macrophage Activation and Metabolic Phenotype Are Fueled by GLUT1
    Authors: AJ Freemerman, L Zhao, AK Pingili, B Teng, AJ Cozzo, AM Fuller, AR Johnson, JJ Milner, MF Lim, JA Galanko, MA Beck, JE Bear, JD Rotty, L Bezavada, HS Smallwood, MA Puchowicz, J Liu, JW Locasale, DP Lee, BJ Bennett, ED Abel, JC Rathmell, L Makowski
    J. Immunol., 2019-01-18;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
  191. MUC16 suppresses human and murine innate immune responses
    Authors: M Felder, A Kapur, AL Rakhmilevi, X Qu, PM Sondel, SD Gillies, J Connor, MS Patankar
    Gynecol. Oncol., 2019-01-06;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  192. Trabectedin Reduces Skeletal Prostate Cancer Tumor Size in Association with Effects on M2 Macrophages and Efferocytosis
    Authors: JD Jones, BP Sinder, D Paige, FN Soki, AJ Koh, S Thiele, Y Shiozawa, LC Hofbauer, S Daignault, H Roca, LK McCauley
    Neoplasia, 2018-12-31;21(2):172-184.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  193. REV-ERB? Regulates TH17 Cell Development and Autoimmunity
    Authors: M Amir, S Chaudhari, R Wang, S Campbell, SA Mosure, LB Chopp, Q Lu, J Shang, OB Pelletier, Y He, C Doebelin, MD Cameron, DJ Kojetin, TM Kamenecka, LA Solt
    Cell Rep, 2018-12-26;25(13):3733-3749.e8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  194. BCL6-Mediated Silencing of PD-1 Ligands in Germinal Center B Cells Maintains Follicular T Cell Population
    Authors: C Peng, Q Hu, F Yang, H Zhang, F Li, C Huang
    J. Immunol., 2018-12-19;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  195. EriB targeted inhibition of microglia activity attenuates MPP+ induced DA neuron injury through the NF-?B signaling pathway
    Authors: F Dou, X Chu, B Zhang, L Liang, G Lu, J Ding, S Chen
    Mol Brain, 2018-12-18;11(1):75.
    Species: Mouse
    Sample Types: Recombinant Protein
    Applications: ELISA (Standard)
  196. AMPK Activation Regulates LTBP4-Dependent TGF-?1 Secretion by Pro-inflammatory Macrophages and Controls Fibrosis in Duchenne Muscular Dystrophy
    Authors: G Juban, M Saclier, H Yacoub-You, A Kernou, L Arnold, C Boisson, S Ben Larbi, M Magnan, S Cuvellier, M Théret, BJ Petrof, I Desguerre, J Gondin, R Mounier, B Chazaud
    Cell Rep, 2018-11-20;25(8):2163-2176.e6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  197. Weighted Gene Correlation Network Analysis (WGCNA) Detected Loss of MAGI2 Promotes Chronic Kidney Disease (CKD) by Podocyte Damage
    Authors: Z Zuo, JX Shen, Y Pan, J Pu, YG Li, XH Shao, WP Wang
    Cell. Physiol. Biochem., 2018-11-16;51(1):244-261.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  198. Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis
    Authors: AM Falcão, D van Brugge, S Marques, M Meijer, S Jäkel, E Agirre, Samudyata, EM Floriddia, DP Vanichkina, C Ffrench-Co, A Williams, AO Guerreiro-, G Castelo-Br
    Nat. Med., 2018-11-12;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  199. Cyp1b1 expression impacts the angiogenic and inflammatory properties of liver sinusoidal endothelial cells
    Authors: J Falero-Per, YS Song, Y Zhao, L Teixeira, CM Sorenson, N Sheibani
    PLoS ONE, 2018-10-29;13(10):e0206756.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  200. Protection against Staphylococcus aureus Colonization and Infection by B- and T-Cell-Mediated Mechanisms
    Authors: F Zhang, O Ledue, M Jun, C Goulart, R Malley, YJ Lu
    MBio, 2018-10-16;9(5):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  201. Innate and adaptive signals enhance differentiation and expansion of dual-antibody autoreactive B cells in lupus
    Authors: A Sang, T Danhorn, JN Peterson, AL Rankin, BP O'Connor, SM Leach, RM Torres, R Pelanda
    Nat Commun, 2018-09-28;9(1):3973.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  202. Astaxanthin exerts anti-inflammatory and antioxidant effects in macrophages in NRF2-dependent and independent manners
    Authors: C Farruggia, MB Kim, M Bae, Y Lee, TX Pham, Y Yang, MJ Han, YK Park, JY Lee
    J. Nutr. Biochem., 2018-09-19;62(0):202-209.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  203. Glucosylceramide modifies the LPS-induced inflammatory response in macrophages and the orientation of the LPS/TLR4 complex in silico
    Authors: E Mobarak, L Håversen, M Manna, M Rutberg, M Levin, R Perkins, T Rog, I Vattulaine, J Borén
    Sci Rep, 2018-09-11;8(1):13600.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  204. Plectin protects podocytes from adriamycin-induced apoptosis and F-actin cytoskeletal disruption through the integrin ?6?4/FAK/p38 MAPK pathway
    Authors: Y Ni, X Wang, X Yin, Y Li, X Liu, H Wang, X Liu, J Zhang, H Gao, B Shi, S Zhao
    J. Cell. Mol. Med., 2018-09-06;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  205. Interferon-gamma inhibits seminal plasma induction of colony stimulating factor 2 in mouse and human reproductive tract epithelial cells
    Authors: DJ Sharkey, DJ Glynn, JE Schjenken, KP Tremellen, SA Robertson
    Biol. Reprod., 2018-09-01;0(0):.
    Species: Mouse
    Sample Types: In Vivo, Whole Cells
    Applications: Bioassay, In Vivo
  206. Roles of Exosome-Like Vesicles Released from Inflammatory C2C12 Myotubes: Regulation of Myocyte Differentiation and Myokine Expression
    Authors: S Kim, MJ Lee, JY Choi, DH Park, HB Kwak, S Moon, JW Koh, HK Shin, JK Ryu, CS Park, JH Park, JH Kang
    Cell. Physiol. Biochem., 2018-08-09;48(5):1829-1842.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Stimulation
  207. Role of IL-18 induced Amphiregulin expression on virus induced ocular lesions
    Authors: SK Varanasi, NK Rajasagi, U Jaggi, BT Rouse
    Mucosal Immunol, 2018-08-07;0(0):.
    Species: Mouse
    Sample Types:
  208. Human umbilical cord-derived mesenchymal stem cells direct macrophage polarization to alleviate pancreatic islets dysfunction in type 2 diabetic mice
    Authors: Y Yin, H Hao, Y Cheng, L Zang, J Liu, J Gao, J Xue, Z Xie, Q Zhang, W Han, Y Mu
    Cell Death Dis, 2018-07-09;9(7):760.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  209. The AMPK agonist 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR), but not metformin, prevents inflammation-associated cachectic muscle wasting
    Authors: DT Hall, T Griss, JF Ma, BJ Sanchez, J Sadek, AMK Tremblay, S Mubaid, A Omer, RJ Ford, N Bedard, A Pause, SS Wing, S Di Marco, GR Steinberg, RG Jones, IE Gallouzi
    EMBO Mol Med, 2018-07-01;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  210. Parasitic helminths induce fetal-like reversion in the intestinal stem cell niche
    Authors: YM Nusse, AK Savage, P Marangoni, AKM Rosendahl-, TA Landman, FJ de Sauvage, RM Locksley, OD Klein
    Nature, 2018-06-27;559(7712):109-113.
    Species: Mouse
    Sample Types: Organoids
    Applications: Bioassay
  211. Tumor-derived granzyme B-expressing neutrophils acquire antitumor potential after lipid A treatment.
    Authors: A Martin, C Seignez, C Racoeur, N Isambert, Isambert N, N Mabrouk, Mabrouk N, A Scagliarin, Scagliarini A, S Reveneau, Reveneau S, L Arnould, Arnould L, A Bettaieb, JF Jeannin, Jeannin J, C Paul
    Oncotarget, 2018-06-19;9(47):28364-28378.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  212. eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways
    Authors: Z Cramer, J Sadek, GG Vazquez, S Di Marco, A Pause, J Pelletier, IE Gallouzi
    Sci Rep, 2018-05-30;8(1):8414.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  213. Total Flavonoids from Radix Glycyrrhiza Exert Anti-Inflammatory and Antitumorigenic Effects by Inactivating iNOS Signaling Pathways
    Authors: YX Jiang, YY Dai, YF Pan, XM Wu, Y Yang, K Bian, DD Zhang
    Evid Based Complement Alternat Med, 2018-05-22;2018(0):6714282.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  214. Mycobacterium tuberculosis PPE60 antigen drives Th1/Th17 responses via Toll-like receptor 2-dependent maturation of dendritic cells
    Authors: H Su, Z Zhang, Z Liu, B Peng, C Kong, H Wang, Z Zhang, Y Xu
    J. Biol. Chem., 2018-05-08;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  215. Reduction of MHC-I expression limits T-lymphocyte-mediated killing of Cancer-initiating cells
    Authors: BJ Morrison, JC Steel, JC Morris
    BMC Cancer, 2018-04-26;18(1):469.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  216. A Nonpyroptotic IFN-?-Triggered Cell Death Mechanism in Nonphagocytic Cells Promotes Salmonella Clearance In Vivo
    Authors: JP Ingram, S Tursi, T Zhang, W Guo, C Yin, M A Wynosky-, J van der He, KQ Cai, M Yamamoto, BB Finlay, IE Brodsky, SI Grivenniko, Ç Tükel, S Balachandr
    J. Immunol., 2018-04-13;0(0):.
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  217. Loss of NF-?B1 Causes Gastric Cancer with Aberrant Inflammation and Expression of Immune Checkpoint Regulators in a STAT-1-Dependent Manner
    Authors: LA O'Reilly, TL Putoczki, LA Mielke, JT Low, A Lin, A Preaudet, MJ Herold, K Yaprianto, L Tai, A Kueh, G Pacini, RL Ferrero, R Gugasyan, Y Hu, M Christie, S Wilcox, R Grumont, MDW Griffin, L O'Connor, GK Smyth, M Ernst, P Waring, S Gerondakis, A Strasser
    Immunity, 2018-03-20;48(3):570-583.e8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  218. Induced pluripotent stem cells-derived myeloid-derived suppressor cells regulate the CD8+ T cell response
    Authors: D Joyce, M Fujino, M Morita, R Araki, J Fung, S Qian, L Lu, XK Li
    Stem Cell Res, 2018-03-16;29(0):32-41.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  219. The deficiency of CX3CL1/CX3CR1 system ameliorates high fructose diet-induced kidney injury by regulating NF-κB pathways in CX3CR1-knock out mice
    Authors: YW Yu, MX Li, ZY Zhang, H Yu
    Int. J. Mol. Med., 2018-03-16;41(6):3577-3585.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  220. Tetrahydrocurcumin Enhances Islet Cell Function and Attenuates Apoptosis in Mouse Islets
    Authors: SS Kim, HJ Jang, MY Oh, JH Lee, KS Kang
    Transplant. Proc., 2018-03-16;50(9):2847-2853.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  221. Tumor-Repopulating Cells Induce PD-1 Expression in CD8+T Cells by Transferring Kynurenine and AhR Activation
    Authors: Y Liu, X Liang, W Dong, Y Fang, J Lv, T Zhang, R Fiskesund, J Xie, J Liu, X Yin, X Jin, D Chen, K Tang, J Ma, H Zhang, J Yu, J Yan, H Liang, S Mo, F Cheng, Y Zhou, H Zhang, J Wang, J Li, Y Chen, B Cui, ZW Hu, X Cao, F Xiao-Feng, B Huang
    Cancer Cell, 2018-03-12;33(3):480-494.e7.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  222. RGC32 Promotes Bleomycin-Induced Systemic Sclerosis in a Murine Disease Model by Modulating Classically Activated Macrophage Function
    Authors: C Sun, SY Chen
    J. Immunol., 2018-03-05;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  223. A20 upregulation during treated HIV disease is associated with intestinal epithelial cell recovery and function
    Authors: AS Chitre, MG Kattah, YY Rosli, M Pao, M Deswal, SG Deeks, PW Hunt, M Abdel-Mohs, LJ Montaner, CC Kim, A Ma, M Somsouk, JM McCune
    PLoS Pathog., 2018-03-05;14(3):e1006806.
    Species: Mouse
    Sample Types: Organoids
    Applications: Bioassay
  224. Mesenchymal stem cells ameliorate experimental arthritis via expression of interleukin-1 receptor antagonist
    Authors: K Lee, N Park, H Jung, YA Rim, Y Nam, J Lee, SH Park, JH Ju
    PLoS ONE, 2018-02-26;13(2):e0193086.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  225. GPR142 prompts glucagon-like Peptide-1 release from islets to improve ? cell function
    Authors: HV Lin, J Wang, J Wang, W Li, X Wang, JT Alston, MK Thomas, DA Briere, SK Syed, AM Efanov
    Mol Metab, 2018-02-23;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  226. SOCS3 deficiency in myeloid cells promotes retinal degeneration and angiogenesis through arginase-1 up-regulation in experimental autoimmune uveoretinitis
    Authors: M Chen, J Zhao, IH Ali, S Marry, J Augustine, M Bhuckory, A Lynch, A Kissenpfen, H Xu
    Am. J. Pathol., 2018-02-13;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  227. In vitro evaluation of the anti-leishmanial activity and toxicity of PK11195
    Authors: CES Guedes, BRS Dias, ALOA Petersen, KP Cruz, NJ Almeida, DR Andrade, JPB Menezes, VM Borges, PST Veras
    Mem. Inst. Oswaldo Cruz, 2018-02-05;113(4):e170345.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  228. Collagen-derived peptides modulate CD4T-cell differentiation and suppress allergic responses in mice
    Authors: A Nishikimi, YI Koyama, S Ishihara, S Kobayashi, C Tometsuka, M Kusubata, K Kuwaba, O Hayashida, S Hattori, K Katagiri
    Immun Inflamm Dis, 2018-02-01;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  229. Circular RNAs as novel regulators of ?-cell functions in normal and disease conditions
    Authors: L Stoll, J Sobel, A Rodriguez-, C Guay, K Lee, MT Venø, J Kjems, DR Laybutt, R Regazzi
    Mol Metab, 2018-01-31;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  230. High-Resolution Mapping and Dynamics of the Transcriptome, Transcription Factors, and Transcription Co-Factor Networks in Classically and Alternatively Activated Macrophages
    Authors: A Das, CS Yang, S Arifuzzama, S Kim, SY Kim, KH Jung, YS Lee, YG Chai
    Front Immunol, 2018-01-18;9(0):22.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  231. Loss of Paneth Cell Autophagy Causes Acute Susceptibility to Toxoplasma gondii-Mediated Inflammation
    Authors: E Burger, A Araujo, A López-Ygle, MW Rajala, L Geng, B Levine, LV Hooper, E Burstein, F Yarovinsky
    Cell Host Microbe, 2018-01-18;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Stimulation
  232. PGC-1? ameliorates kidney fibrosis in mice with diabetic kidney disease through an antioxidative mechanism
    Authors: L Zhang, J Liu, F Zhou, W Wang, N Chen
    Mol Med Rep, 2018-01-16;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  233. PEDF Expression Affects the Oxidative and Inflammatory State of Choroidal Endothelial Cells
    Authors: M Farnoodian, CM Sorenson, N Sheibani
    Am. J. Physiol., Cell Physiol., 2018-01-10;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  234. Microglial activation and the nitric oxide/cGMP/PKG pathway underlie enhanced neuronal vulnerability to mitochondrial dysfunction in experimental multiple sclerosis
    Authors: A Mancini, M Tantucci, P Mazzocchet, A de Iure, V Durante, L Macchioni, C Giampà, A Alvino, L Gaetani, C Costa, A Tozzi, P Calabresi, M Di Filippo
    Neurobiol. Dis., 2018-01-09;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  235. Human papillomavirus E7 oncoprotein expression by keratinocytes alters the cytotoxic mechanisms used by CD8 T cells
    Authors: P Bhat, AS Bergot, N Waterhouse, IH Frazer
    Oncotarget, 2017-12-14;9(5):6015-6027.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  236. Extracellular Lactate Dehydrogenase A Release From Damaged Neurons Drives Central Nervous System Angiogenesis
    Authors: H Lin, R Muramatsu, N Maedera, H Tsunematsu, M Hamaguchi, Y Koyama, M Kuroda, K Ono, M Sawada, T Yamashita
    EBioMedicine, 2017-12-07;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  237. Liraglutide dictates macrophage phenotype in apolipoprotein E null mice during early atherosclerosis
    Authors: R Bruen, S Curley, S Kajani, D Crean, ME O'Reilly, MB Lucitt, CG Godson, FC McGillicud, O Belton
    Cardiovasc Diabetol, 2017-11-06;16(1):143.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  238. The histone deacetylase SIRT6 blocks myostatin expression and development of muscle atrophy
    Authors: SA Samant, A Kanwal, VB Pillai, R Bao, MP Gupta
    Sci Rep, 2017-09-19;7(1):11877.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  239. Dormant 5-lipoxygenase in inflammatory macrophages is triggered by exogenous arachidonic acid
    Authors: CA Sorgi, S Zarini, SA Martin, RL Sanchez, RF Scandiuzzi, MA Gijón, C Guijas, N Flamand, RC Murphy, LH Faccioli
    Sci Rep, 2017-09-08;7(1):10981.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  240. Interleukin 4 receptor-targeted pro-apoptotic peptide blocks tumor growth and metastasis by enhancing anti-tumor immunity
    Authors: SMP Vadevoo, JE Kim, GR Gunassekar, HK Jung, L Chi, DE Kim, SH Lee, SH Im, B Lee
    Mol. Cancer Ther., 2017-09-06;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  241. Co-encapsulation and co-transplantation of mesenchymal stem cells reduces pericapsular fibrosis and improves encapsulated islet survival and function when allografted
    Authors: V Vaithiling, MDM Evans, DM Lewy, PA Bean, S Bal, BE Tuch
    Sci Rep, 2017-08-30;7(1):10059.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  242. Nitric Oxide Modulates Macrophage Responses to Mycobacterium tuberculosis Infection through Activation of HIF-1? and Repression of NF-?B
    Authors: J Braverman, SA Stanley
    J. Immunol., 2017-07-28;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  243. Modulation of Roquin Function in Myeloid Cells Reduces Mycobacterium tuberculosis-Induced Inflammation
    Authors: G Nagalingam, CG Vinuesa, WJ Britton, BM Saunders
    J. Immunol., 2017-07-26;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  244. TRIM21 is critical for survival of Toxoplasma gondii infection and localises to GBP-positive parasite vacuoles
    Authors: C Foltz, A Napolitano, R Khan, B Clough, EM Hirst, EM Frickel
    Sci Rep, 2017-07-12;7(1):5209.
    Species: Human, Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  245. Pancreatic ?-cell protection from inflammatory stress by the endoplasmic reticulum proteins thrombospondin 1 and mesencephalic astrocyte-derived neutrotrophic factor (MANF)
    Authors: DA Cunha, M Cito, FA Grieco, C Cosentino, T Danilova, L Ladriere, M Lindahl, A Domanskyi, M Bugliani, P Marchetti, DL Eizirik, M Cnop
    J. Biol. Chem., 2017-07-11;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  246. The PSMP-CCR2 interactions trigger monocyte/macrophage-dependent colitis
    Authors: X Pei, D Zheng, S She, J Ma, C Guo, X Mo, Y Zhang, Q Song, Y Zhang, D Ma, Y Wang
    Sci Rep, 2017-07-11;7(1):5107.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  247. Conditionally Immortal Slc4a11-/- Mouse Corneal Endothelial Cell Line Recapitulates Disrupted Glutaminolysis Seen in Slc4a11-/- Mouse Model
    Authors: W Zhang, DG Ogando, ET Kim, MJ Choi, H Li, JM Tenessen, JA Bonanno
    Invest. Ophthalmol. Vis. Sci., 2017-07-01;58(9):3723-3731.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  248. CD4(+)CD8?(+) double-positive T cells in skin-draining lymph nodes respond to inflammatory signals from the skin
    Authors: NH Overgaard, JL Cruz, JA Bridge, HJ Nel, IH Frazer, NL La Gruta, A Blumenthal, RJ Steptoe, JW Wells
    J. Leukoc. Biol., 2017-06-21;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  249. The inhibition of NLRP3 signaling attenuates liver injury in an ?-galactosylceramide-induced hepatitis model
    Authors: A Kanbe, H Ito, Y Omori, A Hara, M Seishima
    Biochem. Biophys. Res. Commun., 2017-06-14;0(0):.
    Applications: ELISA (Standard)
  250. The Transcription Factor T-bet Limits Amplification of Type I IFN Transcriptome and Circuitry in T Helper 1 Cells
    Authors: S Iwata, Y Mikami, HW Sun, SR Brooks, D Jankovic, K Hirahara, A Onodera, HY Shih, T Kawabe, K Jiang, T Nakayama, A Sher, JJ O'Shea, FP Davis, Y Kanno
    Immunity, 2017-06-13;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  251. Interferon-? derived from cytotoxic lymphocytes directly enhances their motility and cytotoxicity
    Authors: P Bhat, G Leggatt, N Waterhouse, IH Frazer
    Cell Death Dis, 2017-06-01;8(6):e2836.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  252. KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington's disease patients
    Authors: L Quinti, S Dayalan Na, U Träger, X Chen, K Kegel-Glea, D Llères, C Connolly, V Chopra, C Low, S Moniot, E Sapp, AR Tousley, P Vodicka, MJ Van Kanega, LS Kaltenbach, LA Crawford, M Fuszard, M Higgins, JRC Miller, RE Farmer, V Potluri, S Samajdar, L Meisel, N Zhang, A Snyder, R Stein, SM Hersch, LM Ellerby, E Weerapana, MA Schwarzsch, C Steegborn, BR Leavitt, A Degterev, SJ Tabrizi, DC Lo, M DiFiglia, LM Thompson, AT Dinkova-Ko, AG Kazantsev
    Proc. Natl. Acad. Sci. U.S.A., 2017-05-22;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  253. Prolactin blocks the expression of receptor activator of nuclear factor ?B ligand and reduces osteoclastogenesis and bone loss in murine inflammatory arthritis
    Authors: MG Ledesma-Co, N Adán, G Ortiz, M Solís-Guti, F López-Barr, G Martínez d, C Clapp
    Arthritis Res. Ther., 2017-05-15;19(1):93.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  254. A Rab20-Dependent Membrane Trafficking Pathway Controls M.�tuberculosis Replication by Regulating Phagosome Spaciousness and Integrity
    Authors: L Schnettger, A Rodgers, U Repnik, RP Lai, G Pei, M Verdoes, RJ Wilkinson, DB Young, MG Gutierrez
    Cell Host Microbe, 2017-05-10;21(5):619-628.e5.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  255. STAT3 promotes IFN?/TNF?-induced muscle wasting in an NF-?B-dependent and IL-6-independent manner
    Authors: JF Ma, BJ Sanchez, DT Hall, AK Tremblay, S Di Marco, IE Gallouzi
    EMBO Mol Med, 2017-05-01;0(0):.
    Species: Mouse
    Sample Types: In Vivo, Whole Cells
    Applications: Bioassay, In Vivo
  256. IL-10 down-regulates the expression of survival associated gene hspX of Mycobacterium tuberculosis in murine macrophage
    Authors: B Jee, P Sharma, K Katoch, B Joshi, SK Awasthi
    Braz J Infect Dis, 2017-04-20;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  257. CD11b regulates antibody class switching via induction of AID
    Authors: S Park, H Sim, HI Kim, D Jeong, G Wu, SY Cho, YS Lee, HJ Kwon, K Lee
    Mol. Immunol., 2017-04-11;87(0):47-59.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  258. Microglia activation is essential for BMP7-mediated retinal reactive gliosis
    Authors: S Dharmaraja, DL Fisk, CM Sorenson, N Sheibani, TL Belecky-Ad
    J Neuroinflammation, 2017-04-05;14(1):76.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  259. IL-33 contributes to sepsis-induced long-term immunosuppression by expanding the regulatory T cell population
    Authors: DC Nascimento, PH Melo, AR Piñeros, RG Ferreira, DF Colón, PB Donate, FV Castanheir, A Gozzi, PG Czaikoski, W Niedbala, MC Borges, DS Zamboni, FY Liew, FQ Cunha, JC Alves-Filh
    Nat Commun, 2017-04-04;8(0):14919.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  260. A type I IFN-dependent DNA damage response regulates the genetic program and inflammasome activation in macrophages
    Authors: AJ Morales, JA Carrero, PJ Hung, AT Tubbs, JM Andrews, BT Edelson, B Calderon, CL Innes, RS Paules, JE Payton, BP Sleckman
    Elife, 2017-03-31;6(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  261. Opposing macrophage polarization programs show extensive epigenomic and transcriptional cross-talk
    Authors: V Piccolo, A Curina, M Genua, S Ghisletti, M Simonatto, A Sabò, B Amati, R Ostuni, G Natoli
    Nat. Immunol, 2017-03-13;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  262. The Shc1 adaptor simultaneously balances Stat1 and Stat3 activity to promote breast cancer immune suppression
    Authors: R Ahn, V Sabourin, AM Bolt, S Hébert, S Totten, N De Jay, MC Festa, YK Young, YK Im, T Pawson, AE Koromilas, WJ Muller, KK Mann, CL Kleinman, J Ursini-Sie
    Nat Commun, 2017-03-09;8(0):14638.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  263. Robust growth of avirulent phase II Coxiella burnetii in bone marrow-derived murine macrophages
    Authors: DC Cockrell, CM Long, SJ Robertson, JG Shannon, HE Miller, L Myers, CL Larson, T Starr, PA Beare, RA Heinzen
    PLoS ONE, 2017-03-09;12(3):e0173528.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  264. MicroRNA-27a promotes podocyte injury via PPAR?-mediated ?-catenin activation in diabetic nephropathy
    Authors: Z Zhou, J Wan, X Hou, J Geng, X Li, X Bai
    Cell Death Dis, 2017-03-09;8(3):e2658.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  265. Role of pterostilbene in attenuating immune mediated devastation of pancreatic beta cells via Nrf2 signaling cascade
    Authors: D Sireesh, MR Ganesh, U Dhamodhara, M Sakthivadi, S Sivasubram, P Gunasekara, KM Ramkumar
    J. Nutr. Biochem, 2017-03-06;44(0):11-21.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  266. Characterisation of iunH gene knockout strain from Mycobacterium tuberculosis
    Authors: AD Villela, VD Rodrigues, AF Pinto, PL Wink, ZA Sánchez-Qu, GO Petersen, MM Campos, LA Basso, DS Santos
    Mem. Inst. Oswaldo Cruz, 2017-03-01;112(3):203-208.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  267. HMGB1 is upregulated in the airways in asthma and potentiates airway smooth muscle contraction via TLR4
    Authors: L Di Candia, E Gomez, E Venereau, L Chachi, D Kaur, ME Bianchi, RA Challiss, CE Brightling, RM Saunders
    J. Allergy Clin. Immunol, 2017-03-01;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  268. Metabolic origins of spatial organization in the tumor microenvironment
    Authors: C Carmona-Fo, M Deforet, L Akkari, CB Thompson, JA Joyce, JB Xavier
    Proc. Natl. Acad. Sci. U.S.A, 2017-02-28;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  269. Mesenchymal stem cells in alleviating sepsis-induced mice cardiac dysfunction via inhibition of mTORC1-p70S6K signal pathway
    Authors: W Huang, W Fan, Y Wang, D Han, X Li, S Li, C Li, B Xu, Y Huang, X Fu, F Cao
    Cell Death Discov, 2017-02-27;3(0):16097.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  270. Tumour and host cell PD-L1 is required to mediate suppression of anti-tumour immunity in mice
    Authors: J Lau, J Cheung, A Navarro, S Lianoglou, B Haley, K Totpal, L Sanders, H Koeppen, P Caplazi, J McBride, H Chiu, R Hong, J Grogan, V Javinal, R Yauch, B Irving, M Belvin, I Mellman, JM Kim, M Schmidt
    Nat Commun, 2017-02-21;8(0):14572.
    Species: Mouse
    Sample Types: Cell Culture Supernates
    Applications: Bioassay
  271. PEDF mediates pathological neovascularization by regulating macrophage recruitment and polarization in the mouse model of oxygen-induced retinopathy
    Authors: S Gao, C Li, Y Zhu, Y Wang, A Sui, Y Zhong, B Xie, X Shen
    Sci Rep, 2017-02-17;7(0):42846.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  272. Gut memories do not fade: epigenetic regulation of lasting gut homing receptor expression in CD4(+) memory T cells
    Authors: BA Szilagyi, J Triebus, C Kressler, M de Almeida, S Tierling, P Durek, M Mardahl, A Szilagyi, S Floess, J Huehn, U Syrbe, J Walter, JK Polansky, A Hamann
    Mucosal Immunol, 2017-02-15;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  273. Astrocytic orosomucoid-2 modulates microglial activation and neuroinflammation
    Authors: M Jo, JH Kim, G Song, M Seo, E Mi Hwang, K Suk
    J. Neurosci, 2017-02-13;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  274. Pathogen-mediated manipulation of arthropod microbiota to promote infection
    Authors: NM Abraham, L Liu, BL Jutras, AK Yadav, S Narasimhan, V Gopalakris, JM Ansari, KK Jefferson, F Cava, C Jacobs-Wag, E Fikrig
    Proc. Natl. Acad. Sci. U.S.A, 2017-01-17;114(5):E781-E790.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  275. Dual role of ALCAM in neuroinflammation and blood-brain barrier homeostasis
    Authors: MA L‚cuyer, O Saint-Laur, L BourbonniŠ, S Larouche, C Larochelle, L Michel, M Charabati, M Abadier, S Zandee, N Haghayegh, E Gowing, C Pittet, R Lyck, B Engelhardt, A Prat
    Proc. Natl. Acad. Sci. U.S.A, 2017-01-09;114(4):E524-E533.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  276. Th1 cells downregulate connexin 43 gap junctions in astrocytes via microglial activation
    Sci Rep, 2016-12-08;6(0):38387.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  277. Context-Specific and Immune Cell-Dependent Antitumor Activities of ?1-Antitrypsin
    Authors: Ofer Guttman
    Front Immunol, 2016-12-07;7(0):559.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  278. Biomimetic biodegradable artificial antigen presenting cells synergize with PD-1 blockade to treat melanoma
    Authors: A K Kosmides
    Biomaterials, 2016-12-02;118(0):16-26.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  279. Pharmacologic modulation of ROR?t translates to efficacy in preclinical and translational models of psoriasis and inflammatory arthritis
    Sci Rep, 2016-12-01;6(0):37977.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  280. Application of genetically engineered Salmonella typhimurium for interferon-gamma-induced therapy against melanoma
    Authors: Byeong Mo Kim
    Eur. J. Cancer, 2016-11-22;70(0):48-61.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  281. Epobis is a Nonerythropoietic and Neuroprotective Agonist of the Erythropoietin Receptor with Anti-Inflammatory and Memory Enhancing Effects
    Authors: Oksana Dmytriyeva
    Mediators Inflamm, 2016-11-21;2016(0):1346390.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  282. Individual and interactive sex-specific effects of acute restraint and systemic IFN-? treatment on neurochemistry
    Authors: Shawn Hayley
    Neurochem. Int., 2016-11-19;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  283. Roles of endoplasmic reticulum stress-mediated apoptosis in M1-polarized macrophages during mycobacterial infections
    Sci Rep, 2016-11-15;6(0):37211.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  284. Macrophages form functional vascular mimicry channels in vivo
    Sci Rep, 2016-11-11;6(0):36659.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  285. Identification and Function of Fibrocytes in Skeletal Muscle Injury Repair and Muscular Dystrophy
    J. Immunol., 2016-11-09;197(12):4750-4761.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  286. Therapeutic reversal of food allergen sensitivity by mature retinoic acid-differentiated dendritic cell induction of LAG3(+)CD49b(-)Foxp3(-) regulatory T�cells
    Authors: W Dawicki, C Li, J Town, X Zhang, JR Gordon
    J. Allergy Clin. Immunol., 2016-10-26;139(5):1608-1620.e3.
    Species: Mouse
    Sample Types: Serum
    Applications: ELISA (Standard)
  287. Proteasome Activators, PA28? and PA28?, Govern Development of Microvascular Injury in Diabetic Nephropathy and Retinopathy
    Authors: Ali Mahmoudpou
    Int J Nephrol, 2016-10-18;2016(0):3846573.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  288. Tumor-intrinsic PD-L1 signals regulate cell growth, pathogenesis and autophagy in ovarian cancer and melanoma
    Cancer Res, 2016-09-26;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  289. Polarization of macrophages towards M2 phenotype is favored by reduction in iPLA2?
    J Biol Chem, 2016-09-20;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  290. Lack of immunoediting in murine pancreatic cancer reversed with neoantigen
    JCI Insight, 2016-09-08;1(14):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  291. Mechanisms Underlying Interferon-?-Induced Priming of Microglial Reactive Oxygen Species Production
    PLoS ONE, 2016-09-06;11(9):e0162497.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  292. Mp1p Is a Virulence Factor in Talaromyces (Penicillium) marneffei
    PLoS Negl Trop Dis, 2016-08-25;10(8):e0004907.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  293. Dimethyl fumarate alters microglia phenotype and protects neurons against proinflammatory toxic microenvironments
    Authors: Haiyan Peng
    J. Neuroimmunol, 2016-08-05;299(0):35-44.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  294. NADPH oxidases are essential for macrophage differentiation
    J Biol Chem, 2016-08-03;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  295. Early infiltration of p40IL12(+)CCR7(+)CD11b(+) cells is critical for fibrosis development
    Authors: Niels Olsen Saraiva Camara
    Immun Inflamm Dis, 2016-07-21;4(3):300-14.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  296. HIF-1? Is an Essential Mediator of IFN-?-Dependent Immunity to Mycobacterium tuberculosis
    J Immunol, 2016-07-18;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  297. Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status
    Circ Res, 2016-07-14;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  298. G2A Signaling Dampens Colitic Inflammation via Production of IFN-?
    J Immunol, 2016-07-08;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  299. Mycobacterium leprae-induced Insulin-like Growth Factor I attenuates antimicrobial mechanisms, promoting bacterial survival in macrophages
    Authors: L R Batista-Si
    Sci Rep, 2016-06-10;6(0):27632.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  300. Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription
    Nat Commun, 2016-05-23;7(0):11624.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  301. Attenuation of PKR-like ER Kinase (PERK) Signaling Selectively Controls Endoplasmic Reticulum Stress-induced Inflammation Without Compromising Immunological Responses
    Authors: LN Guthrie, K Abiraman, ES Plyler, NT Sprenkle, SA Gibson, BC McFarland, R Rajbhandar, AL Rowse, EN Benveniste, GP Meares
    J. Biol. Chem., 2016-05-23;291(30):15830-40.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  302. Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor
    Nat Med, 2016-05-09;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  303. Platelets Guide Leukocytes to Their Sites of Extravasation
    PLoS Biol, 2016-05-06;14(5):e1002459.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  304. Elastin-Derived Peptides Promote Abdominal Aortic Aneurysm Formation by Modulating M1/M2 Macrophage Polarization
    J Immunol, 2016-05-04;196(11):4536-43.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  305. Type I interferons exert anti-tumor effect via reversing immunosuppression mediated by mesenchymal stromal cells
    Authors: P Shou, Q Chen, J Jiang, C Xu, J Zhang, C Zheng, M Jiang, T Velletri, W Cao, Y Huang, Q Yang, X Han, L Zhang, L Wei, AB Rabson, YE Chin, Y Wang, Y Shi
    Oncogene, 2016-04-25;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  306. Conditioned Medium from the Stem Cells of Human Exfoliated Deciduous Teeth Ameliorates Experimental Autoimmune Encephalomyelitis
    Authors: C Shimojima, H Takeuchi, S Jin, B Parajuli, H Hattori, A Suzumura, H Hibi, M Ueda, A Yamamoto
    J Immunol, 2016-04-06;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  307. Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9.
    Authors: Doench J, Fusi N, Sullender M, Hegde M, Vaimberg E, Donovan K, Smith I, Tothova Z, Wilen C, Orchard R, Virgin H, Listgarten J, Root D
    Nat Biotechnol, 2016-01-18;34(2):184-91.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  308. Anti-Tumor and Immune Enhancing Activities of Rice Bran Gramisterol on Acute Myelogenous Leukemia.
    Authors: Somintara S, Leardkamolkarn V, Suttiarporn P, Mahatheeranont S
    PLoS ONE, 2016-01-11;11(1):e0146869.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  309. TRIM38 Negatively Regulates TLR3/4-Mediated Innate Immune and Inflammatory Responses by Two Sequential and Distinct Mechanisms.
    Authors: Hu M, Xie X, Yang Q, Liao C, Ye W, Lin H, Shu H
    J Immunol, 2015-09-21;195(9):4415-25.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  310. IFN-gamma Prevents Adenosine Receptor (A2bR) Upregulation To Sustain the Macrophage Activation Response.
    Authors: Cohen H, Ward A, Hamidzadeh K, Ravid K, Mosser D
    J Immunol, 2015-09-09;195(8):3828-37.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  311. Effector T Cell Egress via Afferent Lymph Modulates Local Tissue Inflammation.
    Authors: Gomez D, Diehl M, Crosby E, Weinkopff T, Debes G
    J Immunol, 2015-09-09;195(8):3531-6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  312. Activated Brain Endothelial Cells Cross-Present Malaria Antigen.
    Authors: Howland S, Poh C, Renia L
    PLoS Pathog, 2015-06-05;11(6):e1004963.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  313. Mouse pancreatic beta cells express MHC class II and stimulate CD4(+) T cells to proliferate.
    Authors: Zhao Y, Scott N, Quah H, Krishnamurthy B, Bond F, Loudovaris T, Mannering S, Kay T, Thomas H
    Eur J Immunol, 2015-05-28;45(9):2494-503.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  314. Interferon Gamma, but not Calcitriol Improves the Osteopetrotic Phenotypes in ADO2 Mice.
    Authors: Alam I, Gray A, Acton D, Gerard-O'Riley R, Reilly A, Econs M
    J Bone Miner Res, 2015-05-14;30(11):2005-13.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  315. Dynamics of Circulating gammadelta T Cell Activity in an Immunocompetent Mouse Model of High-Grade Glioma.
    Authors: Beck B, Kim H, O'Brien R, Jadus M, Gillespie G, Cloud G, Hoa N, Langford C, Lopez R, Harkins L, Lamb L
    PLoS ONE, 2015-05-08;10(5):e0122387.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  316. Glycogen Synthase Kinase-3beta (GSK-3beta) Inhibition Enhances Dendritic Cell-based Cancer Vaccine Potency via Suppression of Interferon-gamma-induced Indoleamine 2,3-Dioxygenase Expression.
    Authors: Noh K, Son K, Jung I, Kang T, Choi C, Park Y
    J Biol Chem, 2015-03-26;290(19):12394-402.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  317. Defining immunological impact and therapeutic benefit of mild heating in a murine model of arthritis.
    Authors: Lee C, Kokolus K, Leigh N, Capitano M, Hylander B, Repasky E
    PLoS ONE, 2015-03-20;10(3):e0120327.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  318. Horizontal transfer of exosomal microRNAs transduce apoptotic signals between pancreatic beta-cells.
    Authors: Guay C, Menoud V, Rome S, Regazzi R
    Cell Commun Signal, 2015-03-19;13(0):17.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  319. Network integration of parallel metabolic and transcriptional data reveals metabolic modules that regulate macrophage polarization.
    Authors: Jha A, Huang S, Sergushichev A, Lampropoulou V, Ivanova Y, Loginicheva E, Chmielewski K, Stewart K, Ashall J, Everts B, Pearce E, Driggers E, Artyomov M
    Immunity, 2015-03-17;42(3):419-30.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  320. Epidermal Expression and Regulation of Interleukin-33 during Homeostasis and Inflammation: Strong Species Differences.
    Authors: Sundnes O, Pietka W, Loos T, Sponheim J, Rankin A, Pflanz S, Bertelsen V, Sitek J, Hol J, Haraldsen G, Khnykin D
    J Invest Dermatol, 2015-03-04;135(7):1771-80.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  321. Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus.
    Authors: Herbst S, Shah A, Mazon Moya M, Marzola V, Jensen B, Reed A, Birrell M, Saijo S, Mostowy S, Shaunak S, Armstrong-James D
    EMBO Mol Med, 2015-03-01;7(3):240-58.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  322. The cholesterol transporter ABCG1 links cholesterol homeostasis and tumour immunity.
    Authors: Sag D, Cekic C, Wu R, Linden J, Hedrick C
    Nat Commun, 2015-02-27;6(0):6354.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  323. Nuclear export inhibitors avert progression in preclinical models of inflammatory demyelination.
    Authors: Haines J, Herbin O, de la Hera B, Vidaurre O, Moy G, Sun Q, Fung H, Albrecht S, Alexandropoulos K, McCauley D, Chook Y, Kuhlmann T, Kidd G, Shacham S, Casaccia P
    Nat Neurosci, 2015-02-23;18(4):511-20.
    Species: Mouse
    Sample Types: In Vivo
  324. Disruption of an M. tuberculosis membrane protein causes a magnesium-dependent cell division defect and failure to persist in mice.
    Authors: Goodsmith N, Guo X, Vandal O, Vaubourgeix J, Wang R, Botella H, Song S, Bhatt K, Liba A, Salgame P, Schnappinger D, Ehrt S
    PLoS Pathog, 2015-02-06;11(2):e1004645.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  325. A dual cis-regulatory code links IRF8 to constitutive and inducible gene expression in macrophages.
    Authors: Mancino A, Termanini A, Barozzi I, Ghisletti S, Ostuni R, Prosperini E, Ozato K, Natoli G
    Genes Dev, 2015-01-30;29(4):394-408.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  326. Positive feedback regulation of type I IFN production by the IFN-inducible DNA sensor cGAS.
    Authors: Ma F, Li B, Liu S, Iyer S, Yu Y, Wu A, Cheng G
    J Immunol, 2015-01-21;194(4):1545-54.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  327. Impaired macrophage autophagy increases the immune response in obese mice by promoting proinflammatory macrophage polarization.
    Authors: Liu K, Zhao E, Ilyas G, Lalazar G, Lin Y, Haseeb M, Tanaka K, Czaja M
    Autophagy, 2015-01-01;11(2):271-84.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  328. Protective role for caspase-11 during acute experimental murine colitis.
    Authors: Oficjalska K, Raverdeau M, Aviello G, Wade S, Hickey A, Sheehan K, Corr S, Kay E, O'Neill L, Mills K, Creagh E
    J Immunol, 2014-12-29;194(3):1252-60.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  329. Suppression of Th1-mediated autoimmunity by embryonic stem cell-derived dendritic cells.
    Authors: Ikeda T, Hirata S, Takamatsu K, Haruta M, Tsukamoto H, Ito T, Uchino M, Ando Y, Nagafuchi S, Nishimura Y, Senju S
    PLoS ONE, 2014-12-18;9(12):e115198.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  330. Distinct functions of epidermal and myeloid-derived VEGF-A in skin tumorigenesis mediated by HPV8.
    Authors: Ding X, Lucas T, Marcuzzi G, Pfister H, Eming S
    Cancer Res, 2014-11-20;75(2):330-43.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  331. Molecular hydrogen in drinking water protects against neurodegenerative changes induced by traumatic brain injury.
    Authors: Dohi, Kenji, Kraemer, Brian C, Erickson, Michelle, McMillan, Pamela J, Kovac, Andrej, Flachbartova, Zuzana, Hansen, Kim M, Shah, Gul N, Sheibani, Nader, Salameh, Therese, Banks, William
    PLoS ONE, 2014-09-24;9(9):e108034.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  332. Reversal of beta cell de-differentiation by a small molecule inhibitor of the TGFbeta pathway.
    Authors: Blum B, Roose A, Barrandon O, Maehr R, Arvanites A, Davidow L, Davis J, Peterson Q, Rubin L, Melton D
    Elife, 2014-09-16;3(0):e02809.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  333. Delineating the importance of serum opsonins and the bacterial capsule in affecting the uptake and killing of Burkholderia pseudomallei by murine neutrophils and macrophages.
    Authors: Mulye M, Bechill M, Grose W, Ferreira V, Lafontaine E, Wooten R
    PLoS Negl Trop Dis, 2014-08-21;8(8):e2988.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  334. Peroxisome proliferator-activated receptor alpha protects capillary pericytes in the retina.
    Authors: Ding L, Cheng R, Hu Y, Takahashi Y, Jenkins A, Keech A, Humphries K, Gu X, Elliott M, Xia X, Ma J
    Am J Pathol, 2014-08-07;184(10):2709-20.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  335. IFN-gamma primes macrophage activation by increasing phosphatase and tensin homolog via downregulation of miR-3473b.
    Authors: Wu C, Xue Y, Wang P, Lin L, Liu Q, Li N, Xu J, Cao X
    J Immunol, 2014-08-04;193(6):3036-44.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  336. Control of intracellular Francisella tularensis by different cell types and the role of nitric oxide.
    Authors: Newstead S, Gates A, Hartley M, Rowland C, Williamson E, Lukaszewski R
    J Immunol Res, 2014-07-21;2014(0):694717.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  337. Synergistic up-regulation of CXCL10 by virus and IFN gamma in human airway epithelial cells.
    Authors: Oslund K, Zhou X, Lee B, Zhu L, Duong T, Shih R, Baumgarth N, Hung L, Wu R, Chen Y
    PLoS ONE, 2014-07-17;9(7):e100978.
    Species: Mouse
    Sample Types: In Vivo, Whole Cells
    Applications: Bioassay, In Vivo
  338. PKM2 regulates the Warburg effect and promotes HMGB1 release in sepsis.
    Authors: Yang L, Xie M, Yang M, Yu Y, Zhu S, Hou W, Kang R, Lotze M, Billiar T, Wang H, Cao L, Tang D
    Nat Commun, 2014-07-14;5(0):4436.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  339. Curcumin ameliorates autoimmune diabetes. Evidence in accelerated murine models of type 1 diabetes.
    Authors: Castro C, Barcala Tabarrozzi A, Winnewisser J, Gimeno M, Antunica Noguerol M, Liberman A, Paz D, Dewey R, Perone M
    Clin Exp Immunol, 2014-07-01;177(1):149-60.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  340. Cancer affects microRNA expression, release, and function in cardiac and skeletal muscle.
    Authors: Chen D, Goswami C, Burnett R, Anjanappa M, Bhat-Nakshatri P, Muller W, Nakshatri H
    Cancer Res, 2014-06-30;74(16):4270-81.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  341. Paneth cell extrusion and release of antimicrobial products is directly controlled by immune cell-derived IFN-gamma.
    Authors: Farin H, Karthaus W, Kujala P, Rakhshandehroo M, Schwank G, Vries R, Kalkhoven E, Nieuwenhuis E, Clevers H
    J Exp Med, 2014-06-30;211(7):1393-405.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  342. Site-specific chemokine expression regulates central nervous system inflammation and determines clinical phenotype in autoimmune encephalomyelitis.
    Authors: Stoolman J, Duncker P, Huber A, Segal B
    J Immunol, 2014-06-13;193(2):564-70.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  343. USP18 is crucial for IFN-gamma-mediated inhibition of B16 melanoma tumorigenesis and antitumor immunity.
    Authors: Hong B, Li H, Lu Y, Zhang M, Zheng Y, Qian J, Yi Q
    Mol Cancer, 2014-05-31;13(0):132.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  344. Autophagy regulates the therapeutic potential of mesenchymal stem cells in experimental autoimmune encephalomyelitis.
    Authors: Dang, Shipeng, Xu, Huanbai, Xu, Congfeng, Cai, Wei, Li, Qian, Cheng, Yiji, Jin, Min, Wang, Ru-Xing, Peng, Yongde, Zhang, Yi, Wu, Changpin, He, Xiaozhou, Wan, Bing, Zhang, Yanyun
    Autophagy, 2014-05-14;10(7):1301-15.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  345. Steady-state antigen scavenging, cross-presentation, and CD8+ T cell priming: a new role for lymphatic endothelial cells.
    Authors: Hirosue S, Vokali E, Raghavan V, Rincon-Restrepo M, Lund A, Corthesy-Henrioud P, Capotosti F, Halin Winter C, Hugues S, Swartz M
    J Immunol, 2014-05-02;192(11):5002-11.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  346. Intramolecular polyspecificity in CD4 T-cell recognition of Ad-restricted epitopes of proteoglycan aggrecan.
    Authors: Falconer J, Lowes K, Furmanski A, Dyson J, Ng W, Robinson J
    Immunology, 2014-05-01;142(1):101-110.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  347. All-trans retinoic acid induces arginase-1 and inducible nitric oxide synthase-producing dendritic cells with T cell inhibitory function.
    Authors: Bhatt S, Qin J, Bennett C, Qian S, Fung J, Hamilton T, Lu L
    J Immunol, 2014-04-30;192(11):5098-108.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  348. MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration.
    Authors: Cebrian C, Zucca F, Mauri P, Steinbeck J, Studer L, Scherzer C, Kanter E, Budhu S, Mandelbaum J, Vonsattel J, Zecca L, Loike J, Sulzer D
    Nat Commun, 2014-04-16;5(0):3633.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  349. NRROS negatively regulates reactive oxygen species during host defence and autoimmunity.
    Authors: Noubade, Rajkumar, Wong, Kit, Ota, Naruhisa, Rutz, Sascha, Eidenschenk, Celine, Valdez, Patricia, Ding, Jiabing, Peng, Ivan, Sebrell, Andrew, Caplazi, Patrick, DeVoss, Jason, Soriano, Robert H, Sai, Tao, Lu, Rongze, Modrusan, Zora, Hackney, Jason, Ouyang, Wenjun
    Nature, 2014-04-13;509(7499):235-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  350. The primary cilium influences interleukin-1beta-induced NFkappaB signalling by regulating IKK activity.
    Authors: Wann A, Chapple J, Knight M
    Cell Signal, 2014-04-12;26(8):1735-42.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  351. Interferon regulatory factor 1 restricts gammaherpesvirus replication in primary immune cells.
    Authors: Mboko W, Mounce B, Emmer J, Darrah E, Patel S, Tarakanova V
    J Virol, 2014-04-09;88(12):6993-7004.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  352. Axl receptor blockade ameliorates pulmonary pathology resulting from primary viral infection and viral exacerbation of asthma.
    Authors: Shibata T, Habiel D, Coelho A, Kunkel S, Lukacs N, Hogaboam C
    J Immunol, 2014-03-21;192(8):3569-81.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: ELISA (Standard)
  353. Regulation of experimental autoimmune encephalomyelitis by TPL-2 kinase.
    Authors: Sriskantharajah S, Guckel E, Tsakiri N, Kierdorf K, Brender C, Ben-Addi A, Veldhoen M, Tsichlis P, Stockinger B, O'Garra A, Prinz M, Kollias G, Ley S
    J Immunol, 2014-03-17;192(8):3518-29.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  354. Improved repair of dermal wounds in mice lacking microRNA-155.
    Authors: van Solingen C, Araldi E, Chamorro-Jorganes A, Fernandez-Hernando C, Suarez Y
    J Cell Mol Med, 2014-03-17;18(6):1104-12.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  355. IL-13 orchestrates resolution of chronic intestinal inflammation via phosphorylation of glycogen synthase kinase-3beta.
    Authors: Fichtner-Feigl S, Kesselring R, Martin M, Obermeier F, Ruemmele P, Kitani A, Brunner S, Haimerl M, Geissler E, Strober W, Schlitt H
    J Immunol, 2014-03-14;192(8):3969-80.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  356. Collective nitric oxide production provides tissue-wide immunity during Leishmania infection.
    Authors: Olekhnovitch R, Ryffel B, Muller A, Bousso P
    J Clin Invest, 2014-03-10;124(4):1711-22.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  357. Recombinant Wnt3a and Wnt5a elicit macrophage cytokine production and tolerization to microbial stimulation via Toll-like receptor 4.
    Authors: Yu C, Nguyen T, Irvine K, Sweet M, Frazer I, Blumenthal A
    Eur J Immunol, 2014-03-07;44(5):1480-90.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  358. Preferential macrophage recruitment and polarization in LPS-induced animal model for COPD: noninvasive tracking using MRI.
    Authors: Al Faraj, Achraf, Sultana Shaik, Asma, Pureza, Mary Ang, Alnafea, Mohammad, Halwani, Rabih
    PLoS ONE, 2014-03-05;9(3):e90829.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  359. TGFbeta-mediated suppression of CD248 in non-cancer cells via canonical Smad-dependent signaling pathways is uncoupled in cancer cells.
    Authors: Suresh Babu S, Valdez Y, Xu A, O'Byrne A, Calvo F, Lei V, Conway E
    BMC Cancer, 2014-02-20;14(0):113.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  360. Unique macrophages different from M1/M2 macrophages inhibit T cell mitogenesis while upregulating Th17 polarization.
    Authors: Tatano Y, Shimizu T, Tomioka H
    Sci Rep, 2014-02-20;4(0):4146.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  361. NK cells are required for dendritic cell-based immunotherapy at the time of tumor challenge.
    Authors: Bouwer A, Saunderson S, Caldwell F, Damani T, Pelham S, Dunn A, Jack R, Stoitzner P, McLellan A
    J Immunol, 2014-01-29;192(5):2514-21.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  362. Endothelial cell-derived chemerin promotes dendritic cell transmigration.
    Authors: Gonzalvo-Feo S, Del Prete A, Pruenster M, Salvi V, Wang L, Sironi M, Bierschenk S, Sperandio M, Vecchi A, Sozzani S
    J Immunol, 2014-01-27;192(5):2366-73.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  363. Comparison of osteogenic differentiation of embryonic stem cells and primary osteoblasts revealed by responses to IL-1beta, TNF-alpha, and IFN-gamma.
    Authors: Sidney L, Kirkham G, Buttery L
    Stem Cells Dev, 2014-01-23;23(6):605-17.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  364. Mesenchymal stem cells use IDO to regulate immunity in tumor microenvironment.
    Authors: Ling W, Zhang J, Yuan Z, Ren G, Zhang L, Chen X, Rabson A, Roberts A, Wang Y, Shi Y
    Cancer Res, 2014-01-22;74(5):1576-87.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  365. A novel immunomodulatory function of PHLPP1: inhibition of iNOS via attenuation of STAT1 ser727 phosphorylation in mouse macrophages.
    Authors: Alamuru N, Behera S, Butchar J, Tridandapani S, Kaimal Suraj S, Babu P, Hasnain S, Ehtesham N, Parsa K
    J Leukoc Biol, 2014-01-17;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  366. IL-4/IL-13-dependent and independent expression of miR-124 and its contribution to M2 phenotype of monocytic cells in normal conditions and during allergic inflammation.
    Authors: Veremeyko, Tatyana, Siddiqui, Shafiudd, Sotnikov, Ilya, Yung, Amanda, Ponomarev, Eugene D
    PLoS ONE, 2013-12-16;8(12):e81774.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  367. Therapeutic efficacy of suppressing the Jak/STAT pathway in multiple models of experimental autoimmune encephalomyelitis.
    Authors: Liu Y, Holdbrooks A, De Sarno P, Rowse A, Yanagisawa L, McFarland B, Harrington L, Raman C, Sabbaj S, Benveniste E, Qin H
    J Immunol, 2013-12-09;192(1):59-72.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  368. TGF-beta promotes immune responses in the presence of mesenchymal stem cells.
    Authors: Xu C, Yu P, Han X, DU L, Gan J, Wang Y, Shi Y
    J Immunol, 2013-11-29;192(1):103-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  369. TLR1/2 ligand-stimulated mouse liver endothelial cells secrete IL-12 and trigger CD8+ T cell immunity in vitro.
    Authors: Liu, Jia, Jiang, Min, Ma, Zhiyong, Dietze, Kirsten, Zelinskyy, Gennadiy, Yang, Donglian, Dittmer, Ulf, Schlaak, Joerg F, Roggendorf, Michael, Lu, Mengji
    J Immunol, 2013-11-13;191(12):6178-90.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  370. Development of a primary mouse intestinal epithelial cell monolayer culture system to evaluate factors that modulate IgA transcytosis.
    Authors: Moon C, VanDussen K, Miyoshi H, Stappenbeck T
    Mucosal Immunol, 2013-11-13;7(4):818-28.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  371. The exonuclease Trex1 restrains macrophage proinflammatory activation.
    Authors: Pereira-Lopes S, Celhar T, Sans-Fons G, Serra M, Fairhurst A, Lloberas J, Celada A
    J Immunol, 2013-11-11;191(12):6128-35.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  372. Important scaffold function of the Janus kinase 2 uncovered by a novel mouse model harboring a Jak2 activation-loop mutation.
    Authors: Keil E, Finkenstadt D, Wufka C, Trilling M, Liebfried P, Strobl B, Muller M, Pfeffer K
    Blood, 2013-10-29;123(4):520-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  373. Essential role of CD11a in CD8+ T-cell accumulation and activation in adipose tissue.
    Authors: Jiang E, Perrard X, Yang D, Khan I, Perrard J, Smith C, Ballantyne C, Wu H
    Arterioscler Thromb Vasc Biol, 2013-10-24;34(1):34-43.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  374. An antioxidant role for catecholate siderophores in Salmonella.
    Authors: Achard, Maud E S, Chen, Kaiwen W, Sweet, Matthew, Watts, Rebecca, Schroder, Kate, Schembri, Mark A, McEwan, Alastair
    Biochem J, 2013-09-15;454(3):543-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  375. Galectin-9 protein is up-regulated in astrocytes by tumor necrosis factor and promotes encephalitogenic T-cell apoptosis.
    Authors: Steelman A, Smith R, Welsh C, Li J
    J Biol Chem, 2013-07-08;288(33):23776-87.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  376. Calmodulin-dependent protein kinase II/cAMP response element-binding protein/Wnt/beta-catenin signaling cascade regulates angiotensin II-induced podocyte injury and albuminuria.
    Authors: Jiang L, Xu L, Song Y, Li J, Mao J, Zhao A, He W, Yang J, Dai C
    J Biol Chem, 2013-06-26;288(32):23368-79.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  377. Guanylate-binding protein 1 (Gbp1) contributes to cell-autonomous immunity against Toxoplasma gondii.
    Authors: Selleck E, Fentress S, Beatty W, Degrandi D, Pfeffer K, Virgin H, Macmicking J, Sibley L
    PLoS Pathog, 2013-04-25;9(4):e1003320.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  378. Regulation and migratory role of P-selectin ligands during intestinal inflammation.
    Authors: Hoffmann U, Pink M, Lauer U, Heimesaat M, Winsauer C, Kruglov A, Schlawe K, Leichsenring C, Liesenfeld O, Hamann A, Syrbe U
    PLoS ONE, 2013-04-22;8(4):e62055.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  379. Anti-CD70 immunocytokines for exploitation of interferon-gamma-induced RIP1-dependent necrosis in renal cell carcinoma.
    Authors: Chen P, Nogusa S, Thapa R, Shaller C, Simmons H, Peri S, Adams G, Balachandran S
    PLoS ONE, 2013-04-17;8(4):e61446.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  380. Cannabinoid 1 receptors in keratinocytes modulate proinflammatory chemokine secretion and attenuate contact allergic inflammation.
    Authors: Gaffal E, Cron M, Glodde N, Bald T, Kuner R, Zimmer A, Lutz B, Tuting T
    J Immunol, 2013-04-12;190(10):4929-36.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  381. CD43-mediated IFN-gamma production by CD8+ T cells promotes abdominal aortic aneurysm in mice.
    Authors: Zhou H, Yan H, Cannon J, Springer L, Green J, Pham C
    J Immunol, 2013-04-12;190(10):5078-85.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  382. Decorin potentiates interferon-gamma activity in a model of allergic inflammation.
    Authors: Bocian C, Urbanowitz A, Owens R, Iozzo R, Gotte M, Seidler D
    J Biol Chem, 2013-03-04;288(18):12699-711.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  383. Endoglin regulates the activation and quiescence of endothelium by participating in canonical and non-canonical TGF-beta signaling pathways.
    Authors: Park S, Dimaio T, Liu W, Wang S, Sorenson C, Sheibani N
    J Cell Sci, 2013-02-15;126(0):1392-405.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  384. Everolimus limits aortic aneurysm in the apolipoprotein E-deficient mouse by downregulating C-C chemokine receptor 2 positive monocytes.
    Authors: Moran C, Jose R, Moxon J, Roomberg A, Norman P, Rush C, Korner H, Golledge J
    Arterioscler Thromb Vasc Biol, 2013-02-07;33(4):814-21.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  385. Association of beta-catenin with P-Smad3 but not LEF-1 dissociates in vitro profibrotic from anti-inflammatory effects of TGF-beta1.
    Authors: Tian X, Zhang J, Tan T, Lyons J, Zhao H, Niu B, Lee S, Tsatralis T, Zhao Y, Wang Y, Cao Q, Wang C, Wang Y, Lee V, Kahn M, Zheng G, Harris D
    J Cell Sci, 2012-11-30;126(0):67-76.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  386. Differentially imprinted innate immunity by mucosal boost vaccination determines antituberculosis immune protective outcomes, independent of T-cell immunity.
    Authors: Jeyanathan M, Damjanovic D, Shaler C, Lai R, Wortzman M, Yin C, Zganiacz A, Lichty B, Xing Z
    Mucosal Immunol, 2012-11-07;6(3):612-25.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  387. IL-9-producing invariant NKT cells protect against DSS-induced colitis in an IL-4-dependent manner.
    Authors: Kim H, Chung D
    Mucosal Immunol, 2012-08-15;6(2):347-57.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  388. ATP release and autocrine signaling through P2X4 receptors regulate gammadelta T cell activation.
    Authors: Manohar M, Hirsh M, Chen Y, Woehrle T, Karande A, Junger W
    J Leukoc Biol, 2012-06-29;92(4):787-94.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  389. Regulation of innate CD8+ T-cell activation mediated by cytokines.
    Proc Natl Acad Sci U S A, 2012-06-04;109(25):9971-6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  390. Interferon gamma inhibits adipogenesis in vitro and prevents marrow fat infiltration in oophorectomized mice.
    Authors: Vidal C, Bermeo S, Li W, Huang D, Kremer R, Duque G
    Stem Cells, 2012-05-01;30(5):1042-8.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  391. Host-derived MCP-1 and MIP-1alpha regulate protective anti-tumor immunity to localized and metastatic B16 melanoma.
    Authors: Nakasone Y, Fujimoto M, Matsushita T, Hamaguchi Y, Huu DL, Yanaba M, Sato S, Takehara K, Hasegawa M
    Am. J. Pathol., 2011-10-26;180(1):365-74.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  392. IL-6 mediates the susceptibility of glycoprotein 130 hypermorphs to Toxoplasma gondii.
    J. Immunol., 2011-05-23;187(1):350-60.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  393. Hematopoietic cell-restricted deletion of CD36 reduces high-fat diet-induced macrophage infiltration and improves insulin signaling in adipose tissue.
    Authors: Nicholls HT, Kowalski G, Kennedy DJ
    Diabetes, 2011-03-04;60(4):1100-10.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  394. Development of an IL-15-autocrine CD8 T-cell leukemia in IL-15-transgenic mice requires the cis expression of IL-15R alpha.
    Authors: Sato N, Sabzevari H, Fu S, Ju W, Petrus MN, Bamford RN, Waldmann TA, Tagaya Y
    Blood, 2011-02-08;117(15):4032-40.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  395. The C5a receptor impairs IL-12-dependent clearance of Porphyromonas gingivalis and is required for induction of periodontal bone loss.
    Authors: Liang S, Krauss JL, Domon H, McIntosh ML, Hosur KB, Qu H, Li F, Tzekou A, Lambris JD, Hajishengallis G
    J. Immunol., 2010-12-13;186(2):869-77.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  396. IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation.
    Authors: Zaki MH, Vogel P, Body-Malapel M, Lamkanfi M, Kanneganti TD
    J. Immunol., 2010-09-20;185(8):4912-20.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  397. IL-1RL2 and its ligands contribute to the cytokine network in psoriasis.
    Authors: Blumberg H, Dinh H, Dean C, Trueblood ES, Bailey K, Shows D, Bhagavathula N, Aslam MN, Varani J, Towne JE, Sims JE
    J. Immunol., 2010-09-10;185(7):4354-62.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  398. Commensal microflora and interferon-gamma promote steady-state interleukin-7 production in vivo.
    Authors: Shalapour S, Deiser K, Sercan O, Tuckermann J, Minnich K, Willimsky G, Blankenstein T, Hammerling GJ, Arnold B, Schuler T
    Eur. J. Immunol., 2010-09-01;40(9):2391-400.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  399. Proinflammatory clearance of apoptotic neutrophils induces an IL-12(low)IL-10(high) regulatory phenotype in macrophages.
    Authors: Filardy AA, Pires DR, Nunes MP, Takiya CM, Freire-de-Lima CG, Ribeiro-Gomes FL, DosReis GA
    J. Immunol., 2010-07-21;185(4):2044-50.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  400. TGFbeta2-mediated production of hyaluronan is important for the induction of epicardial cell differentiation and invasion.
    Authors: Craig EA, Craig E, Austin AF, Austin A, Vaillancourt RR, Vaillancourt R, Barnett JV, Camenisch TD, Camenisch T
    Exp Cell Res, 2010-07-13;316(20):3397-405.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  401. Phosphatidylinositol 3-kinase/protein kinase Cdelta activation induces close homolog of adhesion molecule L1 (CHL1) expression in cultured astrocytes.
    Authors: Wu J, Wrathall JR, Schachner M
    Glia, 2010-02-01;58(3):315-28.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  402. T-cell recruitment and Th1 polarization in adipose tissue during diet-induced obesity in C57BL/6 mice.
    Authors: Strissel KJ, DeFuria J, Shaul ME, Bennett G, Greenberg AS, Obin MS
    Obesity (Silver Spring), 2010-01-28;18(10):1918-25.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  403. Thymic regulation of autoimmune disease by accelerated differentiation of Foxp3+ regulatory T cells through IL-7 signaling pathway.
    Authors: Chen X, Fang L, Song S, Guo TB, Liu A, Zhang JZ
    J. Immunol., 2009-10-19;183(10):6135-44.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  404. A novel role for constitutively expressed epithelial-derived chemokines as antibacterial peptides in the intestinal mucosa.
    Authors: Kotarsky K, Sitnik KM, Stenstad H, Kotarsky H, Schmidtchen A, Koslowski M, Wehkamp J, Agace WW
    Mucosal Immunol, 2009-10-07;3(1):40-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  405. Tolerogenic signals delivered by dendritic cells to T cells through a galectin-1-driven immunoregulatory circuit involving interleukin 27 and interleukin 10.
    Authors: Ilarregui JM, Croci DO, Bianco GA, Toscano MA, Salatino M, Vermeulen ME, Geffner JR, Rabinovich GA
    Nat. Immunol., 2009-08-09;10(9):981-91.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  406. E-prostanoid 3 receptor deletion improves pulmonary host defense and protects mice from death in severe Streptococcus pneumoniae infection.
    Authors: Aronoff DM, Lewis C, Serezani CH, Eaton KA, Goel D, Phipps JC, Peters-Golden M, Mancuso P
    J. Immunol., 2009-07-27;183(4):2642-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  407. T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes.
    Authors: Guarda G, Dostert C, Staehli F, Cabalzar K, Castillo R, Tardivel A, Schneider P, Tschopp J
    Nature, 2009-06-03;460(7252):269-73.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  408. Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNgamma production.
    Authors: Lemos HP, Grespan R, Vieira SM, Cunha TM, Verri WA, Fernandes KS, Souto FO, McInnes IB, Ferreira SH, Liew FY, Cunha FQ
    Proc. Natl. Acad. Sci. U.S.A., 2009-03-16;106(14):5954-9.
    Species: Mouse
    Sample Types: In Vivo, N/A
    Applications: ELISA (Standard), In Vivo
  409. ST2 deficient mice display a normal host defense against pulmonary infection with Mycobacterium tuberculosis.
    Authors: Wieland CW, van der Windt GJ, Florquin S, McKenzie AN, van der Poll T
    Microbes Infect., 2009-03-13;11(4):524-30.
    Applications: ELISA (Standard)
  410. Effects of Signal 3 during CD8 T cell priming: Bystander production of IL-12 enhances effector T cell expansion but promotes terminal differentiation.
    Authors: Cui W, Joshi NS, Jiang A, Kaech SM
    Vaccine, 2009-02-06;27(15):2177-87.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  411. Cure of established GL261 mouse gliomas after combined immunotherapy with GM-CSF and IFNgamma is mediated by both CD8+ and CD4+ T-cells.
    Authors: Smith KE, Fritzell S, Badn W, Eberstal S, Janelidze S, Visse E, Darabi A, Siesjo P
    Int. J. Cancer, 2009-02-01;124(3):630-7.
    Species: Mouse
    Sample Types: In Vivo, Whole Cells
    Applications: Bioassay, In Vivo
  412. Vaccination route that induces transforming growth factor beta production fails to elicit protective immunity against Leishmania donovani infection.
    Authors: Bhowmick S, Mazumdar T, Ali N
    Infect. Immun., 2009-01-21;77(4):1514-23.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  413. The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+ T cells.
    Authors: Dienz O, Eaton SM, Bond JP, Neveu W, Moquin D, Noubade R, Briso EM, Charland C, Leonard WJ, Ciliberto G, Teuscher C, Haynes L, Rincon M
    J. Exp. Med., 2009-01-12;206(1):69-78.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  414. IFN-gamma down-regulates Secretoglobin 3A1 gene expression.
    Authors: Yamada A, Suzuki D, Miyazono A, Oshima K, Kamiya A, Zhao B, Takami M, Donnelly RP, Itabe H, Yamamoto M, Kimura S, Kamijo R
    Biochem. Biophys. Res. Commun., 2009-01-09;379(4):964-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  415. Protein Never in Mitosis Gene A Interacting-1 (PIN1) regulates degradation of inducible nitric oxide synthase in endothelial cells.
    Authors: Liu T, Huang Y, Likhotvorik RI, Keshvara L, Hoyt DG
    Am. J. Physiol., Cell Physiol., 2008-07-23;295(3):C819-27.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  416. Interferon-gamma limits the availability of iron for intramacrophage Salmonella typhimurium.
    Authors: Nairz M, Fritsche G, Brunner P, Talasz H, Hantke K, Weiss G
    Eur. J. Immunol., 2008-07-01;38(7):1923-36.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  417. CD14 contributes to pulmonary inflammation and mortality during murine tuberculosis.
    Authors: Wieland CW, van der Windt GJ, Wiersinga WJ, Florquin S, van der Poll T
    Immunology, 2008-04-03;125(2):272-9.
    Applications: ELISA (Standard)
  418. IFN-gamma production during initial infection determines the outcome of reinfection with respiratory syncytial virus.
    Authors: Lee YM, Miyahara N, Takeda K, Prpich J, Oh A, Balhorn A, Joetham A, Gelfand EW, Dakhama A
    Am. J. Respir. Crit. Care Med., 2007-10-25;177(2):208-18.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  419. Maternal immune activation alters fetal brain development through interleukin-6.
    Authors: Smith SE, Li J, Garbett K, Mirnics K, Patterson PH
    J. Neurosci., 2007-10-03;27(40):10695-702.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  420. Differential ex vivo nitric oxide production by acutely isolated neonatal and adult microglia.
    Authors: Schell JB, Crane CA, Smith MF, Roberts MR
    J. Neuroimmunol., 2007-08-15;189(1):75-87.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  421. The direct action of 1alpha,25(OH)2-vitamin D3 on purified mouse Langerhans cells.
    Authors: Fujita H, Asahina A, Komine M, Tamaki K
    Cell. Immunol., 2007-05-15;245(2):70-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  422. Elevated neuronal expression of CD200 protects Wlds mice from inflammation-mediated neurodegeneration.
    Authors: Chitnis T, Imitola J, Wang Y, Elyaman W, Chawla P, Sharuk M, Raddassi K, Bronson RT, Khoury SJ
    Am. J. Pathol., 2007-05-01;170(5):1695-712.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  423. Overexpression of suppressor of cytokine signaling-5 in T cells augments innate immunity during septic peritonitis.
    Authors: Watanabe H, Kubo M, Numata K, Takagi K, Mizuta H, Okada S, Ito T, Matsukawa A
    J. Immunol., 2006-12-15;177(12):8650-7.
    Applications: ELISA (Standard)
  424. Targeted deletion of CCR2 impairs deep vein thombosis resolution in a mouse model.
    Authors: Henke PK, Pearce CG, Moaveni DM, Moore AJ, Lynch EM, Longo C, Varma M, Dewyer NA, Deatrick KB, Upchurch GR, Wakefield TW, Hogaboam C, Kunkel SL
    J. Immunol., 2006-09-01;177(5):3388-97.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  425. Glatiramer acetate fights against Alzheimer's disease by inducing dendritic-like microglia expressing insulin-like growth factor 1.
    Authors: Butovsky O, Koronyo-Hamaoui M, Kunis G, Ophir E, Landa G, Cohen H, Schwartz M
    Proc. Natl. Acad. Sci. U.S.A., 2006-07-24;103(31):11784-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  426. Induction and blockage of oligodendrogenesis by differently activated microglia in an animal model of multiple sclerosis.
    Authors: Butovsky O, Landa G, Kunis G, Ziv Y, Avidan H, Greenberg N, Schwartz A, Smirnov I, Pollack A, Jung S, Schwartz M
    J. Clin. Invest., 2006-03-23;116(4):905-15.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  427. Glechoma hederacea inhibits inflammatory mediator release in IFN-gamma and LPS-stimulated mouse peritoneal macrophages.
    Authors: An HJ, Jeong HJ, Um JY, Kim HM, Hong SH
    J Ethnopharmacol, 2006-03-10;106(3):418-24.
    Species: Mouse
    Sample Types: In Vivo, Whole Cells
    Applications: Bioassay, In Vivo
  428. Differential Growth of IFN-beta-Engineered Tumor Cells in Nude and IFN Receptor-Null Mice.
    Authors: Zhang F, Lee J, Wang D, Dong Z
    J. Interferon Cytokine Res., 2006-02-01;26(2):108-18.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  429. Microglia activated by IL-4 or IFN-gamma differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells.
    Authors: Butovsky O, Ziv Y, Schwartz A, Landa G, Talpalar AE, Pluchino S, Martino G, Schwartz M
    Mol. Cell. Neurosci., 2005-11-16;31(1):149-60.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  430. Inhibition of interferon-stimulated JAK-STAT signaling by a tick-borne flavivirus and identification of NS5 as an interferon antagonist.
    Authors: Best SM, Morris KL, Shannon JG, Robertson SJ, Mitzel DN, Park GS, Boer E, Wolfinbarger JB, Bloom ME
    J. Virol., 2005-10-01;79(20):12828-39.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  431. Sequential ELISA to profile multiple cytokines from small volumes.
    Authors: Osuchowski MF, Siddiqui J, Copeland S, Remick DG
    J. Immunol. Methods, 2005-07-01;302(1):172-81.
    Applications: ELISA (Standard)
  432. Dendritic cells and NK cells stimulate bystander T cell activation in response to TLR agonists through secretion of IFN-alpha beta and IFN-gamma.
    Authors: Kamath AT, Sheasby CE, Tough DF
    J. Immunol., 2005-01-15;174(2):767-76.
    Species: Mouse
    Sample Types: Cell Culture Supernates
    Applications: Bioassay
  433. Gamma interferon does not enhance clearance of Pseudomonas aeruginosa but does amplify a proinflammatory response in a murine model of postseptic immunosuppression.
    Authors: Murphey ED, Herndon DN, Sherwood ER
    Infect. Immun., 2004-12-01;72(12):6892-901.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  434. Stimulation of toll-like receptor 2 by Coxiella burnetii is required for macrophage production of pro-inflammatory cytokines and resistance to infection.
    Authors: Zamboni DS, Campos MA, Torrecilhas AC, Kiss K, Samuel JE, Golenbock DT, Lauw FN, Roy CR, Almeida IC, Gazzinelli RT
    J. Biol. Chem., 2004-10-13;279(52):54405-15.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  435. IL-22 increases the innate immunity of tissues.
    Authors: Wolk K, Kunz S, Witte E, Friedrich M, Asadullah K, Sabat R
    Immunity, 2004-08-01;21(2):241-54.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  436. Increased and long-term generation of dendritic cells with reduced function from IL-6-deficient bone marrow.
    Authors: Bleier JI, Pillarisetty VG, Shah AB, DeMatteo RP
    J. Immunol., 2004-06-15;172(12):7408-16.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  437. IFN-alpha priming results in a gain of proinflammatory function by IL-10: implications for systemic lupus erythematosus pathogenesis.
    Authors: Sharif MN, Tassiulas I, Hu Y, Mecklenbrauker I, Tarakhovsky A, Ivashkiv LB
    J. Immunol., 2004-05-15;172(10):6476-81.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  438. A disintegrin and metalloproteinase 10-mediated cleavage and shedding regulates the cell surface expression of CXC chemokine ligand 16.
    Authors: Gough PJ, Garton KJ, Wille PT, Rychlewski M, Dempsey PJ, Raines EW
    J. Immunol., 2004-03-15;172(6):3678-85.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  439. Mouse strain differences in plasmacytoid dendritic cell frequency and function revealed by a novel monoclonal antibody.
    Authors: Asselin-Paturel C, Brizard G, Pin JJ, Briere F, Trinchieri G
    J. Immunol., 2003-12-15;171(12):6466-77.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  440. Intracellular thiols contribute to Th2 function via a positive role in IL-4 production.
    Authors: Monick MM, Samavati L, Butler NS, Mohning M, Powers LS, Yarovinsky T, Spitz DR, Hunninghake GW
    J. Immunol., 2003-11-15;171(10):5107-15.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  441. Cooperative B7-1/2 (CD80/CD86) and B7-DC costimulation of CD4+ T cells independent of the PD-1 receptor.
    Authors: Shin T, Kennedy G, Gorski K, Tsuchiya H, Koseki H, Azuma M, Yagita H, Chen L, Powell J, Pardoll D, Housseau F
    J. Exp. Med., 2003-07-07;198(1):31-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  442. Impact of interleukin-13 responsiveness on the synthetic and proliferative properties of Th1- and Th2-type pulmonary granuloma fibroblasts.
    Authors: Jakubzick C, Choi ES, Kunkel SL, Joshi BH, Puri RK, Hogaboam CM
    Am. J. Pathol., 2003-05-01;162(5):1475-86.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  443. IFN-gamma, but not Fas, mediates reduction of allergen-induced mucous cell metaplasia by inducing apoptosis.
    Authors: Shi ZO, Fischer MJ, De Sanctis GT, Schuyler MR, Tesfaigzi Y
    J. Immunol., 2002-05-01;168(9):4764-71.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo

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Recombinant Mouse IFN-gamma Protein
By Anonymous on 10/20/2021
Application: In vitro bioactivity in cell culture
Recombinant Mouse IFN-gamma Protein
By Anonymous on 06/18/2021
Application: Immunoassay Standard
Immunoassay Standard Recombinant Mouse IFN-gamma Protein 485-MI
Recombinant Mouse IFN-gamma Protein
By Anonymous on 04/23/2021
Application: In vitro bioactivity in cell culture
Recombinant Mouse IFN-gamma Protein
By Anonymous on 01/27/2021
Application: In vivo study
Recombinant Mouse IFN-gamma Protein
By Tahmineh Safaie on 10/09/2020
Application: In vitro bioactivity in cell culture

Balb/c Mice solenocytes were treated with mrIFN-gamma and the intracellular IDO-1 expression was measured in CD45/CD11c+ population

In vitro bioactivity in cell culture Recombinant Mouse IFN-gamma Protein 485-MI
Recombinant Mouse IFN-gamma Protein
By Anonymous on 03/06/2020
Application: In vitro bioactivity in cell culture
Recombinant Mouse IFN-gamma Protein
By Anonymous on 08/07/2019
Application: Immunoassay Standard
Immunoassay Standard Recombinant Mouse IFN-gamma Protein 485-MI
Recombinant Mouse IFN-gamma Protein
By jayeeta giri on 01/28/2019
Application: In vitro bioactivity in cell culture
Recombinant Mouse IFN-gamma Protein
By Danlee Enzler on 04/02/2018
Application: In vitro bioactivity in cell culture
Recombinant Mouse IFN-gamma Protein
By Danlee Enzler on 04/02/2018
Application: In vitro bioactivity in cell culture
Recombinant Mouse IFN-gamma Protein
By Anonymous on 11/27/2017
Application: Immunoassay Standard
Immunoassay Standard Recombinant Mouse IFN-gamma Protein 485-MI
Recombinant Mouse IFN-gamma Protein
By Chandrasekaran Sambamurthy on 11/20/2017
Application: In vitro bioactivity in cell culture
Recombinant Mouse IFN-gamma Protein
By Tima Thomas on 01/21/2016
Application: In vitro bioactivity in cell culture