Retigabine
Chemical Name: Ethyl [2-amino-4-[[(4-fluorophenyl)methyl]amino]phenyl]carbamate
Purity: ≥98%
Biological Activity
Retigabine is a KV7 (KCNQ) channel activator (EC50 values are 0.6 - 100 μM for KV7.1 - KV7.5). Anticonvulsant. Orally bioavailable.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
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Background References
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Retigabine: chemical synthesis to clinical application.
Blackburn-Munro et al.
CNS Drug Rev., 2005;11:1
Product Datasheets
Citation for Retigabine
The citations listed below are publications that use Tocris products. Selected citations for Retigabine include:
1 Citation: Showing 1 - 1
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Molecular expression and pharmacological evidence for a functional role of kv7 channel subtypes in Guinea pig urinary bladder smooth muscle.
Authors: Afeli Et al.
PLoS One 2013;8:e75875
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