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RIPK2 inhibitor 1

Catalog #: 6603 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
6603/50
6603/10
RIPK2 inhibitor 1 | CAS No. 1290490-78-6 | RIP Kinase Inhibitors
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Description: Potent RIPK2 inhibitor

Chemical Name: 3-(Benzoylamino)-4-methyl-N-[3-(1-methyl-1H-imidazol-2-yl)phenyl]benzamide

Purity: ≥98%

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Biological Activity

RIPK2 inhibitor 1 is a potent receptor-interacting protein kinase 2 (RIPK2) inhibitor (IC50 of 5-10 nM). It inhibits NF-κB activity and decreases cancer cell proliferation by 70%. In vivo, RIPK2 inhibitor 1 inhibits intestinal and lung inflammation with low toxicity in rodent models.

Technical Data

M.Wt:
410.48
Formula:
C25H22N4O2
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
1290490-78-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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