Home / Cannabinoid R2/CB2 Agonists / RNB 61

RNB 61

Catalog #: 8835 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
8835/10

Save on RUO reagents! Up to 30% off + FREE shipping. See Details.

RNB 61 | CAS No. 1217403-51-4 | Cannabinoid R2/CB2 Agonists
1 Image
Description: Highly potent and selective CB2R agonist

Chemical Name: N-[(3E)-5-tert-Butyl-2-(cyclobutylmethyl)-1-methyl-1,2-dihydro-3H-pyrazol-3-ylidene]-2-(2-hydroxy-2-methylpropoxy)-5-(trifluoromethyl)benzamide

Purity: ≥97%

Product Details
Reviews
Biological Activity Technical Data Product Datasheets Calculators

Biological Activity

RNB 61 is a highly potent and selective cannabinoid CB2 receptor (CB2R) agonist (Ki = 0.57 nM). RNB 61 shows >5000-fold selectivity for hCB2R over hCB1R. In vivo, RNB 61 inhibits the FSK-induced cAMP formation on mouse, rat, and dog CB2Rs (EC50 values ranging from 0.13 to 1.86 nM). RNB 61 has a a peripherally restricted action and exerts a nephroprotective and/or antifibrotic effects in animal models of kidney disease.

Technical Data

M.Wt:
481.56
Formula:
C25H34F3N3O3
Solubility:
Soluble to 50 mM in DMSO and to 100 mM in ethanol
Purity:
≥97%
Storage:
Store at -20°C
CAS No:
1217403-51-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for RNB 61

There are currently no reviews for this product. Be the first to review RNB 61 and earn rewards!

Have you used RNB 61?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.