Home / Prostanoid Receptor Antagonists / Ro 1138452 hydrochloride

Ro 1138452 hydrochloride

Catalog #: 4268
1 Citation Datasheet / COA / SDS

Discontinued Product

4268 has been discontinued.
View all Prostanoid Receptor Antagonists products.
Ro 1138452 hydrochloride | Prostanoid Receptor Antagonists
1 Image
Description: Selective prostacyclin IP receptor antagonist

Chemical Name: 4,5-Dihydro-N-[4-[[4-(1-methylethoxy)phenyl]methyl]phenyl]-1H-imidazol-2-amine hydrochloride

Purity: ≥98%

Product Details
Citations (1)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Ro 1138452 hydrochloride is a selective prostacyclin IP receptor antagonist (pKi = 8.3). Exhibits no affinity at other prostanoid receptors (EP1-4, FP and TP) in a radioligand binding assay. Demonstrates analgesic activity in rats. Orally bioavailable.

Technical Data

M.Wt:
345.87
Formula:
C19H23N3O.HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
≥98%
Storage:
Desiccate at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citation for Ro 1138452 hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for Ro 1138452 hydrochloride include:

1 Citation: Showing 1 - 1

  1. Vascular Effects of Polyphenols from Agrimonia eupatoria L. and Role of Isoquercitrin in Its Vasorelaxant Potential in Human Arteries.
    Authors: Maria Dulce Et al.
    Pharmaceuticals (Basel)  2022;15

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for Ro 1138452 hydrochloride

There are currently no reviews for this product. Be the first to review Ro 1138452 hydrochloride and earn rewards!

Have you used Ro 1138452 hydrochloride?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.