RS 16566 dihydrochloride

Discontinued Product

1015 has been discontinued.
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RS 16566 dihydrochloride | CAS No. 1217788-97-0 | Additional 5-HT3 Receptor Compounds
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Description: 5-HT3 ligand; shows affinity for zacopride binding site

Chemical Name: (R)-N-1-Azabicyclo[2.2.2]oct-3-yl-6-chloro-1-(1-methylethyl)-1H-benzimidazole-4-carboxamide

Purity: ≥98%

Product Details
Citations (1)
Reviews

Biological Activity

RS 16566 dihydrochloride is a high affinity ligand for the (R)-zacopride binding site (pKi 9.84 ).

Technical Data

M.Wt:
419.78
Formula:
C18H23ClN4O.2HCl
Solubility:
Soluble to 10 mM in water
Purity:
≥98%
Storage:
Store at RT
CAS No:
1217788-97-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold with the permission of Roche Bioscience

Background References

  1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
    Fox JT, Sakamuru S, Huang R
    Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
  2. (R)-3-(6-Chloro-1-isopropylbenzimidazole-4-carboxamido)quinuclidine: a high affinity ligand for the (R)-zacopride binding site.
    Flippin et al.
    Bioorg.Med.Chem.Lett., 1996;6:477

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Citation for RS 16566 dihydrochloride

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