(RS)-PPG

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. Constitutive activity of metabotropic glutamate receptor 7.
   Kammermeier, Paul J
   BMC Neurosci, 2015;16(1):17.
2. Olanzapine: preclinical and clinical profiles of a novel antipsychotic agent.
   Tollefson and Taylor
   CNS Drug Reviews, 2000;6:303
3. Exploration of phenyl-spaced 2-amino-(5,9)-phosphonoalkanoic acids as competitive N-MthD.-aspartic acid antagonists.
   Bigge et al.
   J.Med.Chem., 1989;32:1580
4. (R,S)-4-Phosphonophenylglycine, a potent and selective group III metabotropic glutamate receptor agonist, is anticonvulsive and neuroprotective in vivo.
   Gasparini et al.
   J.Pharmacol.Exp.Ther., 1999;289:1678
5. Neuroprotection in vitro and in vivo by (R,S)-PPG, a potent and selective group III metabotropic glutamate receptor agonist.
   Flor et al.
   Soc.Neurosci.Abstr., 1998;24:431.11

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