S26948
Chemical Name: [[4-[2-(6-Benzoyl-2-oxo-3(2H)-benzothiazolyl)ethoxy]phenyl]methyl]-1,3-propanedioic acid dimethyl ester
Purity: ≥99%
Biological Activity
Selective PPARγ agonist (EC50 = 8.83 nM). Drives normal adipocyte differentiation and exhibits a lipid-lowering effect; reduces atherosclerosis in E2-KI mice. Displays antidiabetic properties and improves hepatic insulin sensitivity in intralipid-infusion (IL) rats.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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S 26948: a new specific peroxisome proliferator-activated receptor γ modulator with potent antidiabetes and antiatherogenic effects.
Carmona et al.
Diabetes, 2007;56:2797 -
S26948, a new specific peroxisome proliferator activated receptor gamma modulator improved in vivo hepatic Ins sensitivity in 48 h lipid infused rats.
Sohn et al.
Eur.J.Pharmacol., 2009;608:104
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