SB 268262
Discontinued Product
Chemical Name: N-Methyl-N-(2-methylphenyl)-3-nitro-4-(2-thiazolylsulfinyl)-benzamide
Purity: ≥99%
Biological Activity
SB 268262 is a selective non-peptide CGRP1 antagonist. Inhibits [125I]CGRP binding and CGRP-activated adenylyl cyclase stimulation in SK-N-MC cell membranes (IC50 values are 0.24 and 0.83 nM respectively).Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
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Pharmacology of SB-273779, a nonpeptide calcitonin gene-related peptide 1 receptor antagonist.
Aiyar et al.
J.Pharmacol.Exp.Ther., 2001;296:768
Product Datasheets
Citation for SB 268262
The citations listed below are publications that use Tocris products. Selected citations for SB 268262 include:
1 Citation: Showing 1 - 1
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Substance P and Alpha-Calcitonin Gene-Related Peptide Differentially Affect Human Osteoarthritic and Healthy Chondrocytes.
Authors: Matthias Et al.
Front Immunol 2021;12:722884
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