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Simple Plex Control for Human FGF-19

Catalog #: 898183 Datasheet / COA / SDS
Control for use with Human FGF-19 Simple Plex Cartridge Kit
Catalog # Availability Size / Price Qty
898183
Simple Plex Assay Controls
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Simple Plex Control for Human FGF-19 Summary

INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human FGF-19 concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.

Specifications

Source
N/A
Shipping Conditions
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Storage
• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.
Applications
Control Simple Plex Automated Immunoassay
Species
Human

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Product Datasheet

Background: FGF-19

FGF-19 (Fibroblast Growth Factor-19) is a secreted heparin-binding protein in the endocrine subfamily of FGFs that also includes FGF-21 and FGF-23. It is produced by epithelial cells of the ileal intestine in response to bile acids and signals through a receptor complex of FGF R4 and Klotho-beta in the liver. FGF-19 suppresses bile acid synthesis and enhances hepatic protein and glycogen synthesis. Dysregulalted FGF-19 activity is associated with the development of hypercholesterolemia, gall stones, bile acid induced diarrhoea (BAD), hepatocellular cancer, colon cancer, and metabolic syndrome.

Long Name
Fibroblast Growth Factor 19
Entrez Gene IDs
9965 (Human)
Alternate Names
FGF19; FGF-19; fibroblast growth factor 19

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