Simple Plex Control for Human MICA

Catalog #: 898141 Datasheet / COA / SDS

Control for use with Human MICA Simple Plex Cartridge Kit

Catalog #	Availability	Size / Price	Qty
898141

1 Image

All MICA Simple Plex Assays

Product Details

Supplemental Products

Reviews

Summary Product Datasheets Data Images Background

Simple Plex Control for Human MICA Summary

INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human MICA concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.

Specifications

Source

N/A

Shipping Conditions

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Storage

• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.

Applications

Control Simple Plex Automated Immunoassay

Species

Human

Product Datasheets

Product Datasheet

Background: MICA

MHC class I chain-related genes MICA and MICB are transmembrane glycoproteins that function as ligands for human NKG2D. The two proteins are highly related, sharing 85% amino acid identity, but are also polymorphic. Recognition of MICA or MICB by NKG2D results in the activation of NK cell cytolytic activity and/or cytokine production. MICA/B are minimally expressed on normal cells, but are frequently expressed on or shed from epithelial tumors and can be induced by bacterial and viral infections. MICA and MICB recognition is involved in tumor surveillance, viral infections, and autoimmune diseases.

Long Name

MHC Class I-related Protein A

Entrez Gene IDs

100507436 (Human)

Alternate Names

FLJ60820; MGC111087; MICA; PERB11.1