Simple Plex Human ASC Cartridge New

Catalog #: SPCKB-PS-003913 Datasheet / COA / SDS

Simple Plex Human ASC assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer

Catalog #	Availability	Size / Price	Qty
SPCKB-PS-003913
SPCKA-PS-003913
SPCKC-PS-003913

Control Products Available

898571: Simple Plex Control for Human ASC

All ASC Simple Plex Assays

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Summary Product Datasheets Preparation and Storage Background Related Research Areas

Simple Plex Human ASC Cartridge Summary

*The Sample Volume represented is based on the amount of sample incorporated into the reaction after taking into account the assay’s minimum required dilution for a given matrix. Serial dilution may be necessary to achieve some of the final sample volumes represented.

Product Summary

Product Datasheets

Product Datasheet

COA

SDS

Preparation and Storage

Storage

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: ASC

ASC contains an N-terminal Pyrin domain and C-terminal CARD (Caspase-recruitment Domain), and is a p53 target protein that serves as an adaptor to the pro-apoptotic Bax molecule. The interaction of ASC with Bax promotes apoptosis in response to many apoptotic stimuli. Methylation of the ASC gene has been correlated with decreased protein expression in numerous types of cancer.

Long Name:

Apoptosis-Associated Speck-Like Protein Containing A CARD

Entrez Gene IDs:

29108 (Human)

Alternate Names:

apoptosis-associated speck-like protein containing a CARD; ASC; CARD5; caspase recruitment domain protein 5; Caspase recruitment domain-containing protein 5; hASC; PYCARD; PYD and CARD domain-containing protein; Target of methylation-induced silencing 1; TMS; TMS1; TMS-1