Sulfo-NHS-LC-Biotin
Chemical Name: Sodium 2,5-dioxo-1-((6-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanoyl)oxy)pyrrolidine-3-sulfonate
Biological Activity
Sulfo-NHS-LC-Biotin is a water-soluble amine reactive biotinylation reagent used to attach biotin to primary amines. Commonly used to label proteins and antibodies. Does not penetrate membrane. Reactive in pH 7.0-9.0, solubility 10 mg/mL in water and DMF.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Long-term drug modification to the surface of mesenchymal stem cells by the avidin-biotin complex method.
Takayama et al.
Sci.Rep, 2017;7:16953 -
Multifunctional streptavidin-biotin conjugates with precise stoichiometries.
Xu and Wegner
Chem.Sci., 2020;11:4422 -
Butyrophilin-2A1 directly binds germline-encoded regions of the Vγ9Vδ2 TCR and is essential for phosphoantigen sensing.
Karunakaran et al.
Immunity, 2020;52:487
Product Datasheets
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Citation for Sulfo-NHS-LC-Biotin
The citations listed below are publications that use Tocris products. Selected citations for Sulfo-NHS-LC-Biotin include:
1 Citation: Showing 1 - 1
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Inflammation modulates intercellular adhesion and mechanotransduction in human epidermis via ROCK2.
Authors: Andrei I Et al.
iScience 2023;26:106195
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