TACS 2 TdT-DAB In Situ Apoptosis Detection Kit
TACS 2 TdT-DAB In Situ Apoptosis Detection Kit Summary
Provides a unique cation optimization system to enhance the in situ detection of apoptosis in a TUNEL based assay.Key Benefits
• TdT based in situ labeling.
• Cation optimization for high signal and low background.
• Complete kit providing DAB and Methyl Green Counterstain.
• Includes both Proteinase K and exclusive Cytonin non-enzymatic permeabilization reagent.
• Includes TACS-Nuclease control reagents.
Why Use the TACS 2 TdT-DAB In Situ Apoptosis Detection Kit?
The TACS 2 TdT DAB Kit utilizes a cation optimization system to enhance the in situ detection of apoptosis in a TUNEL based assay within fixed frozen, paraffin embedded, or plastic embedded cells and tissues. Enzymatic incorporation of biotinylated nucleotides in fragmented DNA is performed by a highly purified form of the TdT enzyme in a non-toxic labeling buffer (sodium cacodylate free). Biotin labeling is detected using streptavidin-horseradish peroxidase, and colorimetric substrates diaminobenzidine (DAB). Samples are counterstained with Methyl Green offering a nice contrast when visualized by light microscopy.
This complete kit provides all the reagents required for labeling including two permeabilization reagents, labeling and detection reagents, stop buffers, counterstain, and TACS-Nuclease reagents for generating positive controls with your own samples.
Product Specifications
- In situ detection of apoptosis by TUNEL-based assay in fixed frozen, paraffin embedded, or plastic embedded cells and tissues.
- Light microscopy.
Kit Contents
• Proteinase K
• Diaminobenzidine
• DAB Enhancer
• TACS-Nuclease
• TACS 2 TdT dNTP
• TdT Enzyme
• 50x Cobalt Cation
• 50x Magnesium Cation
• 50x Manganese Cation
• Streptavidin-HRP
• TACS-Nuclease™ Buffer
• Methyl Green 1%
• TACS 2 TdT Labeling Buffer
• TACS 2 TdT Stop Buffer
• Cytonin
Specifications
Limitations
For research use only. Not for diagnostic use.
Product Datasheets
Citations for TACS 2 TdT-DAB In Situ Apoptosis Detection Kit
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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HBS1L deficiency causes retinal dystrophy in a child and a mouse model associated with defective development of photoreceptor cells
Authors: Luo, S;Alwattar, B;Li, Q;Bora, K;Blomfield, AK;Lin, J;Fulton, A;Chen, J;Agrawal, PB;
Disease models & mechanisms 2024-07-05
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Dual blockade of interleukin-17A and interleukin-17F as a therapeutic strategy for liver fibrosis: Investigating the potential effect and mechanism of brodalumab
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Single-cell transcriptomics identifies the differentiation trajectory from inflammatory monocytes to pro-resolving macrophages in a mouse skin allergy model
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Nature communications 2024-02-23
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O-GlcNAc transferase promotes glioblastoma by modulating genes responsible for cell survival, invasion, and inflammation
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The Journal of biological chemistry 2023-09-07
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Inhibiting miR-195-5p Induces Proliferation of Human Corneal Endothelial Cells
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International journal of molecular sciences 2023-07-15
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Structural and functional integrity of endocrine pancreas post administration of Karwinskia humboldtiana fruit to Wistar rats: a possible therapeutic application for cancer of exocrine origin
Authors: JC Segoviano-, N Esparza-Ro, K Carcano-Di, RN Diaz-Perez, JP Palma-Nico, R Hernandez-, J Garcia-Jua
Histology and histopathology, 2023-03-02;0(0):18603. 2023-03-02
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Sirolimus-Embedded Silk Microneedle Wrap to Prevent Neointimal Hyperplasia in Vein Graft Model
Authors: JH Kim, EH Jang, JY Ryu, J Lee, JH Kim, W Ryu, YN Youn
International Journal of Molecular Sciences, 2023-02-07;24(4):. 2023-02-07
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Developing 3D Organoid Raft Cultures from Patient-Derived Xenografts as Rapid Models to Screen Efficacy of Experimental Therapeutics
Authors: P Bajpai, NS Banerjee, DW Moore, HG Kim, F Afaq, CM Contreras, MJ Heslin, VB Reddy, S Peter, S Varambally, S Al Diffalh, U Manne
International Journal of Molecular Sciences, 2022-11-19;23(22):. 2022-11-19
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Developmental basis of evolutionary lung loss in plethodontid salamanders
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Science Advances, 2022-08-17;8(33):eabo6108. 2022-08-17
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EGFR ligand shifts the role of EGFR from oncogene to tumour suppressor in EGFR-amplified glioblastoma by suppressing invasion through BIN3 upregulation
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Nature Cell Biology, 2022-08-01;24(8):1291-1305. 2022-08-01
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Saireito, a Japanese herbal medicine, alleviates leaky gut associated with antibiotic-induced dysbiosis in mice
Authors: S Ozaka, A Sonoda, S Ariki, M Minata, N Kamiyama, S Hidano, N Sachi, K Ito, Y Kudo, A Dewayani, T Chalalai, T Ozaki, Y Soga, C Fukuda, K Mizukami, S Ishizawa, M Nishiyama, N Fujitsuka, S Mogami, K Kubota, K Murakami, T Kobayashi
PLoS ONE, 2022-06-15;17(6):e0269698. 2022-06-15
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Implication of COPB2 Expression on Cutaneous Squamous Cell Carcinoma Pathogenesis
Authors: T Chen, KY Kim, Y Oh, HC Jeung, KY Chung, MR Roh, X Zhang
Cancers, 2022-04-18;14(8):. 2022-04-18
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Peroxiredoxin 3 deficiency induces cardiac hypertrophy and dysfunction by impaired mitochondrial quality control
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Redox Biology, 2022-02-28;51(0):102275. 2022-02-28
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MSK-Mediated Phosphorylation of Histone H3 Ser28 Couples MAPK Signalling with Early Gene Induction and Cardiac Hypertrophy
Authors: EL Robinson, FM Drawnel, S Mehdi, CR Archer, W Liu, H Okkenhaug, K Alkass, JM Aronsen, CK Nagaraju, I Sjaastad, KR Sipido, O Bergmann, JSC Arthur, X Wang, HL Roderick
Cells, 2022-02-09;11(4):. 2022-02-09
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Methodology and Neuromarkers for Cetaceans' Brains
Authors: S Sacchini, P Herráez, M Arbelo, A Espinosa d, E Sierra, M Rivero, C Bombardi, A Fernández
Veterinary sciences, 2022-01-21;9(2):. 2022-01-21
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Reduced hyaluronan cross-linking induces breast cancer malignancy in a CAF-dependent manner
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Cell Death & Disease, 2021-06-07;12(6):586. 2021-06-07
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CSF1R-dependent macrophages control postnatal somatic growth and organ maturation
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PloS Genetics, 2021-06-03;17(6):e1009605. 2021-06-03
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Islet Dysfunction in a Novel Transgenic Model of T Cell Insulitis
Authors: E Esakov, N Nandedkar-, AG Al-Dieri, H Hafner, B Gregg, MF McInerney
Biomolecules, 2021-04-09;11(4):. 2021-04-09
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SIRT6?specific inhibitor OSS?128167 exacerbates diabetic cardiomyopathy by aggravating inflammation and oxidative stress
Authors: Y Huang, J Zhang, D Xu, Y Peng, Y Jin, L Zhang
Molecular Medicine Reports, 2021-03-24;23(5):. 2021-03-24
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MTH1 and OGG1 maintain a low level of 8-oxoguanine in Alzheimer's brain, and prevent the progression of Alzheimer's pathogenesis
Authors: S Oka, J Leon, K Sakumi, N Abolhassan, Z Sheng, D Tsuchimoto, FM LaFerla, Y Nakabeppu
Scientific Reports, 2021-03-23;11(1):5819. 2021-03-23
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Remote effects and biodistribution of pulmonary instilled silver nanoparticles in mice
Authors: Z Ferdous, S Al-Salam, P Yuvaraju, BH Ali, A Nemmar
NanoImpact, 2021-03-13;22(0):100310. 2021-03-13
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Preferable Transplant Site for Hepatocyte Transplantation in a Rat Model
Authors: H Ogasawara, A Inagaki, I Fathi, T Imura, H Yamana, Y Saitoh, M Matsumura, K Fukuoka, S Miyagi, Y Nakamura, K Ohashi, M Unno, T Kamei, M Goto
Cell Transplantation, 2021-01-01;30(0):9636897211040. 2021-01-01
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Periadventitial Delivery of Simvastatin-Loaded Microparticles Attenuate Venous Neointimal Hyperplasia Associated With Arteriovenous Fistula
Authors: C Zhao, ST Zuckerman, C Cai, S Kilari, A Singh, M Simeon, HA von Recum, JN Korley, S Misra
Journal of the American Heart Association, 2020-12-05;9(24):e018418. 2020-12-05
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Mast4 knockout shows the regulation of spermatogonial stem cell self-renewal via the FGF2/ERM pathway
Authors: SJ Lee, J Park, DJ Lee, K Otsu, P Kim, S Mizuno, MJ Lee, HY Kim, H Harada, S Takahashi, SJ Kim, HS Jung
Cell Death Differ, 2020-11-20;0(0):. 2020-11-20
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Inhibition of NLRP3 inflammasome by MCC950 improves the metabolic outcome of islet transplantation by suppressing IL-1&beta and islet cellular death
Authors: T Matsuoka, G Yoshimatsu, N Sakata, R Kawakami, T Tanaka, T Yamada, Y Yoshida, S Hasegawa, S Kodama
Sci Rep, 2020-10-21;10(1):17920. 2020-10-21
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Spred2-deficiency enhances the proliferation of lung epithelial cells and alleviates pulmonary fibrosis induced by bleomycin
Authors: A Kawara, R Mizuta, M Fujisawa, T Ito, C Li, K Nakamura, C Sun, M Kuwabara, M Kitabatake, T Yoshimura, A Matsukawa
Sci Rep, 2020-10-05;10(1):16490. 2020-10-05
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NF-kappaB inhibitor with Temozolomide results in significant apoptosis in glioblastoma via the NF-kappaB(p65) and actin cytoskeleton regulatory pathways
Authors: NG Avci, S Ebrahimzad, YM Akay, Y Esquenazi, N Tandon, JJ Zhu, M Akay
Sci Rep, 2020-08-07;10(1):13352. 2020-08-07
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Compensatory combination of romidepsin with gemcitabine and cisplatin to effectively and safely control urothelial carcinoma
Authors: P Pattarawat, T Hong, S Wallace, Y Hu, R Donnell, TH Wang, CL Tsai, J Wang, HR Wang
Br. J. Cancer, 2020-05-11;0(0):. 2020-05-11
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Enhanced Biocompatibility of Multi-Layered, 3D Bio-Printed Artificial Vessels Composed of Autologous Mesenchymal Stem Cells
Authors: EH Jang, JH Kim, JH Lee, DH Kim, YN Youn
Polymers (Basel), 2020-03-02;12(3):. 2020-03-02
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Endothelial autophagy deficiency induces IL6 - dependent endothelial mesenchymal transition and organ fibrosis
Authors: Y Takagaki, SM Lee, Z Dongqing, M Kitada, K Kanasaki, D Koya
Autophagy, 2020-01-22;0(0):1-10. 2020-01-22
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Targeting alkaline ceramidase 3 alleviates the severity of nonalcoholic steatohepatitis by reducing oxidative stress
Authors: K Wang, C Li, X Lin, H Sun, R Xu, Q Li, Y Wei, Y Li, J Qian, C Liu, Q Zhang, S Yu, Z Cui, X Huang, B Zhu, J Zhou, C Mao
Cell Death Dis, 2020-01-16;11(1):28. 2020-01-16
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Ginsenoside CK induces apoptosis and suppresses proliferation and invasion of human osteosarcoma cells through the PI3K/mTOR/p70S6K1 pathway
Authors: K Chen, J Jiao, J Xue, T Chen, Y Hou, Y Jiang, L Qian, Y Wang, Z Ma, Z Liang, B Sun, Q Ren
Oncol. Rep., 2020-01-13;43(3):886-896. 2020-01-13
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Inhibitor of DNA-Binding Protein 4 Suppresses Cancer Metastasis through the Regulation of Epithelial Mesenchymal Transition in Lung Adenocarcinoma
Authors: CC Wang, YL Hsu, CJ Chang, CJ Wang, TH Hsiao, SH Pan
Cancers (Basel), 2019-12-14;11(12):. 2019-12-14
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Attenuation of diabetic cardiomyopathy by relying on kirenol to suppress inflammation in a diabetic rat model
Authors: B Wu, XY Huang, L Li, XH Fan, PC Li, CQ Huang, J Xiao, R Gui, S Wang
J. Cell. Mol. Med., 2019-09-29;0(0):. 2019-09-29
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Triptolide sensitizes cisplatin-resistant human epithelial ovarian cancer by inhibiting the phosphorylation of AKT
Authors: G Huang, H Hu, Y Zhang, Y Zhu, J Liu, B Tan, T Chen
J Cancer, 2019-06-02;10(13):3012-3020. 2019-06-02
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VEGF-A from Granuloma Macrophages Regulates Granulomatous Inflammation by a Non-angiogenic Pathway during Mycobacterial Infection
Authors: JS Harding, M Herbath, Y Chen, A Rayasam, A Ritter, B Csoka, G Hasko, IP Michael, Z Fabry, A Nagy, M Sandor
Cell Rep, 2019-05-14;27(7):2119-2131.e6. 2019-05-14
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8-Oxoguanine accumulation in aged female brain impairs neurogenesis in the dentate gyrus and major island of Calleja, causing sexually dimorphic phenotypes
Authors: N Haruyama, K Sakumi, A Katogi, D Tsuchimoto, G De Luca, M Bignami, Y Nakabeppu
Prog. Neurobiol., 2019-04-23;0(0):. 2019-04-23
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A Simple and Useful Predictive Assay for Evaluating the Quality of Isolated Hepatocytes for Hepatocyte Transplantation
Authors: M Matsumura, T Imura, A Inagaki, H Ogasawara, K Fukuoka, I Fathi, S Miyagi, K Ohashi, M Unno, T Kamei, S Satomi, M Goto
Sci Rep, 2019-04-16;9(1):6166. 2019-04-16
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Concomitant Inhibition of Cytoprotective Autophagy Augments the Efficacy of Withaferin A in Hepatocellular Carcinoma
Authors: S Siddharth, N Muniraj, NK Saxena, D Sharma
Cancers (Basel), 2019-03-30;11(4):. 2019-03-30
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Epithelial ovarian cancer: feasibility of image-guided intratumoral radiofrequency hyperthermia-enhanced direct gene therapy
Authors: G Jin, Y Li, F Zhang, P Li, L Zhao, Y Zhou, H Ji, S Pietrini, B Zhai, X Yang
Am J Cancer Res, 2019-02-01;9(2):378-389. 2019-02-01
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Impaired LXR? Phosphorylation Attenuates Progression of Fatty Liver Disease
Authors: N Becares, MC Gage, M Voisin, E Shrestha, L Martin-Gut, N Liang, R Louie, B Pourcet, OM Pello, TV Luong, S Goñi, C Pichardo-A, H Røberg-Lar, V Diaz-Zucca, KR Steffensen, A O'Brien, MJ Garabedian, K Rombouts, E Treuter, I Pineda-Tor
Cell Rep, 2019-01-22;26(4):984-995.e6. 2019-01-22
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Zika virus infection at mid-gestation results in fetal cerebral cortical injury and fetal death in the olive baboon
Authors: S Gurung, N Reuter, A Preno, J Dubaut, H Nadeau, K Hyatt, K Singleton, A Martin, WT Parks, JF Papin, DA Myers
PLoS Pathog., 2019-01-18;15(1):e1007507. 2019-01-18
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MiR-30c/PGC-1? protects against diabetic cardiomyopathy via PPAR?
Authors: Z Yin, Y Zhao, M He, H Li, J Fan, X Nie, M Yan, C Chen, DW Wang
Cardiovasc Diabetol, 2019-01-11;18(1):7. 2019-01-11
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Schwannoma gene therapy by adeno-associated virus delivery of the pore-forming protein Gasdermin-D
Authors: SG Ahmed, A Ahmed, M Doha, GJ Brenner
Cancer Gene Ther., 2019-01-09;0(0):. 2019-01-09
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Human neural stem cell-derived neuron/astrocyte co-cultures respond to La Crosse virus infection with proinflammatory cytokines and chemokines
Authors: BE Dawes, J Gao, C Atkins, JT Nelson, K Johnson, P Wu, AN Freiberg
J Neuroinflammation, 2018-11-15;15(1):315. 2018-11-15
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Role of SIRT2 in Regulation of Stemness of Cancer Stem-Like Cells in Renal Cell Carcinoma
Authors: R Wei, D He, X Zhang
Cell. Physiol. Biochem., 2018-09-27;49(6):2348-2357. 2018-09-27
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RIPK3 promotes sepsis-induced acute kidney injury via mitochondrial dysfunction
Authors: A Sureshbabu, E Patino, KC Ma, K Laursen, EJ Finkelszte, O Akchurin, T Muthukumar, SW Ryter, L Gudas, AMK Choi, ME Choi
JCI Insight, 2018-06-07;3(11):. 2018-06-07
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Cardioprotective Effects of QiShenYiQi Dripping Pills on Transverse Aortic Constriction-Induced Heart Failure in Mice
Authors: G Ruan, H Ren, C Zhang, X Zhu, C Xu, L Wang
Front Physiol, 2018-04-03;9(0):324. 2018-04-03
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Treatment of Arsenite Intoxication-Induced Peripheral Vasculopathy with Mesenchymal Stem Cells
Authors: YH Chiang, CC Lin, YC Chen, OK Lee
Int J Mol Sci, 2018-03-29;19(4):. 2018-03-29
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Concomitant modulation of PTEN and Livin in gastric cancer treatment
Authors: CL Zhao, SN Han, ZJ Wang, SH Wang, GQ Zhao, XF Zhang, JX Wang
Int. J. Mol. Med., 2018-02-08;0(0):. 2018-02-08
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Serum vitamin C levels modulate the lifespan and endoplasmic reticulum stress response pathways in mice synthesizing a nonfunctional mutant WRN protein
Authors: L Aumailley, MJ Dubois, TA Brennan, C Garand, ER Paquet, RJ Pignolo, A Marette, M Lebel
FASEB J., 2018-02-08;0(0):fj201701176R. 2018-02-08
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X-linked inhibitor of apoptosis inhibition sensitizes acute myeloid leukemia cell response to TRAIL and chemotherapy through potentiated induction of proapoptotic machinery
Authors: J Zhou, X Lu, TZ Tan, WJ Chng
Mol Oncol, 2017-12-01;12(1):33-47. 2017-12-01
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Histone demethylase PHF8 accelerates the progression of colorectal cancer and can be regulated by miR-488 in�vitro
Authors: Y Lv, Y Shi, Q Han, G Dai
Mol Med Rep, 2017-08-01;16(4):4437-4444. 2017-08-01
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Cryopreservation Method for the Effective Collection of Dental Pulp Stem Cells.
Authors: Takebe Y, Tatehara S, Fukushima T, Tokuyama-Toda R, Yasuhara R, Mishima K, Satomura K
Tissue Eng Part C Methods, 2017-05-01;23(5):251-261. 2017-05-01
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Influence of long-term, high-dose dexamethasone administration on proliferation and apoptosis in porcine hepatocytes
Authors: M Mikiewicz, I Otrocka-Do, K Pa?dzior-C, T Rotkiewicz
Res. Vet. Sci., 2017-04-02;112(0):141-148. 2017-04-02
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Chronic PARP-1 inhibition reduces carotid vessel remodeling and oxidative damage of the dorsal hippocampus in spontaneously hypertensive rats
Authors: K Eros, K Magyar, L Deres, A Skazel, A Riba, Z Vamos, T Kalai, F Gallyas, B Sumegi, K Toth, R Halmosi
PLoS ONE, 2017-03-24;12(3):e0174401. 2017-03-24
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ENOblock, a unique small molecule inhibitor of the non-glycolytic functions of enolase, alleviates the symptoms of type 2 diabetes.
Authors: Cho H, Um J, Lee J, Kim W, Kang W, Kim S, Ha H, Kim Y, Ahn Y, Jung D, Williams D
Sci Rep, 2017-03-08;7(0):44186. 2017-03-08
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Regulation of Sirtuin 3-Mediated Deacetylation of Cyclophilin D Attenuated Cognitive Dysfunction Induced by Sepsis-Associated Encephalopathy in Mice.
Authors: Sun F, Si Y, Bao H, Xu Y, Pan X, Zeng L, Jing L
Cell Mol Neurobiol, 2017-02-25;37(8):1457-1464. 2017-02-25
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Calcium-dependent enhancement by extracellular acidity of the cytotoxicity of mitochondrial inhibitors against melanoma
Authors: F Noguchi, S Inui, C Fedele, M Shackleton, S Itami
Mol. Cancer Ther, 2017-02-21;0(0):. 2017-02-21
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PERK Is a Haploinsufficient Tumor Suppressor: Gene Dose Determines Tumor-Suppressive Versus Tumor Promoting Properties of PERK in Melanoma
PLoS Genet, 2016-12-15;12(12):e1006518. 2016-12-15
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Differential cell-matrix responses in hypoxia-stimulated aortic versus mitral valves.
Authors: Sapp M, Krishnamurthy V, Puperi D, Bhatnagar S, Fatora G, Mutyala N, Grande-Allen K
J R Soc Interface, 2016-12-01;13(125):. 2016-12-01
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Smpd3 Expression in both Chondrocytes and Osteoblasts Is Required for Normal Endochondral Bone Development.
Authors: Li J, Manickam G, Ray S, Oh C, Yasuda H, Moffatt P, Murshed M
Mol Cell Biol, 2016-08-12;36(17):2282-99. 2016-08-12
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Chromatin assembly factor 1, subunit A (P150) facilitates cell proliferation in human hepatocellular carcinoma
Onco Targets Ther, 2016-07-01;9(0):4023-35. 2016-07-01
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TLR4 Deficiency Impairs Oligodendrocyte Formation in the Injured Spinal Cord.
Authors: Church J, Kigerl K, Lerch J, Popovich P, McTigue D
J Neurosci, 2016-06-08;36(23):6352-64. 2016-06-08
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mTORC1-Driven Tumor Cells Are Highly Sensitive to Therapeutic Targeting by Antagonists of Oxidative Stress.
Authors: Li J, Shin S, Sun Y, Yoon S, Li C, Zhang E, Yu J, Zhang J, Blenis J
Cancer Res, 2016-05-17;76(16):4816-27. 2016-05-17
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Uterine natural killer cell partnerships in early mouse decidua basalis.
Authors: Felker A, Croy B
J Leukoc Biol, 2016-03-21;100(4):645-655. 2016-03-21
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Transient increase of fractional anisotropy in reversible vasogenic edema.
Authors: Kimura-Ohba S, Yang Y, Thompson J, Kimura T, Salayandia V, Cosse M, Yang Y, Sillerud L, Rosenberg G
J Cereb Blood Flow Metab, 2016-02-10;36(10):1731-1743. 2016-02-10
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Targeted Deletion of p53 in Lgr5-Expressing Intestinal Stem Cells Promotes Colon Tumorigenesis in a Preclinical Model of Colitis-Associated Cancer.
Authors: Davidson L, Callaway E, Kim E, Weeks B, Fan Y, Allred C, Chapkin R
Cancer Res, 2015-12-02;75(24):5392-7. 2015-12-02
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Granzyme B Deficiency Protects against Angiotensin II-Induced Cardiac Fibrosis.
Authors: Shen Y, Cheng F, Sharma M, Merkulova Y, Raithatha S, Parkinson L, Zhao H, Westendorf K, Bohunek L, Bozin T, Hsu I, Ang L, Williams S, Bleackley R, Eriksson J, Seidman M, McManus B, Granville D
Am J Pathol, 2015-11-25;186(1):87-100. 2015-11-25
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Acceleration of diabetic wound healing using a novel protease-anti-protease combination therapy.
Authors: Gao M, Nguyen T, Suckow M, Wolter W, Gooyit M, Mobashery S, Chang M
Proc Natl Acad Sci U S A, 2015-11-23;112(49):15226-31. 2015-11-23
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Folate Receptor-Targeted Polymeric Micellar Nanocarriers for Delivery of Orlistat as a Repurposed Drug against Triple-Negative Breast Cancer.
Authors: Paulmurugan R, Bhethanabotla R, Mishra K, Devulapally R, Foygel K, Sekar T, Ananta J, Massoud T, Joy A
Mol Cancer Ther, 2015-11-09;15(2):221-31. 2015-11-09
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Secreted Frizzled-Related Protein 3 (SFRP3) Is Required for Tumorigenesis of PAX3-FOXO1-Positive Alveolar Rhabdomyosarcoma.
Authors: Kephart J, Tiller R, Crose L, Slemmons K, Chen P, Hinson A, Bentley R, Chi J, Linardic C
Clin Cancer Res, 2015-06-12;21(21):4868-80. 2015-06-12
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Distinct Immune Responses in Resistant and Susceptible Strains of Mice during Neurovirulent Alphavirus Encephalomyelitis.
Authors: Kulcsar K, Baxter V, Abraham R, Nelson A, Griffin D
J Virol, 2015-06-03;89(16):8280-91. 2015-06-03
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The endogenous cell-fate factor dachshund restrains prostate epithelial cell migration via repression of cytokine secretion via a cxcl signaling module.
Authors: Chen K, Wu K, Jiao X, Wang L, Ju X, Wang M, Di Sante G, Xu S, Wang Q, Li K, Sun X, Xu C, Li Z, Casimiro M, Ertel A, Addya S, McCue P, Lisanti M, Wang C, Davis R, Mardon G, Pestell R
Cancer Res, 2015-03-13;75(10):1992-2004. 2015-03-13
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Neonatal uterine and vaginal cell proliferation and adenogenesis are independent of estrogen receptor 1 (ESR1) in the mouse.
Authors: Nanjappa M, Medrano T, March A, Cooke P
Biol Reprod, 2015-02-04;92(3):78. 2015-02-04
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FBXW7 acts as an independent prognostic marker and inhibits tumor growth in human osteosarcoma.
Authors: Li, Zhanchun, Xiao, Jie, Hu, Kongzu, Wang, Gang, Li, Maoqiang, Zhang, Jidong, Cheng, Guangqi
Int J Mol Sci, 2015-01-22;16(2):2294-306. 2015-01-22
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Synthetic lethality of combined glutaminase and Hsp90 inhibition in mTORC1-driven tumor cells.
Authors: Li J, Csibi A, Yang S, Hoffman G, Li C, Zhang E, Yu J, Blenis J
Proc Natl Acad Sci U S A, 2014-12-18;112(1):E21-9. 2014-12-18
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PTH1-34 blocks radiation-induced osteoblast apoptosis by enhancing DNA repair through canonical Wnt pathway.
Authors: Chandra A, Lin T, Zhu J, Tong W, Huo Y, Jia H, Zhang Y, Liu X, Cengel K, Xia B, Qin L
J Biol Chem, 2014-10-21;290(1):157-67. 2014-10-21
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Intestinal myofibroblast-specific Tpl2-Cox-2-PGE2 pathway links innate sensing to epithelial homeostasis.
Authors: Roulis M, Nikolaou C, Kotsaki E, Kaffe E, Karagianni N, Koliaraki V, Salpea K, Ragoussis J, Aidinis V, Martini E, Becker C, Herschman H, Vetrano S, Danese S, Kollias G
Proc Natl Acad Sci U S A, 2014-10-14;111(43):E4658-67. 2014-10-14
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