Taxol Janelia Fluor® 526
Chemical Name: 4-((8-(((1S,2R)-3-(((2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-Acetoxy-12-(benzoyloxy)-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-9-yl)oxy)-2-hydroxy-3-oxo-1-phenylpropyl)amino)-8-oxooctyl)carbamoyl)-2-(3-(3,3-difluoroazetidin-1-ium-1-ylidene)-6-(3,3-difluoroazetidin-1-yl)-2,7-difluoro-3H-xanthen-9-yl)benzoate trifluoroacetate
Purity: ≥85%
Biological Activity
Key information: Taxol Janelia Fluor® 526 is a fluorogenic, green-fluorescent taxol derivative for direct imaging of the microtubule cytoskeleton. Suitable for live cell imaging.Used for: direct imaging of the microtubule cytoskeleton.
Application: confocal microscopy, Super Resolution Microscopy (SRM) including STED.
Properties and Photophysical Data: Taxol Janelia Fluor® 526 is fluorogenic: it fluoresces only once bound to microtubules, enabling hassle-free no-wash experiments. Excitation and emission maxima (λ) are 531 nm and 549 nm, respectively; quantum yield = 0.87; extinction coefficient = 118,000 M-1cm-1.
Optical Data for Taxol Janelia Fluor® 526
| Emission Color | Yellow |
|---|---|
| λabs | 531 nm |
| λem | 549 nm |
| Extinction Coefficient (ε) | 118000 M-1cm-1 |
| Quantum Yield (φ) | 0.87 |
| Application | Confocal Microscopy, Super Resolution Microscopy (SRM), STED |
Plan Your Experiments
Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.
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Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
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Rational design of fluorogenic and spontaneously blinking labels for super-resolution imaging.
Zheng et al.
ACS Cent.Sci., 2019;5:1602
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