Home / Microtubule Probes / Taxol Janelia Fluor® 646

Taxol Janelia Fluor® 646

Catalog #: 6266
2 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
6266/1
Taxol Janelia Fluor® 646 | Microtubule Probes
2 Images
Description: Red-fluorescent taxol derivative. Used for: microtubule staining. Application: confocal microscopy, fluorescence microscopy; protocol available

Chemical Name: 2-(3-(Azetidin-1-ium-1-ylidene)-7-(azetidin-1-yl)-5,5-dimethyl-3,5-dihydrodibenzo[b,e]silin-10-yl)-4-(((2S)-1-(((2aR,4S,4aS,6R,9S,11S,12S,12bS)-6,12b-diacetoxy-9-(((2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl)oxy)-12-(benzoyloxy)-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-4-yl)oxy)-1-oxopropan-2-yl)carbamoyl)benzoate

Purity: ≥95%

Product Details
Citations (2)
Reviews
Biological Activity Scientific Data Technical Data Additional Information Product Datasheets Calculators

Biological Activity

Key information: Taxol Janelia Fluor® 646 is a red-fluorescent taxol derivative for direct imaging of the microtubule cytoskeleton.

Used for: microtubule cytoskeleton imaging.

Application: confocal microscopy, fluorescence microscopy.

Properties and Photophysical Data: Excitation and emission maxima (λ) are 655 nm and 671 nm, respectively.

For more information on how Taxol-Janelia Fluor® 646 may be used, see our protocol.

Scientific Data

Confocal Microscopy COS7 cells dye-labeled with Taxol Janelia Fluor 646 View Larger

Application of Taxol Janelia Fluor® 646, dye on COS7 cells. COS7 cells were labeled with 3 µM Taxol Janelia Fluor® 646 for one hour at 37°C. Images were taken on a Leica TCS SP8 Confocal Laser Scanning Microscope. All images kindly provided by Prof. Christian Soeller, University of Exeter; acquired by Evelina Lucinskaite, Anna Meletiou and Alexander Clowsley.

Optical Data for Taxol Janelia Fluor® 646

Taxol Janelia Fluor<sup>®</sup> 646 Dye Spectra
Emission Color Red
λabs 655 nm
λem 671 nm
Application Fluorescence Microscopy, Confocal Microscopy

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

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Technical Data

M.Wt:
1403.62
Formula:
C79H82N4O18Si
Solubility:
Soluble to 20 mM in DMSO
Purity:
≥95%
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus

Product Datasheets

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Reconstitution Calculator

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Citations for Taxol Janelia Fluor® 646

The citations listed below are publications that use Tocris products. Selected citations for Taxol Janelia Fluor® 646 include:

2 Citations: Showing 1 - 2

  1. Optical blood-brain-tumor barrier modulation expands therapeutic options for glioblastoma treatment.
    Authors: Cai Et al.
    Nat.Commun.  2023;14:4934
  2. Capturing T lymphocytes' dynamic interactions with human neural cells using time-lapse microscopy.
    Authors: Lema&#238;tre Et al.
    Front.Immunol.  2021;12

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