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Thalidomide 4'-ether-PEG5-amine

Catalog #: 6951 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
6951/25
Thalidomide 4'-ether-PEG5-amine | CAS No. 2341841-01-6 | Degrader Building Blocks
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Description: Cereblon ligand with PEG linker and terminal amine for onward chemistry
Alternative Names: Thalidomide - linker 12

Chemical Name: 4-((17-Amino-3,6,9,12,15-pentaoxaheptadecyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride

Purity: ≥95%

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Biological Activity

Thalidomide 4'-ether-PEG5-amine is a functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus a PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

This product has been recently renamed. The previous name for this product was Thalidomide - linker 12

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data

M.Wt:
574.02
Formula:
C25H35N3O10.HCl
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
2341841-01-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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