Tocriscreen 2.0 Mini
Biological Activity
Tocriscreen 2.0 Mini is a library of 1280 biologically active compounds from the Tocris catalog. Covers a wide range of pharmacological targets and research areas. Compounds are supplied pre-dissolved in 50 μL 10 mM DMSO solutions.This library replaces the Tocriscreen Plus Mini (Cat. No. 5841).
For more information on the Tocriscreen 2.0 Compound Libraries, please download our informative flyer.
If this library does not suit your needs, please submit your requirements through our Tocriscreen PRO custom compound library service.
Key Format and Product Details
- 96-well racks with Matrix storage tubes & SepraSeal caps
- Compounds arranged 80 per rack with 16 racks per library
- Pre-dissolved in DMSO
- Many compounds are exclusive to Tocris
- Unique library with low overlap
- Full chemical and biological data available
- Exceptional purity
The Tocriscreen 2.0 Compound Library contains bioactive compounds covering a diverse range of molecular targets; 7-TM receptors (GPCRs; 27%), non-kinase enzymes (21%), kinases including enzyme-linked receptors (20%), ion channels (13%), cell biology targets (9%), nuclear receptors (6%), and transporters and other pharmacological targets (5%).
Request Compound List
A list of the compounds available in the Tocriscreen 2.0 Mini can be requested in Excel or SD format via our Tocriscreen & Custom Library Inquiries form.
Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
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Cell-based potassium ion channel screening using the FluxORTM assay.
Beacham et al.
J.Biomol.Screen., 2010;15:44 -
Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules.
Li et al.
Cell Research, 2011;21:196 -
Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis.
Hattori et al.
Proc.Natl.Acad.Sci.USA, 2010;107:3546 -
Small-molecule-driven direct reprogramming of mouse fibroblasts into functional neurons.
Li et al.
Cell Stem Cell, 2015;17:195 -
Small molecules enhance CRISPR genome editing in pluripotent stem cells.
Yu et al.
Cell Stem Cell, 2015;16:142
Product Datasheets
Reconstitution Calculator
Citations for Tocriscreen 2.0 Mini
The citations listed below are publications that use Tocris products. Selected citations for Tocriscreen 2.0 Mini include:
19 Citations: Showing 1 - 10
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Multivariate chemogenomic screening prioritizes new macrofilaricidal leads.
Authors: Wheeler Et al.
Commun.Biol. 2023;6:44
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Screening for small molecule inhibitors of SAH nucleosidase using an SAH riboswitch.
Authors: Sadeeshkumar Et al.
Anal.Biochem. 2023;666:115047
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Prolonged estrogen deprivation triggers a broad immunosuppressive phenotype in breast cancer cells.
Authors: Hühn Et al.
Mol Oncol 2022;16:148
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Prolonged estrogen deprivation triggers a broad immunosuppressive phenotype in breast cancer cells.
Authors: H?hn Et al.
Mol.Oncol. 2022;16:148
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Screening of chemical libraries using xenopus embryos and tadpoles for phenotypic drug discovery.
Authors: Gull Et al.
Cold Spring Harb.Protoc. 2022;
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Antiviral activity of CD437 against mumps virus.
Authors: Kato Et al.
Front.Microbiol. 2021;12:751909
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A chemical screen for modulators of mRNA translation identifies a distinct mechanism of toxicity for sphingosine kinase inhibitors
Authors: Corman Et al.
PLoS Biol 2021;
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HIV-1 fusion inhibitors targeting the membrane-proximal external region of Env spikes.
Authors: Xiao Et al.
Nat.Chem.Biol. 2020;16:529
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Induced pluripotent stem cell-derived monocytic cell lines from a NOMID patient serve as a screening platform for modulating NLRP3 inflammasome activity.
Authors: Seki Et al.
PLoS One 2020;15:e0237030
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A FRET-based high-throughput screening platform for the discovery of chemical probes targeting the scaffolding functions of human tankyrases.
Authors: Sowa Et al.
Sci Rep 2020;10:12357
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A Chemical Screen Identifies Compounds Limiting the Toxicity of C9ORF72 Dipeptide Repeats
Authors: Corman Et al.
Cell Chem Biol 2019;26:235
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Identification of inhibitors of dengue viral replication using replicon cells expressing secretory luciferase.
Authors: Kato Et al.
Antiviral.Res. 2019;172:104643
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BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr348 phosphorylation.
Authors: Sartori Et al.
Acta Neuropathol 2019;138:631
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An image-based small-molecule screen identifies vimentin as a pharmacologically relevant target of SimV. in cancer cells.
Authors: Trogden Et al.
FASEB J 2018;32:2841
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Hypothalamic regulation of regionally distinct adult neural stem cells and neurogenesis.
Authors: Paul Et al.
Science 2017;356:1383
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A small-molecule screen reveals that HSP90� promotes the conversion of induced pluripotent stem cell-derived endoderm to a hepatic fate and regulates HNF4A turnover.
Authors: Jing Et al.
Development 2017;144:1764
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Screening for novel LRRK2 inhibitors using a high-throughput TR-FRET cellular assay for LRRK2 Ser935 phosphorylation.
Authors: Hermanson Et al.
PLoS One 2012;7:e43580
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A GPR40 agonist GW9508 suppresses CCL5, CCL17, and CXCL10 induction in keratinocytes and attenuates cutaneous immune inflammation.
Authors: Fujita Et al.
J Invest Dermatol 2011;131:1660
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Cell-based potassium ion channel screening using the FluxOR assay.
Authors: Beacham Et al.
J.Biomol.Screen. 2010;15:441
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