Tracazolate hydrochloride
Chemical Name: 4-(Butylamino)-1-ethyl-6-methyl 1H-pyrazolo[3,4b]pyridine-5-ethylcarboxylate hydrochloride
Purity: ≥99%
Biological Activity
Tracazolate hydrochloride is a GABAA receptor modulator. Can potentiate or inhibit recombinant GABAA function depending on subunit combination. Enhances native GABAA receptor function and is anxiolytic following systemic administration in vivo.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Enhancement of benzodiazepine and GABA binding by the novel anxiolytic, tracazolate.
Meiners and Salama
Eur.J.Pharmacol., 1982;78:315 -
Pharmacological properties of tracazolate: a new non-benzodiazepine anxiolytic agent.
Patel and Malick
Eur.J.Pharmacol., 1982;78:323 -
Tracazolate reveals a novel type of allosteric interaction with recombinant γ-aminobutyric acidA receptors.
Thompson et al.
Mol.Pharmacol., 2002;61:861
Product Datasheets
Reconstitution Calculator
Molarity Calculator
Citation for Tracazolate hydrochloride
The citations listed below are publications that use Tocris products. Selected citations for Tracazolate hydrochloride include:
1 Citation: Showing 1 - 1
-
Synaptic GABAA receptor clustering without the γ2 subunit.
Authors: Kerti-Szigeti Et al.
J Neurosci 2014;34:10219
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsReviews for Tracazolate hydrochloride
There are currently no reviews for this product. Be the first to review Tracazolate hydrochloride and earn rewards!
Have you used Tracazolate hydrochloride?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
