trans-4-Hydroxycrotonic acid

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
   Fox JT, Sakamuru S, Huang R
   Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
2. Analogues of γ-hydroxybutyric acid. Synthesis and binding studies.
   Bourguignon et al.
   J.Med.Chem., 1988;31:893
3. Gamma hydroxybutyrate ligands posses antiDArgic and neuroleptic-like activities.
   Hechler et al.
   J.Pharmacol.Exp.Ther., 1993;264:1406
4. Natural occurrence of trans-gamma hydroxycrotonic acid in rat brain.
   Vayer et al.
   Biochem.Pharmacol., 1985;34:2401

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