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UNC 2400

Catalog #: 4905
1 Citation Datasheet / COA / SDS

Discontinued Product

4905 has been discontinued.
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UNC 2400 | CAS No. 1433200-49-7 | EZH2 Inhibitor
1 Image
Description: Negative control of UNC 1999 (Cat. No. 4904)

Chemical Name: N-[(1,2-Dihydro-1,6-dimethyl-2-oxo-4-propyl-3-pyridinyl)methyl]-N-methyl-1-(1-methylethyl)-6-[6-[4-(1-methylethyl)-1-piperazinyl]-3-pyridinyl]-1H-indazole-4-carboxamide

Purity: ≥98%

Product Details
Citations (1)
Reviews
Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

UNC 2400 is a negative control of UNC 1999. Exhibits 1000-fold lower potency than active analog (IC50 values are 62 and >200 μM for EZH1 and EZH2, respectively).

Active Analog also available.

Technical Data

M.Wt:
597.79
Formula:
C35H47N7O2
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in 1eq. HCl
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
1433200-49-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
This compound is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the UNC 1999 probe summary on the SGC website.
Other Product-Specific Information:

Product Datasheets

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Citation for UNC 2400

The citations listed below are publications that use Tocris products. Selected citations for UNC 2400 include:

1 Citation: Showing 1 - 1

  1. SCL/TAL1 cooperates with Polycomb RYBP-PRC1 to suppress alternative lineages in blood-fated cells.
    Authors: Chagraoui Et al.
    Nat Commun  2018;9:5375

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