Home / 5-HT Transporter Inhibitors / Venlafaxine hydrochloride

Venlafaxine hydrochloride

Catalog #: 2917
3 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
2917/10
2917/50
Venlafaxine hydrochloride | CAS No. 99300-78-4 | 5-HT Transporter Inhibitors
1 Image
Description: 5-HT and NA reuptake inhibitor (SNRI)
Alternative Names: Wy 45030

Chemical Name: 1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol hydrochloride

Purity: ≥99%

Product Details
Citations (3)
Supplemental Products
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Venlafaxine hydrochloride is a dual serotonin/noradrenalin re-uptake inhibitor that displays ~ 30-fold higher affinity for SERT than NET (Ki values are 82 and 2480 nM respectively). Antidepressant; increases swimming and climbing behavior in the forced-swim test in rats.

Technical Data

M.Wt:
313.86
Formula:
C17H27NO2.HCl
Solubility:
Soluble to 100 mM in water and to 50 mM in DMSO
Purity:
≥99%
Storage:
Store at RT
CAS No:
99300-78-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citations for Venlafaxine hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for Venlafaxine hydrochloride include:

3 Citations: Showing 1 - 3

  1. Distinct Neuropsychological Mechanisms May Explain Delayed- Versus Rapid-Onset Antidepressant Efficacy.
    Authors: Stuart Et al.
    Proc Natl Acad Sci U S A  2015;40:2165
  2. Synergistic regulation of glutamatergic transmission by serotonin and NE reuptake inhibitors in prefrontal cortical neurons.
    Authors: Yuen Et al.
    J Biol Chem  2014;289:25177
  3. A translational rodent assay of affective biases in depression and antidepressant therapy.
    Authors: Stuart Et al.
    Neuropsychopharmacology  2013;38:1625

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for Venlafaxine hydrochloride

There are currently no reviews for this product. Be the first to review Venlafaxine hydrochloride and earn rewards!

Have you used Venlafaxine hydrochloride?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.