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VH 101 phenol-alkylC6-amine

Catalog #: 7294 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
7294/25
VH 101 phenol-alkylC6-amine | CAS No. 2564467-16-7 | Degrader Building Blocks
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Description: VHL ligand with alkyl linker and terminal amine for onward chemistry

Chemical Name: (2S,4R)-N-(2-((6-Aminohexyl)oxy)-4-(4-methylthiazol-5-yl)benzyl)-1-((S)-2-(1-fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide dihydrochloride

Purity: ≥95%

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Biological Activity

VH 101 phenol-alkylC6-amine is a functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC® research and development; incorporates an E3 ligase ligand plus an alkylC6 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data

M.Wt:
704.72
Formula:
C32H46FN5O5S.2HCl
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
2564467-16-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under licence from the University of Dundee.

Product Datasheets

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