Vinpocetine

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
   Fox JT, Sakamuru S, Huang R
   Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
2. Vinpocetine inhibits Streptococcus pneumoniae-induced upregulation of mucin MUC5AC expression via induction of MKP-1 phosphatase in the pathogenesis of otitis media.
   Lee J, Komatsu K, Lee B, Miyata M, O'Neill Bohn A, Xu H, Yan C, Li J
   J Immunol, 2015;194(12):5990-8.
3. Effect of vinpocetine on cyclic nucleotide metabolism in vascular smooth muscle.
   Hagiwara et al.
   Biochem.Pharmacol., 1984;33:453
4. Vinpocetine is as potent as phen. to block voltage-gated Na⁺ channels in rat cortical neurons.
   Molnar and Erdo
   Eur.J.Pharmacol., 1995;273:303

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