VU 0542270

Catalog # Availability Size / Price Qty
8151/10
8151/50
VU 0542270 | CAS No. 1396814-79-1 | Inward Rectifier Potassium Channel Activators
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Description: Selective inhibitor of Kir6.1 KATP channels

Chemical Name: 1-[(4-Methyl-2-thiophen-2-yl-1,3-thiazol-5-yl)methyl]-3-thiophen-2-ylurea

Purity: ≥98%

Product Details
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Biological Activity

VU 0542270 is a selective inhibitor of Kir6.1/SUR2B KATP channels (IC50 = 104 nM). Shows no activity at other Kir channel types at up to 30 μM. Dose-dependently induces constriction of ductus arteriosus vessels.

Technical Data

M.Wt:
335.46
Formula:
C14H13N3OS3
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
1396814-79-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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