VU 0542270 New
Chemical Name: 1-[(4-Methyl-2-thiophen-2-yl-1,3-thiazol-5-yl)methyl]-3-thiophen-2-ylurea
Purity: ≥98%
Biological Activity
VU 0542270 is a selective inhibitor of Kir6.1/SUR2B KATP channels (IC50 = 104 nM). Shows no activity at other Kir channel types at up to 30 μM. Dose-dependently induces constriction of ductus arteriosus vessels.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
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