YE 120

Catalog # Availability Size / Price Qty
4457/10
4457/50
YE 120 | CAS No. 383124-82-1 | Orphan 7-TM Receptor Agonists
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Description: GPR35 agonist

Chemical Name: 2-[3-Cyano-5-(3,4-dichlorophenyl)-4,5-dimethyl-2(5H)-furanylidene]propanedinitrile

Purity: ≥98%

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Biological Activity

YE 120 is a GPR35 agonist (EC50 = 32 nM in DMR assays). Also displays partial agonist activity in a β-arrestin translocation assay (EC50 = 10.2 μM).

Technical Data

M.Wt:
330.17
Formula:
C16H9Cl2N3O
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
383124-82-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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